-
2
-
-
43549098268
-
Calcium cycling and signaling in cardiac myocytes
-
DOI 10.1146/annurev.physiol.70.113006.100455
-
Bers DM (2008) Calcium cycling and signaling in cardiac myocytes. Annu Rev Physiol 70:23-49 (Pubitemid 351738170)
-
(2008)
Annual Review of Physiology
, vol.70
, pp. 23-49
-
-
Bers, D.M.1
-
3
-
-
84862825070
-
2+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility
-
10.1161/CIRCRESAHA.111.264028 1:CAS:528:DC%2BC38XjtV2nur4%3D 22302787
-
2+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility. Circ Res 110:669-674
-
(2012)
Circ Res
, vol.110
, pp. 669-674
-
-
Makarewich, C.A.1
Correll, R.N.2
Gao, H.3
Zhang, H.4
Yang, B.5
Berretta, R.M.6
Rizzo, V.7
Molkentin, J.D.8
Houser, S.R.9
-
4
-
-
33644641253
-
2+ signaling in cardiac myocyte excitation-transcription coupling
-
DOI 10.1172/JCI27374
-
2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest 116:675-682 (Pubitemid 43326876)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.3
, pp. 675-682
-
-
Wu, X.1
Zhang, T.2
Bossuyt, J.3
Li, X.4
McKinsey, T.A.5
Dedman, J.R.6
Olson, E.N.7
Chen, J.8
Brown, J.H.9
Bers, D.M.10
-
6
-
-
0027052523
-
Calmodulin structure refined at 1.7 A resolution
-
DOI 10.1016/0022-2836(92)90324-D
-
Chattopadhyaya R, Meador WE, Means AR, Quiocho FA (1992) Calmodulin structure refined at 1.7 A resolution. J Mol Biol 228:1177-1192 (Pubitemid 23018499)
-
(1992)
Journal of Molecular Biology
, vol.228
, Issue.4
, pp. 1177-1192
-
-
Chattopadhyaya, R.1
Meador, W.E.2
Means, A.R.3
Quiocho, F.A.4
-
7
-
-
33744955173
-
2+-dependent switching in a calmodulin-IQ domain complex
-
DOI 10.1021/bi052533w
-
2+- dependent switching in a calmodulin-IQ domain complex. Biochemistry 45:6987-6995 (Pubitemid 43856683)
-
(2006)
Biochemistry
, vol.45
, Issue.22
, pp. 6987-6995
-
-
Black, D.J.1
Leonard, J.2
Persechini, A.3
-
8
-
-
0347379936
-
A New Role for IQ Motif Proteins in Regulating Calmodulin Function
-
DOI 10.1074/jbc.C300372200
-
Putkey JA, Kleerekoper Q, Gaertner TR, Waxham MN (2003) A new role for IQ motif proteins in regulating calmodulin function. J Biol Chem 278:49667-49670 (Pubitemid 37548796)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.50
, pp. 49667-49670
-
-
Putkey, J.A.1
Kleerekoper, Q.2
Gaertner, T.R.3
Waxham, M.N.4
-
9
-
-
84862128507
-
Measuring the kinetics of calcium binding proteins with flash photolysis
-
10.1016/j.bbagen.2011.09.012 1:CAS:528:DC%2BC38Xot12jsLc%3D 22001612
-
Faas GC, Mody I (2012) Measuring the kinetics of calcium binding proteins with flash photolysis. Biochim Biophys Acta 1820:1195-1204
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 1195-1204
-
-
Faas, G.C.1
Mody, I.2
-
10
-
-
0037155689
-
Calmodulin in action: Diversity in target recognition and activation mechanisms
-
DOI 10.1016/S0092-8674(02)00682-7
-
Hoeflich KP, Ikura M (2002) Calmodulin in action: diversity in target recognition and activation mechanisms. Cell 108:739-742 (Pubitemid 34327526)
-
(2002)
Cell
, vol.108
, Issue.6
, pp. 739-742
-
-
Hoeflich, K.P.1
Ikura, M.2
-
11
-
-
81255143982
-
2+-bound forms of the calmodulin C-lobe direct the N-lobe to different binding sites
-
10.1021/bi201300v 1:CAS:528:DC%2BC3MXhtlWjtL%2FP 21999573
-
2+-bound forms of the calmodulin C-lobe direct the N-lobe to different binding sites. Biochemistry 50:10061-10068
-
(2011)
Biochemistry
, vol.50
, pp. 10061-10068
-
-
Black, D.J.1
Persechini, A.2
-
12
-
-
80054735073
-
Probing calmodulin protein-protein interactions using high-content protein arrays
-
10.1007/978-1-61779-286-1-20 21901608
-
O'Connell DJ, Bauer M, Linse S, Cahill DJ (2011) Probing calmodulin protein-protein interactions using high-content protein arrays. Methods Mol Biol 785:289-303
-
(2011)
Methods Mol Biol
, vol.785
, pp. 289-303
-
-
O'Connell, D.J.1
Bauer, M.2
Linse, S.3
Cahill, D.J.4
-
13
-
-
0028921581
-
Calmodulin-binding domains: Just two faced or multi-faceted?
