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Volumn 9, Issue 2, 2013, Pages 130-147

The promises and challenges of the use of genomics in the prescription of exercise for hypertension: The 2013 update

Author keywords

Blood pressure; Genetics; Physical activity; Polymorphisms; Pre hypertension

Indexed keywords

ADENOSINE MONOPHOSPHATE DEAMINASE; ALDOSTERONE SYNTHASE; ALPHA ADDUCIN; APOLIPOPROTEIN E; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; C REACTIVE PROTEIN; CHOLINERGIC RECEPTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; FIBRINOGEN; GLUCOSE; GUANINE NUCLEOTIDE BINDING PROTEIN; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MICRORNA; NITRIC OXIDE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84881539881     PISSN: 15734021     EISSN: 18756506     Source Type: Journal    
DOI: 10.2174/15734021113099990010     Document Type: Article
Times cited : (27)

References (136)
  • 1
    • 83655196778 scopus 로고    scopus 로고
    • Mortality patterns in hypertension
    • Arima H, Barzi F, Chalmers J. Mortality patterns in hypertension. J Hypertens 2011; 29(1): S3-7.
    • (2011) J Hypertens , vol.29 , Issue.1
    • Arima, H.1    Barzi, F.2    Chalmers, J.3
  • 2
    • 84872091789 scopus 로고    scopus 로고
    • Heart disease and stroke statistics--2013 update: A report from the American Heart Association
    • Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics--2013 update: a report from the American Heart Association. Circulation 2013; 127(1): e6-e245.
    • (2013) Circulation , vol.127 , Issue.1
    • Go, A.S.1    Mozaffarian, D.2    Roger, V.L.3
  • 3
    • 0347423198 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    • Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003; 42(6): 1206-1252.
    • (2003) Hypertension , vol.42 , Issue.6 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3
  • 5
    • 79952444246 scopus 로고    scopus 로고
    • Forecasting the future of cardiovascular disease in the United States: A policy statement from the American Heart Association
    • Heidenreich PA, Trogdon JG, Khavjou OA, et al. Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation 2011; 123(8): 933-944.
    • (2011) Circulation , vol.123 , Issue.8 , pp. 933-944
    • Heidenreich, P.A.1    Trogdon, J.G.2    Khavjou, O.A.3
  • 6
    • 1542316760 scopus 로고    scopus 로고
    • American College of Sports Medicine position stand. Exercise and hypertension
    • Pescatello LS, Franklin BA, Fagard R, et al. American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc 2004; 36(3): 533-553.
    • (2004) Med Sci Sports Exerc , vol.36 , Issue.3 , pp. 533-553
    • Pescatello, L.S.1    Franklin, B.A.2    Fagard, R.3
  • 7
    • 31944451925 scopus 로고    scopus 로고
    • Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors
    • Cornelissen VA, Fagard RH. Effects of endurance training on blood pressure, blood pressure-regulating mechanisms, and cardiovascular risk factors. Hypertension 2005; 46(4): 667-675.
    • (2005) Hypertension , vol.46 , Issue.4 , pp. 667-675
    • Cornelissen, V.A.1    Fagard, R.H.2
  • 8
    • 33847083496 scopus 로고    scopus 로고
    • Effect of exercise on blood pressure control in hypertensive patients
    • Fagard RH, Cornelissen VA. Effect of exercise on blood pressure control in hypertensive patients. Eur J Cardiovasc Prev Rehabil 2007; 14(1):12-17.
    • (2007) Eur J Cardiovasc Prev Rehabil , vol.14 , Issue.1 , pp. 12-17
    • Fagard, R.H.1    Cornelissen, V.A.2
  • 9
    • 0035013148 scopus 로고    scopus 로고
    • Exercise characteristics and the blood pressure response to dynamic physical training
    • discussion S493-4
    • Fagard RH. Exercise characteristics and the blood pressure response to dynamic physical training. Med Sci Sports Exerc 2001; 33(6 Suppl): S484-92; discussion S493-4.
    • (2001) Med Sci Sports Exerc , vol.33 , Issue.6 SUPPL.
    • Fagard, R.H.1
  • 10
    • 0035032795 scopus 로고    scopus 로고
    • Aerobic exercise and resting blood pressure: A meta-analytic review of randomized, controlled trials
    • Kelley GA, Kelley KA, Tran ZV. Aerobic exercise and resting blood pressure: a meta-analytic review of randomized, controlled trials. Prev Cardiol 2001; 4(2): 73-80.
    • (2001) Prev Cardiol , vol.4 , Issue.2 , pp. 73-80
    • Kelley, G.A.1    Kelley, K.A.2    Tran, Z.V.3
  • 11
    • 0037006994 scopus 로고    scopus 로고
    • Effect of aerobic exercise on blood pressure: A meta-analysis of randomized, controlled trials
    • Whelton SP, Chin A, Xin X, He J. Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials. Ann Intern Med 2002; 136(7): 493-503.
    • (2002) Ann Intern Med , vol.136 , Issue.7 , pp. 493-503
    • Whelton, S.P.1    Chin, A.2    Xin, X.3    He, J.4
  • 12
    • 29244466110 scopus 로고    scopus 로고
    • Effects of exercise, diet and their combination on blood pressure
    • Fagard RH. Effects of exercise, diet and their combination on blood pressure. J Hum Hypertens 2005; 19(3): S20-4.
    • (2005) J Hum Hypertens , vol.19 , Issue.3
    • Fagard, R.H.1
  • 13
    • 33747036950 scopus 로고    scopus 로고
    • Exercise is good for your blood pressure: Effects of endurance training and resistance training
    • Fagard RH. Exercise is good for your blood pressure: effects of endurance training and resistance training. Clin Exp Pharmacol Physiol 2006; 33(9): 853-856.
    • (2006) Clin Exp Pharmacol Physiol , vol.33 , Issue.9 , pp. 853-856
    • Fagard, R.H.1
  • 14
    • 84875230859 scopus 로고    scopus 로고
    • Endurance exercise beneficially affects ambulatory blood pressure: A systematic review and meta-analysis
    • Cornelissen VA, Buys R, Smart NA. Endurance exercise beneficially affects ambulatory blood pressure: a systematic review and meta-analysis. J Hypertens 2013; 31(4): 639-648.
    • (2013) J Hypertens , vol.31 , Issue.4 , pp. 639-648
    • Cornelissen, V.A.1    Buys, R.2    Smart, N.A.3
  • 15
    • 0028790538 scopus 로고
    • Does exercise training play a role in the treatment of essential hypertension?
    • Hagberg JM, Brown MD. Does exercise training play a role in the treatment of essential hypertension? J Cardiovasc Risk 1995; 2(4): 296-302.
    • (1995) J Cardiovasc Risk , vol.2 , Issue.4 , pp. 296-302
    • Hagberg, J.M.1    Brown, M.D.2
  • 16
    • 0033830588 scopus 로고    scopus 로고
    • The role of exercise training in the treatment of hypertension: An update
    • Hagberg JM, Park JJ, Brown MD. The role of exercise training in the treatment of hypertension: an update. Sports Med 2000; 30(3): 193-206.
    • (2000) Sports Med , vol.30 , Issue.3 , pp. 193-206
    • Hagberg, J.M.1    Park, J.J.2    Brown, M.D.3
  • 17
    • 0034755307 scopus 로고    scopus 로고
    • The aftereffects of dynamic exercise on ambulatory blood pressure
    • Pescatello LS, Kulikowich JM. The aftereffects of dynamic exercise on ambulatory blood pressure. Med Sci Sports Exerc 2001; 33(11):1855-1861.
    • (2001) Med Sci Sports Exerc , vol.33 , Issue.11 , pp. 1855-1861
    • Pescatello, L.S.1    Kulikowich, J.M.2
  • 18
    • 0035003124 scopus 로고    scopus 로고
    • Individual differences in response to regular physical activity
    • discussion S452-3
    • Bouchard C, Rankinen T. Individual differences in response to regular physical activity. Med Sci Sports Exerc 2001; 33(6): S446-51; discussion S452-3.
