메뉴 건너뛰기




Volumn 170, Issue 1, 2013, Pages 222-232

Benzodiazepine-site pharmacology on GABAA receptors in histaminergic neurons

Author keywords

GABA; histamine; microelectrode array; single cell RT PCR; whole cell patch clamp; zolpidem

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 ETHYL 6,7 DIMETHOXY BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER; CHLORDIAZEPOXIDE; DIAZEPAM; FLUMAZENIL; MIDAZOLAM; ZOLPIDEM;

EID: 84881650157     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12280     Document Type: Article
Times cited : (13)

References (57)
  • 1
    • 39749083327 scopus 로고    scopus 로고
    • Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila
    • Agosto J, Choi JC, Parisky KM, Stilwell G, Rosbash M, Griffith LC, (2008). Modulation of GABAA receptor desensitization uncouples sleep onset and maintenance in Drosophila. Nat Neurosci 11: 354-359.
    • (2008) Nat Neurosci , vol.11 , pp. 354-359
    • Agosto, J.1    Choi, J.C.2    Parisky, K.M.3    Stilwell, G.4    Rosbash, M.5    Griffith, L.C.6
  • 2
    • 70949083914 scopus 로고    scopus 로고
    • Orexin/hypocretin and histamine: Distinct roles in the control of wakefulness demonstrated using knock-out mouse models
    • Anaclet C, Parmentier R, Ouk K, Guidon G, Buda C, Sastre JP, et al. (2009). Orexin/hypocretin and histamine: distinct roles in the control of wakefulness demonstrated using knock-out mouse models. J Neurosci 29: 14423-14438.
    • (2009) J Neurosci , vol.29 , pp. 14423-14438
    • Anaclet, C.1    Parmentier, R.2    Ouk, K.3    Guidon, G.4    Buda, C.5    Sastre, J.P.6
  • 3
    • 84863015290 scopus 로고    scopus 로고
    • Effects of GF-015535-00, a novel alpha1 GABA A receptor ligand, on the sleep-wake cycle in mice, with reference to zolpidem
    • Anaclet C, Zhang M, Zhao C, Buda C, Seugnet L, Lin JS, (2012). Effects of GF-015535-00, a novel alpha1 GABA A receptor ligand, on the sleep-wake cycle in mice, with reference to zolpidem. Sleep 35: 103-111.
    • (2012) Sleep , vol.35 , pp. 103-111
    • Anaclet, C.1    Zhang, M.2    Zhao, C.3    Buda, C.4    Seugnet, L.5    Lin, J.S.6
  • 4
    • 0033063516 scopus 로고    scopus 로고
    • Risk of sedation for upper GI endoscopy exacerbating subclinical hepatic encephalopathy in patients with cirrhosis
    • Assy N, Rosser BG, Grahame GR, Minuk GY, (1999). Risk of sedation for upper GI endoscopy exacerbating subclinical hepatic encephalopathy in patients with cirrhosis. Gastrointest Endosc 49: 690-694.
    • (1999) Gastrointest Endosc , vol.49 , pp. 690-694
    • Assy, N.1    Rosser, B.G.2    Grahame, G.R.3    Minuk, G.Y.4
  • 5
    • 0037195864 scopus 로고    scopus 로고
    • Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement
    • Baumann SW, Baur R, Sigel E, (2002). Forced subunit assembly in alpha1beta2gamma2 GABAA receptors. Insight into the absolute arrangement. J Biol Chem 277: 46020-46025.
    • (2002) J Biol Chem , vol.277 , pp. 46020-46025
    • Baumann, S.W.1    Baur, R.2    Sigel, E.3
  • 6
    • 0029998387 scopus 로고    scopus 로고
    • Point mutations of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid(A) receptor affecting modulation of the channel by ligands of the benzodiazepine binding site
    • Buhr A, Baur R, Malherbe P, Sigel E, (1996). Point mutations of the alpha 1 beta 2 gamma 2 gamma-aminobutyric acid(A) receptor affecting modulation of the channel by ligands of the benzodiazepine binding site. Mol Pharmacol 49: 1080-1084.
