-
1
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
T.A. Manolio, F.S. Collins, N.J. Cox, D.B. Goldstein, L.A. Hindorff, D.J. Hunter, M.I. McCarthy, E.M. Ramos, L.R. Cardon, and A. Chakravarti Finding the missing heritability of complex diseases Nature 461 2009 747 753
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
McCarthy, M.I.7
Ramos, E.M.8
Cardon, L.R.9
Chakravarti, A.10
-
2
-
-
34250001297
-
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
-
D.J. Hunter, P. Kraft, K.B. Jacobs, D.G. Cox, M. Yeager, S.E. Hankinson, S. Wacholder, Z. Wang, R. Welch, and A. Hutchinson A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer Nat. Genet. 39 2007 870 874
-
(2007)
Nat. Genet.
, vol.39
, pp. 870-874
-
-
Hunter, D.J.1
Kraft, P.2
Jacobs, K.B.3
Cox, D.G.4
Yeager, M.5
Hankinson, S.E.6
Wacholder, S.7
Wang, Z.8
Welch, R.9
Hutchinson, A.10
-
3
-
-
39749118602
-
Multiple loci identified in a genome-wide association study of prostate cancer
-
G. Thomas, K.B. Jacobs, M. Yeager, P. Kraft, S. Wacholder, N. Orr, K. Yu, N. Chatterjee, R. Welch, and A. Hutchinson Multiple loci identified in a genome-wide association study of prostate cancer Nat. Genet. 40 2008 310 315
-
(2008)
Nat. Genet.
, vol.40
, pp. 310-315
-
-
Thomas, G.1
Jacobs, K.B.2
Yeager, M.3
Kraft, P.4
Wacholder, S.5
Orr, N.6
Yu, K.7
Chatterjee, N.8
Welch, R.9
Hutchinson, A.10
-
4
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
L.J. Scott, K.L. Mohlke, L.L. Bonnycastle, C.J. Willer, Y. Li, W.L. Duren, M.R. Erdos, H.M. Stringham, P.S. Chines, and A.U. Jackson A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants Science 316 2007 1341 1345
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
Erdos, M.R.7
Stringham, H.M.8
Chines, P.S.9
Jackson, A.U.10
-
5
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Wellcome Trust Case Control Consortium Genetic Investigation of ANthropometric Traits Consortium
-
C.J. Willer, E.K. Speliotes, R.J. Loos, S. Li, C.M. Lindgren, I.M. Heid, S.I. Berndt, A.L. Elliott, A.U. Jackson, C. Lamina Wellcome Trust Case Control Consortium Genetic Investigation of ANthropometric Traits Consortium Six new loci associated with body mass index highlight a neuronal influence on body weight regulation Nat. Genet. 41 2009 25 34
-
(2009)
Nat. Genet.
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
Li, S.4
Lindgren, C.M.5
Heid, I.M.6
Berndt, S.I.7
Elliott, A.L.8
Jackson, A.U.9
Lamina, C.10
-
6
-
-
66649090056
-
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
-
C. He, P. Kraft, C. Chen, J.E. Buring, G. Paré, S.E. Hankinson, S.J. Chanock, P.M. Ridker, D.J. Hunter, and D.I. Chasman Genome-wide association studies identify loci associated with age at menarche and age at natural menopause Nat. Genet. 41 2009 724 728
-
(2009)
Nat. Genet.
, vol.41
, pp. 724-728
-
-
He, C.1
Kraft, P.2
Chen, C.3
Buring, J.E.4
Paré, G.5
Hankinson, S.E.6
Chanock, S.J.7
Ridker, P.M.8
Hunter, D.J.9
Chasman, D.I.10
-
7
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
H. Lango Allen, K. Estrada, G. Lettre, S.I. Berndt, M.N. Weedon, F. Rivadeneira, C.J. Willer, A.U. Jackson, S. Vedantam, and S. Raychaudhuri Hundreds of variants clustered in genomic loci and biological pathways affect human height Nature 467 2010 832 838
-
(2010)
Nature
, vol.467
, pp. 832-838
-
-
Lango Allen, H.1
Estrada, K.2
Lettre, G.3
Berndt, S.I.4
Weedon, M.N.5
Rivadeneira, F.6
Willer, C.J.7
Jackson, A.U.8
Vedantam, S.9
Raychaudhuri, S.10
-
9
-
-
70449575858
-
Genome-wide association scans for secondary traits using case-control samples
-
G.M. Monsees, R.M. Tamimi, and P. Kraft Genome-wide association scans for secondary traits using case-control samples Genet. Epidemiol. 33 2009 717 728
-
(2009)
Genet. Epidemiol.
