Anatomical, physiological, and pharmacological characteristics of histidine decarboxylase knock-out mice: Evidence for the role of brain histamine in behavioral and sleep-wake control

Journal of Neuroscience

Volumn 22, Issue 17, 2002, Pages 7695-7711

  Parmentier, Régis ^a   Ohtsu, Hiroshi ^b   Djebbara Hannas, Zahia ^a   Valatx, Jean Louis ^a   Watanabe, Takehiko ^b   Lin, Jian Sheng ^a  

^a UNIVERSITÉ LYON 1   (France)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Arousal; Behavioral challenge; Cortical activation; Cortical EEG; Histamine; Histaminergic neurons; Histidine decarboxylase knock out mice; Sleep wake cycle; Wakefulness

Indexed keywords

ALPHA FLUOROMETHYLHISTIDINE; CIPROXIFAN; HISTAMINE; HISTIDINE DECARBOXYLASE;

ANIMAL EXPERIMENT; AROUSAL; ARTICLE; COGNITION; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ENVIRONMENTAL FACTOR; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; KNOCKOUT MOUSE; LATENT PERIOD; LIGHT; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SLEEP WAKING CYCLE; SOMNOLENCE;

EID: 0036759585     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-17-07695.2002     Document Type: Article

References (78)

1. Airaksinen MS, Panula P (1988) The histaminergic system in the guinea pig central nervous system: An immunocytochemical mapping study using an antiserum against histamine. J Comp Neurol 273:163-186.
2. Airaksinen MS, Alanen S, Szabat E, Visser TJ, Panula P (1992) Multiple neurotransmitters in the tuberomammillary nucleus: Comparison of rat, mouse, and guinea pig. J Comp Neurol 323:103-116.
3. Bland BH (1986) The physiology and pharmacology of hippocampal formation theta rhythms. Prog Neurobiol 26:1-54.
4. Borbély AA, Achermann P (2000) Sleep homeostasis and models of sleep regulation. In: Principles and Practice of Sleep Medicine (Kryger MH, Roth T, Dement WC, eds), pp 377-390. Philadelphia: Saunders.
5. Bouthenet ML, Ruat M, Sales N, Garbarg M, Schwartz JC (1988) A detailed mapping of histamine H1-receptors in guinea-pig central nervous system established by autoradiography with [125I]iodobolpyramine. Neuroscience 26:553-600.
6. Boutrel B, Franc B, Hen R, Hamon M, Adrien J (1999) Key role of 5-HT1B receptors in the regulation of paradoxical sleep as evidenced in 5-HT1B knock-out mice. J Neurosci 19:3204-3212.
7. Brown RE, Stevens DR, Haas HL (2001) The physiology of brain histamine. Prog Neurobiol 63:637-672.
8. Buzsaki G, Bickford RG, Ponomareff G, Thal LJ, Mandel R, Gage FH (1988) Nucleus basalis and thalamic control of neocortical activity in the freely moving rat. J Neurosci 8:4007-4026.
9. Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C, Richardson JA, Williams SC, Xiong Y, Kisanuki Y, Fitch TE, Nakazato M, Hammer RE, Saper CB, Yanagisawa M (1999) Narcolepsy in orexin knock-out mice: Molecular genetics of sleep regulation. Cell 98:437-451.
10. de Lecea L, Kilduff TS, Peyron C, Gao X, Foye PE, Danielson PE, Fukuhara C, Battenberg EL, Gautvik VT, Bartlett FS, Frankel WN, van den Pol AN, Bloom FE, Gautvik KM, Sutcliffe JG (1998) The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA 95:322-327.
11. Denoyer M, Sallanon M, Buda C, Kitahama K, Jouvet M (1991) Neurotoxic lesion of the mesencephalic reticular formation and/or the posterior hypothalamus does not alter waking in the rat. Brain Res 539:287-303.
12. Douglas WW (1985) Histamine and 5-hydroxytryptamine (serotonin) and their antagonists. In: The Pharmacological Basis of Therapeutics (Gilman AG, Goodman LS, Rall TW, Murad F, eds), pp 605-638. New York: Macmillan.
13. Eriksson KS, Sergeeva O, Brown RE, Haas HL (2001) Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus. J Neurosci 21:9273-9279.
14. Franken P, Malafosse A, Tafti M (1998) Genetic variation in EEG activity during sleep in inbred mice. Am J Physiol 275:1127-1137.