    • (1996) Mol Pharmacol , vol.49 , pp. 1080-1084
    • Buhr, A.1    Baur, R.2    Malherbe, P.3    Sigel, E.4
  • 7
    • 0030959309 scopus 로고    scopus 로고
    • Subtle changes in residue 77 of the gamma subunit of alpha1beta2gamma2 GABAA receptors drastically alter the affinity for ligands of the benzodiazepine binding site
    • Buhr A, Baur R, Sigel E, (1997). Subtle changes in residue 77 of the gamma subunit of alpha1beta2gamma2 GABAA receptors drastically alter the affinity for ligands of the benzodiazepine binding site. J Biol Chem 272: 11799-11804.
    • (1997) J Biol Chem , vol.272 , pp. 11799-11804
    • Buhr, A.1    Baur, R.2    Sigel, E.3
  • 8
    • 2542457485 scopus 로고    scopus 로고
    • Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit
    • Cope DW, Wulff P, Oberto A, Aller MI, Capogna M, Ferraguti F, et al. (2004). Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit. Neuropharmacology 47: 17-34.
    • (2004) Neuropharmacology , vol.47 , pp. 17-34
    • Cope, D.W.1    Wulff, P.2    Oberto, A.3    Aller, M.I.4    Capogna, M.5    Ferraguti, F.6
  • 9
    • 0036707590 scopus 로고    scopus 로고
    • Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists
    • Crestani F, Assandri R, Tauber M, Martin JR, Rudolph U, (2002). Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists. Neuropharmacology 43: 679-684.
    • (2002) Neuropharmacology , vol.43 , pp. 679-684
    • Crestani, F.1    Assandri, R.2    Tauber, M.3    Martin, J.R.4    Rudolph, U.5
  • 10
    • 0025612316 scopus 로고
    • Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+
    • Draguhn A, Verdorn TA, Ewert M, Seeburg PH, Sakmann B, (1990). Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+. Neuron 5: 781-788.
    • (1990) Neuron , vol.5 , pp. 781-788
    • Draguhn, A.1    Verdorn, T.A.2    Ewert, M.3    Seeburg, P.H.4    Sakmann, B.5
  • 11
    • 0037460615 scopus 로고    scopus 로고
    • The efficacy of flumazenil in subclinical to mild hepatic encephalopathic ambulatory patients. A prospective, randomised, double-blind, placebo-controlled study
    • Dursun M, Caliskan M, Canoruc F, Aluclu U, Canoruc N, Tuzcu A, et al. (2003). The efficacy of flumazenil in subclinical to mild hepatic encephalopathic ambulatory patients. A prospective, randomised, double-blind, placebo-controlled study. Swiss Med Wkly 133: 118-123.
    • (2003) Swiss Med Wkly , vol.133 , pp. 118-123
    • Dursun, M.1    Caliskan, M.2    Canoruc, F.3    Aluclu, U.4    Canoruc, N.5    Tuzcu, A.6
  • 12
    • 33644665247 scopus 로고    scopus 로고
    • Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin
    • Essrich C, Lorez M, Benson JA, Fritschy JM, Luscher B, (1998). Postsynaptic clustering of major GABAA receptor subtypes requires the gamma 2 subunit and gephyrin. Nat Neurosci 1: 563-571.