-
10.1016/S0968-0004(00)88949-5 1:CAS:528:DyaK2MXjtlanu7k%3D 7878743
-
James P, Vorherr T, Carafoli E (1995) Calmodulin-binding domains: just two faced or multi-faceted? Trends Biochem Sci 20:38-42
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 38-42
-
-
James, P.1
Vorherr, T.2
Carafoli, E.3
-
14
-
-
0028506122
-
Calmodulin: A versatile calcium mediator protein
-
10.1139/o94-049 1:CAS:528:DyaK2MXkslOgu74%3D 7605608
-
Vogel HJ (1994) Calmodulin: a versatile calcium mediator protein. Biochem Cell Biol 72:357-376
-
(1994)
Biochem Cell Biol
, vol.72
, pp. 357-376
-
-
Vogel, H.J.1
-
15
-
-
71549152825
-
The IQ domains in neuromodulin and PEP19 represent two major functional classes
-
10.1021/bi9014874 1:CAS:528:DC%2BD1MXhsVWrtb3O 19877718
-
Black DJ, LaMartina D, Persechini A (2009) The IQ domains in neuromodulin and PEP19 represent two major functional classes. Biochemistry 48:11766-11772
-
(2009)
Biochemistry
, vol.48
, pp. 11766-11772
-
-
Black, D.J.1
Lamartina, D.2
Persechini, A.3
-
16
-
-
0028222312
-
Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B
-
DOI 10.1021/bi00188a015
-
Stemmer PM, Klee CB (1994) Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B. Biochemistry 33:6859-6866 (Pubitemid 24190809)
-
(1994)
Biochemistry
, vol.33
, Issue.22
, pp. 6859-6866
-
-
Stemmer, P.M.1
Klee, C.B.2
-
18
-
-
0035827585
-
Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor)
-
10.1074/jbc.M010771200 1:CAS:528:DC%2BD3MXktlKnsLo%3D 11274202
-
Balshaw DM, Xu L, Yamaguchi N, Pasek DA, Meissner G (2001) Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor). J Biol Chem 276:20144-20153
-
(2001)
J Biol Chem
, vol.276
, pp. 20144-20153
-
-
Balshaw, D.M.1
Xu, L.2
Yamaguchi, N.3
Pasek, D.A.4
Meissner, G.5
-
20
-
-
0036702526
-
Calcium, calmodulin, and calcium-calmodulin kinase II: Heartbeat to heartbeat and beyond
-
DOI 10.1006/jmcc.2002.2038
-
Maier LS, Bers DM (2002) Calcium, calmodulin, and calcium-calmodulin kinase II: heartbeat to heartbeat and beyond. J Mol Cell Cardiol 34:919-939 (Pubitemid 35316141)
-
(2002)
Journal of Molecular and Cellular Cardiology
, vol.34
, Issue.8
, pp. 919-939
-
-
Maier, L.S.1
Bers, D.M.2
-
21
-
-
79958151890
-
2+-dependent calmodulin-target binding by Fura-2 and CFP and YFP FRET imaging in living cells
-
10.1021/bi200287x 1:CAS:528:DC%2BC3MXlsFWntb4%3D 21517110
-
2+-dependent calmodulin-target binding by Fura-2 and CFP and YFP FRET imaging in living cells. Biochemistry 50:4685-4696
-
(2011)
Biochemistry
, vol.50
, pp. 4685-4696
-
-
Mori, M.X.1
Imai, Y.2
Itsuki, K.3
Inoue, R.4
-
22
-
-
80455174814
-
FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel
-
10.1016/j.bpj.2011.09.030 1:CAS:528:DC%2BC3MXhsVaqs7zF 22067155
-
Guo T, Fruen BR, Nitu FR, Nguyen TD, Yang Y, Cornea RL, Bers DM (2011) FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel. Biophys J 101:2170-2177
-
(2011)
Biophys J
, vol.101
, pp. 2170-2177
-
-
Guo, T.1
Fruen, B.R.2
Nitu, F.R.3
Nguyen, T.D.4
Yang, Y.5
Cornea, R.L.6
Bers, D.M.7
-
23
-
-
84873408824
-
Binding of RyR2 unzipping peptide in cardiomyocytes activates RyR2 and reciprocally inhibits calmodulin binding
-
10.1161/CIRCRESAHA.111.300290 1:CAS:528:DC%2BC3sXhslWgsrw%3D 23233753
-
Oda T, Yang Y, Nitu FR, Svensson B, Lu X, Fruen BR, Cornea RL, Bers DM (2013) Binding of RyR2 unzipping peptide in cardiomyocytes activates RyR2 and reciprocally inhibits calmodulin binding. Circ Res 112:487-497
-
(2013)
Circ Res
, vol.112
, pp. 487-497
-
-
Oda, T.1
Yang, Y.2
Nitu, F.R.3
Svensson, B.4
Lu, X.5
Fruen, B.R.6
Cornea, R.L.7
Bers, D.M.8
-
24
-
-
33748436655
-
Dynamic changes in free Ca-calmodulin levels in adult cardiac myocytes
-
DOI 10.1016/j.yjmcc.2006.04.020, PII S0022282806005591
-
Maier LS, Ziolo MT, Bossuyt J, Persechini A, Mestril R, Bers DM (2006) Dynamic changes in free Ca-calmodulin levels in adult cardiac myocytes. J Mol Cell Cardiol 41:451-458 (Pubitemid 44344277)
-
(2006)
Journal of Molecular and Cellular Cardiology
, vol.41
, Issue.3
, pp. 451-458
-
-
Maier, L.S.1
Ziolo, M.T.2
Bossuyt, J.3
Persechini, A.4
Mestril, R.5
Bers, D.M.6
-
25
-
-
0036138931
-
Calmodulin is a limiting factor in the cell
-
DOI 10.1016/S1050-1738(01)00144-X, PII S105017380100144X
-
Persechini A, Stemmer PM (2002) Calmodulin is a limiting factor in the cell. Trends Cardiovasc Med 12:32-37 (Pubitemid 34048708)
-
