Duodenal-jejunal bypass improves glucose metabolism and adipokine expression independently of weight loss in a diabetic rat model

Obesity Surgery

Volumn 23, Issue 9, 2013, Pages 1436-1444

  Hu, Chunxiao ^a   Zhang, Guangyong ^a   Sun, Dong ^a   Han, Haifeng ^a   Hu, Sanyuan ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Adipokine; Duodenal jejunal bypass; High fat diet; Streptozotocin; Type 2 diabetes mellitus

Indexed keywords

ADIPOCYTOKINE; FATTY ACID; GLUCOSE; INTERLEUKIN 6; LEPTIN; MESSENGER RNA; STREPTOZOCIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; DUODENUM; DUODENUM JEJUNUM BYPASS; ENZYME ACTIVITY; FATTY ACID BLOOD LEVEL; FOOD INTAKE; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLYCEMIC CONTROL; INSULIN SENSITIVITY; INTESTINE BYPASS; JEJUNUM; MALE; MORBID OBESITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT REDUCTION;

ADIPONECTIN; ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DUODENUM; EATING; GASTRIC BYPASS; GENE EXPRESSION REGULATION; GLUCOSE; HOMEOSTASIS; INSULIN RESISTANCE; INTERLEUKIN-6; JEJUNUM; MALE; RATS; RATS, SPRAGUE-DAWLEY; TUMOR NECROSIS FACTOR-ALPHA; WEIGHT LOSS;

EID: 84881182577     PISSN: 09608923     EISSN: 17080428     Source Type: Journal    
DOI: 10.1007/s11695-013-0976-1     Document Type: Article

References (50)