    • (1998) Nat Neurosci , vol.1 , pp. 563-571
    • Essrich, C.1    Lorez, M.2    Benson, J.A.3    Fritschy, J.M.4    Luscher, B.5
  • 13
    • 14844323722 scopus 로고    scopus 로고
    • Variations on an inhibitory theme: Phasic and tonic activation of GABA(A) receptors
    • Farrant M, Nusser Z, (2005). Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors. Nat Rev Neurosci 6: 215-229.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 215-229
    • Farrant, M.1    Nusser, Z.2
  • 14
    • 0029097465 scopus 로고
    • Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors
    • Gunther U, Benson J, Benke D, Fritschy JM, Reyes G, Knoflach F, et al. (1995). Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors. Proc Natl Acad Sci U S A 92: 7749-7753.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7749-7753
    • Gunther, U.1    Benson, J.2    Benke, D.3    Fritschy, J.M.4    Reyes, G.5    Knoflach, F.6
  • 15
    • 0037315955 scopus 로고    scopus 로고
    • The role of histamine and the tuberomamillary nucleus in the nervous system
    • Haas H, Panula P, (2003). The role of histamine and the tuberomamillary nucleus in the nervous system. Nat Rev Neurosci 4: 121-130.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 121-130
    • Haas, H.1    Panula, P.2
  • 17
    • 84866314954 scopus 로고    scopus 로고
    • Midazolam for sedation during diagnostic or therapeutic upper gastrointestinal endoscopy in cirrhotic patients
    • Haq MM, Faisal N, Khalil A, Haqqi SA, Shaikh H, Arain N, (2012). Midazolam for sedation during diagnostic or therapeutic upper gastrointestinal endoscopy in cirrhotic patients. Eur J Gastroenterol Hepatol 24: 1214-1218.
    • (2012) Eur J Gastroenterol Hepatol , vol.24 , pp. 1214-1218
    • Haq, M.M.1    Faisal, N.2    Khalil, A.3    Haqqi, S.A.4    Shaikh, H.5    Arain, N.6
  • 19
    • 0029882456 scopus 로고    scopus 로고
    • Zolpidem functionally discriminates subtypes of native GABAA receptors in acutely dissociated rat striatal and cerebellar neurons
    • Itier V, Depoortere H, Scatton B, Avenet P, (1996). Zolpidem functionally discriminates subtypes of native GABAA receptors in acutely dissociated rat striatal and cerebellar neurons. Neuropharmacology 35: 137-145.
    • (1996) Neuropharmacology , vol.35 , pp. 137-145
    • Itier, V.1    Depoortere, H.2    Scatton, B.3    Avenet, P.4
  • 21
    • 84876955433 scopus 로고    scopus 로고
    • Partial agonism of taurine at gamma-containing native and recombinant GABAA receptors
    • Kletke O, Gisselmann G, May A, Hatt H, Sergeeva OA, (2013). Partial agonism of taurine at gamma-containing native and recombinant GABAA receptors. PLoS ONE 8: e61733.
    • (2013) PLoS ONE , vol.8
    • Kletke, O.1    Gisselmann, G.2    May, A.3    Hatt, H.4    Sergeeva, O.A.5
  • 22
    • 0033932980 scopus 로고    scopus 로고
    • Flumazenil in the treatment of acute hepatic encephalopathy in cirrhotic patients: A double blind randomized placebo controlled study
    • Laccetti M, Manes G, Uomo G, Lioniello M, Rabitti PG, Balzano A, (2000). Flumazenil in the treatment of acute hepatic encephalopathy in cirrhotic patients: a double blind randomized placebo controlled study. Dig Liver Dis 32: 335-338.
    • (2000) Dig Liver Dis , vol.32 , pp. 335-338
    • Laccetti, M.1    Manes, G.2    Uomo, G.3    Lioniello, M.4    Rabitti, P.G.5    Balzano, A.6
  • 23
    • 0026615268 scopus 로고
    • The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development
    • Laurie DJ, Wisden W, Seeburg PH, (1992). The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development. J Neurosci 12: 4151-4172.
    • (1992) J Neurosci , vol.12 , pp. 4151-4172
    • Laurie, D.J.1    Wisden, W.2    Seeburg, P.H.3
  • 24
    • 80052424153 scopus 로고    scopus 로고
    • Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-gamma2-dependent modulation
    • Leppa E, Linden AM, Rabe H, Vekovischeva OY, Wulff P, Luddens H, et al. (2011). Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-gamma2-dependent modulation. Eur J Pharmacol 666: 111-121.
