Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations

Science

Volumn 279, Issue 5348, 1998, Pages 227-230

  De Koninck, Paul ^a   Schulman, Howard ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; ENZYME ACTIVATION; ENZYME SPECIFICITY; NERVE CELL PLASTICITY; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; BASE SEQUENCE; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALMODULIN; CERCOPITHECUS AETHIOPS; COS CELLS; ENZYME ACTIVATION; ENZYMES, IMMOBILIZED; MOLECULAR SEQUENCE DATA; NEURONAL PLASTICITY; PHOSPHORYLATION; PHOSPHOTHREONINE; POLYVINYL CHLORIDE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0032498172     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.279.5348.227     Document Type: Article

References (47)

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47. We thank D. Profitt and R. Schneeveis for building the pulse-flow device; S. Sather for help with site-directed mutagenesis and early studies on immobilized kinase; A. Braun, P. Hanson, T. Meyer, A. Naini, and R. Y. Tsien for helpful discussions; and J. Ferrell and L. Stryer for their comments on the manuscript. Supported by NIH grants GM40600 and GM30179 and by a Human Frontier Science Program Organization fellowship to P.D.K.