1. Zimmet P, Alberti KG, Shaw J. Global and societal implications of the diabetes epidemic. Nature. 2001;414(7):782. Epub 2001 Dec 13. PMID: 11742409. (Pubitemid 34000780)
2. Kopelman PG. Obesity as a medical problem. Nature. 2000;404(6778):635-43. Epub 2000 Apr 6. PMID: 10766250. (Pubitemid 30205068)
3. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet. 2005;365(9468):1415-28. Epub 2005 Apr 20. PMID: 15836891. (Pubitemid 40523737)
4. Scherer PE. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes. 2006;55(6):1537-45. Epub 2006 May 29. PMID: 16731815. (Pubitemid 44324105)
5. Antuna-Puente B, Feve B, Fellahi S, et al. Obesity, inflammation and insulin resistance: which role for adipokines. Therapie. 2007;62(4):285-92. Epub 2007 Nov 6. PMID: 17983554. (Pubitemid 351211744)
6. Wellen KE, Hotamisligil GS. Inflammation, stress, and diabetes. J Clin Invest. 2005;115(5):1111-9. Epub 2005 May 03. PMID: 15864338. (Pubitemid 40629025)
7. Shoelson SE, Lee J, Goldfine AB. Inflammation and insulin resistance. J Clin Invest. 2006;116(7):1793-801. Epub 2006 Jul 11. PMID: 16823477.
8. Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature. 2006;444(7121):840-6. Epub 2006 Dec 14. PMID: 17167471. (Pubitemid 46024990)
9. Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science. 1993;259(5091):87-91. Epub 1993 Jan 1. PMID: 7678183. (Pubitemid 23036092)
10. Fasshauer M, Klein J, Neumann S, et al. Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes. FEBS Lett. 2001;507(2):142-6. Epub 2001 Oct 26. PMID: 11684087. (Pubitemid 33001531)
11. Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292(14):1724-37. Epub 2004 Oct 13. PMID: 15479938. (Pubitemid 39346675)
12. Pories WJ, Swanson MS, MacDonald KG, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg. 1995;222(3):339-50. discussion 50-2. Epub 1995 Oct 13. PMID: 7677463.
13. Habib P, Scrocco JD, Terek M, et al. Effects of bariatric surgery on inflammatory, functional and structural markers of coronary atherosclerosis. Am J Cardiol. 2009;104(9):1251-5. Epub 2009 Nov 1. PMID: 19840571.
14. Moschen AR, Molnar C, Geiger S, et al. Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor alpha expression. Gut. 2010;59(9):1259-64. Epub 2010 Sep 01. PMID: 20660075.
15. Garcia de la Torre N, Rubio MA, Bordiu E, et al. Effects of weight loss after bariatric surgery for morbid obesity on vascular endothelial growth factor-A, adipocytokines, and insulin. J Clin Endocrinol Metab. 2008;93(11):4276-81. Epub 2008 Aug 21. PMID: 18713823. (Pubitemid 352789522)
16. Cancello R, Henegar C, Viguerie N, et al. Reduction of macrophage infiltration and chemoattractant gene expression changes in white adipose tissue of morbidly obese subjects after surgery-induced weight loss. Diabetes. 2005;54(8):2277-86. Epub 2005 Jul 28. PMID: 16046292. (Pubitemid 41134253)
17. Miller GD, Nicklas BJ, Fernandez A. Serial changes in inflammatory biomarkers after Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis. 2011;7(5):618-24. Epub 2011 May 07. PMID: 21546319.
18. Speck M, Cho YM, Asadi A, et al. Duodenal-jejunal bypass protects GK rats from {beta}-cell loss and aggravation of hyperglycemia and increases enteroendocrine cells coexpressing GIP and GLP-1. Am J Physiol Endocrinol Metab. 2011;300(5):E923-32. Epub 2011 Feb 10. PMID: 21304061.
19. Araujo AC, Bonfleur ML, Balbo SL, et al. Duodenal-jejunal bypass surgery enhances glucose tolerance and beta-cell function in Western diet obese rats. Obes Surg. 2012;22(5):819-26. Epub 2012 Mar 14. PMID: 22411572.
20. Rubino F, Marescaux J. Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease. Ann Surg. 2004;239(1):1-11. Epub 2003 Dec 20. PMID: 14685093. (Pubitemid 38176365)
21. Wang TT, Hu SY, Gao HD, et al. Ileal transposition controls diabetes as well as modified duodenal jejunal bypass with better lipid lowering in a nonobese rat model of type II diabetes by increasing GLP-1. Ann Surg. 2008;247(6):968-75. Epub 2008 Jun 04. PMID: 18520224. (Pubitemid 351770417)
22. Geloneze B, Geloneze SR, Chaim E, et al. Metabolic surgery for non-obese type 2 diabetes incretins, adipocytokines, and insulin secretion/resistance changes in a 1-year interventional clinical controlled study. Ann Surg. 2012;256(1):72-8. Epub 2012 Jul. PMID: 22664560.
23. Liu SZ, Sun D, Zhang GY, et al. A high-fat diet reverses improvement in glucose tolerance induced by duodenal-jejunal bypass in type 2 diabetic rats. Chin Med J (Engl). 2012;125(5):912-9. Epub 2012 Apr 12. PMID: 22490596.
24. Pacheco D, de Luis DA, Romero A, et al. The effects of duodenal-jejunal exclusion on hormonal regulation of glucose metabolism in Goto-Kakizaki rats. Am J Surg. 2007;194(2):221-4. Epub 2007 Jul 10. PMID: 17618808. (Pubitemid 47008973)
25. Rubino F, Zizzari P, Tomasetto C, et al. The role of the small bowel in the regulation of circulating ghrelin levels and food intake in the obese Zucker rat. Endocrinology. 2005;146(4):1745-51. Epub 2004 Dec 31. PMID: 15625244. (Pubitemid 40396883)