    • (2011) Eur J Pharmacol , vol.666 , pp. 111-121
    • Leppa, E.1    Linden, A.M.2    Rabe, H.3    Vekovischeva, O.Y.4    Wulff, P.5    Luddens, H.6
  • 25
    • 0033841514 scopus 로고    scopus 로고
    • Single-channel properties of neuronal GABAA receptors from mice lacking the 2 subunit
    • Lorez M, Benke D, Luscher B, Mohler H, Benson JA, (2000). Single-channel properties of neuronal GABAA receptors from mice lacking the 2 subunit. J Physiol 527 (Pt 1): 11-31.
    • (2000) J Physiol , vol.527 , Issue.PART 1 , pp. 11-31
    • Lorez, M.1    Benke, D.2    Luscher, B.3    Mohler, H.4    Benson, J.A.5
  • 26
    • 0025328092 scopus 로고
    • GABAA-receptor expressed from rat brain alpha- and beta-subunit cDNAs displays potentiation by benzodiazepine receptor ligands
    • Malherbe P, Draguhn A, Multhaup G, Beyreuther K, Mohler H, (1990). GABAA-receptor expressed from rat brain alpha- and beta-subunit cDNAs displays potentiation by benzodiazepine receptor ligands. Brain Res Mol Brain Res 8: 199-208.
    • (1990) Brain Res Mol Brain Res , vol.8 , pp. 199-208
    • Malherbe, P.1    Draguhn, A.2    Multhaup, G.3    Beyreuther, K.4    Mohler, H.5
  • 27
    • 84875791515 scopus 로고    scopus 로고
    • Ontogeny repeats the phylogenetic recruitment of the cargo exporter cornichon into AMPA receptor signaling complexes
    • Mauric V, Molders A, Harmel N, Heimrich B, Sergeeva OA, Klocker N, (2013). Ontogeny repeats the phylogenetic recruitment of the cargo exporter cornichon into AMPA receptor signaling complexes. Mol Cell Neurosci 56C: 10-17.
    • (2013) Mol Cell Neurosci , vol.56 C , pp. 10-17
    • Mauric, V.1    Molders, A.2    Harmel, N.3    Heimrich, B.4    Sergeeva, O.A.5    Klocker, N.6
  • 28
    • 4644319039 scopus 로고    scopus 로고
    • Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit
    • Ogris W, Poltl A, Hauer B, Ernst M, Oberto A, Wulff P, et al. (2004). Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit. Biochem Pharmacol 68: 1621-1629.
    • (2004) Biochem Pharmacol , vol.68 , pp. 1621-1629
    • Ogris, W.1    Poltl, A.2    Hauer, B.3    Ernst, M.4    Oberto, A.5    Wulff, P.6
  • 29
    • 56349145622 scopus 로고    scopus 로고
    • PDF cells are a GABA-responsive wake-promoting component of the Drosophila sleep circuit
    • Parisky KM, Agosto J, Pulver SR, Shang Y, Kuklin E, Hodge JJ, et al. (2008). PDF cells are a GABA-responsive wake-promoting component of the Drosophila sleep circuit. Neuron 60: 672-682.
    • (2008) Neuron , vol.60 , pp. 672-682
    • Parisky, K.M.1    Agosto, J.2    Pulver, S.R.3    Shang, Y.4    Kuklin, E.5    Hodge, J.J.6
  • 30
    • 0036759585 scopus 로고    scopus 로고
    • Anatomical, physiological, and pharmacological characteristics of histidine decarboxylase knock-out mice: Evidence for the role of brain histamine in behavioral and sleep-wake control
    • Parmentier R, Ohtsu H, Djebbara-Hannas Z, Valatx JL, Watanabe T, Lin JS, (2002). Anatomical, physiological, and pharmacological characteristics of histidine decarboxylase knock-out mice: evidence for the role of brain histamine in behavioral and sleep-wake control. J Neurosci 22: 7695-7711.
