Sesamin ameliorates arterial dysfunction in spontaneously hypertensive rats via downregulation of NADPH oxidase subunits and upregulation of eNOS expression

Acta Pharmacologica Sinica

Volumn 34, Issue 7, 2013, Pages 912-920

  Zhang, Jun Xiu ^a   Yang, Jie Ren ^a   Chen, Guo Xiang ^a   Tang, Li Juan ^a   Li, Wen Xing ^a   Yang, Hui ^a   Kong, Xiang ^a  

^a WANNAN MEDICAL COLLEGE   (China)

Author keywords

ACh; aorta; endothelium; eNOS; malondialdehyde; NADPH oxidase; nitroprusside; sesamin; spontaneously hypertensive rat; vasorelaxation

Indexed keywords

3 NITROTYROSINE; ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MALONALDEHYDE; NITROPRUSSIDE SODIUM; PROTEIN P22; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SESAMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DILATATION; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL REACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSECTION; DOWN REGULATION; DRUG EFFECT; DRUG STRUCTURE; ENZYME INACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HYPERTENSION; IMMUNOHISTOCHEMISTRY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; THORACIC AORTA; UPREGULATION; VASCULAR RING; WESTERN BLOTTING;

ANIMALS; AORTA, THORACIC; DIOXOLES; DOWN-REGULATION; HYPERTENSION; LIGNANS; MALE; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE III; ORGAN CULTURE TECHNIQUES; PROTEIN SUBUNITS; RANDOM ALLOCATION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; UP-REGULATION;

EID: 84881400823     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.1     Document Type: Article

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