Effects of oestrogen on gene expression in epithelium and stroma of normal human breast tissue

Endocrine-Related Cancer

Volumn 13, Issue 2, 2006, Pages 617-628

  Wilson, C L ^a   Sims, A H ^b   Howell, A ^b   Miller, C J ^a   Clarke, R B ^b  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA;

ADOLESCENT; ADULT; AGR2 GENE; ANIMAL EXPERIMENT; AREG GENE; ARTICLE; BREAST; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM; EXTRACELLULAR MATRIX; FEMALE; GENE; GENE EXPRESSION; GREB1 GENE; HUMAN; HUMAN TISSUE; HYBRIDIZATION; IMMUNOHISTOCHEMISTRY; KRT19 GENE; MAMMOGLOBIN GENE; MENSTRUAL CYCLE; MORPHOMETRICS; MOUSE; NONHUMAN; RNA ISOLATION; SCHOOL CHILD; STROMA; TFF1 GENE; UPREGULATION; XBP 1 GENE; XENOGRAFT;

ADULT; ANIMALS; BREAST; EPITHELIUM; ESTRADIOL; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMANS; MICE; MICE, NUDE; STROMAL CELLS; TRANSPLANTATION, HETEROLOGOUS;

EID: 33745106870     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/erc.1.01165     Document Type: Article

References (46)