    • (2002) J Neurosci , vol.22 , pp. 7695-7711
    • Parmentier, R.1    Ohtsu, H.2    Djebbara-Hannas, Z.3    Valatx, J.L.4    Watanabe, T.5    Lin, J.S.6
  • 31
    • 65549114213 scopus 로고    scopus 로고
    • Excitation of histaminergic tuberomamillary neurons by thyrotropin-releasing hormone
    • Parmentier R, Kolbaev S, Klyuch BP, Vandael D, Lin JS, Selbach O, et al. (2009). Excitation of histaminergic tuberomamillary neurons by thyrotropin-releasing hormone. J Neurosci 29: 4471-4483.
    • (2009) J Neurosci , vol.29 , pp. 4471-4483
    • Parmentier, R.1    Kolbaev, S.2    Klyuch, B.P.3    Vandael, D.4    Lin, J.S.5    Selbach, O.6
  • 32
    • 33744505947 scopus 로고    scopus 로고
    • Cell-attached voltage-clamp and current-clamp recording and stimulation techniques in brain slices
    • Perkins KL, (2006). Cell-attached voltage-clamp and current-clamp recording and stimulation techniques in brain slices. J Neurosci Methods 154: 1-18.
    • (2006) J Neurosci Methods , vol.154 , pp. 1-18
    • Perkins, K.L.1
  • 33
    • 0025815813 scopus 로고
    • Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents
    • Puia G, Vicini S, Seeburg PH, Costa E, (1991). Influence of recombinant gamma-aminobutyric acid-A receptor subunit composition on the action of allosteric modulators of gamma-aminobutyric acid-gated Cl- currents. Mol Pharmacol 39: 691-696.
    • (1991) Mol Pharmacol , vol.39 , pp. 691-696
    • Puia, G.1    Vicini, S.2    Seeburg, P.H.3    Costa, E.4
  • 34
    • 77952675421 scopus 로고    scopus 로고
    • The point mutation gamma 2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABAA receptor subtypes
    • Ramerstorfer J, Furtmuller R, Vogel E, Huck S, Sieghart W, (2010). The point mutation gamma 2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABAA receptor subtypes. Eur J Pharmacol 636: 18-27.
    • (2010) Eur J Pharmacol , vol.636 , pp. 18-27
    • Ramerstorfer, J.1    Furtmuller, R.2    Vogel, E.3    Huck, S.4    Sieghart, W.5
  • 35
    • 30844456191 scopus 로고    scopus 로고
    • GABA-based therapeutic approaches: GABAA receptor subtype functions
    • Rudolph U, Mohler H, (2006). GABA-based therapeutic approaches: GABAA receptor subtype functions. Curr Opin Pharmacol 6: 18-23.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 18-23
    • Rudolph, U.1    Mohler, H.2
  • 36
    • 27644457084 scopus 로고    scopus 로고
    • Hypothalamic regulation of sleep and circadian rhythms
    • Saper CB, Scammell TE, Lu J, (2005). Hypothalamic regulation of sleep and circadian rhythms. Nature 437: 1257-1263.
    • (2005) Nature , vol.437 , pp. 1257-1263
    • Saper, C.B.1    Scammell, T.E.2    Lu, J.3
  • 37
    • 84884791457 scopus 로고    scopus 로고
    • GABAergic transmission in hepatic encephalopathy
    • doi: 10.1016/j.abb.2013.04.005
    • Sergeeva OA, (2013). GABAergic transmission in hepatic encephalopathy. Arch Biochem Biophys doi: 10.1016/j.abb.2013.04.005.
    • (2013) Arch Biochem Biophys
    • Sergeeva, O.A.1
  • 39
    • 12144284564 scopus 로고    scopus 로고
    • Pharmacological properties of GABAA receptors in rat hypothalamic neurons expressing the epsilon-subunit
    • Sergeeva OA, Andreeva N, Garret M, Scherer A, Haas HL, (2005). Pharmacological properties of GABAA receptors in rat hypothalamic neurons expressing the epsilon-subunit. J Neurosci 25: 88-95.
    • (2005) J Neurosci , vol.25 , pp. 88-95
    • Sergeeva, O.A.1    Andreeva, N.2    Garret, M.3    Scherer, A.4    Haas, H.L.5
  • 41
    • 0032526450 scopus 로고    scopus 로고
    • Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat
    • Sherin JE, Elmquist JK, Torrealba F, Saper CB, (1998). Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat. J Neurosci 18: 4705-4721.
