Cardiac calmodulin kinase: A potential target for drug design

Current Medicinal Chemistry

Volumn 18, Issue 24, 2011, Pages 3707-3713

  Banyasz T ^a   Szentandrassy N ^a   Toth A ^b   Nanasi P P ^a   Magyar, J ^a   Chen Izu, Y ^c,d,e  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF SZEGED   (Hungary)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d Davis   (United States)

^e Tupper Hall   (United States)

Author keywords

Arrhythmia; Calmodulin kinase; Heart; Hypertrophy; Ion channels

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; AUTO CAMTIDE 2 RELATED INHIBITORY PEPTIDE; AUTOCAMTIDE 3 CONTROL; AUTOCAMTIDE 3 INHIBITOR; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II INHIBITOR; CALCIUM CHANNEL L TYPE; CASPASE 3; CHLORIDE CHANNEL; CK 281 302; CK 291 317; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; HISTONE DEACETYLASE; ION CHANNEL; KN 92; MYOCYTE ENHANCER FACTOR 2; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; POTASSIUM CHANNEL; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARRHYTHMOGENESIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CYTOSOL; DEFIBRILLATOR; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME STRUCTURE; EXTRACELLULAR CALCIUM; GENE INDUCTION; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HEART DILATATION; HEART DISEASE; HEART EJECTION FRACTION; HEART FAILURE; HEART FUNCTION; HEART HYPERTROPHY; HEART MITOCHONDRION; HEART MUSCLE CONTRACTILITY; HEART MUSCLE POTENTIAL; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE HYPERTROPHY; HUMAN; MOLECULAR BIOLOGY; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN TARGETING; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SARCOPLASMIC RETICULUM; SIGNAL TRANSDUCTION; SODIUM CURRENT; TRANSCRIPTION REGULATION;

ARRHYTHMIAS, CARDIAC; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CHLORIDE CHANNELS; DRUG DESIGN; ENZYME ACTIVATION; HUMANS; POTASSIUM CHANNELS; PROTEIN KINASE INHIBITORS; SODIUM CHANNELS;

EID: 80051981571     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986711796642409     Document Type: Article

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