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Volumn 3, Issue 22, 2013, Pages 8388-8397

One-pot synthesis of substituted indoles via titanium(iv) alkoxide mediated imine formation-copper-catalyzed N-arylation

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CATALYSIS; COPPER; CYCLIZATION; KETONES;

EID: 84881446712     PISSN: None     EISSN: 20462069     Source Type: Journal    
DOI: 10.1039/c3ra40389k     Document Type: Article
Times cited : (24)

References (93)
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  • 53
    • 77957549886 scopus 로고    scopus 로고
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    • J. Barluenga A. Jimenez-Aquino F. Aznar C. Valdes Chem.-Eur. J. 2010 16 11707
    • (2010) Chem.-Eur. J. , vol.16 , pp. 11707
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  • 70
    • 84866041300 scopus 로고    scopus 로고
    • For selected reports on the synthesis of indoles via Cu-catalyzed C-N-bond formation reactions, see
    • T. Liu H. Fu Synthesis 2012 2805
    • (2012) Synthesis , pp. 2805
    • Liu, T.1    Fu, H.2
  • 83
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    • Chen and Dormer (ref. 9a) attempted to obtain 1-benzyl-2-methylindole starting from (o-bromophenyl)acetone and benzylamine. The indole was expected to be achieved by a Cu-catalyzed intermolecular amination followed by an intramolecular ring closure. However, this sequence did not give the expected indole and the applied conditions afforded 2-methylbenzofuran exclusively
    • Z.-J. Wang J.-G. Yang F. Yang W. Bao Org. Lett. 2010 13 3034
    • (2010) Org. Lett. , vol.13 , pp. 3034
    • Wang, Z.-J.1    Yang, J.-G.2    Yang, F.3    Bao, W.4
  • 86
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    • For other examples of MPV reduction with titanium(iv) isopropoxide, see
    • S. Bhattacharyya J. Org. Chem. 1995 60 4928
    • (1995) J. Org. Chem. , vol.60 , pp. 4928
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  • 87
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    • For the synthesis of 2,3-dihydrobenzofurans via related Cu-catalyzed etherification, see
    • R. Mahrwald Org. Lett. 2000 2 4011
    • (2000) Org. Lett. , vol.2 , pp. 4011
    • Mahrwald, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.