Nitric oxide, cardiovascular disease and physical exercise;Óxido nítrico, doenças cardiovasculares e exercício físico

Arquivos Brasileiros de Cardiologia

Volumn 87, Issue 6, 2006, Pages

  Zago, Anderson Saranz ^a   Zanesco, Angelina ^a,b  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b NONE   (Brazil)

Author keywords

Cardiovascular disease; Nitric oxide; Physical exercise

Indexed keywords

NITRIC OXIDE;

ARTERIAL PRESSURE; ATHEROSCLEROSIS; BLOOD PRESSURE REGULATION; CARDIOVASCULAR DISEASE; DYSLIPIDEMIA; ENDOTHELIUM CELL; EXERCISE; HUMAN; HYPERTENSION; PHYSICAL ACTIVITY; REVIEW; VASCULAR ENDOTHELIUM;

EID: 33846636038     PISSN: 0066782X     EISSN: 16784170     Source Type: Journal    
DOI: 10.1590/S0066-782X2006001900029     Document Type: Review

References (76)

1. Dórea EL, Lotufo PA. Epidemiologia da hipertensão arterial sistêmica. Hipertensão. 2004; 7: 86-9.
2. MacKay J, Mensah GA (eds)〉 The atlas of heart disease and stroke. Geneva: WHO; 2004.
3. aed. Philadelphia: W.B. Saunders Company, 1996.
4. Milnor GL. Hypothalamic control of baroreceptor. Am J Physiol. 1970; 218: 124-31.
5. Krieger EM. Neurogenic hypertension in the rat. Circ Res. 1964; 15: 511-21.
6. Machado BH, Mauad H, Glass ML. Transient changes in blood pressure during spontaneous deep breaths in rats with sinoaortic deafferentation. J Appl Physiol. 1992; 72: 920-4.
7. Barros RC, Bonagamba LG, Okamoto-Canesin R, Oliveira M, Branco LG, Machado BH. Cardiovascular responses to chemoreflex activation with potassium cyanide or hypoxic hypoxia in awake rats. Auton Neurosci. 2002; 97: 110-5.
8. Fernandes LG, Antunes VR, Bonagamba LG, Machado BH. Pressor response to chemoreflex activation in awake rats: role of vasopressin and adrenal medulla. Physiol Behav. 2005; 84: 39-44.
9. Cogolludo A, Vizcaíno FP, Tamargo J. New insights in the pharmacological therapy of arterial hypertension. Curr Opin Nephrol Hypertens. 2005; 14: 423-7.
10. Zanesco A, Antunes E. Células endoteliais. In: Carvalho HF, Buzato CBC. Células: uma abordagem multidisciplinar, São Paulo: Manole, 2005.
11. Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature. 1980; 288: 373-6.
12. Ignarro LJ, Byrns R, Buga GM, Wood RS, Chaudhuri G. Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study the endothelium-dependent and nitric oxide elicited vascular smooth muscle relaxation. J Pharmacol Exp Ther. 1987; 244: 1-9.
13. Palmer RMJ, Ferridge AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 1987; 327: 524-6.
14. Vanhoutte PM. Endothelial control of vasomotor function - From health to coronary disease. Circ J. 2003; 67: 572-5.
15. Yanagisawa M, Kurihara H, Kimura S, Goto K, Masaki T. A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channels. J Hypertens. 1989; 6 (4 Suppl.): S188-91.
16. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology pathophysiology and pharmacology. Pharmacol Rev. 1991; 43: 109-42.
17. Cohen RA, Vanhoutte PM. Endothelium-Dependent Hyperpolarization - Beyond Nitric Oxide and Cyclic GMP. Circulation. 1995; 92: 3337-49.
18. a ed. São Paulo: Sarvier; 2002.
19. Palmer RMJ, Ashton DS, Moncada S. Vascular endotelial cells synthesize nitric oxide from L-arginine. Nature. 1988; 333: 664-6.
20. Bredt DS, Hwang PM, Glatt CE, Lowenstein C, Reed RR, Snyder SH. Cloned and expression nitric oxide synthase structurally resembles cytocrome P-450 reductase. Nature. 1991; 351: 714-8.
21. Mombouli JV, Vanhoutte PM. Endothelial dysfunction: from physiology to therapy. J Mol Cell Cardiol. 1999; 31: 61-74.
22. Moncada S. Nitric Oxide in the vasculature: physiology and pathophysiology. An New York Acad Sci. 1997; 811: 60-7.
23. Schulz R, Triggle CR. Role of NO in vascular smooth muscle and cardiac muscle function. Trends Pharmacol Sci. 1994; 15: 255-9.
24. Dominiczack AF, Bohr DF. Nitric oxide and its putative role in hypertension. Hypertension. 1995; 25: 1202-11.
25. Tibiriça E. Fisiopatologia em medicina cardiovascular. Rio de Janeiro: Revinter; 2001.
26. Moncada S. Physiological effects of nitric oxide. J Hypertens. 1994; 12: 35-9.
27. Sessa WC, Pritchard K, Seyedi N, Wang J, Hintze TH. Chronic exercise in dog increase coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression. Circ Res. 1994; 74: 349-53.