, vol.33
, pp. 717-728
-
-
Monsees, G.M.1
Tamimi, R.M.2
Kraft, P.3
-
10
-
-
42649091460
-
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1
-
C.I. Amos, X. Wu, P. Broderick, I.P. Gorlov, J. Gu, T. Eisen, Q. Dong, Q. Zhang, X. Gu, and J. Vijayakrishnan Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1 Nat. Genet. 40 2008 616 622
-
(2008)
Nat. Genet.
, vol.40
, pp. 616-622
-
-
Amos, C.I.1
Wu, X.2
Broderick, P.3
Gorlov, I.P.4
Gu, J.5
Eisen, T.6
Dong, Q.7
Zhang, Q.8
Gu, X.9
Vijayakrishnan, J.10
-
11
-
-
41649103682
-
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
-
R.J. Hung, J.D. McKay, V. Gaborieau, P. Boffetta, M. Hashibe, D. Zaridze, A. Mukeria, N. Szeszenia-Dabrowska, J. Lissowska, and P. Rudnai A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25 Nature 452 2008 633 637
-
(2008)
Nature
, vol.452
, pp. 633-637
-
-
Hung, R.J.1
McKay, J.D.2
Gaborieau, V.3
Boffetta, P.4
Hashibe, M.5
Zaridze, D.6
Mukeria, A.7
Szeszenia-Dabrowska, N.8
Lissowska, J.9
Rudnai, P.10
-
12
-
-
66249126496
-
Proper analysis of secondary phenotype data in case-control association studies
-
D.Y. Lin, and D. Zeng Proper analysis of secondary phenotype data in case-control association studies Genet. Epidemiol. 33 2009 256 265
-
(2009)
Genet. Epidemiol.
, vol.33
, pp. 256-265
-
-
Lin, D.Y.1
Zeng, D.2
-
14
-
-
0141905064
-
Scaled marginal models for multiple continuous outcomes
-
J. Roy, X. Lin, and L.M. Ryan Scaled marginal models for multiple continuous outcomes Biostatistics 4 2003 371 383
-
(2003)
Biostatistics
, vol.4
, pp. 371-383
-
-
Roy, J.1
Lin, X.2
Ryan, L.M.3
-
15
-
-
77649173768
-
Longitudinal data analysis using generalized linear models
-
K.Y. Liang, and S. Zeger Longitudinal data analysis using generalized linear models Biometrika 73 1986 13 22
-
(1986)
Biometrika
, vol.73
, pp. 13-22
-
-
Liang, K.Y.1
Zeger, S.2
-
16
-
-
29844444766
-
The R Package geepack for Generalized Estimating Equations
-
S. Hjsgaard, U. Halekoh, and J. Yan The R Package geepack for Generalized Estimating Equations J. Stat. Softw. 15 2005 1 11
-
(2005)
J. Stat. Softw.
, vol.15
, pp. 1-11
-
-
Hjsgaard, S.1
Halekoh, U.2
Yan, J.3
-
17
-
-
79952117042
-
Odds ratios for mediation analysis for a dichotomous outcome
-
T.J. Vanderweele, and S. Vansteelandt Odds ratios for mediation analysis for a dichotomous outcome Am. J. Epidemiol. 172 2010 1339 1348
-
(2010)
Am. J. Epidemiol.
