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Volumn 341, Issue 6152, 2013, Pages

Dynamically reshaping signaling networks to program cell fate via genetic controllers

Author keywords

[No Author keywords available]

Indexed keywords

PHEROMONE; FUS1 PROTEIN, S CEREVISIAE; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SYNTHETIC DNA;

EID: 84881408628     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1235005     Document Type: Article
Times cited : (59)

References (52)
  • 1
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • pmid: 7601337
    • R. Seger, E. G. Krebs, The MAPK signaling cascade. FASEB J. 9, 726-735 (1995). pmid: 7601337
    • (1995) FASEB J. , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 2
    • 0036729484 scopus 로고    scopus 로고
    • Seven-transmembrane receptors
    • doi: 10.1038/nrm908; pmid: 12209124
    • K. L. Pierce, R. T. Premont, R. J. Lefkowitz, Seven-transmembrane receptors. Nat. Rev. Mol. Cell Biol. 3, 639-650 (2002). doi: 10.1038/nrm908; pmid: 12209124
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 639-650
    • Pierce, K.L.1    Premont, R.T.2    Lefkowitz, R.J.3
  • 3
    • 2342444610 scopus 로고    scopus 로고
    • Essential roles of Her2/erbB2 in cardiac development and function
    • doi: 10.1210/rp.59.1.1; pmid: 14749494
    • A. Negro, B. K. Brar, K. F. Lee, Essential roles of Her2/erbB2 in cardiac development and function. Recent Prog. Horm. Res. 59, 1-12 (2004). doi: 10.1210/rp.59.1.1; pmid: 14749494
    • (2004) Recent Prog. Horm. Res. , vol.59 , pp. 1-12
    • Negro, A.1    Brar, B.K.2    Lee, K.F.3
  • 4
    • 77952679687 scopus 로고    scopus 로고
    • Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems
    • doi: 10.1073/pnas.1001721107; pmid: 20421500
    • Y. Y. Chen, M. C. Jensen, C. D. Smolke, Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems. Proc. Natl. Acad. Sci. U.S.A. 107, 8531-8536 (2010). doi: 10.1073/pnas.1001721107; pmid: 20421500
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 8531-8536
    • Chen, Y.Y.1    Jensen, M.C.2    Smolke, C.D.3
  • 5
    • 78649429678 scopus 로고    scopus 로고
    • Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins
    • doi: 10.1126/science.1192128; pmid: 21109673
    • S. J. Culler, K. G. Hoff, C. D. Smolke, Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins. Science 330, 1251-1255 (2010). doi: 10.1126/science.1192128; pmid: 21109673
    • (2010) Science , vol.330 , pp. 1251-1255
    • Culler, S.J.1    Hoff, K.G.2    Smolke, C.D.3
  • 6
    • 29144482539 scopus 로고    scopus 로고
    • Environmentally controlled invasion of cancer cells by engineered bacteria
    • doi: 10.1016/j.jmb.2005.10.076; pmid: 16330045
    • J. C. Anderson, E. J. Clarke, A. P. Arkin, C. A. Voigt, Environmentally controlled invasion of cancer cells by engineered bacteria. J. Mol. Biol. 355, 619-627 (2006). doi: 10.1016/j.jmb.2005.10.076; pmid: 16330045
    • (2006) J. Mol. Biol. , vol.355 , pp. 619-627
    • Anderson, J.C.1    Clarke, E.J.2    Arkin, A.P.3    Voigt, C.A.4
  • 7
    • 77950676224 scopus 로고    scopus 로고
    • Self-sufficient control of urate homeostasis in mice by a synthetic circuit
    • doi: 10.1038/nbt.1617; pmid: 20351688
    • C. Kemmer et al., Self-sufficient control of urate homeostasis in mice by a synthetic circuit. Nat. Biotechnol. 28, 355-360 (2010). doi: 10.1038/nbt.1617; pmid: 20351688
    • (2010) Nat. Biotechnol. , vol.28 , pp. 355-360
    • Kemmer, C.1
  • 8
    • 34547521789 scopus 로고    scopus 로고