(2002)
Trends in Cardiovascular Medicine
, vol.12
, Issue.1
, pp. 32-37
-
-
Persechini, A.1
Stemmer, P.M.2
-
26
-
-
33847171883
-
Free and bound intracellular calmodulin measurements in cardiac myocytes
-
DOI 10.1016/j.ceca.2006.07.011, PII S0143416006001618
-
Wu X, Bers DM (2007) Free and bound intracellular calmodulin measurements in cardiac myocytes. Cell Calcium 41:353-364 (Pubitemid 46277393)
-
(2007)
Cell Calcium
, vol.41
, Issue.4
, pp. 353-364
-
-
Wu, X.1
Bers, D.M.2
-
27
-
-
0025082249
-
Ca current facilitation during postrest recovery depends on Ca entry
-
1:CAS:528:DyaK3cXlvVyrtrg%3D 2168683
-
Hryshko LV, Bers DM (1990) Ca current facilitation during postrest recovery depends on Ca entry. Am J Physiol 259:H951-961
-
(1990)
Am J Physiol
, vol.259
, pp. 951-961
-
-
Hryshko, L.V.1
Bers, D.M.2
-
28
-
-
33747881612
-
2+ Channel Facilitation Mediated by Phosphorylation of the β Subunit by CaMKII
-
DOI 10.1016/j.molcel.2006.07.006, PII S1097276506004837
-
2+ channel facilitation mediated by phosphorylation of the beta subunit by CaMKII. Mol Cell 23:641-650 (Pubitemid 44292555)
-
(2006)
Molecular Cell
, vol.23
, Issue.5
, pp. 641-650
-
-
Grueter, C.E.1
Abiria, S.A.2
Dzhura, I.3
Wu, Y.4
Ham, A.-J.L.5
Mohler, P.J.6
Anderson, M.E.7
Colbran, R.J.8
-
31
-
-
0035910106
-
Calmodulin priming: Nuclear translocation of a calmodulin complex and the memory of prior neuronal activity
-
DOI 10.1073/pnas.211563998
-
Mermelstein PG, Deisseroth K, Dasgupta N, Isaksen AL, Tsien RW (2001) Calmodulin priming: nuclear translocation of a calmodulin complex and the memory of prior neuronal activity. Proc Natl Acad Sci 98:15342-15347 (Pubitemid 34014016)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.26
, pp. 15342-15347
-
-
Mermelstein, P.G.1
Deisseroth, K.2
Dasgupta, N.3
Isaksen, A.L.4
Tsien, R.W.5
-
33
-
-
12344252241
-
2+-dependent and -independent mechanisms of calmodulin nuclear translocation
-
DOI 10.1242/jcs.01510
-
2+-dependent and -independent mechanisms of calmodulin nuclear translocation. J Cell Sci 117:5923-5936 (Pubitemid 40123958)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.24
, pp. 5923-5936
-
-
Thorogate, R.1
Torok, K.2
-
34
-
-
0028210920
-
Decreased expression of calmodulin mRNA in human end-stage heart failure
-
DOI 10.1006/jmcc.1994.1011
-
Jeck CD, Zimmermann R, Schaper J, Schaper W (1994) Decreased expression of calmodulin mRNA in human end-stage heart failure. J Mol Cell Cardiol 26:99-107 (Pubitemid 24071724)
-
(1994)
Journal of Molecular and Cellular Cardiology
, vol.26
, Issue.1
, pp. 99-107
-
-
Jeck, C.D.1
Zimmermann, R.2
Schaper, J.3
Schaper, W.4
-
35
-
-
84857178202
-
Differences in MEF2 and NFAT transcriptional pathways according to human heart failure aetiology
-
10.1371/journal.pone.0030915 1:CAS:528:DC%2BC38Xjt1Sgu78%3D 22363514
-
Cortes R, Rivera M, Rosello-Lleti E, Martinez-Dolz L, Almenar L, Azorin I, Lago F, Gonzalez-Juanatey JR, Portoles M (2012) Differences in MEF2 and NFAT transcriptional pathways according to human heart failure aetiology. PLoS One 7:e30915
-
(2012)
PLoS One
, vol.7
, pp. 30915
-
-
Cortes, R.1
Rivera, M.2
Rosello-Lleti, E.3
Martinez-Dolz, L.4
Almenar, L.5
Azorin, I.6
Lago, F.7
Gonzalez-Juanatey, J.R.8
Portoles, M.9
-
37
-
-
77952743060
-
2+/calmodulin- dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytes
-
10.1016/j.bbrc.2010.04.129 1:CAS:528:DC%2BC3cXmslOns7o%3D 20433809
-
2+/calmodulin-dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytes. Biochem Biophys Res Commun 396:515-521
-
(2010)
Biochem Biophys Res Commun
, vol.396
, pp. 515-521
-
-
Gangopadhyay, J.P.1
Ikemoto, N.2
-
38
-
-
84855990580
-
2+ signaling in cardiac myocytes
-
10.1016/j.yjmcc.2011.06.005 1:CAS:528:DC%2BC38XhtFGhtr0%3D 21708171
-
2+ signaling in cardiac myocytes. J Mol Cell Cardiol 52:312-316
-
(2012)
J Mol Cell Cardiol
, vol.52
, pp. 312-316
-
-
Saucerman, J.J.1
Bers, D.M.2
-
40
-
-
0023261649
-
Calmodulin binding by calcineurin. Ligand-induced renaturation of protein immobilized on nitrocellulose
-
Hubbard MJ, Klee CB (1987) Calmodulin binding by calcineurin. Ligand-induced renaturation of protein immobilized on nitrocellulose. J Biol Chem 262:15062-15070 (Pubitemid 17160175)
-
(1987)
Journal of Biological Chemistry
, vol.262
, Issue.31
, pp. 15062-15070
-
-
Hubbard, M.J.1
Klee, C.B.2
-
41
-
-
0021023746
-