    • (1998) J Neurosci , vol.18 , pp. 4705-4721
    • Sherin, J.E.1    Elmquist, J.K.2    Torrealba, F.3    Saper, C.B.4
  • 42
    • 0036676629 scopus 로고    scopus 로고
    • Mapping of the benzodiazepine recognition site on GABA(A) receptors
    • Sigel E, (2002). Mapping of the benzodiazepine recognition site on GABA(A) receptors. Curr Top Med Chem 2: 833-839.
    • (2002) Curr Top Med Chem , vol.2 , pp. 833-839
    • Sigel, E.1
  • 43
    • 0029417325 scopus 로고
    • Beta-Carboline gamma-aminobutyric acidA receptor inverse agonists modulate gamma-aminobutyric acid via the loreclezole binding site as well as the benzodiazepine site
    • Stevenson A, Wingrove PB, Whiting PJ, Wafford KA, (1995). beta-Carboline gamma-aminobutyric acidA receptor inverse agonists modulate gamma-aminobutyric acid via the loreclezole binding site as well as the benzodiazepine site. Mol Pharmacol 48: 965-969.
    • (1995) Mol Pharmacol , vol.48 , pp. 965-969
    • Stevenson, A.1    Wingrove, P.B.2    Whiting, P.J.3    Wafford, K.A.4
  • 44
    • 0036211070 scopus 로고    scopus 로고
    • Tracazolate reveals a novel type of allosteric interaction with recombinant gamma-aminobutyric acid(A) receptors
    • Thompson SA, Wingrove PB, Connelly L, Whiting PJ, Wafford KA, (2002). Tracazolate reveals a novel type of allosteric interaction with recombinant gamma-aminobutyric acid(A) receptors. Mol Pharmacol 61: 861-869.
    • (2002) Mol Pharmacol , vol.61 , pp. 861-869
    • Thompson, S.A.1    Wingrove, P.B.2    Connelly, L.3    Whiting, P.J.4    Wafford, K.A.5
  • 46
    • 44449104126 scopus 로고    scopus 로고
    • Emerging anti-insomnia drugs: Tackling sleeplessness and the quality of wake time
    • Wafford KA, Ebert B, (2008). Emerging anti-insomnia drugs: tackling sleeplessness and the quality of wake time. Nat Rev Drug Discov 7: 530-540.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 530-540
    • Wafford, K.A.1    Ebert, B.2
  • 47
    • 0027328861 scopus 로고
    • Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors
    • Wafford KA, Bain CJ, Whiting PJ, Kemp JA, (1993). Functional comparison of the role of gamma subunits in recombinant human gamma-aminobutyric acidA/benzodiazepine receptors. Mol Pharmacol 44: 437-442.
    • (1993) Mol Pharmacol , vol.44 , pp. 437-442
    • Wafford, K.A.1    Bain, C.J.2    Whiting, P.J.3    Kemp, J.A.4
  • 48
    • 0033623608 scopus 로고    scopus 로고
    • Benzodiazepines act on GABAA receptors via two distinct and separable mechanisms
    • Walters RJ, Hadley SH, Morris KD, Amin J, (2000). Benzodiazepines act on GABAA receptors via two distinct and separable mechanisms. Nat Neurosci 3: 1274-1281.
    • (2000) Nat Neurosci , vol.3 , pp. 1274-1281
    • Walters, R.J.1    Hadley, S.H.2    Morris, K.D.3    Amin, J.4
  • 49
    • 0030779570 scopus 로고    scopus 로고
    • Key amino acids in the gamma subunit of the gamma-aminobutyric acidA receptor that determine ligand binding and modulation at the benzodiazepine site
    • Wingrove PB, Thompson SA, Wafford KA, Whiting PJ, (1997). Key amino acids in the gamma subunit of the gamma-aminobutyric acidA receptor that determine ligand binding and modulation at the benzodiazepine site. Mol Pharmacol 52: 874-881.