    • Synthetic ecosystems based on airborne inter- and intrakingdom communication
    • doi: 10.1073/pnas.0701382104; pmid: 17551014
    • W. Weber, M. Daoud-El Baba, M. Fussenegger, Synthetic ecosystems based on airborne inter- and intrakingdom communication. Proc. Natl. Acad. Sci. U.S.A. 104, 10435-10440 (2007). doi: 10.1073/pnas.0701382104; pmid: 17551014
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 10435-10440
    • Weber, W.1    Daoud-El Baba, M.2    Fussenegger, M.3
  • 9
    • 79959514813 scopus 로고    scopus 로고
    • A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice
    • doi: 10.1126/science.1203535; pmid: 21700876
    • H. Ye, M. Daoud-El Baba, R. W. Peng, M. Fussenegger, A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice. Science 332, 1565-1568 (2011). doi: 10.1126/science.1203535; pmid: 21700876
    • (2011) Science , vol.332 , pp. 1565-1568
    • Ye, H.1    Daoud-El Baba, M.2    Peng, R.W.3    Fussenegger, M.4
  • 10
    • 80052456127 scopus 로고    scopus 로고
    • Multi-input RNAi-based logic circuit for identification of specific cancer cells
    • doi: 10.1126/science.1205527; pmid: 21885784
    • Z. Xie, L. Wroblewska, L. Prochazka, R. Weiss, Y. Benenson, Multi-input RNAi-based logic circuit for identification of specific cancer cells. Science 333, 1307-1311 (2011). doi: 10.1126/science.1205527; pmid: 21885784
    • (2011) Science , vol.333 , pp. 1307-1311
    • Xie, Z.1    Wroblewska, L.2    Prochazka, L.3    Weiss, R.4    Benenson, Y.5
  • 11
    • 77957679279 scopus 로고    scopus 로고
    • Tracking, tuning, and terminating microbial physiology using synthetic riboregulators
    • doi: 10.1073/pnas.1009747107; pmid: 20713708
    • J. M. Callura, D. J. Dwyer, F. J. Isaacs, C. R. Cantor J. J. Collins, Tracking, tuning, and terminating microbial physiology using synthetic riboregulators. Proc. Natl. Acad. Sci. U.S.A. 107, 15898-15903 (2010). doi: 10.1073/pnas.1009747107; pmid: 20713708
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 15898-15903
    • Callura, J.M.1    Dwyer, D.J.2    Isaacs, F.J.3    Cantor, C.R.4    Collins, J.J.5
  • 12
    • 34447505900 scopus 로고    scopus 로고
    • A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells
    • doi: 10.1016/j.cell.2007.05.045; pmid: 17662949
    • T. L. Deans, C. R. Cantor, J. J. Collins, A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell 130, 363-372 (2007). doi: 10.1016/j.cell.2007.05.045; pmid: 17662949
    • (2007) Cell , vol.130 , pp. 363-372
    • Deans, T.L.1    Cantor, C.R.2    Collins, J.J.3
  • 13
    • 2942614884 scopus 로고    scopus 로고
    • Programmable cells: Interfacing natural and engineered gene networks
    • doi: 10.1073/pnas.0402940101; pmid: 15159530
    • H. Kobayashi et al., Programmable cells: Interfacing natural and engineered gene networks. Proc. Natl. Acad. Sci. U.S.A. 101, 8414-8419 (2004). doi: 10.1073/pnas.0402940101; pmid: 15159530
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 8414-8419
    • Kobayashi, H.1
  • 14
    • 84856790663 scopus 로고    scopus 로고
    • Synthetic biology: Advancing biological frontiers by building synthetic systems
    • doi: 10.1186/gb-2012-13-2-240; pmid: 22348749
    • Y. Y. Chen, K. E. Galloway, C. D. Smolke, Synthetic biology: Advancing biological frontiers by building synthetic systems. Genome Biol. 13, 240 (2012). doi: 10.1186/gb-2012-13-2-240; pmid: 22348749
    • (2012) Genome Biol. , vol.13 , pp. 240
    • Chen, Y.Y.1    Galloway, K.E.2    Smolke, C.D.3
  • 15
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • doi: 10.1016/S0092-8674(00)81683-9; pmid: 10647931