15. Franken P, Malafosse A, Tafti M (1999) Genetic determinants of sleep regulation in inbred mice. Sleep 22:155-169.
16. Franklin KB, Paxinos G (1996) The Mouse Brain in Stereotaxic Coordinates. San Diego: Academic.
17. Garbarg M, Barbin G, Rodergas E, Schwartz JC (1980) Inhibition of histamine synthesis in brain by alpha-fluoromethvlhistidine, a new irreversible inhibitor: In vitro and in vivo studies. J Neurochem 35:1045-1052.
18. Haas HL (1992) Electrophysiology of histamine-receptors. In: The Histamine Receptors (Schwartz JC, Haas HL, eds), pp 161-178. New York: Wiley-Liss.
19. Hara J, Beuckmann CT, Nambu T, Willie JT, Chemelli RM, Sinton CM, Sugiyama F, Yagami K, Goto K, Yanagisawa M, Sakurai T (2001) Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron 30:345-354.
20. Huang ZL, Qu WM, Li WD, Mochizuki T, Eguchi N, Watanabe T, Urade Y, Hayaishi O (2001) Arousal effect of orexin A depends on activation of the histaminergic system. Proc Natl Acad Sci USA 98:9965-9970.
21. Huber R, Deboer T, Tobler I (2000) Effects of sleep deprivation on sleep and sleep EEG in three mouse strains: Empirical data and simulations. Brain Res 857:8-19.
22. Inagaki N, Yamatodani A, Ando-Yamamoto M, Tohyama M, Watanabe T, Wada H (1988) Organization of histaminergic fibers in rat brain. J Comp Neurol 273:283-300.
23. Jones BE (2000) Basic mechanisms of sleep-wake states. In: Principles and Practice of Sleep Medicine (Kryger MH, Roth T, Dement WC, eds), pp 134-154. Philadelphia: Saunders.
24. Jouvet M (1972) The role of monoamines and acetylcholine containing neurons in the regulation of the sleep-waking cycle. Ergebn Physiol 64:166-307.
25. Kirk IJ, Oddie SD, Konopacki J, Bland BH (1996) Evidence for differential control of posterior hypothalamic, supramammillary, and medial mammillary theta-related cellular discharge by ascending and descending pathways. J Neurosci 16:5547-5554.
26. Kiyono S, Seo M, Shibagaki M, Watanabe T, Maeyama K, Wada H (1984) Effects of α-fluoromethylhistidine on sleep-waking parameters in rats. Physiol Behav 34:615-617.
27. Kollonitsch J, Perkins LM, Patchett AA, Doldouras GA, Marburg S, Duggan DE, Maycock AL, Aster SD (1978) Selective inhibitors of biosynthesis of aminergic neurotransmitters. Nature 274:906-908.
28. Ligneau X, Lin JS, Vanni-Mercier G, Jouvet M, Muir JL, Ganellin CR, Stark H, Elz S, Schunack W, Schwartz J (1998) Neurochemical and behavioral effects of ciproxifan, a potent histamine H3-receptor antagonist. J Pharmacol Exp Ther 287:658-666.
29. Lin JS (2000) Brain structures and mechanisms involved in the control of cortical activation and wakefulness, with emphasis on the posterior hypothalamus and histaminergic neurons. Sleep Med Rev 4:471-503.
30. Lin JS, Luppi PH, Salvert D, Sakai K, Jouvet M (1986a) Histamine-containing neurons in the cat hypothalamus. C R Acad Sci (III) 303:371-376.
31. Lin JS, Sakai K, Jouvet M (1986b) Role of hypothalamic histaminergic systems in the regulation of the states of vigilance in the cat. C R Acad Sci 303:469-474.
32. Lin JS, Sakai K, Jouvet M (1988) Evidence for histaminergic arousal mechanisms in the hypothalamus of cat. Neuropharmacology 27:111-122.
33. Lin JS, Sakai K, Vanni-Mercier G, Jouvet M (1989) A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscimol in freely moving cats. Brain Res 479:225-240.
34. Lin JS, Kitahama K, Fort P, Panula P, Denney RM, Jouvet M (1993) Histaminergic system in the posterior hypothalamus in the cat with reference to type B monoamine oxidase. J Comp Neurol 330:405-420.
35. Lin JS, Hou Y, Sakai K, Jouvet M (1996) Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat. J Neurosci 16:1523-1537.