28. Higashi Y, Sasaki S, Sasaki N, Nakagawa K, Ueda T, Yoshimizu A, et al. Daily aerobic exercise improves reactive hyperemia in patients with essential hypertension. Hypertension. 1999; 33:591-7.
29. Fisher AB, Chien S, Barakat AI, Nerem RN. Endothelial cellular response to altered shear stress. Am J Physiol. 2001; 281: L529-L533.
30. Boo YC, Jo H. Flow-dependent regulation of endothelial nitric oxide synthase: role of protein kinases. Am J Physiol. 2005; 285: C499-C508.
31. Murad F, Forstermann U, Nakane M, Schimidt H, Pollock J, Sheng H, et al. The nitric oxide-cyclic GMP signal transduction pathway in vascular smooth muscle preparations and other tissues. Jpn J Pharmacol. 1992; 58: 150-7.
32. a ed. Rio de Janeiro: Guanabara Koogan; 2003.
33. Murad F, Forstermann U, Nakane M, Pollock J, Tracey R, Matsumoto T, et al. The nitric oxide-cyclic GMP signal transduction system for intracellular and intercellular communication. Adv Second Messenger Phosphoprotein Res. 1993; 28: 101-9.
34. Scott-Burden T, Vanhoutte PM. The endothelium as a regulator of vascular smooth muscle proliferation. Circulation. 1993; 87 (Suppl. 5): 51-5.
35. Webb RC. Smooth muscle contraction and relaxation. Adv Physiol Educ. 2003; 27: 201-6.
36. Rosselli M, Imthurn B, Keller PJ, Jackson EK, Dubey RK. Circulating Nitric Oxide (nitrite/nitrate) levels in postmenopausal women substituted with 17β-estradiol and norethisterone acetate - A two-year follow-up study. Hypertension. 1995; 25: 848-53.
37. Best PJM, Berger PB, Miller VM, Lerman A. The effect of estrogen replacement therapy on plasma nitric oxide and endothelin-1 levels in postmenopausal women. Ann Int Med. 1998; 128: 285-8.
38. Drexler H, Hornig B. Endothelial dysfunction in human disease. J Mol Cell Cardiol. 1999; 31: 51-60.
39. Viaro F, Nobre F, Evora RB. Expressão das óxido nítrico sintase na fisiopatologia das doenças cardiovasculares. Arq Bras Cardiol. 2000; 74: 365-79.
40. Kingwell BA. Nitric oxide-mediated metabolic regulation during exercise: effects of training in health and cardiovascular disease. FASEB J. 2000; 14: 1685-96.
41. Parthasarathy S, Steinberg D, Witztum JL. The role of oxidized low-density lipoproteins in the patogénesis of atherosclerosis. Ann Rev Med. 1992; 43: 219-25.
42. Curi R, Pompéia C, Miyasaka CK, Procopio J. Entendendo a gordura - os ácidos graxos. São Paulo: Manole; 2002.
43. Moro MA, Russel RJ, Cellek S, Lizasoain I, Su Y, Darley-Usmar VM, et al. cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase. Proc Natl Acad Sci. 1996; 93: 1480-5.
44. Hobbs AJ, Moncada S. Antiplatelet properties of a novel, non-NO-based soluble guanylate cyclase activator. Vasc Pharmacol. 2003; 40: 149-54.
45. Hettzer T, Ylä-Herttuala S, Luoma L, Kurz S, Münzel T, Just J, et al. Cigarette smoking potentials endothelial dysfunction of forearm resistance vessel in patients with hypercholesterolemia. Circulation. 1996; 93: 1346-53.
46. Rosenson RS. Statin in atherosclerosis: lipid-lowering agents with antioxidant capabilities. Atherosclerosis. 2004; 173: 1-12.
47. Bolad I, Delafontaine P. Endothelial dysfunction: its role in hypertension coronary disease. Curr Opin Cardiol. 2005; 20: 270-4.
48. Levine B, Kalman J, Mayer L, Fillit HM, Packer M. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Engl J Med. 1990; 323: 236-41.
49. Nunes APOB, Rios ACS, Cunha GA, Barretto ACP, Negrão CE. Efeitos de um programa de exercício físico não supervisionado e acompanhado a distância, via Internet, sobre a pressão arterial e composição corporal em indivíduos normotensos e pré-hipertensos. Arq Bras Cardiol. 2006; 86: 289-96.
50. Kenney MJ, Seals DR. Postexercise hypotension. Hypertension. 1993; 22: 653-64.
51. Tipton CM, Mathees RD, Bedford TG. Influence of training on the blood pressure changes during lower body negative pressure in rats. Med Sci Sports Exerc. 1982; 14: 81-90.
52. Grassi G, Seravalle G, Calboun DA, Mancia G. Physical training and baroreceptor control of sympathetic nerve activity in human. Hypertension. 1994; 23: 294-301.
53. Franklin BA, Seymour G, Timmis GC. Exercise prescription for hypertensive patients. Ann Med. 1991; 23: 279-87.