    • D. Hanahan, R. A. Weinberg, The hallmarks of cancer. Cell 100, 57-70 (2000). doi: 10.1016/S0092-8674(00)81683-9; pmid: 10647931
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 16
    • 0033435103 scopus 로고    scopus 로고
    • Signalling networks that cause cancer
    • doi: 10.1016/S0962-8924(99)01668-2; pmid: 10611683
    • F. McCormick, Signalling networks that cause cancer. Trends Cell Biol. 9, M53-M56 (1999). doi: 10.1016/S0962-8924(99)01668-2; pmid: 10611683
    • (1999) Trends Cell Biol. , vol.9
    • McCormick, F.1
  • 17
    • 0034923514 scopus 로고    scopus 로고
    • Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles
    • doi: 10.1146/annurev.biochem.70.1.703; pmid: 11395421
    • H. G. Dohlman, J. W. Thorner, Regulation of G protein-initiated signal transduction in yeast: Paradigms and principles. Annu. Rev. Biochem. 70, 703-754 (2001). doi: 10.1146/annurev.biochem.70.1.703; pmid: 11395421
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 703-754
    • Dohlman, H.G.1    Thorner, J.W.2
  • 18
    • 0033647489 scopus 로고    scopus 로고
    • Pheromone response, mating and cell biology
    • doi: 10.1016/S1369-5274(00)00143-0; pmid: 11121776
    • E. A. Elion, Pheromone response, mating and cell biology. Curr. Opin. Microbiol. 3, 573-581 (2000). doi: 10.1016/S1369-5274(00)00143-0; pmid: 11121776
    • (2000) Curr. Opin. Microbiol. , vol.3 , pp. 573-581
    • Elion, E.A.1
  • 19
    • 40849100220 scopus 로고    scopus 로고
    • Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics
    • doi: 10.1126/science.1151153; pmid: 18339942
    • C. J. Bashor, N. C. Helman, S. Yan, W. A. Lim, Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics. Science 319, 1539-1543 (2008). doi: 10.1126/science.1151153; pmid: 18339942
    • (2008) Science , vol.319 , pp. 1539-1543
    • Bashor, C.J.1    Helman, N.C.2    Yan, S.3    Lim, W.A.4
  • 20
    • 34047258309 scopus 로고    scopus 로고
    • Positive-feedback loops as a flexible biological module
    • doi: 10.1016/j.cub.2007.03.016; pmid: 17398098
    • N. T. Ingolia, A. W. Murray, Positive-feedback loops as a flexible biological module. Curr. Biol. 17, 668-677 (2007). doi: 10.1016/j.cub.2007.03. 016; pmid: 17398098
    • (2007) Curr. Biol. , vol.17 , pp. 668-677
    • Ingolia, N.T.1    Murray, A.W.2
  • 21
    • 0037436155 scopus 로고    scopus 로고
    • Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms
    • doi: 10.1126/science.1076979; pmid: 12511654
    • S. H. Park, A. Zarrinpar, W. A. Lim, Rewiring MAP kinase pathways using alternative scaffold assembly mechanisms. Science 299, 1061-1064 (2003). doi: 10.1126/science.1076979; pmid: 12511654
    • (2003) Science , vol.299 , pp. 1061-1064
    • Park, S.H.1    Zarrinpar, A.2    Lim, W.A.3
  • 22
    • 33847355217 scopus 로고    scopus 로고
    • Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate
    • doi: 10.1038/ncb1543; pmid: 17310240
    • S. D. Santos, P. J. Verveer, P. I. Bastiaens, Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate. Nat. Cell Biol. 9, 324-330 (2007). doi: 10.1038/ncb1543; pmid: 17310240
    • (2007) Nat. Cell Biol. , vol.9 , pp. 324-330
    • Santos, S.D.1    Verveer, P.J.2    Bastiaens, P.I.3
  • 23
    • 84887426619 scopus 로고    scopus 로고
    • Structural properties of the MAPK pathway topologies in PC12 cells
    • doi: 10.1007/s00285-012-0606-x
    • E. Franco, F. Blanchini, Structural properties of the MAPK pathway topologies in PC12 cells. J. Math. Biol. (2012). doi: 10.1007/s00285-012-0606-x
    • (2012) J. Math. Biol.