Regulation of cardiac sarcoplasmic reticulum calcium transport by calcium-calmodulin-dependent phosphorylation
-
Davis BA, Schwartz A, Samaha FJ, Kranias EG (1983) Regulation of cardiac sarcoplasmic reticulum calcium transport by calcium-calmodulin-dependent phosphorylation. J Biol Chem 258:13587-13591 (Pubitemid 14204561)
-
(1983)
Journal of Biological Chemistry
, vol.258
, Issue.22
, pp. 13587-13591
-
-
Davis, B.A.1
Schwartz, A.2
Samaha, F.J.3
Kranias, E.G.4
-
43
-
-
0031011418
-
2+-dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. A new class of fluorescent indicators
-
DOI 10.1074/jbc.272.20.13270
-
2+-dependent changes in the fluorescence emission of an indicator composed of two green fluorescent protein variants linked by a calmodulin-binding sequence. A new class of fluorescent indicators. J Biol Chem 272:13270-13274 (Pubitemid 27216756)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.20
, pp. 13270-13274
-
-
Romoser, V.A.1
Hinkle, P.M.2
Persechini, A.3
-
45
-
-
18144395838
-
Dominant affectors in the calmodulin network shape the time courses of target responses in the cell
-
DOI 10.1016/j.ceca.2005.02.001, PII S0143416005000370
-
Tran QK, Black DJ, Persechini A (2005) Dominant affectors in the calmodulin network shape the time courses of target responses in the cell. Cell Calcium 37:541-553 (Pubitemid 40613632)
-
(2005)
Cell Calcium
, vol.37
, Issue.6
, pp. 541-553
-
-
Tran, Q.-K.1
Black, D.J.2
Persechini, A.3
-
47
-
-
58149280497
-
2+ in cardiac myocytes
-
10.1529/biophysj.108.128728 1:CAS:528:DC%2BD1cXhtlOqtLjM 18689454
-
2+ in cardiac myocytes. Biophys J 95:4597-4612
-
(2008)
Biophys J
, vol.95
, pp. 4597-4612
-
-
Saucerman, J.J.1
Bers, D.M.2
-
48
-
-
10744227254
-
2+ signalling and gene expression
-
DOI 10.1113/jphysiol.2003.053579
-
2+ signalling and gene expression. J Physiol 554:309-320 (Pubitemid 38181346)
-
(2004)
Journal of Physiology
, vol.554
, Issue.2
, pp. 309-320
-
-
Tavi, P.1
Pikkarainen, S.2
Ronkainen, J.3
Niemela, P.4
Ilves, M.5
Weckstrom, M.6
Vuolteenaho, O.7
Bruton, J.8
Westerblad, H.9
Ruskoaho, H.10
-
50
-
-
67949121985
-
2+ channel
-
10.1161/CIRCRESAHA.109.199828 1:CAS:528:DC%2BD1MXns1Chtr4%3D 19478199
-
2+ channel. Circ Res 105:51-60
-
(2009)
Circ Res
, vol.105
, pp. 51-60
-
-
Tandan, S.1
Wang, Y.2
Wang, T.T.3
Jiang, N.4
Hall, D.D.5
Hell, J.W.6
Luo, X.7
Rothermel, B.A.8
Hill, J.A.9
-
51
-
-
80051981571
-
Cardiac calmodulin kinase: A potential target for drug design
-
10.2174/092986711796642409 1:CAS:528:DC%2BC3MXhtFSqu7rM 21774758
-
Banyasz T, Szentandrassy N, Toth A, Nanasi PP, Magyar J, Chen-Izu Y (2011) Cardiac calmodulin kinase: a potential target for drug design. Curr Med Chem 18:3707-3713
-
(2011)
Curr Med Chem
, vol.18
, pp. 3707-3713
-
-
Banyasz, T.1
Szentandrassy, N.2
Toth, A.3
Nanasi, P.P.4
Magyar, J.5
Chen-Izu, Y.6
-
53
-
-
79960108482
-
CaMKII in the cardiovascular system: Sensing redox states
-
10.1152/physrev.00018.2010 1:CAS:528:DC%2BC3MXhtFyjur%2FL 21742790
-
Erickson JR, He BJ, Grumbach IM, Anderson ME (2011) CaMKII in the cardiovascular system: sensing redox states. Physiol Rev 91:889-915
-
(2011)
Physiol Rev
, vol.91
, pp. 889-915
-
-
Erickson, J.R.1
He, B.J.2
Grumbach, I.M.3
Anderson, M.E.4
-
54
-
-
84876326824
-
The Ca-calmodulin dependent kinase II: A promising target for future antiarrhythmic therapies?
-
10.1016/j.yjmcc.2012.11.003 1:CAS:528:DC%2BC38XhvVekurjL 23159442
-
Fischer TH, Neef S, Maier LS (2013) The Ca-calmodulin dependent kinase II: a promising target for future antiarrhythmic therapies? J Mol Cell Cardiol 58:182-187
-
(2013)
J Mol Cell Cardiol
, vol.58
, pp. 182-187
-
-
Fischer, T.H.1
Neef, S.2
Maier, L.S.3
-
55
-
-
84859927880
-
2+/calmodulin-dependent protein kinase II (CaMKII) in the heart
-
10.1007/978-94-007-2888-2-30 1:CAS:528:DC%2BC38XhtlensbfE 22453965
-
2+/calmodulin-dependent protein kinase II (CaMKII) in the heart. Adv Exp Med Biol 740:685-702
-
(2012)
Adv Exp Med Biol
, vol.740
, pp. 685-702
-
-
Maier, L.S.1
-
56
-
-
84867796466
-
2+/calmodulin-dependent kinase II (CaMKII)
-
10.1161/CIRCULATIONAHA.112.124990 23091085
-
2+/calmodulin-dependent kinase II (CaMKII). Circulation 126:2125-2139
-
(2012)
Circulation
, vol.126
, pp. 2125-2139
-
-
Rokita, A.G.1
Anderson, M.E.2
-
57
-
-
79959963935
-
Is CaMKII a link between inflammation and hypertrophy in heart?