1. Allinen M, Beroukhim R, Cai L, Brennan C, Lahti-Domenici J, Huang H, Porter D, Hu M, Chin L, Richardson A et al. 2004 Molecular characterization of the tumor microenvironment in breast cancer. Cancer Cell 6 17-32.
2. Anderson E, Clarke RB & Howell A 1998 Estrogen responsiveness and control of normal human breast proliferation. Journal of Mammary Gland Biology Neoplasia 3 23-35.
3. Armes JE & Venter DJ 2002 The pathology of inherited breast cancer. Pathology 34 309-314.
4. Ben-Baruch A 2003 Host microenvironment in breast cancer development: inflammatory cells, cytokines and chemokines in breast cancer progression: reciprocal tumor-microenvironment interactions. Breast Cancer Research 5 31-36.
5. Breitling R, Armengaud P, Amtmann A & Herzyk P 2004 Rank products: a simple, yet powerful, new method to detect differentially regulated genes in replicated microarray experiments. FEBS Letters 573 83-92.
6. Brown LF, Guidi AJ, Schnitt SJ, Van De Water L, Iruela-Arispe ML, Yeo TK, Tognazzi K & Dvorak HF 1999 Vascular stroma formation in carcinoma in situ, invasive carcinoma, and metastatic carcinoma of the breast. Clinical Cancer Research 5 1041-1056.
7. Choe SE, Boutros M, Michelson AM, Church GM & Halfon MS 2005 Preferred analysis methods for Affymetrix GeneChips revealed by a wholly defined control dataset. Genome Biology 6 R16.
8. Clarke RB, Howell A & Anderson E 1997 Estrogen sensitivity of normal human breast tissue in vivo and implanted into athymic nude mice: analysis of the relationship between estrogen-induced proliferation and progesterone receptor expression. Breast Cancer Research Treatment 45 121-133.
9. Clarke RB, Anderson E & Howell A 2004 Steroid receptors in human breast cancer. Trends in Endocrinology Metabolism 15 316-323.
10. Clarke RB, Spence K, Anderson E, Howell A, Okano H & Potten CS 2005 A putative human breast stem cell population is enriched for steroid receptor-positive cells. Developmental Biology 277 443-456.
11. Coser KR, Chesnes J, Hur J, Ray S, Isselbacher KJ & Shioda T 2003 Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray. PNAS 100 13994-13999.
12. Creighton C, Kuick R, Misek DE, Rickman DS, Brichory FM, Rouillard JM, Omenn GS & Hanash S 2003 Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice. Genome Biology 4 R46.
13. Creighton CJ, Bromberg-White JL, Misek DE, Monsma DJ, Brichory F, Kuick R, Giordano TJ, Gao W, Omenn GS, Webb CP et al. 2005 Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation. Molecular Cancer Research 3 119-129.
14. Crosier M, Scott D, Wilson RG, Griffiths CD, May FE & Westley BR 2001 High expression of the trefoil protein TFFl in interval breast cancers. American Journal of Pathology 159 215-221.
15. Frasor J, Danes JM, Komm B, Chang KC, Lyttle CR & Katzenellenbogen BS 2003 Profiling of estrogen up- and down-regulated gene expression in human breast cancer cells: insights into gene networks and pathways underlying estrogenic control of proliferation and cell phenotype. Endocrinology 144 4562-4574.
16. Frasor J, Stossi F, Danes JM, Komm B, Lyttle CR & Katzenellenbogen BS 2004 Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells. Cancer Research 64 1522-1533.
17. Gudjonsson T, Villadsen R, Nielsen HL, Ronnov-Jessen L, Bissell MJ & Petersen OW 2002 Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties. Genes and Development 16 693-706.
18. Harvell DM, Richer JK, Allred DC, Sartorius CA & Horwitz KB 2006 Estradiol regulates different genes in human breast tumor xenografts compared to the identical cells in culture. Endocrinology 147 700-713.
19. Howell A, Sims AH, Ong KR, Harvie M, Evans DG & Clarke RB 2005 Mechanisms of Disease: prediction and prevention of breast cancer - cellular and molecular interactions. Nature Clinical Practice Oncology 2 635-646.
20. Hutson SW, Cowen PN & Bird CC 1985 Morphometric studies of age related changes in normal human breast and their significance for evolution of mammary cancer. Journal of Clinical Pathology 38 281-287.
21. Ihaka R & Gentleman R 1996 R: a language for data analysis and graphics. Journal of Computational and Graphical Statistics 5 299-314.
22. Inoue A, Yoshida N, Omoto Y, Oguchi S, Yamori T, Kiyama R & Hayashi S 2002 Development of cDNA microarray for expression profiling of estrogen-responsive genes. Journal of Molecular Endocrinology 29 175-192.
23. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, Scherf U & Speed TP 2003 Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biosiatistics 4 249-264.
24. Jones C, Mackay A, Grigoriadis A, Cossu A, Reis-Filho JS, Fulford L, Dexter T, Davies S, Bulmer K, Ford E et al. 2004 Expression profiling of purified normal human luminal and myoepithelial breast cells: identification of novel prognostic markers for breast cancer. Cancer Research 64 3037-3045.
25. Kang H, Watkins G, Parr C. Douglas-Jones A, Mansel RE & Jiang WG 2005 Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer. Breast Cancer Research 7 R402-R410.
26. Kuang WW, Thompson DA, Hoch RV & Weigel RJ 1998 Differential screening and suppression subtractive hybridization identified genes differentially expressed in an estrogen receptor-positive breast carcinoma cell line. Nucleic Acids Research 26 1116-1123.
27. Lacroix M & Leclercq G 2004 About GATA3, HNF3A, and XBP1, three genes co-expressed with the oestrogen receptor-alpha gene (ESR1) in breast cancer. Molecular and Cellular Endocrinology 219 1-7.
28. Laidlaw IJ, Clarke RB, Howell A. Owen AW, Potten CS & Anderson E 1995 The proliferation of normal human breast tissue implanted into athymic nude mice is stimulated by estrogen but not progesterone. Endocrinology 136 164-171.
29. Lin CY, Strom A, Vega VB, Kong SL, Yeo AL. Thomsen JS, Chan WC. Doray B, Bangarusamy DK, Ramasamy A et al. 2004 Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells. Genome Biology 5 R66.
30. Liu D, Rudland PS, Sibson DR, Platt-Higgins A & Barraclough R 2005 Human homologue of cement gland protein, a novel metastasis inducer associated with breast carcinomas. Cancer Research 65 3796-3805.
31. McManus MJ & Welsch CW 1984 The effect of estrogen, progesterone, thyroxine, and human placental lactogen on DNA synthesis of human breast ductal epithelium maintained in athymic nude mice. Cancer 54 1920-1927.
32. Potten CS, Watson RJ, Williams GT, Tickle S, Roberts SA, Harris M & Howell A 1988 The effect of age and menstrual cycle upon proliferative activity of the normal human breast. British Journal of Cancer 58 163-170.
33. Prest SJ, May FE & Westley BR 2002 The estrogen-regulated protein, TFF1, stimulates migration of human breast cancer cells. FASEB Journal 16 592-594.
34. Ring AE, Zabaglo L, Ormerod MG. Smith IE & Dowsett M 2005 Detection of circulating epithelial cells in the blood of patients with breast cancer: comparison of three techniques. British Journal of Cancer 92 906-912.
35. Rodrigues S, Nguyen QD, Faivre S, Bruyneel E, Thim L, Westley B, May F, Flatau G, Mareel M, Gespach C et al. 2001 Activation of cellular invasion by trefoil peptides and src is mediated by cyclooxygenase- and thromboxane A2 receptor-dependent signaling pathways. FASEB Journal 15 1517-1528.
36. Sasik R, Calvo E & Corbeil J 2002 Statistical analysis of high-density oligonucleotide arrays: a multiplicative noise model. Bioinformatics 18 1633-1640.
37. Seth P. Porter D, Lahti-Domenici J, Geng Y, Richardson A & Polyak K 2002 Cellular and molecular targets of estrogen in normal human breast tissue. Cancer Research 62 4540-4544.
38. Shekhar MP, Werdell J, Santner SJ. Pauley RJ & Tait L 2001 Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression. Cancer Research 61 1320-1326.
39. Shoker BS, Jarvis C, Clarke RB, Anderson E, Hewlett J, Davies MP, Sibson DR & Sloane JP 1999 Estrogen receptor-positive proliferating cells in the normal and precancerous breast. American Journal of Pathology 155 1811-1815.
40. Sternlicht MD, Sunnarborg SW, Kouros-Mehr H, Yu Y, Lee DC & Werb Z 2005 Mammary ductal morphogenesis requires paracrine activation of stromal EGFR via ADAM17-dependent shedding of epithelial amphiregulin. Development 132 3923-3933.
41. Vendrell JA, Magnino F, Danis E, Duchesne MJ, Pinloche S, Pons M, Birnbaum D, Nguyen C, Theillet C & Cohen PA 2004 Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation. Journal of Molecular Endocrinology 32 397-414.
42. Wilson CL & Miller CJ 2005 Simpleaffy: a BioConductor package for Affymetrix Quality Control and data analysis. Bioinformatics 21 3683-3685.
43. Wiseman BS & Werb Z 2002 Stromal effects on mammary gland development and breast cancer. Science 296 1046-1049.
44. Wright NA, Poulsom R, Stamp G, Van Noorden S, Sarraf C, Elia G. Ahnen D, Jeffery R, Longcroft J, Pike C et al. 1993 Trefoil peptide gene expression in gastrointestinal epithelial cells in inflammatory bowel disease. Gastroenterology 104 12-20.
45. Xu J. Fan S & Rosen EM 2005 Regulation of the estrogen-inducible gene expression profile by the breast cancer susceptibility gene BRCA1. Endocrinology 146 2031-2047.
46. Yavelow J, Tuccillo A, Kadner SS, Katz J & Finlay TH 1997 Alpha 1-antitrypsin blocks the release of transforming growth factor-alpha from MCF-7 human breast cancer cells. Journal of Clinical Endocrinology and Metabolism 82 745-752.