36. Lin JS, Vanni-Mercier G, Parmentier R (2001) Histaminergic neurons and sleep-wake regulation. In: Histamine Research in the New Millennium (Watanabe T, Timmerman H, Yanai K, eds), pp 125-135. Amsterdam: Elsevier.
37. Lin JS, Parmentier R, Valatx JL, Watanabe T (2002) Cortical EEG and sleep-wake cycle in histamine H1-receptor knock-out mice. Soc Neurosci Abstr 28:XXX.
38. Lin L, Faraco J, Li R, Kadotani H, Rogers W, Lin X, Qiu X, de Jong PJ, Nishino S, Mignot E (1999) The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 98:365-376.
39. Maeyama K, Watanabe T, Taguchi Y, Yamatodani A, Wada H (1982) Effect of alpha-fluoromethylhistidine, a suicide inhibitor of histidine decarboxylase, on histamine levels in mouse tissues. Biochem Pharmacol 31:2367-2370.
40. Marcus JN, Aschkenasi CJ, Lee CE, Chemelli RM, Saper CB, Yanagisawa M, Elmquist JK (2001) Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol 435:6-25.
41. McCormick DA (1992) Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity. Prog Neurobiol 39:337-388.
42. Mochizuki T, Yamatodani A, Okakura K, Horii A, Inagaki N, Wada H (1992) Circadian rhythm of histamine release from the hypothalamus of freely moving rats. Physiol Behav 51:391-394.
43. Monti JM, D'Angeto L, Jantos H, Pazos S (1988) Effects of α-fluoromethylhistidine on sleep and wakefulness in the rat. J Neural Transm 72:141-145.
44. Monti JM, Jantos H, Boussard M, Altier H, Orellana C, Olivera S (1991) Effects of selective activation or blockade of the histamine H3 receptor on sleep and wakefulness. Eur J Pharmacol 205:283-287.
45. Moruzzi G (1972) The sleep-waking cycle. Ergeb Physiol 64:1-165.
46. Moruzzi G, Magoun HW (1949) Brainstem reticular formation and activation of the EEG. Electroencephalogr Clin Neurophysiol 1:455-473.
47. Nagy A, Rossant J, Nagy R, Abramow-Newerly W, Roder JC (1993) Derivation of completely cell culture-derived mice from early-passage embrvonic stem cells. Proc Natl Acad Sci USA 90:8424-8428.
48. Nicholson AN, Stone BM (1986) Antihistamines: Impaired performance and the tendency to sleep. Eur J Clin Pharmacol 30:27-32.
49. Nishino S, Fujiki N, Ripley B, Sakurai E, Kato M, Watanabe T, Mignot E, Yanai K (2001) Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptic dogs. Neurosci Lett 313:125-128.
50. Ohtsu H, Tanaka S, Terui T, Hori Y, Makabe-Kobayashi Y, Pejler G, Tchougounova E, Hellman L, Gertsenstein M, Hirasawa N, Sakurai E, Buzas E, Kovacs P, Csaba G, Kittel A, Okada M, Hara M, Mar L, Numayama-Tsuruta K, Ishigaki-Suzuki S, Ohuchi K, Ichikawa A, Falus A, Watanabe T, Nagy A (2001) Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett 502:53-56.
51. Orr E, Quay WB (1975) Hypothalamic 24-hour rhythms in histamine, histidine decarboxylase and histamine-N-methyltransferase. Endocrinology 96:941-945.
52. Panula P, Yang HY, Costa E (1984) Histamine-containing neurons in the rat hypothalamus. Proc Natl Acad Sci USA 81:2572-2576.
53. Panula P, Häppolä O, Airaksinen S, Auvinen S, Virkamäki A (1988) Carbodiimide as a tissue fixative in histamine immunohistochemistry and its application in developmental neurobiology. J Histochem Cytochem 36:259-269.
54. Panula P, Pirvola U, Auvinen S, Airaksinen MS (1989) Histamineimmunoreactive nerve fibers in the rat brain. Neuroscience 28:585-610.
55. Peyron C, Tighe DK, van den Pol AN, de Lecea L, Heller HC, Sutcliffe JG, Kilduff TS (1998) Neurons containing hypocretin (orexin) project to multiple neuronal systems. J Neurosci 18:9996-10015.
56. Sakai K, Salvert D, Kimura H, Maeda T, Jouvet M (1983) Ascending and descending projections of caudal hypothalamic neurons stained by serotoine immunohistochemistry after administration of 5-hydroxytriptophan in the cat. C R Acad Sci 296:1013-1018.
57. Sakai K, El Mansari M, Lin JS, Zhang JG, Vanni-Mercier G (1990) The posterior hypothalamus in the regulation of wakefulness and paradoxical sleep. In: The Diphencephalon and Sleep (Mancia M, Marini G, eds), pp 171-198. New York: Raven.
58. Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H, Williams SC, Richardson JA, Kozlowski GP, Wilson S, Arch JR, Buckingham RE, Haynes AC, Carr SA, Annan RS, McNulty DE, Liu WS, Terrett JA, Elshourbagy NA, Bergsma DJ, Yanagisawa M (1998) Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92:573-585.
59. Sallanon M, Sakai K, Buda C, Puymartin M, Jouvet M (1988) Increase of paradoxical sleep induced by microinjections of ibotenic acid into the ventrolateral part of the posterior hypothalamus in the cat. Arch Ital Biol 126:87-97.
60. Schwartz JC, Arrang JM, Garbarg M, Pollard H, Ruat M (1991) Histaminergic transmission in the mammalian brain. Physiol Rev 71:1-51.
61. Steinbusch HWM, Mulder AH (1984) Immunohistochemical localization of histamine in neurons and mast cells in the rat brain. In: Handbook of Chemical Neuroanatomy (Björklund A, Hökfelt T, and Kuhar MJ, eds), pp 126-140. Amsterdam: Elsevier.
62. Steininger TL, Alam MN, Gong H, Szymusiak R, McGinty D (1999) Sleep-waking discharge of neurons in the posterior lateral hypothalamus of the albino rat. Brain Res 840:138-147.
63. Steriade M (1991) Alertness, quiet sleep, dreaming. In: Cerebral Cortex, Vol 9 (Peters A, ed), pp 279-357, New York: Plenum.
64. Steriade M, Buzsaki G (1990) Parallel activation of thalamic and cortical neurons by brainstem and basal forebrain cholinergic system. In: Brain Cholinergic Systems (Steriade M, Biesold D, eds), pp 3-64, Oxford: Oxford UP.
65. Steriade M, McCarley RW (1990) Brainstem Control of Wakefulness and Sleep. New York: Plenum.
66. Tobler I (2000) Phylogeny of sleep regulation. In: Principles and Practice of Sleep Medicine (Kryger MH, Roth T, Dement WC, eds), pp 72-81. Philadelphia: Saunders.
67. Tobler I, Borbély AA (1986) Sleep EEG in the rat as a function of prior waking. Electroencephalogr Clin Neurophysiol 64:74-76.
68. Valatx JL (1971) Enregistrement chronique des activités électriques cérébrales, musculaires et oculaires chez la souris. C R Seances Soc Biol Fil 165:112-115.
69. Valatx JL, Bugat R (1974) Facteurs génétiques dans le determinisme du cycle veille-sommeil chez la souris. Brain Res 69:315-330.
70. Vanderwolf CH (1992) The electrocorticogram in relation to physiology and behavior: A new analysis. Electroencephalogr Clin Neurophysiol 82:165-175.
71. Vanderwolf CH, Stewart DJ (1988) Thalamic control of neocortical activation: A critical reevaluation. Brain Res Bull 20:529-538.
72. Vanni-Mercier G, Sakai K, Jouvet M (1984) Specific neurons for wakefulness in the posterior hypothalamus in the cat. C R Acad Sci III 298:195-200.
73. Vertes RP (1981) An analysis of ascending brain stem systems involved in hippocampal synchronization and desynchronization. J Neurophysiol 46:1140-1159.
74. Villablanca J (1974) Role of the thalamus in sleep control: Sleep-wakefulness in chronic diencephalic and athalamic cats. In: Basic Sleep Mechanisms (Petre-Quadens O, Schlag JD, eds), pp. 51-78. New York: Academic.
75. Watanabe T, Taguchi Y, Shiosaka S, Tanaka J, Kubota H, Terano Y, Tohyama M, Wada H (1984) Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decarboxylase as a marker. Brain Res 295:13-25.
76. Webster HH, Jones BE (1988) Neurotoxic lesions of the dorsolateral pontomesencephalic tegmentum-cholinergic cell area in the cat. II. Effects upon sleep-waking states. Brain Res 458:285-302.
77. Welsh DK, Richardson GS, Dement WC (1985) A circadian rhythm of hippocampal theta activity in the mouse. Physiol Behav 35:533-538.
78. Yanai K, Okamura N, Tagawa M, Itoh M, Watanabe T (1999) New findings in pharmacological effects induced by antihistamines: From PET studies to knock-out mice. Clin Exp Allergy [Suppl 3] 29:29-36.