    • (2001) Med Sci Sports Exerc , vol.33 , Issue.6 , pp. 446-451
    • Bouchard, C.1    Rankinen, T.2
  • 19
    • 0025827447 scopus 로고
    • What is the dose-response relationship between exercise training and blood pressure?
    • Jennings GL, Deakin G, Korner P, Meredith I, Kingwell B, Nelson L. What is the dose-response relationship between exercise training and blood pressure? Ann Med 1991; 23(3): 313-318.
    • (1991) Ann Med , vol.23 , Issue.3 , pp. 313-318
    • Jennings, G.L.1    Deakin, G.2    Korner, P.3    Meredith, I.4    Kingwell, B.5    Nelson, L.6
  • 20
    • 0025027865 scopus 로고
    • Time-course of the antihypertensive and autonomic effects of regular endurance exercise in human subjects
    • Meredith IT, Jennings GL, Esler MD, et al. Time-course of the antihypertensive and autonomic effects of regular endurance exercise in human subjects. J Hypertens 1990; 8(9): 859-866.
    • (1990) J Hypertens , vol.8 , Issue.9 , pp. 859-866
    • Meredith, I.T.1    Jennings, G.L.2    Esler, M.D.3
  • 21
    • 33745910562 scopus 로고    scopus 로고
    • Rapid onset and offset of circulatory adaptations to exercise training in men
    • Murray A, Delaney T, Bell C. Rapid onset and offset of circulatory adaptations to exercise training in men. J Hum Hypertens 2006; 20(3): 193-200.
    • (2006) J Hum Hypertens , vol.20 , Issue.3 , pp. 193-200
    • Murray, A.1    Delaney, T.2    Bell, C.3
  • 22
    • 84966714974 scopus 로고    scopus 로고
    • Interactive Effects of Genetics and Acute Exercise and Exercise Training on Plasma Lipoprotein Lipid and Blood Pressure Phenotypes
    • In: Pescatello LS, Roth SM, editors. NY: Springer
    • Hagberg JM. Interactive Effects of Genetics and Acute Exercise and Exercise Training on Plasma Lipoprotein Lipid and Blood Pressure Phenotypes. In: Pescatello LS, Roth SM, editors. Exercise Genomics New York, NY: Springer; 2011. p. 129-156.
    • (2011) Exercise Genomics New York , pp. 129-156
    • Hagberg, J.M.1
  • 23
    • 77949724153 scopus 로고    scopus 로고
    • A comparison of the genetic and clinical profile of men that respond and do not respond to the immediate antihypertensive effects of aerobic exercise
    • Pescatello LS, Blanchard BE, Tsongalis GJ, et al. A comparison of the genetic and clinical profile of men that respond and do not respond to the immediate antihypertensive effects of aerobic exercise. Application of Clinical Genetics 2008; 1: 7-17.
    • (2008) Application of Clinical Genetics , vol.1 , pp. 7-17
    • Pescatello, L.S.1    Blanchard, B.E.2    Tsongalis, G.J.3
  • 24
    • 84861605130 scopus 로고    scopus 로고
    • Adverse metabolic response to regular exercise: Is it a rare or common occurrence?
    • Bouchard C, Blair SN, Church TS, et al. Adverse metabolic response to regular exercise: is it a rare or common occurrence? PLoS One 2012; 7(5): e37887.
    • (2012) PLoS One , vol.7 , Issue.5
    • Bouchard, C.1    Blair, S.N.2    Church, T.S.3
  • 25
    • 77949689149 scopus 로고    scopus 로고
    • The promises and challenges of the use of genomics in the prescription of exercise in hypertension
    • Pescatello LS. The promises and challenges of the use of genomics in the prescription of exercise in hypertension. Current Hypertension Reviews 2010; 6(1): 32-43.
    • (2010) Current Hypertension Reviews , vol.6 , Issue.1 , pp. 32-43
    • Pescatello, L.S.1
  • 27
    • 79960205680 scopus 로고    scopus 로고
    • Do genetic variations alter the effects of exercise training on cardiovascular disease and can we identify the candidate variants now or in the future?
    • Hagberg JM. Do genetic variations alter the effects of exercise training on cardiovascular disease and can we identify the candidate variants now or in the future? J Appl Physiol 2011; 111(3): 916-928.
    • (2011) J Appl Physiol , vol.111 , Issue.3 , pp. 916-928
    • Hagberg, J.M.1
  • 28
    • 20644468211 scopus 로고    scopus 로고
    • Recommendations for blood pressure measurement in humans: An AHA scientific statement from the Council on High Blood Pressure Research Professional and Public Education Subcommittee
    • Pickering TG, Hall JE, Appel LJ, et al. Recommendations for blood pressure measurement in humans: an AHA scientific statement from the Council on High Blood Pressure Research Professional and Public Education Subcommittee. J Clin Hypertens (Greenwich) 2005; 7(2): 102-109.
    • (2005) J Clin Hypertens (Greenwich) , vol.7 , Issue.2 , pp. 102-109
    • Pickering, T.G.1    Hall, J.E.2    Appel, L.J.3
  • 29
    • 84859836273 scopus 로고    scopus 로고
    • Correlates of endothelial function and the peak systolic blood pressure response to a graded maximal exercise test
    • Olson KM, Augeri AL, Seip RL, Tsongalis GJ, Thompson PD, Pescatello LS. Correlates of endothelial function and the peak systolic blood pressure response to a graded maximal exercise test. Atherosclerosis 2012; 222(1): 202-207.
    • (2012) Atherosclerosis , vol.222 , Issue.1 , pp. 202-207
    • Olson, K.M.1    Augeri, A.L.2    Seip, R.L.3    Tsongalis, G.J.4    Thompson, P.D.5    Pescatello, L.S.6
  • 30
    • 67349245498 scopus 로고    scopus 로고
    • The endothelial nitric oxide synthase-786 T>C polymorphism and the exercise-induced blood pressure and nitric oxide responses among men with elevated blood pressure
    • Augeri AL, Tsongalis GJ, Van Heest JL, Maresh CM, Thompson PD, Pescatello LS. The endothelial nitric oxide synthase-786 T>C polymorphism and the exercise-induced blood pressure and nitric oxide responses among men with elevated blood pressure. Atherosclerosis 2009; 204(2): e28-34.
    • (2009) Atherosclerosis , vol.204 , Issue.2
    • Augeri, A.L.1    Tsongalis, G.J.2    van Heest, J.L.3    Maresh, C.M.4    Thompson, P.D.5    Pescatello, L.S.6
  • 31
    • 77956361138 scopus 로고    scopus 로고
    • The additive blood pressure lowering effects of exercise intensity on post-exercise hypotension
    • Eicher JD, Maresh CM, Tsongalis GJ, Thompson PD, Pescatello LS. The additive blood pressure lowering effects of exercise intensity on post-exercise hypotension. Am Heart J 2010; 160(3): 513-520.
    • (2010) Am Heart J , vol.160 , Issue.3 , pp. 513-520
    • Eicher, J.D.1    Maresh, C.M.2    Tsongalis, G.J.3    Thompson, P.D.4    Pescatello, L.S.5
  • 32
    • 82455188353 scopus 로고    scopus 로고
    • The higher exercise intensity and the presence of allele I of ACE gene elicit a higher post-exercise blood pressure reduction and nitric oxide release in elderly women: An experimental study
    • Santana HA, Moreira SR, Neto WB, et al. The higher exercise intensity and the presence of allele I of ACE gene elicit a higher post-exercise blood pressure reduction and nitric oxide release in elderly women: an experimental study. BMC Cardiovasc Disord 2011; 11: 71-2261-11-71.