-
10.1007/s00109-011-0727-5 1:CAS:528:DC%2BC3MXmtl2lsbY%3D
-
Singh MV, Anderson ME (2011) Is CaMKII a link between inflammation and hypertrophy in heart? J Mol Med (Berl) 89:537-543
-
(2011)
J Mol Med (Berl)
, vol.89
, pp. 537-543
-
-
Singh, M.V.1
Anderson, M.E.2
-
58
-
-
84862296973
-
Calmodulin-dependent protein kinase II: Linking heart failure and arrhythmias
-
10.1161/CIRCRESAHA.111.243956 1:CAS:528:DC%2BC38XotFKiu7g%3D 22679140
-
Swaminathan PD, Purohit A, Hund TJ, Anderson ME (2012) Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias. Circ Res 110:1661-1677
-
(2012)
Circ Res
, vol.110
, pp. 1661-1677
-
-
Swaminathan, P.D.1
Purohit, A.2
Hund, T.J.3
Anderson, M.E.4
-
59
-
-
0345303850
-
2+/CaM- dependent protein kinase genes
-
DOI 10.1016/j.gene.2003.08.023
-
2+/CaM-dependent protein kinase genes. Gene 322:17-31 (Pubitemid 37485979)
-
(2003)
Gene
, vol.322
, Issue.1-2
, pp. 17-31
-
-
Tombes, R.M.1
Faison, M.O.2
Turbeville, J.M.3
-
60
-
-
0035997377
-
2+/calmodulin-dependent protein kinase II: The role of structure and autoregulation in cellular function
-
DOI 10.1146/annurev.biochem.71.110601.135410
-
2+/calmodulin-dependent protein kinase II: the role of structure and autoregulation in cellular function. Annu Rev Biochem 71:473-510 (Pubitemid 34800228)
-
(2002)
Annual Review of Biochemistry
, vol.71
, pp. 473-510
-
-
Hudmon, A.1
Schulman, H.2
-
62
-
-
77949272793
-
Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation
-
10.1038/nsmb.1751 1:CAS:528:DC%2BC3cXhs1Oks7c%3D 20139983
-
Chao LH, Pellicena P, Deindl S, Barclay LA, Schulman H, Kuriyan J (2010) Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Nat Struct Mol Biol 17:264-272
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 264-272
-
-
Chao, L.H.1
Pellicena, P.2
Deindl, S.3
Barclay, L.A.4
Schulman, H.5
Kuriyan, J.6
-
63
-
-
0032498172
-
2+ oscillations
-
DOI 10.1126/science.279.5348.227
-
2+ oscillations. Science 279:227-230 (Pubitemid 28103880)
-
(1998)
Science
, vol.279
, Issue.5348
, pp. 227-230
-
-
De Koninck, P.1
Schulman, H.2
-
64
-
-
79953795879
-
Conformational changes underlying calcium/calmodulin-dependent protein kinase II activation
-
10.1038/emboj.2011.40 1:CAS:528:DC%2BC3MXitlertro%3D 21343908
-
Hoffman L, Stein RA, Colbran RJ, McHaourab HS (2011) Conformational changes underlying calcium/calmodulin-dependent protein kinase II activation. EMBO J 30:1251-1262
-
(2011)
EMBO J
, vol.30
, pp. 1251-1262
-
-
Hoffman, L.1
Stein, R.A.2
Colbran, R.J.3
McHaourab, H.S.4
-
65
-
-
0023819289
-
2+/calmodulin-dependent protein kinase II. Identification of a regulatory autophosphorylation site adjacent to the inhibitory and calmodulin-binding domains
-
1:CAS:528:DyaL1cXmt1Gks7s%3D 3417668
-
2+/calmodulin-dependent protein kinase II. Identification of a regulatory autophosphorylation site adjacent to the inhibitory and calmodulin-binding domains. J Biol Chem 263:13486-13489
-
(1988)
J Biol Chem
, vol.263
, pp. 13486-13489
-
-
Schworer, C.M.1
Colbran, R.J.2
Keefer, J.R.3
Soderling, T.R.4
-
66
-
-
77955039883
-
Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation
-
10.1371/journal.pbio.1000426 20668654
-
Rellos P, Pike AC, Niesen FH, Salah E, Lee WH, von Delft F, Knapp S (2010) Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation. PLoS Biol 8:e1000426
-
(2010)
PLoS Biol
, vol.8
, pp. 1000426
-
-
Rellos, P.1
Pike, A.C.2
Niesen, F.H.3
Salah, E.4
Lee, W.H.5
Von Delft, F.6
Knapp, S.7
-
67
-
-
42949085382
-
A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation
-
DOI 10.1016/j.cell.2008.02.048, PII S009286740800398X
-
Erickson JR, Joiner ML, Guan X, Kutschke W, Yang J, Oddis CV, Bartlett RK, Lowe JS, O'Donnell SE, Aykin-Burns N et al (2008) A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation. Cell 133:462-474 (Pubitemid 351608692)
-
(2008)
Cell
, vol.133
, Issue.3
, pp. 462-474
-
-
Erickson, J.R.1
Joiner, M.-l.A.2
Guan, X.3
Kutschke, W.4
Yang, J.5
Oddis, C.V.6
Bartlett, R.K.7
Lowe, J.S.8
O'Donnell, S.E.9
Aykin-Burns, N.10
Zimmerman, M.C.11
Zimmerman, K.12
Ham, A.-J.L.13
Weiss, R.M.14
Spitz, D.R.15
Shea, M.A.16
Colbran, R.J.17
Mohler, P.J.18
Anderson, M.E.19
