Critical determinants of Ca2+-dependent inactivation within an EF-hand motif of L-type Ca2+ channels

Biophysical Journal

Volumn 78, Issue 4, 2000, Pages 1906-1920

  Peterson, Blaise Z ^a   Lee, Joanna S ^a   Mulle, Jennifer G ^a   Wang, Van ^a   De Leon, Marita ^a   Yue, David T ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL; CALMODULIN;

AMINO ACID SUBSTITUTION; ARTICLE; CALCIUM BINDING; CALCIUM CELL LEVEL; CARBOXY TERMINAL SEQUENCE; DNA FLANKING REGION; GENETIC TRANSDUCTION; MUTATION; NEGATIVE FEEDBACK;

EID: 0034031414     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(00)76739-7     Document Type: Article

References (54)

1. Adams, B., and T. Tanabe. 1997. Structural regions of the cardiac Ca channel alpha subunit involved in Ca-dependent inactivation, J. Gen. Physiol. 110:379-389.
2. Ames, J. B., R. Ishima, T. Tanaka, J. I. Gordon, L. Stryer, and M. Ikura. 1997. Molecular mechanics of calcium-myristoyl switches. Nature. 389: 198-202.
3. Babitch, J. 1990. Channel hands. Nature. 346:321-322.
4. Bernatchez, G., D. Talwar, and L. Parent. 1998. Mutations in the EF-hand motif impair the inactivation of barium currents of the cardiac alpha1C channel. Biophys. J. 75:1727-1739.
5. Brehm, P., and R. Eckert. 1978. Calcium entry leads to inactivation of calcium channel in Paramecium. Science. 202:1203-1206.
6. Chazin, W. J. 1995. Releasing the calcium trigger. Nat. Struct Biol. 2:707-710.
7. Deisseroth, K., H. Bito, and R. W. Tsien. 1996. Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity. Neuron. 16:89-101.
8. 2+ channels. Science. 270: 1502-1506.
9. De Waard, M., C. A. Gurnett, and K. P. Campbell. 1996. Structural and functional diversity of voltage-activated calcium channels. In Ion Channels. T. Narahashi, editor. Plenum Press, New York. 41-87.
10. Falke, J. J., S. K. Drake, A. L. Hazard, and O. B. Peersen. 1994. Molecular tuning of ion binding to calcium signaling proteins. Q. Rev. Biophys. 27:219-290.
11. Ferreira, G., J. Yi, E. Rios, and R. Shirokov. 1997. Ion-dependent inactivation of barium current through L-type calcium channels. J. Gen. Physiol. 109:449-461.
12. Flaherty, K. M., S. Zozulya, L. Stryer, and D. B. McKay. 1993. Three-dimensional structure of recoverin, a calcium sensor in vision. Cell. 75:709-716.
13. 2+-induced conformational transition of troponin C. A trigger for muscle contraction. J. Biol. Chem. 261:2638-2644.
14. Ho, S., H. Hunt, R. Horton, J. Pullen, and L. Pease. 1989. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene. 77:51-59.
15. 2+ channels. Neuron. 9:197-207.
16. 2+ channels. Neuron. 12:1301-1318.
17. le calcium channels. J. Gen. Physiol. 112:125-143.
18. Kass, R. S., and M. Sanguinetti. 1984. Inaclivation of calcium channel current in the calf cardiac Purkinje fiber. Evidence for voltage-and calcium-mediated mechanisms. J. Gen. Physiol. 84:705-726.
19. Klockner, U., G. Mikala, M. Varadi, G. Varadi, and A. Schwartz. 1995. Involvement of the carboxyl-terminal region of the alpha 1 subunit in voltage-dependent inactivation of cardiac calcium channels. J. Biol. Chem. 270:17306-17310.
20. + channel S4. Neuron. 16:387-397.
21. Lee, K., E. Marban, and R. W. Tsien. 1985. Inactivation of calcium channels in mammalian heart cells: joint dependence on membrane potential and intracellular calcium. J. Physiol. 364:395-411.
22. 2+/calmodulin binds to and modulates P/Q-type calcium channels. Nature. 399:155-159.
23. Linse, S., and S. Forsen. 1995. Determinants that govern high-affinity calcium binding. Adv. Second Messenger Phosphoprotein Res. 30: 89-151.
24. Linz, K. W., and R. Meyer. 1998. Control of L-type calcium current during the action potential of guinea-pig ventricular myocytes. J. Physiol. 513:425-442.