    • (2011) BMC Cardiovasc Disord , vol.11 , pp. 2261-7111
    • Santana, H.A.1    Moreira, S.R.2    Neto, W.B.3
  • 33
    • 78049349523 scopus 로고    scopus 로고
    • The influence of alpha-adducin gene polymorphism on response of blood pressure to exercise in patients with hypertension
    • Alioglu E, Ercan E, Tengiz I, et al. The influence of alpha-adducin gene polymorphism on response of blood pressure to exercise in patients with hypertension. Anadolu Kardiyol Derg 2010; 10(5): 400-404.
    • (2010) Anadolu Kardiyol Derg , vol.10 , Issue.5 , pp. 400-404
    • Alioglu, E.1    Ercan, E.2    Tengiz, I.3
  • 34
    • 0019381237 scopus 로고
    • Labile hypertension and jogging: New diagnostic tool or spurious discovery?
    • Fitzgerald W. Labile hypertension and jogging: new diagnostic tool or spurious discovery? Br Med J (Clin Res Ed) 1981; 282(6263): 542-544.
    • (1981) Br Med J (Clin Res Ed) , vol.282 , Issue.6263 , pp. 542-544
    • Fitzgerald, W.1
  • 35
    • 0035316056 scopus 로고    scopus 로고
    • Mechanisms and clinical implications of postexercise hypotension in humans
    • Halliwill JR. Mechanisms and clinical implications of postexercise hypotension in humans. Exerc Sport Sci Rev 2001; 29(2): 65-70.
    • (2001) Exerc Sport Sci Rev , vol.29 , Issue.2 , pp. 65-70
    • Halliwill, J.R.1
  • 36
    • 0028302352 scopus 로고
    • Wolffe Memorial Lecture. Health consequences of physical activity: Understanding and challenges regarding doseresponse
    • Haskell WL. J.B. Wolffe Memorial Lecture. Health consequences of physical activity: understanding and challenges regarding doseresponse. Med Sci Sports Exerc 1994; 26(6): 649-660.
    • (1994) Med Sci Sports Exerc , vol.26 , Issue.6 , pp. 649-660
    • Haskell, W.L.J.B.1
  • 39
    • 84865491160 scopus 로고    scopus 로고
    • Blood Pressure Responses to Acute and Chronic Exercise are Related in Prehypertensives
    • Liu S, Goodman J, Nolan R, Lacombe S, Thomas S. Blood Pressure Responses to Acute and Chronic Exercise are Related in Prehypertensives. Med Sci Sports Exerc 2012.
    • (2012) Med Sci Sports Exerc
    • Liu, S.1    Goodman, J.2    Nolan, R.3    Lacombe, S.4    Thomas, S.5
  • 40
    • 41549166043 scopus 로고    scopus 로고
    • Acute exercise increases systemic arterial compliance after 6-month exercise training in older women
    • Maeda S, Tanabe T, Otsuki T, Sugawara J, Ajisaka R, Matsuda M. Acute exercise increases systemic arterial compliance after 6-month exercise training in older women. Hypertens Res 2008; 31(2): 377-381.
    • (2008) Hypertens Res , vol.31 , Issue.2 , pp. 377-381
    • Maeda, S.1    Tanabe, T.2    Otsuki, T.3    Sugawara, J.4    Ajisaka, R.5    Matsuda, M.6
  • 41
    • 36248948949 scopus 로고    scopus 로고
    • Effect of acute and long-term aerobic exercise on arterial stiffness in the elderly
    • Tabara Y, Yuasa T, Oshiumi A, et al. Effect of acute and long-term aerobic exercise on arterial stiffness in the elderly. Hypertens Res 2007; 30(10): 895-902.
    • (2007) Hypertens Res , vol.30 , Issue.10 , pp. 895-902
    • Tabara, Y.1    Yuasa, T.2    Oshiumi, A.3
  • 42
    • 17744367051 scopus 로고    scopus 로고
    • The subacute effects of exercise: Concept, characteristics, and clinical implications
    • da Nobrega AC. The subacute effects of exercise: concept, characteristics, and clinical implications. Exerc Sport Sci Rev 2005; 33(2): 84-87.
    • (2005) Exerc Sport Sci Rev , vol.33 , Issue.2 , pp. 84-87
    • da Nobrega, A.C.1
  • 43
    • 84872079322 scopus 로고    scopus 로고
    • Association between postexercise hypotension and long-term training-induced blood pressure reduction: A pilot study
    • Hecksteden A, Grutters T, Meyer T. Association between postexercise hypotension and long-term training-induced blood pressure reduction: a pilot study. Clin J Sport Med 2013; 23(1): 58-63.
    • (2013) Clin J Sport Med , vol.23 , Issue.1 , pp. 58-63
    • Hecksteden, A.1    Grutters, T.2    Meyer, T.3
  • 44
    • 84872190804 scopus 로고    scopus 로고
    • Postexercise hypotension and sustained postexercise vasodilatation: What happens after we exercise?
    • Halliwill JR, Buck TM, Lacewell AN, Romero SA. Postexercise hypotension and sustained postexercise vasodilatation: what happens after we exercise? Exp Physiol 2013; 98(1): 7-18.
    • (2013) Exp Physiol , vol.98 , Issue.1 , pp. 7-18
    • Halliwill, J.R.1    Buck, T.M.2    Lacewell, A.N.3    Romero, S.A.4
  • 46
    • 78049337798 scopus 로고    scopus 로고
    • Effects of aerobic exercise on the blood pressure, oxidative stress and eNOS gene polymorphism in pre-hypertensive older people
    • Zago AS, Park JY, Fenty-Stewart N, Kokubun E, Brown MD. Effects of aerobic exercise on the blood pressure, oxidative stress and eNOS gene polymorphism in pre-hypertensive older people. Eur J Appl Physiol 2010; 110(4): 825-832.
    • (2010) Eur J Appl Physiol , vol.110 , Issue.4 , pp. 825-832
    • Zago, A.S.1    Park, J.Y.2    Fenty-Stewart, N.3    Kokubun, E.4    Brown, M.D.5
  • 47
    • 80053336010 scopus 로고    scopus 로고
    • Influence of eNOS gene polymorphism on cardiometabolic parameters in response to physical training in postmenopausal women
    • Esposti RD, Sponton CH, Malagrino PA, et al. Influence of eNOS gene polymorphism on cardiometabolic parameters in response to physical training in postmenopausal women. Braz J Med Biol Res 2011; 44(9): 855-863.
    • (2011) Braz J Med Biol Res , vol.44 , Issue.9 , pp. 855-863
    • Esposti, R.D.1    Sponton, C.H.2    Malagrino, P.A.3
  • 48
    • 78650738650 scopus 로고    scopus 로고
    • Effect of physical activity and t-786C polymorphism in blood pressure and blood flow in the elderly
    • Zago AS, Kokubun E, Fenty-Stewart N, et al. Effect of physical activity and t-786C polymorphism in blood pressure and blood flow in the elderly. Arq Bras Cardiol 2010; 95(4): 510-516.
    • (2010) Arq Bras Cardiol , vol.95 , Issue.4 , pp. 510-516
    • Zago, A.S.1    Kokubun, E.2    Fenty-Stewart, N.3
  • 49
    • 82455171766 scopus 로고    scopus 로고
    • Effect of exercise training on the cardiovascular and biochemical parameters in women with eNOS gene polymorphism
    • Rezende TM, Sponton CH, Malagrino PA, Bezerra MA, Penteado CF, Zanesco A. Effect of exercise training on the cardiovascular and biochemical parameters in women with eNOS gene polymorphism. Arch Physiol Biochem 2011; 117(5): 265-269.
    • (2011) Arch Physiol Biochem , vol.117 , Issue.5 , pp. 265-269
    • Rezende, T.M.1    Sponton, C.H.2    Malagrino, P.A.3    Bezerra, M.A.4    Penteado, C.F.5    Zanesco, A.6
  • 50
    • 0037187042 scopus 로고    scopus 로고
    • G protein beta 3 polymorphism and hemodynamic and body composition phenotypes in the HERITAGE Family Study
    • Rankinen T, Rice T, Leon AS, Skinner JS, Wilmore JH, Rao DC, et al. G protein beta 3 polymorphism and hemodynamic and body composition phenotypes in the HERITAGE Family Study. Physiol Genomics 2002; 8(2): 151-157.