    • Franco, E.1    Blanchini, F.2
  • 24
    • 35448990907 scopus 로고    scopus 로고
    • A modular and extensible RNA-based gene-regulatory platform for engineering cellular function
    • doi: 10.1073/pnas.0703961104; pmid: 17709748
    • M. N. Win, C. D. Smolke, A modular and extensible RNA-based gene-regulatory platform for engineering cellular function. Proc. Natl. Acad. Sci. U.S.A. 104, 14283-14288 (2007). doi: 10.1073/pnas.0703961104; pmid: 17709748
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 14283-14288
    • Win, M.N.1    Smolke, C.D.2
  • 25
    • 84978771300 scopus 로고    scopus 로고
    • The Carter Center Mental Health Program: Addressing the public health crisis in the field of mental health through policy change and stigma reduction
    • pmid: 16539803
    • R. G. Palpant, R. Steimnitz, T. H. Bornemann, K. Hawkins, The Carter Center Mental Health Program: Addressing the public health crisis in the field of mental health through policy change and stigma reduction. Prev. Chronic Dis. 3, A62 (2006). pmid: 16539803
    • (2006) Prev. Chronic Dis. , vol.3
    • Palpant, R.G.1    Steimnitz, R.2    Bornemann, T.H.3    Hawkins, K.4
  • 26
    • 33746635479 scopus 로고    scopus 로고
    • Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae
    • doi: 10.1073/pnas.0604078103; pmid: 16847257
    • M. Osterberg et al., Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. U.S.A. 103, 11148-11153 (2006). doi: 10.1073/pnas.0604078103; pmid: 16847257
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 11148-11153
    • Osterberg, M.1
  • 27
    • 73149111973 scopus 로고    scopus 로고
    • Quantitative effect of scaffold abundance on signal propagation
    • doi: 10.1038/msb.2009.73; pmid: 19888208
    • S. A. Chapman, A. R. Asthagiri, Quantitative effect of scaffold abundance on signal propagation. Mol. Syst. Biol. 5, 313 (2009). doi: 10.1038/msb.2009.73; pmid: 19888208
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 313
    • Chapman, S.A.1    Asthagiri, A.R.2
  • 28
    • 16644373292 scopus 로고    scopus 로고
    • Noise minimization in eukaryotic gene expression
    • doi: 10.1371/journal.pbio.0020137; pmid: 15124029
    • H. B. Fraser, A. E. Hirsh, G. Giaever, J. Kumm, M. B. Eisen, Noise minimization in eukaryotic gene expression. PLoS Biol. 2, e137 (2004). doi: 10.1371/journal.pbio.0020137; pmid: 15124029
    • (2004) PLoS Biol. , vol.2
    • Fraser, H.B.1    Hirsh, A.E.2    Giaever, G.3    Kumm, J.4    Eisen, M.B.5
  • 29
    • 4444322221 scopus 로고    scopus 로고
    • Robustness properties of circadian clock architectures
    • doi: 10.1073/pnas.0401463101; pmid: 15340155
    • J. Stelling, E. D. Gilles, F. J. Doyle 3rd, Robustness properties of circadian clock architectures. Proc. Natl. Acad. Sci. U.S.A. 101, 13210-13215 (2004). doi: 10.1073/pnas.0401463101; pmid: 15340155
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 13210-13215
    • Stelling, J.1    Gilles, E.D.2    Doyle III, F.J.3
  • 30
    • 4544346660 scopus 로고    scopus 로고
    • Robustness of cellular functions
    • doi: 10.1016/j.cell.2004.09.008; pmid: 15369668
    • J. Stelling, U. Sauer, Z. Szallasi, F. J. Doyle 3rd, J. Doyle, Robustness of cellular functions. Cell 118, 675-685 (2004). doi: 10.1016/j.cell.2004.09. 008; pmid: 15369668
    • (2004) Cell , vol.118 , pp. 675-685
    • Stelling, J.1    Sauer, U.2    Szallasi, Z.3    Doyle III, F.J.4    Doyle, J.5
  • 31
    • 0037136555 scopus 로고    scopus 로고