25. + channel. Neuron. 19:175-184.
26. 2+ channels. J. Gen. Physiol. 111:463-475.
27. O'Rourke, B., D. A. Kass, G. F. Tomaselli, S. Kaab, R. Tunin, and E. Marban. 1999. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure: I. Experimental study. Circ. Res. 84:562-570.
28. Patil, P. G., D. L. Brody, and D. T. Yue. 1998. Preferential closed-state inactivation of neuronal calcium channels. Neuron. 20:1027-1038.
29. Perez-Reyes, E., A. Castellano, H. S. Kim, P. Bertrand, E. Baggstrom, A. E. Lacerda, X. Y. Wei, and L. Birnbaumer. 1992. Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel. J. Biol. Chem. 267:1792-1797.
30. Perez-Reyes, E., and T. Schneider. 1994. Calcium channels: structure, function, and classification. Drug Dev. Res. 33:295-318.
31. +-channel activation gating. Science. 285:73-78.
32. 2+-dependent inactivation of L-type calcium channels. Neuron. 22:549-558.
33. 2+ channel depends on calmodulin. Proc. Natl. Acad. Sci. USA. 96:2435-2438.
34. Rhoads, A. R., and F. Friedberg. 1997. Sequence motifs for calmodulin recognition. FASEB J. 11:331-340.
35. 2+ channels at low channel density. Biophys. J. 58: 985-995.
36. 2+-dependent inactivation of cardiac L-type Ca2+ channels does not affect their voltage sensor. J. Gen. Physiol. 102:1005-1030.
37. Simon, S., and R. Llinas. 1985. Compartmentalizalion of the submembrane calcium activity during calcium influx and its significance in transmitter release. Biophys J. 48:485-498.
38. 2+-channel alpha 2/delta subunit in Xenopus oocytes. Biochim. Biophys. Acta. 1137:39-44.
39. 2+ channel inactivation. Segment exchange analysis of the carboxyl-terminal cytoplasmic motif encoded by exons 40-42 of the human alpha1C subunit gene. J. Biol. Chem. 273:957-963.
40. 2+ dependence of inactivation. J. Biol. Chem. 272: 3560-3566.
41. Soong, T. W., A. Stea, C. D. Hodson, S. J. Dubel, S. R. Vincent, and T. P. Snutch. 1993. Structure and functional expression of a member of the low voltage-activated calcium channel family. Science. 260:1133-1136.
42. Standen, N., and P. Stanfield. 1982. A binding-site model for calcium channel inactivation that depends on calcium entry. Proc. R. Soc. (Lond). 217:101-110.
43. Tanaka, T., J. B. Ames, T. S. Harvey, L. Stryer, and M. Ikura. 1995. Sequestration of the membrane-targeting myristoyl group of recoverin in the calcium-free state. Nature. 376:444-447.
44. Tomlinson, W. J., A. Stea, E. Bourinet, P. Charnet, J. Nargeot, and T. P. Snutch. 1993. Functional properties of a neuronal class C L-type calcium channel. Neuropharmacology. 32:1117-1126.
45. 2+ channels. Biophys. J. 76:101α. (Abstr.).
46. 2+ channels: role in channel function. Trends. Neurosci. 21:148-154.
47. 2+ channels. J. Biol. Chem. 266:21943-21947.
48. Winslow, R., J. Rice, S. Jafri, E. Marban, and B. O'Rourke. 1999. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure: II. Model study. Circ. Res. 84:571-586.
49. Yang, N., and R. Horn. 1996. Molecular basis of charge movement in voltage-gated sodium channels. Neuron. 16:113-122.
50. Zhang, J. F., P. T. Ellinor, R. W. Aldrich, and R. W. Tsien. 1994. Molecular determinants of voltage-dependent inactivation in calcium channels. Nature. 372:97-100.
51. 2+-binding domains. Proc. Natl. Acad. Sci. USA. 94:2301-2305.
52. Zozulya, S., and L. Stryer. 1992. Calcium-myristoyl protein switch. Proc. Natl. Acad. Sci. USA. 89:11569-11573.
53. Zuhlke, R. D., G. S. Pitt, K. Deisseroth, R. W. Tsien, and H. Reuter. 1999. Calmodulin supports both inactivation and facilitation of L-type calcium channels. Nature. 399:159-162.
54. lc subunit. Proc. Natl. Acad. Sci. USA. 95:3287-3294.