    • (2002) Physiol Genomics , vol.8 , Issue.2 , pp. 151-157
    • Rankinen, T.1    Rice, T.2    Leon, A.S.3    Skinner, J.S.4    Wilmore, J.H.5    Rao, D.C.6
  • 51
    • 36448989264 scopus 로고    scopus 로고
    • Effect of endothelin 1 genotype on blood pressure is dependent on physical activity or fitness levels
    • Rankinen T, Church T, Rice T, et al. Effect of endothelin 1 genotype on blood pressure is dependent on physical activity or fitness levels. Hypertension 2007; 50(6):1120-1125.
    • (2007) Hypertension , vol.50 , Issue.6 , pp. 1120-1125
    • Rankinen, T.1    Church, T.2    Rice, T.3
  • 52
    • 0033679202 scopus 로고    scopus 로고
    • NOS3 Glu298Asp genotype and blood pressure response to endurance training: The HERITAGE family study
    • Rankinen T, Rice T, Perusse L, et al. NOS3 Glu298Asp genotype and blood pressure response to endurance training: the HERITAGE family study. Hypertension 2000; 36(5): 885-889.
    • (2000) Hypertension , vol.36 , Issue.5 , pp. 885-889
    • Rankinen, T.1    Rice, T.2    Perusse, L.3
  • 53
    • 0033866536 scopus 로고    scopus 로고
    • AGT M235T and ACE ID polymorphisms and exercise blood pressure in the HERITAGE Family Study
    • Rankinen T, Gagnon J, Perusse L, et al. AGT M235T and ACE ID polymorphisms and exercise blood pressure in the HERITAGE Family Study. Am J Physiol Heart Circ Physiol 2000; 279(1): H368-74.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279 , Issue.1
    • Rankinen, T.1    Gagnon, J.2    Perusse, L.3
  • 54
    • 0036626845 scopus 로고    scopus 로고
    • Genetics and blood pressure response to exercise, and its interactions with adiposity
    • Summer
    • Rankinen T, Bouchard C. Genetics and blood pressure response to exercise, and its interactions with adiposity. Prev Cardiol 2002 Summer; 5(3): 138-144.
    • (2002) Prev Cardiol , vol.5 , Issue.3 , pp. 138-144
    • Rankinen, T.1    Bouchard, C.2
  • 55
    • 52449100587 scopus 로고    scopus 로고
    • Trends in obesity and abdominal obesity among hypertensive and nonhypertensive adults in the United States
    • Ford ES, Zhao G, Li C, Pearson WS, Mokdad AH. Trends in obesity and abdominal obesity among hypertensive and nonhypertensive adults in the United States. Am J Hypertens 2008; 21(10): 1124-1128.
    • (2008) Am J Hypertens , vol.21 , Issue.10 , pp. 1124-1128
    • Ford, E.S.1    Zhao, G.2    Li, C.3    Pearson, W.S.4    Mokdad, A.H.5
  • 56
    • 39549091283 scopus 로고    scopus 로고
    • Deteriorating dietary habits among adults with hypertension: DASH dietary accordance, NHANES 1988-1994 and 1999-2004
    • Mellen PB, Gao SK, Vitolins MZ, Goff DC, Jr. Deteriorating dietary habits among adults with hypertension: DASH dietary accordance, NHANES 1988-1994 and 1999-2004. Arch Intern Med 2008; 168(3): 308-314.
    • (2008) Arch Intern Med , vol.168 , Issue.3 , pp. 308-314
    • Mellen, P.B.1    Gao, S.K.2    Vitolins, M.Z.3    Goff Jr., D.C.4
  • 57
    • 77955981998 scopus 로고    scopus 로고
    • Comparing physical activity patterns of hypertensive and nonhypertensive US adults
    • Churilla JR, Ford ES. Comparing physical activity patterns of hypertensive and nonhypertensive US adults. Am J Hypertens 2010; 23(9): 987-993.
    • (2010) Am J Hypertens , vol.23 , Issue.9 , pp. 987-993
    • Churilla, J.R.1    Ford, E.S.2
  • 58
    • 77949701424 scopus 로고    scopus 로고
    • The GNAS 393 T>C polymorphism and the blood pressure response immediately following aerobic exercise among men with elevated blood pressure
    • Pescatello LS, Blanchard BE, Tsongalis GJ, Maresh CM, Griffiths B, Thompson PD. The GNAS 393 T>C polymorphism and the blood pressure response immediately following aerobic exercise among men with elevated blood pressure. Vasc Dis Prev 2009(6): 56-64.
    • (2009) Vasc Dis Prev , Issue.6 , pp. 56-64
    • Pescatello, L.S.1    Blanchard, B.E.2    Tsongalis, G.J.3    Maresh, C.M.4    Griffiths, B.5    Thompson, P.D.6
  • 59
    • 34548488932 scopus 로고    scopus 로고
    • The alpha-adducin Gly460Trp polymorphism and the antihypertensive effects of exercise among men with high blood pressure
    • Pescatello LS, Blanchard BE, Tsongalis GJ, Maresh CM, O'Connell A, Thompson PD. The alpha-adducin Gly460Trp polymorphism and the antihypertensive effects of exercise among men with high blood pressure. Clin Sci (Lond) 2007; 113(5): 251-258.
    • (2007) Clin Sci (Lond) , vol.113 , Issue.5 , pp. 251-258
    • Pescatello, L.S.1    Blanchard, B.E.2    Tsongalis, G.J.3    Maresh, C.M.4    O'Connell, A.5    Thompson, P.D.6
  • 60
    • 33745472715 scopus 로고    scopus 로고
    • RAAS polymorphisms alter the acute blood pressure response to aerobic exercise among men with hypertension
    • Blanchard BE, Tsongalis GJ, Guidry MA, LaBelle LA, Poulin M, Taylor AL, et al. RAAS polymorphisms alter the acute blood pressure response to aerobic exercise among men with hypertension. Eur J Appl Physiol 2006; 97(1): 26-33.
    • (2006) Eur J Appl Physiol , vol.97 , Issue.1 , pp. 26-33
    • Blanchard, B.E.1    Tsongalis, G.J.2    Guidry, M.A.3    LaBelle, L.A.4    Poulin, M.5    Taylor, A.L.6
  • 61
  • 62
    • 14644401770 scopus 로고    scopus 로고
    • Adducin polymorphism: Detection and impact on hypertension and related disorders
    • Bianchi G, Ferrari P, Staessen JA. Adducin polymorphism: detection and impact on hypertension and related disorders. Hypertension 2005; 45(3): 331-340.
    • (2005) Hypertension , vol.45 , Issue.3 , pp. 331-340
    • Bianchi, G.1    Ferrari, P.2    Staessen, J.A.3
  • 63
    • 0042738775 scopus 로고    scopus 로고
    • Angiotensin II AT2 receptor subtype: An uprising frontier in cardiovascular disease?
    • Volpe M, Musumeci B, De Paolis P, Savoia C, Morganti A. Angiotensin II AT2 receptor subtype: an uprising frontier in cardiovascular disease? J Hypertens 2003; 21(8): 1429-1443.
    • (2003) J Hypertens , vol.21 , Issue.8 , pp. 1429-1443
    • Volpe, M.1    Musumeci, B.2    de Paolis, P.3    Savoia, C.4    Morganti, A.5
  • 64
    • 0034897607 scopus 로고    scopus 로고
    • Effects of three candidate genes on prevalence and incidence of hypertension in a Caucasian population
    • Staessen JA, Wang JG, Brand E, et al. Effects of three candidate genes on prevalence and incidence of hypertension in a Caucasian population. J Hypertens 2001; 19(8): 1349-1358.