-
68
-
-
84861393490
-
Neuronal excitability and calcium/calmodulin-dependent protein kinase type II: Location, location, location
-
10.1111/j.1528-1167.2012.03474.x 1:CAS:528:DC%2BC38XhtFWhurfP 22612808
-
Liu XB, Murray KD (2012) Neuronal excitability and calcium/calmodulin- dependent protein kinase type II: location, location, location. Epilepsia 53(Suppl 1):45-52
-
(2012)
Epilepsia
, vol.53
, Issue.SUPPL. 1
, pp. 45-52
-
-
Liu, X.B.1
Murray, K.D.2
-
69
-
-
1542344969
-
Targeting of calcium/calmodulin-dependent protein kinase II
-
DOI 10.1042/BJ20031547
-
Colbran RJ (2004) Targeting of calcium/calmodulin-dependent protein kinase II. Biochem J 378:1-16 (Pubitemid 38299538)
-
(2004)
Biochemical Journal
, vol.378
, Issue.1
, pp. 1-16
-
-
Colbran, R.J.1
-
70
-
-
69049101050
-
Regulation of CaMKII in vivo: The importance of targeting and the intracellular microenvironment
-
10.1007/s11064-009-9985-9 1:CAS:528:DC%2BD1MXltlylsro%3D 19415486
-
Skelding KA, Rostas JA (2009) Regulation of CaMKII in vivo: the importance of targeting and the intracellular microenvironment. Neurochem Res 34:1792-1804
-
(2009)
Neurochem Res
, vol.34
, pp. 1792-1804
-
-
Skelding, K.A.1
Rostas, J.A.2
-
71
-
-
0028175067
-
2+/calmodulin- dependent protein kinase isoforms
-
10.1016/0167-4889(94)90221-6 1:STN:280:DyaK2c7ns1GltA%3D%3D 8130281
-
2+/calmodulin-dependent protein kinase isoforms. Biochim Biophys Acta 1221:89-101
-
(1994)
Biochim Biophys Acta
, vol.1221
, pp. 89-101
-
-
Edman, C.F.1
Schulman, H.2
-
72
-
-
0028085454
-
Alternative splicing introduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus
-
DOI 10.1083/jcb.126.4.839
-
Srinivasan M, Edman CF, Schulman H (1994) Alternative splicing introduces a nuclear localization signal that targets multifunctional CaM kinase to the nucleus. J Cell Biol 126:839-852 (Pubitemid 24252133)
-
(1994)
Journal of Cell Biology
, vol.126
, Issue.4
, pp. 839-852
-
-
Srinivasan, M.1
Edman, C.F.2
Schulman, H.3
-
73
-
-
0030609163
-
2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes
-
DOI 10.1074/jbc.272.49.31203
-
2+/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes. J Biol Chem 272:31203-31208 (Pubitemid 27527572)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.49
, pp. 31203-31208
-
-
Teresa Ramirez, M.1
Zhao, X.-L.2
Schulman, H.3
Brown, J.H.4
-
74
-
-
0038643573
-
c isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure
-
DOI 10.1161/01.RES.0000069686.31472.C5
-
Zhang T, Maier LS, Dalton ND, Miyamoto S, Ross J Jr, Bers DM, Brown JH (2003) The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circ Res 92:912-919 (Pubitemid 36542533)
-
(2003)
Circulation Research
, vol.92
, Issue.8
, pp. 912-919
-
-
Zhang, T.1
Maier, L.S.2
Dalton, N.D.3
Miyamoto, S.4
Ross Jr., J.5
Bers, D.M.6
Brown, J.H.7
-
75
-
-
0037059791
-
2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity
-
DOI 10.1074/jbc.M108525200
-
2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J Biol Chem 277:1261-1267 (Pubitemid 34968878)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.2
, pp. 1261-1267
-
-
Zhang, T.1
Johnson, E.N.2
Gu, Y.3
Morissette, M.R.4
Sah, V.P.5
Gigena, M.S.6
Belke, D.D.7
Dillmann, W.H.8
Rogers, T.B.9
Schulman, H.10
Ross Jr., J.11
Brown, J.H.12
-
76
-
-
33845284849
-
+ channels
-
DOI 10.1172/JCI26620
-
+ channels. J Clin Invest 116:3127-3138 (Pubitemid 44878627)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.12
, pp. 3127-3138
-
-
Wagner, S.1
Dybkova, N.2
Rasenack, E.C.L.3
Jacobshagen, C.4
Fabritz, L.5
Kirchhof, P.6
Maier, S.K.G.7
Zhang, T.8
Hasenfuss, G.9
Brown, J.H.10
Bers, D.M.11
Maier, L.S.12
-
78
-
-
84856087553
-
Location matters: Clarifying the concept of nuclear and cytosolic CaMKII subtypes
-
10.1161/CIRCRESAHA.111.248401 1:CAS:528:DC%2BC3MXhsF2jsrrI 21998325
-
Mishra S, Gray CB, Miyamoto S, Bers DM, Brown JH (2011) Location matters: clarifying the concept of nuclear and cytosolic CaMKII subtypes. Circ Res 109:1354-1362
-
(2011)
Circ Res
, vol.109
, pp. 1354-1362
-
-
Mishra, S.1
Gray, C.B.2
Miyamoto, S.3
Bers, D.M.4
Brown, J.H.5
-
79
-
-
36849036738
-
CaMKIIδ isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses
-
DOI 10.1074/jbc.M707083200
-
Zhang T, Kohlhaas M, Backs J, Mishra S, Phillips W, Dybkova N, Chang S, Ling H, Bers DM, Maier LS et al (2007) CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses. J Biol Chem 282:35078-35087 (Pubitemid 350232479)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.48
, pp. 35078-35087
-
-
Zhang, T.1
Kohlhaas, M.2
Backs, J.3
Mishra, S.4
Phillips, W.5
Dybkova, N.6
Chang, S.7
Ling, H.8
Bers, D.M.9
Maier, L.S.10
Olson, E.N.11
Brown, J.H.12
-
80
-
-
34249857023
-
δC is a common intermediate of diverse death stimuli-induced heart muscle cell apoptosis
-
DOI 10.1074/jbc.M611507200
-
Zhu W, Woo AY, Yang D, Cheng H, Crow MT, Xiao RP (2007) Activation of CaMKIIdeltaC is a common intermediate of diverse death stimuli-induced heart muscle cell apoptosis. J Biol Chem 282:10833-10839 (Pubitemid 47093465)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.14
, pp. 10833-10839
-
-
Zhu, W.1
Woo, A.Y.-H.2
Yang, D.3
Cheng, H.4
Crow, M.T.5
Xiao, R.-P.6
-
81
-
-
74049097964
-
Cardioprotection by CaMKII-deltaB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70
-
10.1161/CIRCRESAHA.109.210914 1:CAS:528:DC%2BD1MXhs1aqt7bL 19910575
-
Peng W, Zhang Y, Zheng M, Cheng H, Zhu W, Cao CM, Xiao RP (2010) Cardioprotection by CaMKII-deltaB is mediated by phosphorylation of heat shock factor 1 and subsequent expression of inducible heat shock protein 70. Circ Res 106:102-110
-
(2010)
Circ Res
, vol.106
, pp. 102-110
-
-
Peng, W.1
Zhang, Y.2
Zheng, M.3
Cheng, H.4
Zhu, W.5
Cao, C.M.6
Xiao, R.P.7
-
82
-
-
69949120824
-
Critical role of nuclear calcium/calmodulin-dependent protein kinase II deltaB in cardiomyocyte survival in cardiomyopathy
-
10.1074/jbc.M109.003186 1:CAS:528:DC%2BD1MXhtV2nsLnN 19602725
-
Little GH, Saw A, Bai Y, Dow J, Marjoram P, Simkhovich B, Leeka J, Kedes L, Kloner RA, Poizat C (2009) Critical role of nuclear calcium/calmodulin- dependent protein kinase II deltaB in cardiomyocyte survival in cardiomyopathy. J Biol Chem 284:24857-24868
-
(2009)
J Biol Chem
, vol.284
, pp. 24857-24868
-
-
Little, G.H.1
Saw, A.2
Bai, Y.3
Dow, J.4
Marjoram, P.5
Simkhovich, B.6
Leeka, J.7
Kedes, L.8
Kloner, R.A.9
Poizat, C.10
-
83
-
-
78751647632
-
Cardiac hypertrophy and heart failure development through Gq and CaM kinase II signaling
-
10.1097/FJC.0b013e3181e1d263 1:CAS:528:DC%2BC3MXjs1Wnug%3D%3D 20531218
-
Mishra S, Ling H, Grimm M, Zhang T, Bers DM, Brown JH (2010) Cardiac hypertrophy and heart failure development through Gq and CaM kinase II signaling. J Cardiovasc Pharmacol 56:598-603
-
(2010)
J Cardiovasc Pharmacol
, vol.56
, pp. 598-603
-
-
Mishra, S.1
Ling, H.2
Grimm, M.3
Zhang, T.4
Bers, D.M.5
Brown, J.H.6
-
84
-
-
0028918056
-
Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle
-
10.1074/jbc.270.5.2074 1:CAS:528:DyaK2MXjsV2ks7c%3D 7836435
-
Hain J, Onoue H, Mayrleitner M, Fleischer S, Schindler H (1995) Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle. J Biol Chem 270:2074-2081
-
(1995)
J Biol Chem
, vol.270
, pp. 2074-2081
-
-
Hain, J.1
Onoue, H.2
Mayrleitner, M.3
Fleischer, S.4
Schindler, H.5
-
85
-
-
18144391476
-
Cardiac type 2 inositol 1,4,5-trisphosphate receptor: Interaction and modulation by calcium/calmodulin-dependent protein kinase II
-
DOI 10.1074/jbc.M414212200
-
Bare DJ, Kettlun CS, Liang M, Bers DM, Mignery GA (2005) Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II. J Biol Chem 280:15912-15920 (Pubitemid 40616714)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.16
, pp. 15912-15920
-
-
Bare, D.J.1
Kettlun, C.S.2
Liang, M.3
Bers, D.M.4
Mignery, G.A.5
-
86
-
-
84868629814
-
CaMKII determines mitochondrial stress responses in heart
-
10.1038/nature11444 1:CAS:528:DC%2BC38XhsVykt7bI 23051746
-
Joiner ML, Koval OM, Li J, He BJ, Allamargot C, Gao Z, Luczak ED, Hall DD, Fink BD, Chen B et al (2012) CaMKII determines mitochondrial stress responses in heart. Nature 491:269-273
-
(2012)
Nature
, vol.491
, pp. 269-273
-
-
Joiner, M.L.1
Koval, O.M.2
Li, J.3
He, B.J.4
Allamargot, C.5
Gao, Z.6
Luczak, E.D.7
Hall, D.D.8
Fink, B.D.9
Chen, B.10
-
87
-
-
76349084460
-