    • (1997) Mol Pharmacol , vol.52 , pp. 874-881
    • Wingrove, P.B.1    Thompson, S.A.2    Wafford, K.A.3    Whiting, P.J.4
  • 50
    • 0026612363 scopus 로고
    • The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon
    • Wisden W, Laurie DJ, Monyer H, Seeburg PH, (1992). The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. I. Telencephalon, diencephalon, mesencephalon. J Neurosci 12: 1040-1062.
    • (1992) J Neurosci , vol.12 , pp. 1040-1062
    • Wisden, W.1    Laurie, D.J.2    Monyer, H.3    Seeburg, P.H.4
  • 51
    • 34347347075 scopus 로고    scopus 로고
    • From synapse to behavior: Rapid modulation of defined neuronal types with engineered GABAA receptors
    • Wulff P, Goetz T, Leppa E, Linden AM, Renzi M, Swinny JD, et al. (2007). From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors. Nat Neurosci 10: 923-929.
    • (2007) Nat Neurosci , vol.10 , pp. 923-929
    • Wulff, P.1    Goetz, T.2    Leppa, E.3    Linden, A.M.4    Renzi, M.5    Swinny, J.D.6
  • 52
    • 62549113093 scopus 로고    scopus 로고
    • Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons
    • Wulff P, Ponomarenko AA, Bartos M, Korotkova TM, Fuchs EC, Bahner F, et al. (2009). Hippocampal theta rhythm and its coupling with gamma oscillations require fast inhibition onto parvalbumin-positive interneurons. Proc Natl Acad Sci U S A 106: 3561-3566.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 3561-3566
    • Wulff, P.1    Ponomarenko, A.A.2    Bartos, M.3    Korotkova, T.M.4    Fuchs, E.C.5    Bahner, F.6
  • 53
    • 84856697479 scopus 로고    scopus 로고
    • GABAA receptors involved in sleep and anaesthesia: Beta1- versus beta3-containing assemblies
    • Yanovsky Y, Schubring S, Fleischer W, Gisselmann G, Zhu XR, Lubbert H, et al. (2012a). GABAA receptors involved in sleep and anaesthesia: beta1- versus beta3-containing assemblies. Pflugers Arch 463: 187-199.
    • (2012) Pflugers Arch , vol.463 , pp. 187-199
    • Yanovsky, Y.1    Schubring, S.2    Fleischer, W.3    Gisselmann, G.4    Zhu, X.R.5    Lubbert, H.6
  • 54
    • 84864688815 scopus 로고    scopus 로고
    • Waking action of ursodeoxycholic acid (UDCA) involves histamine and GABAA receptor block
    • Yanovsky Y, Schubring SR, Yao Q, Zhao Y, Li S, May A, et al. (2012b). Waking action of ursodeoxycholic acid (UDCA) involves histamine and GABAA receptor block. PLoS ONE 7: e42512.
    • (2012) PLoS ONE , vol.7
    • Yanovsky, Y.1    Schubring, S.R.2    Yao, Q.3    Zhao, Y.4    Li, S.5    May, A.6
  • 56
    • 84866406441 scopus 로고    scopus 로고
    • GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness
    • Zecharia AY, Yu X, Gotz T, Ye Z, Carr DR, Wulff P, et al. (2012). GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness. J Neurosci 19: 13062-13075.
    • (2012) J Neurosci , vol.19 , pp. 13062-13075
    • Zecharia, A.Y.1    Yu, X.2    Gotz, T.3    Ye, Z.4    Carr, D.R.5    Wulff, P.6
  • 57
    • 45849116501 scopus 로고    scopus 로고
    • Conservation of sleep: Insights from non-mammalian model systems
    • Zimmerman JE, Naidoo N, Raizen DM, Pack AI, (2008). Conservation of sleep: insights from non-mammalian model systems. Trends Neurosci 31: 371-376.
    • (2008) Trends Neurosci , vol.31 , pp. 371-376
    • Zimmerman, J.E.1    Naidoo, N.2    Raizen, D.M.3    Pack, A.I.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.