Accurate prediction of the bound form of the akt pleckstrin homology domain using normal mode analysis to explore structural flexibility

Journal of Chemical Information and Modeling

Volumn 51, Issue 9, 2011, Pages 2352-2360

  Tran, Hoang T ^a   Zhang, Shuxing ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIGANDS; MOLECULAR MODELING;

ACCURATE PREDICTION; DOCKING METHODS; DOMAIN COMPLEXES; MOLECULAR DOCKING; NORMAL MODE ANALYSIS; PLECKSTRIN HOMOLOGY DOMAINS; STRUCTURAL FLEXIBILITIES; X RAY CRYSTAL STRUCTURES;

CRYSTAL STRUCTURE;

PHOSPHOPROTEIN; PLASMA PROTEIN; PLATELET PROTEIN P47; PROTEIN KINASE B;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

BLOOD PROTEINS; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; PHOSPHOPROTEINS; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 80053318639     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci2001742     Document Type: Article

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