    • (2001) J Hypertens , vol.19 , Issue.8 , pp. 1349-1358
    • Staessen, J.A.1    Wang, J.G.2    Brand, E.3
  • 65
    • 0025980368 scopus 로고
    • Insulin resistance, hyperinsulinemia, hypertriglyceridemia, and hypertension. Parallels between human disease and rodent models
    • Reaven GM. Insulin resistance, hyperinsulinemia, hypertriglyceridemia, and hypertension. Parallels between human disease and rodent models. Diabetes Care 1991; 14(3): 195-202.
    • (1991) Diabetes Care , vol.14 , Issue.3 , pp. 195-202
    • Reaven, G.M.1
  • 66
    • 0036311315 scopus 로고    scopus 로고
    • Enhanced endothelin activity prevents vasodilation to insulin in insulin resistance
    • Miller AW, Tulbert C, Puskar M, Busija DW. Enhanced endothelin activity prevents vasodilation to insulin in insulin resistance. Hypertension 2002; 40(1): 78-82.
    • (2002) Hypertension , vol.40 , Issue.1 , pp. 78-82
    • Miller, A.W.1    Tulbert, C.2    Puskar, M.3    Busija, D.W.4
  • 67
    • 33645978121 scopus 로고    scopus 로고
    • Metabolic syndrome--a new worldwide definition. A Consensus Statement from the International Diabetes Federation
    • Alberti KG, Zimmet P, Shaw J. Metabolic syndrome--a new worldwide definition. A Consensus Statement from the International Diabetes Federation. Diabet Med 2006; 23(5): 469-480.
    • (2006) Diabet Med , vol.23 , Issue.5 , pp. 469-480
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 69
    • 0035050699 scopus 로고    scopus 로고
    • Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR
    • Kren V, Qi N, Krenova D, et al. Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR. Hypertension 2001; 37(4): 1147-1152.
    • (2001) Hypertension , vol.37 , Issue.4 , pp. 1147-1152
    • Kren, V.1    Qi, N.2    Krenova, D.3
  • 70
    • 0035092295 scopus 로고    scopus 로고
    • Reciprocal consomic strains to evaluate y chromosome effects
    • Negrin CD, McBride MW, Carswell HV, et al. Reciprocal consomic strains to evaluate y chromosome effects. Hypertension 2001; 37(2 Part 2): 391-397.
    • (2001) Hypertension , vol.37 , Issue.2 PART 2 , pp. 391-397
    • Negrin, C.D.1    McBride, M.W.2    Carswell, H.V.3
  • 71
    • 0030831603 scopus 로고    scopus 로고
    • Contribution of nitric oxide to exercise-induced changes in healthy volunteers: Effects of acute exercise and long-term physical training
    • Poveda JJ, Riestra A, Salas E, et al. Contribution of nitric oxide to exercise-induced changes in healthy volunteers: effects of acute exercise and long-term physical training. Eur J Clin Invest 1997; 27(11): 967-971.
    • (1997) Eur J Clin Invest , vol.27 , Issue.11 , pp. 967-971
    • Poveda, J.J.1    Riestra, A.2    Salas, E.3
  • 73
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • Palmer RM, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988; 333(6174): 664-666.
    • (1988) Nature , vol.333 , Issue.6174 , pp. 664-666
    • Palmer, R.M.1    Ashton, D.S.2    Moncada, S.3
  • 74
    • 34249331338 scopus 로고    scopus 로고
    • Acute exercise-induced nitric oxide production contributes to upregulation of circulating endothelial progenitor cells in healthy subjects
    • Yang Z, Wang JM, Chen L, Luo CF, Tang AL, Tao J. Acute exercise-induced nitric oxide production contributes to upregulation of circulating endothelial progenitor cells in healthy subjects. J Hum Hypertens 2007; 21(6): 452-460.
    • (2007) J Hum Hypertens , vol.21 , Issue.6 , pp. 452-460
    • Yang, Z.1    Wang, J.M.2    Chen, L.3    Luo, C.F.4    Tang, A.L.5    Tao, J.6
  • 75
    • 33846636038 scopus 로고    scopus 로고
    • Nitric oxide, cardiovascular disease and physical exercise
    • Zago AS, Zanesco A. Nitric oxide, cardiovascular disease and physical exercise. Arq Bras Cardiol 2006; 87(6): e264-70.
    • (2006) Arq Bras Cardiol , vol.87 , Issue.6
    • Zago, A.S.1    Zanesco, A.2
  • 76
    • 84881508542 scopus 로고    scopus 로고
    • Exercise intensity modulates nitric oxide and blood pressure responses in hypertensive older women
    • Santana HA, Moreira SR, Asano RY, et al. Exercise intensity modulates nitric oxide and blood pressure responses in hypertensive older women. Aging Clin Exp Res 2013; 25(1): 43-48.
    • (2013) Aging Clin Exp Res , vol.25 , Issue.1 , pp. 43-48
    • Santana, H.A.1    Moreira, S.R.2    Asano, R.Y.3
  • 77
    • 0033554460 scopus 로고    scopus 로고
    • Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: Role of endotheliumderived nitric oxide
    • Higashi Y, Sasaki S, Kurisu S, et al. Regular aerobic exercise augments endothelium-dependent vascular relaxation in normotensive as well as hypertensive subjects: role of endotheliumderived nitric oxide. Circulation 1999; 100(11): 1194-1202.
    • (1999) Circulation , vol.100 , Issue.11 , pp. 1194-1202
    • Higashi, Y.1    Sasaki, S.2    Kurisu, S.3
  • 78
    • 21244460344 scopus 로고    scopus 로고
    • Low frequency regular exercise improves flow-mediated dilatation of subjects with mild hypertension
    • Moriguchi J, Itoh H, Harada S, et al. Low frequency regular exercise improves flow-mediated dilatation of subjects with mild hypertension. Hypertens Res 2005; 28(4): 315-321.
    • (2005) Hypertens Res , vol.28 , Issue.4 , pp. 315-321
    • Moriguchi, J.1    Itoh, H.2    Harada, S.3
  • 79
    • 0033535841 scopus 로고    scopus 로고
    • T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm
    • Jun 8
    • Nakayama M, Yasue H, Yoshimura M, et al. T-786-->C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. Circulation 1999 Jun 8;99(22):2864-2870.
    • (1999) Circulation , vol.99 , Issue.22 , pp. 2864-2870
    • Nakayama, M.1    Yasue, H.2    Yoshimura, M.3
  • 80
    • 0037372779 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase gene polymorphisms and risk of coronary artery disease
    • Colombo MG, Paradossi U, Andreassi MG, et al. Endothelial nitric oxide synthase gene polymorphisms and risk of coronary artery disease. Clin Chem 2003; 49(3): 389-395.
    • (2003) Clin Chem , vol.49 , Issue.3 , pp. 389-395
    • Colombo, M.G.1    Paradossi, U.2    Andreassi, M.G.3
  • 82
    • 33947118928 scopus 로고    scopus 로고
    • Anti-inflammatory effects of atorvastatin: Modulation by the T-786C polymorphism in the endothelial nitric oxide synthase gene
    • Souza-Costa DC, Sandrim VC, Lopes LF, Gerlach RF, Rego EM, Tanus-Santos JE. Anti-inflammatory effects of atorvastatin: modulation by the T-786C polymorphism in the endothelial nitric oxide synthase gene. Atherosclerosis 2007; 193(2): 438-444.
    • (2007) Atherosclerosis , vol.193 , Issue.2 , pp. 438-444
    • Souza-Costa, D.C.1    Sandrim, V.C.2    Lopes, L.F.3    Gerlach, R.F.4    Rego, E.M.5    Tanus-Santos, J.E.6
  • 83
    • 0036312651 scopus 로고    scopus 로고
    • Is exercise blood pressure a marker of vascular endothelial function?
    • Tzemos N, Lim PO, MacDonald TM. Is exercise blood pressure a marker of vascular endothelial function? QJM 2002; 95(7): 423-429.