, vol.172
, pp. 1339-1348
-
-
Vanderweele, T.J.1
Vansteelandt, S.2
-
18
-
-
36749079336
-
So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests
-
K.N. Conneely, and M. Boehnke So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests Am. J. Hum. Genet. 81 2007 1158 1168
-
(2007)
Am. J. Hum. Genet.
, vol.81
, pp. 1158-1168
-
-
Conneely, K.N.1
Boehnke, M.2
-
19
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
A.L. Price, N.J. Patterson, R.M. Plenge, M.E. Weinblatt, N.A. Shadick, and D. Reich Principal components analysis corrects for stratification in genome-wide association studies Nat. Genet. 38 2006 904 909
-
(2006)
Nat. Genet.
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
20
-
-
77954267769
-
Personalized smoking cessation: Interactions between nicotine dose, dependence and quit-success genotype score
-
J.E. Rose, F.M. Behm, T. Drgon, C. Johnson, and G.R. Uhl Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score Mol. Med. 16 2010 247 253
-
(2010)
Mol. Med.
, vol.16
, pp. 247-253
-
-
Rose, J.E.1
Behm, F.M.2
Drgon, T.3
Johnson, C.4
Uhl, G.R.5
-
21
-
-
33846510020
-
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs
-
S.F. Saccone, A.L. Hinrichs, N.L. Saccone, G.A. Chase, K. Konvicka, P.A. Madden, N. Breslau, E.O. Johnson, D. Hatsukami, and O. Pomerleau Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs Hum. Mol. Genet. 16 2007 36 49
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 36-49
-
-
Saccone, S.F.1
Hinrichs, A.L.2
Saccone, N.L.3
Chase, G.A.4
Konvicka, K.5
Madden, P.A.6
Breslau, N.7
Johnson, E.O.8
Hatsukami, D.9
Pomerleau, O.10
-
22
-
-
55749093830
-
The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer
-
M.R. Spitz, C.I. Amos, Q. Dong, J. Lin, and X. Wu The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer J. Natl. Cancer Inst. 100 2008 1552 1556
-
(2008)
J. Natl. Cancer Inst.
, vol.100
, pp. 1552-1556
-
-
Spitz, M.R.1
Amos, C.I.2
Dong, Q.3
Lin, J.4
Wu, X.5
-
23
-
-
48249105897
-
A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction
-
R.B. Weiss, T.B. Baker, D.S. Cannon, A. von Niederhausern, D.M. Dunn, N. Matsunami, N.A. Singh, L. Baird, H. Coon, and W.M. McMahon A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction PLoS Genet. 4 2008 e1000125
-
(2008)
PLoS Genet.
, vol.4
, pp. 1000125
-
-
Weiss, R.B.1
Baker, T.B.2
Cannon, D.S.3
Von Niederhausern, A.4
Dunn, D.M.5
Matsunami, N.6
Singh, N.A.7
Baird, L.8
Coon, H.9
McMahon, W.M.10
-
24
-
-
57449114734
-
Nicotinic receptor gene variants influence susceptibility to heavy smoking
-
V.L. Stevens, L.J. Bierut, J.T. Talbot, J.C. Wang, J. Sun, A.L. Hinrichs, M.J. Thun, A. Goate, and E.E. Calle Nicotinic receptor gene variants influence susceptibility to heavy smoking Cancer Epidemiol. Biomarkers Prev. 17 2008 3517 3525
-
(2008)
Cancer Epidemiol. Biomarkers Prev.
, vol.17
, pp. 3517-3525
-
-
Stevens, V.L.1
Bierut, L.J.2
Talbot, J.T.3
Wang, J.C.4
Sun, J.5
Hinrichs, A.L.6
Thun, M.J.7
Goate, A.8
Calle, E.E.9
-
25
-
-
77951711343
-
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
-
Tobacco and Genetics Consortium
-
H. Furberg, Y. Kim, J. Dackor, E. Boerwinkle, N. Franceschini, D. Ardissino, L. Bernardinelli, P.L. Mannucci, F. Mauri, P.A. Merlini Tobacco and Genetics Consortium Genome-wide meta-analyses identify multiple loci associated with smoking behavior Nat. Genet. 42 2010 441 447
-
(2010)
Nat. Genet.