    • Robustness of the BMP morphogen gradient in Drosophila embryonic patterning
    • doi: 10.1038/nature01061; pmid: 12239569
    • A. Eldar et al., Robustness of the BMP morphogen gradient in Drosophila embryonic patterning. Nature 419, 304-308 (2002). doi: 10.1038/nature01061; pmid: 12239569
    • (2002) Nature , vol.419 , pp. 304-308
    • Eldar, A.1
  • 32
    • 77957263267 scopus 로고    scopus 로고
    • Stabilizing patterning in the Drosophila segment polarity network by selecting models in silico
    • doi: 10.1016/j.biosystems.2010.07.014; pmid: 20655356
    • G. Stoll, M. Bischofberger, J. Rougemont, F. Naef, Stabilizing patterning in the Drosophila segment polarity network by selecting models in silico. Biosystems 102, 3-10 (2010). doi: 10.1016/j.biosystems.2010.07.014; pmid: 20655356
    • (2010) Biosystems , vol.102 , pp. 3-10
    • Stoll, G.1    Bischofberger, M.2    Rougemont, J.3    Naef, F.4
  • 33
    • 78650929625 scopus 로고    scopus 로고
    • Tunable signal processing in synthetic MAP kinase cascades
    • doi: 10.1016/j.cell.2010.12.014; pmid: 21215374
    • E. C. O'Shaughnessy, S. Palani, J. J. Collins, C. A. Sarkar, Tunable signal processing in synthetic MAP kinase cascades. Cell 144, 119-131 (2011). doi: 10.1016/j.cell.2010.12.014; pmid: 21215374
    • (2011) Cell , vol.144 , pp. 119-131
    • O'Shaughnessy, E.C.1    Palani, S.2    Collins, J.J.3    Sarkar, C.A.4
  • 34
    • 84155179185 scopus 로고    scopus 로고
    • Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range
    • doi: 10.1073/pnas.1004042108; pmid: 22114196
    • T. M. Thomson et al., Scaffold number in yeast signaling system sets tradeoff between system output and dynamic range. Proc. Natl. Acad. Sci. U.S.A. 108, 20265-20270 (2011). doi: 10.1073/pnas.1004042108; pmid: 22114196
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 20265-20270
    • Thomson, T.M.1
  • 35
    • 84869070585 scopus 로고    scopus 로고
    • A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity
    • doi: 10.1093/nar/gks636; pmid: 22810204
    • J. C. Liang, A. L. Chang, A. B. Kennedy, C. D. Smolke, A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity. Nucleic Acids Res. 40, e154 (2012). doi: 10.1093/nar/gks636; pmid: 22810204
    • (2012) Nucleic Acids Res. , vol.40
    • Liang, J.C.1    Chang, A.L.2    Kennedy, A.B.3    Smolke, C.D.4
  • 36
    • 0034212551 scopus 로고    scopus 로고
    • Engineering stability in gene networks by autoregulation
    • doi: 10.1038/35014651; pmid: 10850721
    • A. Becskei, L. Serrano, Engineering stability in gene networks by autoregulation. Nature 405, 590-593 (2000). doi: 10.1038/35014651; pmid: 10850721
    • (2000) Nature , vol.405 , pp. 590-593
    • Becskei, A.1    Serrano, L.2
  • 37
    • 66249084560 scopus 로고    scopus 로고
    • Design principles for riboswitch function
    • doi: 10.1371/journal.pcbi.1000363; pmid: 19381267
    • C. L. Beisel, C. D. Smolke, Design principles for riboswitch function. PLOS Comput. Biol. 5, e1000363 (2009). doi: 10.1371/journal.pcbi.1000363; pmid: 19381267
    • (2009) PLOS Comput. Biol. , vol.5
    • Beisel, C.L.1    Smolke, C.D.2
  • 38
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • doi: 10.1016/0092-8674(95)90401-8; pmid: 7834738
    • C. J. Marshall, Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 80, 179-185 (1995). doi: 10.1016/0092-8674(95)90401-8; pmid: 7834738
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 39
    • 0034878782 scopus 로고    scopus 로고