    • (2002) QJM , vol.95 , Issue.7 , pp. 423-429
    • Tzemos, N.1    Lim, P.O.2    McDonald, T.M.3
  • 84
    • 0034332864 scopus 로고    scopus 로고
    • Exercise BP response in subjects with high-normal BP: Exaggerated blood pressure response to exercise and risk of future hypertension in subjects with high-normal blood pressure
    • Miyai N, Arita M, Morioka I, Miyashita K, Nishio I, Takeda S. Exercise BP response in subjects with high-normal BP: exaggerated blood pressure response to exercise and risk of future hypertension in subjects with high-normal blood pressure. J Am Coll Cardiol 2000; 36(5): 1626-1631.
    • (2000) J Am Coll Cardiol , vol.36 , Issue.5 , pp. 1626-1631
    • Miyai, N.1    Arita, M.2    Morioka, I.3    Miyashita, K.4    Nishio, I.5    Takeda, S.6
  • 86
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature 2009; 461(7265): 747-753.
    • (2009) Nature , vol.461 , Issue.7265 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3
  • 87
    • 84858702544 scopus 로고    scopus 로고
    • Hypercontrols in genotype-phenotype analysis reveal ancestral haplotypes associated with essential hypertension
    • Balam-Ortiz E, Esquivel-Villarreal A, Huerta-Hernandez D, et al. Hypercontrols in genotype-phenotype analysis reveal ancestral haplotypes associated with essential hypertension. Hypertension 2012; 59(4): 847-853.
    • (2012) Hypertension , vol.59 , Issue.4 , pp. 847-853
    • Balam-Ortiz, E.1    Esquivel-Villarreal, A.2    Huerta-Hernandez, D.3
  • 88
    • 84856405512 scopus 로고    scopus 로고
    • The mystery of missing heritability: Genetic interactions create phantom heritability
    • Zuk O, Hechter E, Sunyaev SR, Lander ES. The mystery of missing heritability: Genetic interactions create phantom heritability. Proc Natl Acad Sci U S A 2012; 109(4): 1193-1198.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.4 , pp. 1193-1198
    • Zuk, O.1    Hechter, E.2    Sunyaev, S.R.3    Lander, E.S.4
  • 90
    • 84860218599 scopus 로고    scopus 로고
    • Report of the national heart, lung, and blood institute working group on epigenetics and hypertension
    • Cowley AW, Jr, Nadeau JH, Baccarelli A, et al. Report of the national heart, lung, and blood institute working group on epigenetics and hypertension. Hypertension 2012; 59(5): 899-905.
    • (2012) Hypertension , vol.59 , Issue.5 , pp. 899-905
    • Cowley Jr., A.W.1    Nadeau, J.H.2    Baccarelli, A.3
  • 91
    • 79952805247 scopus 로고    scopus 로고
    • Cardiovascular epigenetics: Basic concepts and results from animal and human studies
    • Baccarelli A, Rienstra M, Benjamin EJ. Cardiovascular epigenetics: basic concepts and results from animal and human studies. Circ Cardiovasc Genet 2010; 3(6): 567-573.
    • (2010) Circ Cardiovasc Genet , vol.3 , Issue.6 , pp. 567-573
    • Baccarelli, A.1    Rienstra, M.2    Benjamin, E.J.3
  • 92
    • 80053375418 scopus 로고    scopus 로고
    • Overcoming barriers to progress in exercise genomics
    • Bouchard C. Overcoming barriers to progress in exercise genomics. Exerc Sport Sci Rev 2011; 39(4): 212-217.
    • (2011) Exerc Sport Sci Rev , vol.39 , Issue.4 , pp. 212-217
    • Bouchard, C.1
  • 93
    • 41949113710 scopus 로고    scopus 로고
    • Perspective on the future use of genomics in exercise prescription
    • Roth SM. Perspective on the future use of genomics in exercise prescription. J Appl Physiol 2008; 104(4): 1243-1245.
    • (2008) J Appl Physiol , vol.104 , Issue.4 , pp. 1243-1245
    • Roth, S.M.1
  • 94
    • 77950221218 scopus 로고    scopus 로고
    • Research in the exercise sciences: Where we are and where do we go from here--Part II
    • Baldwin KM, Haddad F. Research in the exercise sciences: where we are and where do we go from here--Part II. Exerc Sport Sci Rev 2010; 38(2): 42-50.
    • (2010) Exerc Sport Sci Rev , vol.38 , Issue.2 , pp. 42-50
    • Baldwin, K.M.1    Haddad, F.2
  • 95
    • 41949086285 scopus 로고    scopus 로고
    • Commentary on viewpoint: Perspective on the future use of genomics in exercise prescription
    • Pescatello LS. Commentary on viewpoint: Perspective on the future use of genomics in exercise prescription. J Appl Physiol 2008; 104(4):1247.
    • (2008) J Appl Physiol , vol.104 , Issue.4 , pp. 1247
    • Pescatello, L.S.1
  • 96
    • 84869457261 scopus 로고    scopus 로고
    • The expanding scope of DNA sequencing
    • Shendure J, Lieberman Aiden E. The expanding scope of DNA sequencing. Nat Biotechnol 2012; 30(11): 1084-1094.
    • (2012) Nat Biotechnol , vol.30 , Issue.11 , pp. 1084-1094
    • Shendure, J.1    Lieberman Aiden, E.2
  • 97
    • 67650093999 scopus 로고    scopus 로고
    • Myostatin and follistatin polymorphisms interact with muscle phenotypes and ethnicity
    • Kostek MA, Angelopoulos TJ, Clarkson PM, et al. Myostatin and follistatin polymorphisms interact with muscle phenotypes and ethnicity. Med Sci Sports Exerc 2009; 41(5): 1063-1071.
    • (2009) Med Sci Sports Exerc , vol.41 , Issue.5 , pp. 1063-1071
    • Kostek, M.A.1    Angelopoulos, T.J.2    Clarkson, P.M.3
  • 98
    • 21644474657 scopus 로고    scopus 로고
    • ACTN3 genotype is associated with increases in muscle strength in response to resistance training in women
    • Clarkson PM, Devaney JM, Gordish-Dressman H, et al. ACTN3 genotype is associated with increases in muscle strength in response to resistance training in women. J Appl Physiol 2005; 99(1): 154-163.
    • (2005) J Appl Physiol , vol.99 , Issue.1 , pp. 154-163
    • Clarkson, P.M.1    Devaney, J.M.2    Gordish-Dressman, H.3
  • 99
    • 84861510163 scopus 로고    scopus 로고
    • Genomic Association Analysis Identifies Multiple Loci Influencing Antihypertensive Response to an Angiotensin II Receptor Blocker
    • Turner ST, Bailey KR, Schwartz GL, Chapman AB, Chai HS, Boerwinkle E. Genomic Association Analysis Identifies Multiple Loci Influencing Antihypertensive Response to an Angiotensin II Receptor Blocker. Hypertension 2012; 59(6): 1204-1211.
    • (2012) Hypertension , vol.59 , Issue.6 , pp. 1204-1211
    • Turner, S.T.1    Bailey, K.R.2    Schwartz, G.L.3    Chapman, A.B.4    Chai, H.S.5    Boerwinkle, E.6
  • 100
    • 73849141493 scopus 로고    scopus 로고
    • Genotype-phenotype analysis of angiotensinogen polymorphisms and essential hypertension: The importance of haplotypes
    • Watkins WS, Hunt SC, Williams GH, et al. Genotype-phenotype analysis of angiotensinogen polymorphisms and essential hypertension: the importance of haplotypes. J Hypertens 2010; 28(1): 65-75.
    • (2010) J Hypertens , vol.28 , Issue.1 , pp. 65-75
    • Watkins, W.S.1    Hunt, S.C.2    Williams, G.H.3
  • 102
    • 79956077552 scopus 로고    scopus 로고
    • Genomic predictors of the maximal O uptake response to standardized exercise training programs
    • Bouchard C, Sarzynski MA, Rice TK, et al. Genomic predictors of the maximal O uptake response to standardized exercise training programs. J Appl Physiol 2011; 110(5): 1160-1170.
