Intracellular translocation of calmodulin and Ca2+/calmodulin-dependent protein kinase II during the development of hypertrophy in neonatal cardiomyocytes

Biochemical and Biophysical Research Communications

Volumn 396, Issue 2, 2010, Pages 515-521

  Gangopadhyay, Jaya Pal ^a   Ikemoto, Noriaki ^a,b  

^a BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Calmodulin; CaMKII; Cardiomyocytes; Hypertrophy; Protein translocation; Ryanodine receptor

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; CALMODULIN; DANTROLENE; ENDOTHELIN 1; RYANODINE RECEPTOR 2;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CALCIUM SIGNALING; CELL NUCLEUS; CELL SURFACE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; FLUORESCENCE ANALYSIS; HEART HYPERTROPHY; IMMUNOHISTOCHEMISTRY; MOLECULAR INTERACTION; NEWBORN; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CALMODULIN; CARDIOMEGALY; CELL NUCLEUS; CELLS, CULTURED; CYTOPLASM; ENDOTHELIN-1; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 77952743060     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.04.129     Document Type: Article

References (32)

1. Simpson P. Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an alpha 1 adrenergic response. J. Clin. Invest. 72 2 (1983) 732-738
2. Shubeita H.E., McDonough P.M., Harris A.N., Knowlton K.U., Glembotski C.C., Brown J.H., and Chien K.R. Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy. J. Biol. Chem. 265 33 (1990) 20555-20562
3. Hamada T., Gangopadhyay J.P., Mandl A., Erhardt P., and Ikemoto N. Defective regulation of the ryanodine receptor induces hypertrophy in cardiomyocytes. Biochem. Biophys. Res. Commun. 380 3 (2009) 493-497
4. Kobayashi S., Yano M., Suetomi T., Ono M., Tateishi H., Mochizuki M., Xu X., Uchinoumi H., Okuda S., Yamamoto T., Koseki N., Kyushiki H., Ikemoto N., and Matsuzaki M. Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor. J. Am. Coll. Cardiol. 53 21 (2009) 1993-2005
5. Paul-Pletzer K., Yamamoto T., Bhat M.B., Ma J., Ikemoto N., Limenez L.S., Morimoto H., Williams P.G., and Parness J. Identification of a dantrolene-binding sequence on the skeletal muscle ryanodine receptor. J. Biol. Chem. 277 (2002) 34918-34923
6. Kobayashi S., Bannister M.L., Gangopadhyay J.P., Hamada T., Parness J., and Ikemoto N. Dantrolene stabilizes domain interactions within the Ryanodine receptor. J. Biol. Chem. 280 (2005) 6580-6587
7. Oda T., Yano M., Yamamoto T., Tokuhisa T., Okuda S., Doi M., Ohkusa T., Ikeda Y., Kobayashi S., Ikemoto N., and Matsuzaki M. Defective regulation of interdomain interactions within the ryanodine receptor plays a key role in the pathogenesis of heart failure. Circulation 111 25 (2005) 3400-3410
8. Yamamoto T., Yano M., Xu X., Uchinoumi H., Tateishi H., Mochizuki M., Oda T., Kobayashi S., Ikemoto N., and Matsuzaki M. Identification of target domains of the cardiac ryanodine receptor to correct channel disorder in failing hearts. Circulation 12 117 (2008) 762-772
9. 2+ leak in failing hearts. Cardiovasc. Res. 81 3 (2009) 536-545
10. 2+ and calmodulin. Biochemistry 39 (2000) 7807-7812
11. 2+, adenine nucleotide, and calmodulin. J. Biol. Chem. 262 (1987) 3065-3073
12. 2+ sensitivity of skeletal and cardiac muscle ryanodine receptors in the presence of calmodulin. Am. J. Physiol. 279 (2000) C724-C733
13. 2+ release channel. J. Clin. Invest. 117 5 (2007) 1344-1353
14. 2+-calmodulin-dependent protein kinase II, J. Mol. Cell. Cardiol., 2010 (Epub ahead of print).
15. 2+ levels in right atrial myocardium of patients with atrial fibrillation. Circ. Res. 106 (2010) 1134-1144
16. Sag C.M., Wadsack D.P., Khabbazzadeh S., Abesser M., Grefe C., Neumann K., Opiela M.K., Backs J., Olson E.N., Brown J.H., Neef S., Maier S.K., and Maier L.S. Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure. Circ. Heart Fail. 2 (2009) 664-675
17. 2+ leak promotes atrial fibrillation in mice. J. Clin. Invest. 119 (2009) 1940-1951
18. Zhang W. Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy. Cardiovasc. Res. 53 (2002) 294-303
19. 2+/calmodulin-dependent protein kinase II delta and protein kinase D overexpression reinforce the histon deacetylase 5 redistribution in heart failure. Circ. Res. 102 (2008) 695-702
20. 2+/calmodulin-dependent kinase II and calcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy. J. Biol. Chem. 275 (2000) 15239-15245
21. Heineke J., and Molkentin J. Regulation of cardiac hypertrophy by intracellular signaling pathways. Nat. Rev. 7 (2006) 589-600
22. Toth A., Nickson P., Quin L.L., and Erhardt P. Differential regulation of cardiomyocyte survival and hypertrophy by MDM2, and E3 ubiquitin ligase. J. Biol. Chem. 281 (2006) 3679-3689
23. 2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium. Circ. Res. 84 (1999) 713-721
24. Maier L.S. Role of CaMKII for signaling and regulation in the heart. Front. Biosci. 14 (2009) 486-496
25. 2+/calmodulin-dependent protein kinase (CaMK) in excitation-contraction coupling in the heart. Cardiovasc. Res. 73 (2007) 631-640
26. Grueter C.E., Colbran R.J., and Anderson M.E. CaMKII, an emerging molecular driver for calcium homeostasis, arrhythmias, and cardiac dysfunction. J. Mol. Med. 85 (2007) 5-14
27. Yamamoto T., and Ikemoto N. Peptide probe study of the critical regulatory domain of the cardiac ryanodine receptor. Biochem. Biophys. Res. Comm. 291 (2002) 1102-1108
28. 2+/calmodulin-dependent protein kinase II. Biochem. J. 364 Pt. 3 (2002) 593-611
29. 2+ oscillations. Science 279 5348 (1998) 227-230
30. Meyer T., Hanson P.I., Stryer L., and Schulman H. Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science 256 (1992) 1199-1202
31. Singla S.I., Hudmon A., Goldberg J.M., Smith J.L., and Schulman H. Molecular characterization of calmodulin trapping by calcium/calmodulin-dependent protein kinase II. J. Biol. Chem. 276 (2001) 29353-29360
32. 2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J. Clin. Invest. 119 (2009) 1230-1240