    • Differential regulation of the two principal Runx2/Cbfa1 N-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype
    • doi: 10.1210/en.142.9.4026; pmid: 11517182
    • C. Banerjee et al., Differential regulation of the two principal Runx2/Cbfa1 N-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype. Endocrinology 142, 4026-4039 (2001). doi: 10.1210/en.142.9.4026; pmid: 11517182
    • (2001) Endocrinology , vol.142 , pp. 4026-4039
    • Banerjee, C.1
  • 40
    • 75649098860 scopus 로고    scopus 로고
    • Alternative splicing and gene duplication differentially shaped the regulation of isochorismate synthase in Populus and Arabidopsis
    • doi: 10.1073/pnas.0906869106; pmid: 19996170
    • Y. Yuan et al., Alternative splicing and gene duplication differentially shaped the regulation of isochorismate synthase in Populus and Arabidopsis. Proc. Natl. Acad. Sci. U.S.A. 106, 22020-22025 (2009). doi: 10.1073/pnas. 0906869106; pmid: 19996170
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 22020-22025
    • Yuan, Y.1
  • 41
    • 0037047611 scopus 로고    scopus 로고
    • MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network
    • doi: 10.1126/science.1068873; pmid: 12169734
    • U. S. Bhalla, P. T. Ram, R. Iyengar, MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network. Science 297, 1018-1023 (2002). doi: 10.1126/science.1068873; pmid: 12169734
    • (2002) Science , vol.297 , pp. 1018-1023
    • Bhalla, U.S.1    Ram, P.T.2    Iyengar, R.3
  • 42
    • 14244255014 scopus 로고    scopus 로고
    • Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival
    • doi: 10.1074/jbc.M411200200; pmid: 15590693
    • W. Wu, T. Pew, M. Zou, D. Pang, S. D. Conzen, Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. J. Biol. Chem. 280, 4117-4124 (2005). doi: 10.1074/jbc.M411200200; pmid: 15590693
    • (2005) J. Biol. Chem. , vol.280 , pp. 4117-4124
    • Wu, W.1    Pew, T.2    Zou, M.3    Pang, D.4    Conzen, S.D.5
  • 43
    • 1642315292 scopus 로고    scopus 로고
    • Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells
    • doi: 10.1158/0008-5472.CAN-03-2546; pmid: 14996737
    • W. Wu et al., Microarray analysis reveals glucocorticoid-regulated survival genes that are associated with inhibition of apoptosis in breast epithelial cells. Cancer Res. 64, 1757-1764 (2004). doi: 10.1158/0008-5472.CAN- 03-2546; pmid: 14996737
    • (2004) Cancer Res. , vol.64 , pp. 1757-1764
    • Wu, W.1
  • 44
    • 0032877013 scopus 로고    scopus 로고
    • Human DU145 prostate cancer cells overexpressing mitogen-activated protein kinase phosphatase-1 are resistant to Fas ligand-induced mitochondrial perturbations and cellular apoptosis
    • doi: 10.1023/A:1006980326855; pmid: 10544965
    • S. Srikanth, C. C. Franklin, R. C. Duke, R. S. Kraft, Human DU145 prostate cancer cells overexpressing mitogen-activated protein kinase phosphatase-1 are resistant to Fas ligand-induced mitochondrial perturbations and cellular apoptosis. Mol. Cell. Biochem. 199, 169-178 (1999). doi: 10.1023/A:1006980326855; pmid: 10544965
    • (1999) Mol. Cell. Biochem. , vol.199 , pp. 169-178
    • Srikanth, S.1    Franklin, C.C.2    Duke, R.C.3    Kraft, R.S.4
  • 45
    • 33745092405 scopus 로고    scopus 로고
    • Biochemical and biological characterization of a neuroendocrine- associated phosphatase
    • doi: 10.1111/j.1471-4159.2006.03852.x; pmid: 16805799