54. Negrão CE, Irigoyen MC, Moreira ED, Brum PC, Freire PM, Krieger EM. Effect of exercise training on RSNA, baroreflex control, and blood pressure responsiveness. Am J Physiol. 1993; 265: 365-70.
55. Gava NS, Veras-Silva AS, Negrão CE, Krieger EM. Low-intensity exercise training attenuates cardiac beta-adrenergic tone during exercise in spontaneously hypertensive rats. Hypertension. 1995; 26: 1129-33.
56. Pescatello LS, Franklin BA, Fagard R, Farguhar WB, Kelley GA, Ray CA, et al. American College of Sports Medicine position stand Exercise and Hypertension. Med Sci Sports Exerc. 2004; 36: 533-53.
57. Monteiro MF, Sobral Fo DC. Exercício físico e o controle da pressão arterial. Rev Bras Med Esporte. 2004; 10: 513-6.
58. Gardiner SM, Compton AM, Kemp PA, Bennett T. Regional and haemodynamic effects of NG-nitro-L-arginine methyl ester in conscious long evans rats. Br J Pharmacol. 1990; 101: 625-31.
59. Klabunde RE, Ritger RC, Helgren MC. Cardiovascular actions of inhibitors of endothelium-derived relaxing factors (nitric oxide) formation release in anesthetized dogs. Eur J Pharmacol. 1991; 199: 51-9.
60. Richard V, Berdeaux A, La Rochelle CD, Giudicelli JF. Regional coronary hemodynamic effects of two inhibitor of nitric oxide synthase in anesthetized, open-chest dogs. Br J Pharmacol. 1991; 104: 59-64.
61. Ribeiro MO, Antunes E, De Nucci G, Lovisolo SM, Zatz R. Chronic inhibition of nitric oxide synthase - A new model of arterial hypertension. Hypertension. 1992; 20: 298-303.
62. Zatz R, Bayliss C. Chronic nitric oxide inhibition model six years on. Hypertension. 1998; 32: 958-64.
63. Riado SR, Zanesco A, Barker LA, De Lucca IMS, Antunes E, De Nucci G. Long-term nitric oxide inhibition and chronotrotic response in rat isolated right atria. Hypertension. 1999; 34: 802-7.
64. Baylis C, Mitruka B, Deng A. Chronic blockade of nitric oxide synthesis in the rat produces systemic hypertension and glomerular damage. J Clin Invest. 1992; 90: 278-81.
65. Moreno Jr H, Metze K, Bento AC, Antunes E, Zatz R, De Nucci G. Chronic nitric oxide inhibition as a model of hypertensive heart muscle disease. Basic Res Cardiovasc. 1996; 91: 248-55.
66. Batal P, Pechanova O, Bernatova I, Stvrtina S. Chronic inhibition of NO synthesis produces myocardial fibrosis and arterial media hyperplasia. Histol Histopathol. 1997; 12: 623-9.
67. Devli AM, Brosnan MJ, Graham D, Morton JJ, Mcphaden AR, Mcintyre M, et al. Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo. Am J Physiol. 1998; 274: H52-H59.
68. Luvara G, Pueyo ME, Phillippe M, Mandet C, Savoie F, Henrion D, et al. Chronic blockade of NO synthase activity induces a proinflammatory phenotype in the arterial wall: prevention by angiotension II antagonism. Arterioscler Thromb Vasc Biol. 1998; 18: 1408-16.
69. Delp MD, Mcallister RM, Laughlin MH. Exercise training alters endothelium-dependent vasoreactivity of rat abdominal aorta. J Appl Physiol. 1993; 75: 1354-63.
70. Roberts K, Barnard RJ, Jasman A, Balon TW. Acute exercise increase nitric oxide synthase activity in skeletal muscle. Am J Physiol. 1999; 277: E390-E394.
71. Kuru O, Sentürk UK, Demir N, Yesilkaya A, Ergüler G, Erkiliç M. Effect of exercise on blood pressure in rats with chronic NOS inhibition. Eur J Appl Physiol. 2002; 87: 134-40.
72. Griffin KL, Laughlin MH, Parker JL. Exercise training improves endothelium-mediated vasorelaxarion after chronic coronary occlusion. J Appl Physiol. 1999; 87: 1948-56.
73. Clarkson P, Montgomery H, Mullen M, Donald A, Powe A, Bull T, et al. Exercise training enhances endothelial function in young men. J Am Coll Cardiol. 1999; 33: 1379-85.
74. Claudino MA, Priviero FBM, Teixeira C, De Nucci G, Antunes G, Zanesco A. Improvement in relaxation response in corpus cavernosun from trained rats. Urology. 2004; 63: 1004-8.
75. Shen W, Rundborg M, Wang J, Stewart JM, Xu X, Ochoa M, et al. Role of EDRF in the regulation of regional blood flow and vascular resistance at rest and during exercise in conscious dog. J Appl Physiol. 1994; 77: 165-72.
76. Kingwell B, Sherrard B, Jennings G, Dart A. Four weeks of cycle training increases basal production of nitric oxide from the forearm. Am J Physiol. 1997; 272: H1070-H1077.