    • (2011) J Appl Physiol , vol.110 , Issue.5 , pp. 1160-1170
    • Bouchard, C.1    Sarzynski, M.A.2    Rice, T.K.3
  • 103
    • 84859581041 scopus 로고    scopus 로고
    • Heritability of submaximal exercise heart rate response to exercise training is accounted for by nine SNPs
    • Rankinen T, Sung YJ, Sarzynski MA, Rice TK, Rao DC, Bouchard C. Heritability of submaximal exercise heart rate response to exercise training is accounted for by nine SNPs. J Appl Physiol 2012; 112(5): 892-897.
    • (2012) J Appl Physiol , vol.112 , Issue.5 , pp. 892-897
    • Rankinen, T.1    Sung, Y.J.2    Sarzynski, M.A.3    Rice, T.K.4    Rao, D.C.5    Bouchard, C.6
  • 104
    • 84881531434 scopus 로고    scopus 로고
    • A Prioritized Panel of Candidate Genes to be explored for Associations with the Blood Pressure Response to Exercise
    • In: Urbano KB, editor. NY: Nova
    • Ash GI, Augeri AL, Eicher JD, Bruneau Jr. ML, Pescatello LS. A Prioritized Panel of Candidate Genes to be explored for Associations with the Blood Pressure Response to Exercise. In: Urbano KB, editor. Advances in Genetics Research. Volume 9 Hauppage, NY: Nova; 2012.
    • (2012) Advances in Genetics Research. Hauppage , vol.9
    • Ash, G.I.1    Augeri, A.L.2    Eicher, J.D.3    Bruneau Jr., M.L.4    Pescatello, L.S.5
  • 105
    • 70349670733 scopus 로고    scopus 로고
    • Genome-Wide Association Study of Exercise Behavior in Dutch and American Adults
    • DE Moor MH, Liu YJ, Boomsma DI, et al. Genome-Wide Association Study of Exercise Behavior in Dutch and American Adults. Med Sci Sports Exerc 2009.
    • (2009) Med Sci Sports Exerc
    • Moor, M.H.1    Liu, Y.J.2    Boomsma, D.I.3
  • 106
    • 56349155783 scopus 로고    scopus 로고
    • Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies
    • Keating BJ, Tischfield S, Murray SS, et al. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. PLoS One 2008; 3(10): e3583.
    • (2008) PLoS One , vol.3 , Issue.10
    • Keating, B.J.1    Tischfield, S.2    Murray, S.S.3
  • 107
    • 80051499915 scopus 로고    scopus 로고
    • Rare-variant association testing for sequencing data with the sequence kernel association test
    • Wu MC, Lee S, Cai T, Li Y, Boehnke M, Lin X. Rare-variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet 2011; 89(1): 82-93.
    • (2011) Am J Hum Genet , vol.89 , Issue.1 , pp. 82-93
    • Wu, M.C.1    Lee, S.2    Cai, T.3    Li, Y.4    Boehnke, M.5    Lin, X.6
  • 108
    • 84877278573 scopus 로고    scopus 로고
    • Genome-wide Association Analysis for Multiple Continuous Secondary Phenotypes
    • Schifano ED, Li L, Christiani DC, Lin X. Genome-wide Association Analysis for Multiple Continuous Secondary Phenotypes. Am J Hum Genet 2013; 92(5): 744-759.
    • (2013) Am J Hum Genet , vol.92 , Issue.5 , pp. 744-759
    • Schifano, E.D.1    Li, L.2    Christiani, D.C.3    Lin, X.4
  • 109
    • 84876670093 scopus 로고    scopus 로고
    • Prospects for genetic risk prediction in hypertension
    • Padmanabhan S. Prospects for genetic risk prediction in hypertension. Hypertension 2013; 61(5): 961-963.
    • (2013) Hypertension , vol.61 , Issue.5 , pp. 961-963
    • Padmanabhan, S.1
  • 110
    • 84876690457 scopus 로고    scopus 로고
    • A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32,669 individuals
    • Havulinna AS, Kettunen J, Ukkola O, Osmond C, Eriksson JG, Kesaniemi YA, et al. A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32,669 individuals. Hypertension 2013; 61(5): 987-994.
    • (2013) Hypertension , vol.61 , Issue.5 , pp. 987-994
    • Havulinna, A.S.1    Kettunen, J.2    Ukkola, O.3    Osmond, C.4    Eriksson, J.G.5    Kesaniemi, Y.A.6
  • 111
    • 34250159524 scopus 로고    scopus 로고
    • Genome-wide mapping of in vivo protein-DNA interactions
    • Johnson DS, Mortazavi A, Myers RM, Wold B. Genome-wide mapping of in vivo protein-DNA interactions. Science 2007; 316(5830): 1497-1502.
    • (2007) Science , vol.316 , Issue.5830 , pp. 1497-1502
    • Johnson, D.S.1    Mortazavi, A.2    Myers, R.M.3    Wold, B.4
  • 112
    • 84866790609 scopus 로고    scopus 로고
    • Organization principles in genetic interaction networks
    • Jacobs C, Segre D. Organization principles in genetic interaction networks. Adv Exp Med Biol 2012; 751: 53-78.
    • (2012) Adv Exp Med Biol , vol.751 , pp. 53-78
    • Jacobs, C.1    Segre, D.2
  • 113
    • 67149090842 scopus 로고    scopus 로고
    • The human gene map for performance and health-related fitness phenotypes: The 2006-2007 update
    • Bray MS, Hagberg JM, Perusse L, et al. The human gene map for performance and health-related fitness phenotypes: the 2006-2007 update. Med Sci Sports Exerc 2009; 41(1): 35-73.
    • (2009) Med Sci Sports Exerc , vol.41 , Issue.1 , pp. 35-73
    • Bray, M.S.1    Hagberg, J.M.2    Perusse, L.3
  • 114
    • 15044361148 scopus 로고    scopus 로고
    • Blood pressure response to strength training may be influenced by angiotensinogen A-20C and angiotensin II type I receptor A1166C genotypes in older men and women
    • Delmonico MJ, Ferrell RE, Meerasahib A, et al. Blood pressure response to strength training may be influenced by angiotensinogen A-20C and angiotensin II type I receptor A1166C genotypes in older men and women. J Am Geriatr Soc 2005; 53(2): 204-210.
    • (2005) J Am Geriatr Soc , vol.53 , Issue.2 , pp. 204-210
    • Delmonico, M.J.1    Ferrell, R.E.2    Meerasahib, A.3
  • 115
    • 0032800446 scopus 로고    scopus 로고
    • Exercise training-induced blood pressure and plasma lipid improvements in hypertensives may be genotype dependent
    • Hagberg JM, Ferrell RE, Dengel DR, Wilund KR. Exercise training-induced blood pressure and plasma lipid improvements in hypertensives may be genotype dependent. Hypertension 1999; 34(1): 18-23.
    • (1999) Hypertension , vol.34 , Issue.1 , pp. 18-23
    • Hagberg, J.M.1    Ferrell, R.E.2    Dengel, D.R.3    Wilund, K.R.4
  • 116
    • 0348000623 scopus 로고    scopus 로고
    • Physical exercise and blood pressure with reference to the angiotensinogen M235T polymorphism
    • Rauramaa R, Kuhanen R, Lakka TA, et al. Physical exercise and blood pressure with reference to the angiotensinogen M235T polymorphism. Physiol Genomics 2002; 10(2):71-77.
    • (2002) Physiol Genomics , vol.10 , Issue.2 , pp. 71-77
    • Rauramaa, R.1    Kuhanen, R.2    Lakka, T.A.3
  • 117
    • 0036822068 scopus 로고    scopus 로고
    • Association of angiotensinconverting-enzyme gene polymorphism with the depressor response to mild exercise therapy in patients with mild to moderate essential hypertension
    • Zhang B, Sakai T, Miura S, et al. Association of angiotensinconverting-enzyme gene polymorphism with the depressor response to mild exercise therapy in patients with mild to moderate essential hypertension. Clin Genet 2002; 62(4): 328-333.