, vol.42
, pp. 441-447
-
-
Furberg, H.1
Kim, Y.2
Dackor, J.3
Boerwinkle, E.4
Franceschini, N.5
Ardissino, D.6
Bernardinelli, L.7
Mannucci, P.L.8
Mauri, F.9
Merlini, P.A.10
-
26
-
-
77951751034
-
Meta-analysis and imputation refines the association of 15q25 with smoking quantity
-
Wellcome Trust Case Control Consortium
-
J.Z. Liu, F. Tozzi, D.M. Waterworth, S.G. Pillai, P. Muglia, L. Middleton, W. Berrettini, C.W. Knouff, X. Yuan, G. Waeber Wellcome Trust Case Control Consortium Meta-analysis and imputation refines the association of 15q25 with smoking quantity Nat. Genet. 42 2010 436 440
-
(2010)
Nat. Genet.
, vol.42
, pp. 436-440
-
-
Liu, J.Z.1
Tozzi, F.2
Waterworth, D.M.3
Pillai, S.G.4
Muglia, P.5
Middleton, L.6
Berrettini, W.7
Knouff, C.W.8
Yuan, X.9
Waeber, G.10
-
27
-
-
77951748276
-
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior
-
ENGAGE Consortium
-
T.E. Thorgeirsson, D.F. Gudbjartsson, I. Surakka, J.M. Vink, N. Amin, F. Geller, P. Sulem, T. Rafnar, T. Esko, S. Walter ENGAGE Consortium Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior Nat. Genet. 42 2010 448 453
-
(2010)
Nat. Genet.
, vol.42
, pp. 448-453
-
-
Thorgeirsson, T.E.1
Gudbjartsson, D.F.2
Surakka, I.3
Vink, J.M.4
Amin, N.5
Geller, F.6
Sulem, P.7
Rafnar, T.8
Esko, T.9
Walter, S.10
-
28
-
-
77957366301
-
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: A meta-analysis and comparison with lung cancer and COPD
-
N.L. Saccone, R.C. Culverhouse, T.-H. Schwantes-An, D.S. Cannon, X. Chen, S. Cichon, I. Giegling, S. Han, Y. Han, and K. Keskitalo-Vuokko Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD PLoS Genet. 6 2010 e1001053
-
(2010)
PLoS Genet.
, vol.6
, pp. 1001053
-
-
Saccone, N.L.1
Culverhouse, R.C.2
Schwantes-An, T.-H.3
Cannon, D.S.4
Chen, X.5
Cichon, S.6
Giegling, I.7
Han, S.8
Han, Y.9
Keskitalo-Vuokko, K.10
-
29
-
-
84861413864
-
Genetic variants on 15q25.1, smoking, and lung cancer: An assessment of mediation and interaction
-
T.J. VanderWeele, K. Asomaning, E.J. Tchetgen Tchetgen, Y. Han, M.R. Spitz, S. Shete, X. Wu, V. Gaborieau, Y. Wang, and J. McLaughlin Genetic variants on 15q25.1, smoking, and lung cancer: an assessment of mediation and interaction Am. J. Epidemiol. 175 2012 1013 1020
-
(2012)
Am. J. Epidemiol.
, vol.175
, pp. 1013-1020
-
-
Vanderweele, T.J.1
Asomaning, K.2
Tchetgen Tchetgen, E.J.3
Han, Y.4
Spitz, M.R.5
Shete, S.6
Wu, X.7
Gaborieau, V.8
Wang, Y.9
McLaughlin, J.10
-
30
-
-
84950455841
-
Tests of Hypotheses in Overdispersed Poisson Regression and Other Quasi-Likelihood Models
-
N. Breslow Tests of Hypotheses in Overdispersed Poisson Regression and Other Quasi-Likelihood Models JASA 85 1990 565 571
-
(1990)
JASA
, vol.85
, pp. 565-571
-
-
Breslow, N.1
|