26. Fried M, Ribaric G, Buchwald JN, et al. Metabolic surgery for the treatment of type 2 diabetes in patients with BMI < 35 kg/m(2): an integrative review of early studies. Obes Surg. 2010;20(6):776-90. Epub 2010 May 21. PMID: 20333558.
27. Geloneze B, Geloneze SR, Fiori C, et al. Surgery for nonobese type 2 diabetic patients: an interventional study with duodenal-jejunal exclusion. Obes Surg. 2009;19(8):1077-83. Epub 2009 Jul 17. PMID: 15475464.
28. Reis CEG, Alvarez-Leite JI, Bressan J, et al. Role of bariatric-metabolic surgery in the treatment of obese type 2 diabetes with body mass index < 35 kg/m(2): a literature review. Diabetes Technol The. 2012;14(4):365-72. Epub 2012 Apr 02. PMID: 22126155.
29. Swarbrick MM, Stanhope KL, Austrheim-Smith IT, et al. Longitudinal changes in pancreatic and adipocyte hormones following Roux-en-Y gastric bypass surgery. Diabetologia. 2008;51(10):1901-11. Epub 2008 Aug 16. PMID: 18704364.
30. Cummings BP, Strader AD, Stanhope KL, et al. Ileal interposition surgery improves glucose and lipid metabolism and delays diabetes onset in the UCD-T2DM rat. Gastroenterology. 2010;138(7):2437-46. 46 e1. Epub 2010 Mar 17. PMID: 20226188.
31. Evans JL, Goldfine ID, Maddux BA, et al. Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev. 2002;23(5):599-622. Epub 2002 Oct 10. PMID: 12372842. (Pubitemid 35191625)
32. Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes. 1997;46(1):3-10. Epub 1997 Jan 01. PMID: 8971073. (Pubitemid 27009941)
33. Rubino F, Forgione A, Cummings DE, et al. The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes. Ann Surg. 2006;244(5):741-9. Epub 2006 Oct 25. PMID: 17060767. (Pubitemid 44629948)
34. Lee YS, Shin S, Shigihara T, et al. Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis. Diabetes. 2007;56(6):1671-9. Epub 2007 Mar 21. PMID: 17369525. (Pubitemid 46842602)
35. Cases JA, Gabriely I, Ma XH, et al. Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo. Diabetes. 2001;50(2):348-52. Epub 2001 Mar 29. PMID: 11272146. (Pubitemid 32140441)
36. Considine RV, Sinha MK, Heiman ML, et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med. 1996;334(5):292-5. Epub 1996 Feb 01. PMID: 8532024. (Pubitemid 26033933)
37. Weyer C, Funahashi T, Tanaka S, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab. 2001;5(86):1930-5. Epub 2001 May 10. PMID: 11344187. (Pubitemid 32472900)
38. Yokota T, Oritani K, Takahashi I, et al. Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood. 2000;96(5):1723-32. Epub 2000 Sep 01. PMID: 10961870. (Pubitemid 30661055)
39. Degawa-Yamauchi M, Moss KA, Bovenkerk JE, et al. Regulation of adiponectin expression in human adipocytes: effects of adiposity, glucocorticoids, and tumor necrosis factor alpha. Obes Res. 2005;13(4):662-9. Epub 2005 Apr. PMID: 15897474.
40. Mohamed-Ali V, Goodrick S, Rawesh A, et al. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo. J Clin Endocrinol Metab. 1997;82(12):4196-200. Epub 1997 Dec. PMID: 9398739. (Pubitemid 27525539)
41. Rotter V, Nagaev I, Smith U. Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem. 2003;278(46):45777-84. Epub 2003 Nov 14. PMID: 12952969. (Pubitemid 37432722)
42. Hirosumi J, Tuncman G, Chang L, et al. A central role for JNK in obesity and insulin resistance. Nature. 2002;420(6913):333-6. Epub 2002 Nov 21. PMID: 12447443. (Pubitemid 35398190)
43. Zhang H, Wang Y, Zhang J, et al. Bariatric surgery reduces visceral adipose inflammation and improves endothelial function in type 2 diabetic mice. Arterioscler Thromb Vasc Biol. 2011;31(9):2063-9. Epub 2011 Sep. PMID: 21680898.
44. Illan-Gomez F, Gonzalvez-Ortega M, Orea-Soler I, et al. Obesity and inflammation: change in adiponectin, C-reactive protein, tumour necrosis factor-alpha and interleukin-6 after bariatric surgery. Obes Surg. 2012;22(6):950-5. Epub 2012 Apr 25. PMID: 22527592.
45. Curat CA, Miranville A, Sengenes C, et al. From blood monocytes to adipose tissue-resident macrophages: induction of diapedesis by human mature adipocytes. Diabetes. 2004;53(5):1285-92. Epub 2004 May. PMID: 15111498. (Pubitemid 38569015)
46. Lee HC, Kim MK, Kwon HS, et al. Early changes in incretin secretion after laparoscopic duodenal-jejunal bypass surgery in type 2 diabetic patients. Obes Surg. 2010;20(11):1530-5. Epub 2010 Aug 31. PMID: 20803098.
47. Lee YS, Park MS, Choung JS, et al. Glucagon-like peptide-1 inhibits adipose tissue macrophage infiltration and inflammation in an obese mouse model of diabetes. Diabetologia. 2012;55(9):2456-68. Epub 2012 Jun 23. PMID: 22722451.
48. Bruun JM, Lihn AS, Verdich C, et al. Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab. 2003;285(3):E527-33. Epub 2003 May 09. PMID: 12736161.
49. Feldstein AE, Werneburg NW, Canbay A, et al. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology. 2004;40(1):185-94. Epub 2004 Jul 09. PMID: 15239102. (Pubitemid 38868937)
50. Gastaldelli A. Abdominal fat: does it predict the development of type 2 diabetes? Am J Clin Nutr. 2008;87(5):1118-9. Epub 2008 May 13.PMID: 18469227. (Pubitemid 351679746)