    • (2002) Clin Genet , vol.62 , Issue.4 , pp. 328-333
    • Zhang, B.1    Sakai, T.2    Miura, S.3
  • 118
    • 67650046463 scopus 로고    scopus 로고
    • Exercise training, NADPH oxidase p22phox gene polymorphisms, and hypertension
    • Feairheller DL, Brown MD, Park JY, et al. Exercise training, NADPH oxidase p22phox gene polymorphisms, and hypertension. Med Sci Sports Exerc 2009; 41(7): 1421-1428.
    • (2009) Med Sci Sports Exerc , vol.41 , Issue.7 , pp. 1421-1428
    • Feairheller, D.L.1    Brown, M.D.2    Park, J.Y.3
  • 119
    • 32044457362 scopus 로고    scopus 로고
    • Variation in the lipoprotein lipase gene influences exercise-induced left ventricular growth
    • Flavell DM, Wootton PT, Myerson SG, et al. Variation in the lipoprotein lipase gene influences exercise-induced left ventricular growth. J Mol Med 2006; 84(2): 126-131.
    • (2006) J Mol Med , vol.84 , Issue.2 , pp. 126-131
    • Flavell, D.M.1    Wootton, P.T.2    Myerson, S.G.3
  • 120
    • 33746852382 scopus 로고    scopus 로고
    • Influence of ALA54THR polymorphism of fatty acid binding protein 2 on lifestyle modification response in obese subjects
    • de Luis DA, Aller R, Izaola O, Sagrado MG, Conde R. Influence of ALA54THR polymorphism of fatty acid binding protein 2 on lifestyle modification response in obese subjects. Ann Nutr Metab 2006; 50(4): 354-360.
    • (2006) Ann Nutr Metab , vol.50 , Issue.4 , pp. 354-360
    • de Luis, D.A.1    Aller, R.2    Izaola, O.3    Sagrado, M.G.4    Conde, R.5
  • 121
    • 38749153653 scopus 로고    scopus 로고
    • Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study
    • Kilpelainen TO, Lakka TA, Laaksonen DE, et al. Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study. Metabolism 2008; 57(3): 428-436.
    • (2008) Metabolism , vol.57 , Issue.3 , pp. 428-436
    • Kilpelainen, T.O.1    Lakka, T.A.2    Laaksonen, D.E.3
  • 123
    • 84856078602 scopus 로고    scopus 로고
    • Exercise training prevents the microvascular rarefaction in hypertension balancing angiogenic and apoptotic factors: Role of microRNAs-16,-21, and-126
    • Fernandes T, Magalhaes FC, Roque FR, Phillips MI, Oliveira EM. Exercise training prevents the microvascular rarefaction in hypertension balancing angiogenic and apoptotic factors: role of microRNAs-16,-21, and-126. Hypertension 2012; 59(2): 513-520.
    • (2012) Hypertension , vol.59 , Issue.2 , pp. 513-520
    • Fernandes, T.1    Magalhaes, F.C.2    Roque, F.R.3    Phillips, M.I.4    Oliveira, E.M.5
  • 124
    • 84857636799 scopus 로고    scopus 로고
    • MicroRNAs in hypertension: Mechanisms and therapeutic targets
    • Batkai S, Thum T. MicroRNAs in hypertension: mechanisms and therapeutic targets. Curr Hypertens Rep 2012; 14(1): 79-87.
    • (2012) Curr Hypertens Rep , vol.14 , Issue.1 , pp. 79-87
    • Batkai, S.1    Thum, T.2
  • 125
    • 4644231710 scopus 로고    scopus 로고
    • DNA methylation is a nonredundant repressor of the Th2 effector program
    • Makar KW, Wilson CB. DNA methylation is a nonredundant repressor of the Th2 effector program. J Immunol 2004; 173(7): 4402-4406.
    • (2004) J Immunol , vol.173 , Issue.7 , pp. 4402-4406
    • Makar, K.W.1    Wilson, C.B.2
  • 126
    • 0035282903 scopus 로고    scopus 로고
    • Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition
    • Chen Z, Karaplis AC, Ackerman SL, et al. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Hum Mol Genet 2001; 10(5): 433-443.
    • (2001) Hum Mol Genet , vol.10 , Issue.5 , pp. 433-443
    • Chen, Z.1    Karaplis, A.C.2    Ackerman, S.L.3
  • 127
    • 3142672297 scopus 로고    scopus 로고
    • DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E
    • Lund G, Andersson L, Lauria M, et al. DNA methylation polymorphisms precede any histological sign of atherosclerosis in mice lacking apolipoprotein E. J Biol Chem 2004; 279(28): 29147-29154.
    • (2004) J Biol Chem , vol.279 , Issue.28 , pp. 29147-29154
    • Lund, G.1    Andersson, L.2    Lauria, M.3
  • 129
    • 77649260034 scopus 로고    scopus 로고
    • Global DNA methylation changes in blood of patients with essential hypertension
    • Smolarek I, Wyszko E, Barciszewska AM, et al. Global DNA methylation changes in blood of patients with essential hypertension. Med Sci Monit 2010; 16(3): CR149-155.
    • (2010) Med Sci Monit , vol.16 , Issue.3
    • Smolarek, I.1    Wyszko, E.2    Barciszewska, A.M.3
  • 130
    • 47649085663 scopus 로고    scopus 로고
    • Epigenetic control of 11 betahydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension
    • Friso S, Pizzolo F, Choi SW, et al. Epigenetic control of 11 betahydroxysteroid dehydrogenase 2 gene promoter is related to human hypertension. Atherosclerosis 2008; 199(2): 323-327.
    • (2008) Atherosclerosis , vol.199 , Issue.2 , pp. 323-327
    • Friso, S.1    Pizzolo, F.2    Choi, S.W.3
  • 131
    • 0037338365 scopus 로고    scopus 로고
    • Proteomic analysis of post-translational modifications
    • Mann M, Jensen ON. Proteomic analysis of post-translational modifications. Nat Biotechnol 2003; 21(3): 255-261.
    • (2003) Nat Biotechnol , vol.21 , Issue.3 , pp. 255-261
    • Mann, M.1    Jensen, O.N.2
  • 132
    • 79251488202 scopus 로고    scopus 로고
    • A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype
    • Keller P, Vollaard NB, Gustafsson T, et al. A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype. J Appl Physiol 2011; 110(1): 46-59.
    • (2011) J Appl Physiol , vol.110 , Issue.1 , pp. 46-59
    • Keller, P.1    Vollaard, N.B.2    Gustafsson, T.3
  • 133
    • 77953164300 scopus 로고    scopus 로고
    • Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans
    • Timmons JA, Knudsen S, Rankinen T, et al. Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol 2010; 108(6): 1487-1496.
    • (2010) J Appl Physiol , vol.108 , Issue.6 , pp. 1487-1496
    • Timmons, J.A.1    Knudsen, S.2    Rankinen, T.3
  • 134
    • 84876012664 scopus 로고    scopus 로고
    • Molecular networks of human muscle adaptation to exercise and age
    • Phillips BE, Williams JP, Gustafsson T, et al. Molecular networks of human muscle adaptation to exercise and age. PLoS Genet 2013; 9(3): e1003389.
    • (2013) PLoS Genet , vol.9 , Issue.3
    • Phillips, B.E.1    Williams, J.P.2    Gustafsson, T.3
  • 135
    • 79951970116 scopus 로고    scopus 로고
    • Current understanding of the genetic basis for physical activity
    • Lightfoot JT. Current understanding of the genetic basis for physical activity. J Nutr 2011; 141(3): 526-530.
    • (2011) J Nutr , vol.141 , Issue.3 , pp. 526-530
    • Lightfoot, J.T.1
  • 136
    • 77956887506 scopus 로고
    • A note on a general definition of the coefficient of determination
    • Nagelkerke NJD. A note on a general definition of the coefficient of determination. Biometrika 1991; 78(3): 691-692.
    • (1991) Biometrika , vol.78 , Issue.3 , pp. 691-692
    • Nagelkerke, N.J.D.1


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