    • J. Y. Wang, C. H. Lin, C. H. Yang, T. H. Tan, Y. R. Chen, Biochemical and biological characterization of a neuroendocrine-associated phosphatase. J. Neurochem. 98, 89-101 (2006). doi: 10.1111/j.1471-4159.2006.03852.x; pmid: 16805799
    • (2006) J. Neurochem. , vol.98 , pp. 89-101
    • Wang, J.Y.1    Lin, C.H.2    Yang, C.H.3    Tan, T.H.4    Chen, Y.R.5
  • 46
    • 0025971103 scopus 로고
    • Assay of yeast mating reaction
    • doi: 10.1016/0076-6879 (91)94008-Z; pmid: 2005823
    • G. F. Sprague Jr., Assay of yeast mating reaction. Methods Enzymol. 194, 77-93 (1991). doi: 10.1016/0076-6879 (91)94008-Z; pmid: 2005823
    • (1991) Methods Enzymol. , vol.194 , pp. 77-93
    • Sprague Jr., G.F.1
  • 47
    • 0029790351 scopus 로고    scopus 로고
    • Ultrasensitivity in the mitogen-activated protein kinase cascade
    • doi: 10.1073/pnas.93.19.10078; pmid: 8816754
    • C. Y. Huang, J. E. Ferrell Jr., Ultrasensitivity in the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. U.S.A. 93, 10078-10083 (1996). doi: 10.1073/pnas.93.19.10078; pmid: 8816754
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 10078-10083
    • Huang, C.Y.1    Ferrell Jr., J.E.2
  • 48
    • 1242274449 scopus 로고    scopus 로고
    • Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems
    • doi: 10.1073/pnas.0308265100; pmid: 14766974
    • D. Angeli, J. E. Ferrell Jr., E. D. Sontag, Detection of multistability, bifurcations, and hysteresis in a large class of biological positive-feedback systems. Proc. Natl. Acad. Sci. U.S.A. 101, 1822-1827 (2004). doi: 10.1073/pnas.0308265100; pmid: 14766974
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 1822-1827
    • Angeli, D.1    Ferrell Jr., J.E.2    Sontag, E.D.3
  • 49
    • 14844318077 scopus 로고    scopus 로고
    • When kinases meet mathematics: The systems biology of MAPK signalling
    • doi: 10.1016/j.febslet.2005.02.002; pmid: 15763569
    • W. Kolch, M. Calder, D. Gilbert, When kinases meet mathematics: The systems biology of MAPK signalling. FEBS Lett. 579, 1891-1895 (2005). doi: 10.1016/j.febslet.2005.02.002; pmid: 15763569
    • (2005) FEBS Lett. , vol.579 , pp. 1891-1895
    • Kolch, W.1    Calder, M.2    Gilbert, D.3
  • 50
    • 0030820725 scopus 로고    scopus 로고
    • Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae
    • doi: 10.1101/gad.11.13.1690; pmid: 9224718
    • X. L. Zhan, R. J. Deschenes, K. L. Guan, Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae. Genes Dev. 11, 1690-1702 (1997). doi: 10.1101/gad.11.13.1690; pmid: 9224718
    • (1997) Genes Dev. , vol.11 , pp. 1690-1702
    • Zhan, X.L.1    Deschenes, R.J.2    Guan, K.L.3
  • 51
    • 3342900058 scopus 로고    scopus 로고
    • Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes
    • doi: 10.1038/sj.emboj.7600250; pmid: 15192700
    • J. Andersson, D. M. Simpson, M. Qi, Y. Wang, E. A. Elion, Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J. 23, 2564-2576 (2004). doi: 10.1038/sj.emboj.7600250; pmid: 15192700
    • (2004) EMBO J. , vol.23 , pp. 2564-2576
    • Andersson, J.1    Simpson, D.M.2    Qi, M.3    Wang, Y.4    Elion, E.A.5
  • 52
    • 4444272353 scopus 로고    scopus 로고
    • Modelling the dynamics of the yeast pheromone pathway
    • doi: 10.1002/yea.1122; pmid: 15300679
    • B. Kofahl, E. Klipp, Modelling the dynamics of the yeast pheromone pathway. Yeast 21, 831-850 (2004). doi: 10.1002/yea.1122; pmid: 15300679
    • (2004) Yeast , vol.21 , pp. 831-850
    • Kofahl, B.1    Klipp, E.2


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