2+ handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice
-
10.1161/CIRCRESAHA.109.207423 1:CAS:528:DC%2BC3cXhsVyht7Y%3D 19959778
-
2+ handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice. Circ Res 106:354-362
-
(2010)
Circ Res
, vol.106
, pp. 354-362
-
-
Zhang, T.1
Guo, T.2
Mishra, S.3
Dalton, N.D.4
Kranias, E.G.5
Peterson, K.L.6
Bers, D.M.7
Brown, J.H.8
-
88
-
-
80355130016
-
A-kinase anchoring proteins: Scaffolding proteins in the heart
-
10.1152/ajpheart.00569.2011 1:CAS:528:DC%2BC3MXhsFaktrzE 21856912
-
Diviani D, Dodge-Kafka KL, Li J, Kapiloff MS (2011) A-kinase anchoring proteins: scaffolding proteins in the heart. Am J Physiol Heart Circ Physiol 301:H1742-1753
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
, pp. 1742-1753
-
-
Diviani, D.1
Dodge-Kafka, K.L.2
Li, J.3
Kapiloff, M.S.4
-
89
-
-
70350496562
-
2+/calmodulin-dependent protein kinase II and modulate phospholamban phosphorylation
-
10.1074/jbc.M109.044990 1:CAS:528:DC%2BD1MXht1SqsbrI 19671701
-
2+/calmodulin- dependent protein kinase II and modulate phospholamban phosphorylation. J Biol Chem 284:28212-28221
-
(2009)
J Biol Chem
, vol.284
, pp. 28212-28221
-
-
Singh, P.1
Salih, M.2
Tuana, B.S.3
-
90
-
-
84860842301
-
Substrate-selective and calcium-independent activation of CaMKII by alpha-actinin
-
10.1074/jbc.M112.351817 1:CAS:528:DC%2BC38XmsVehur4%3D 22427672
-
Jalan-Sakrikar N, Bartlett RK, Baucum AJ 2nd, Colbran RJ (2012) Substrate-selective and calcium-independent activation of CaMKII by alpha-actinin. J Biol Chem 287:15275-15283
-
(2012)
J Biol Chem
, vol.287
, pp. 15275-15283
-
-
Jalan-Sakrikar, N.1
Bartlett, R.K.2
Baucum II, A.J.3
Colbran, R.J.4
-
91
-
-
16244382837
-
2+/calmodulin-dependent protein kinase II activity in living neurons
-
DOI 10.1523/JNEUROSCI.0085-05.2005
-
2+ /calmodulin-dependent protein kinase II activity in living neurons. J Neurosci 25:3107-3112 (Pubitemid 40463545)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.12
, pp. 3107-3112
-
-
Takao, K.1
Okamoto, K.-I.2
Nakagawa, T.3
Neve, R.L.4
Nagai, T.5
Miyawaki, A.6
Hashikawa, T.7
Kobayashi, S.8
Hayashi, Y.9
-
92
-
-
80052962709
-
Fluorescence resonance energy transfer-based sensor Camui provides new insight into mechanisms of calcium/calmodulin-dependent protein kinase II activation in intact cardiomyocytes
-
10.1161/CIRCRESAHA.111.247148 1:CAS:528:DC%2BC3MXhtFyjt7bN 21835909
-
Erickson JR, Patel R, Ferguson A, Bossuyt J, Bers DM (2011) Fluorescence resonance energy transfer-based sensor Camui provides new insight into mechanisms of calcium/calmodulin-dependent protein kinase II activation in intact cardiomyocytes. Circ Res 109:729-738
-
(2011)
Circ Res
, vol.109
, pp. 729-738
-
-
Erickson, J.R.1
Patel, R.2
Ferguson, A.3
Bossuyt, J.4
Bers, D.M.5
-
93
-
-
40949113123
-
Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity
-
10.1016/j.bbrc.2008.02.070 1:CAS:528:DC%2BD1cXjs12gtbY%3D 18302935
-
Kwok S, Lee C, Sanchez SA, Hazlett TL, Gratton E, Hayashi Y (2008) Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity. Biochem Biophys Res Commun 369:519-525
-
(2008)
Biochem Biophys Res Commun
, vol.369
, pp. 519-525
-
-
Kwok, S.1
Lee, C.2
Sanchez, S.A.3
Hazlett, T.L.4
Gratton, E.5
Hayashi, Y.6
-
94
-
-
84867084476
-
Improving FRET dynamic range with bright green and red fluorescent proteins
-
10.1038/nmeth.2171 1:CAS:528:DC%2BC38Xhtlajs7zI 22961245
-
Lam AJ, St-Pierre F, Gong Y, Marshall JD, Cranfill PJ, Baird MA, McKeown MR, Wiedenmann J, Davidson MW, Schnitzer MJ et al (2012) Improving FRET dynamic range with bright green and red fluorescent proteins. Nat Methods 9:1005-1012
-
(2012)
Nat Methods
, vol.9
, pp. 1005-1012
-
-
Lam, A.J.1
St-Pierre, F.2
Gong, Y.3
Marshall, J.D.4
Cranfill, P.J.5
Baird, M.A.6
McKeown, M.R.7
Wiedenmann, J.8
Davidson, M.W.9
Schnitzer, M.J.10
-
95
-
-
35348887075
-
FRET-based biosensors for protein kinases: Illuminating the kinome
-
DOI 10.1039/b706628g
-
Zhang J, Allen MD (2007) FRET-based biosensors for protein kinases: illuminating the kinome. Mol Biosyst 3:759-765 (Pubitemid 47587185)
-
(2007)
Molecular BioSystems
, vol.3
, Issue.11
, pp. 759-765
-
-
Zhang, J.1
Allen, M.D.2
|