Maternal folate depletion and high-fat feeding from weaning affects DNA methylation and DNA repair in brain of adult offspring

FASEB Journal

Volumn 27, Issue 8, 2013, Pages 3323-3334

  Langie, Sabine A S ^a,b   Achterfeldt, Sebastian ^a,b   Gorniak, Joanna P ^a,b   Halley Hogg, Kirstin J A ^a,b   Oxley, David ^c   Van Schooten, Frederik J ^d   Godschalk, Roger W L ^d   McKay, Jill A ^b   Mathers, John C ^a,b  

^a FLEMISH INSTITUTE FOR TECHNOLOGICAL RESEARCH VITO   (Belgium)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c BABRAHAM INSTITUTE   (United Kingdom)

^d MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Base excision repair; Developmental origin; Epigenetics

Indexed keywords

DNA; FOLIC ACID; 5 METHYLCYTOSINE; DNA BINDING PROTEIN; DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE; FAT INTAKE; NEIL1 PROTEIN, MOUSE; OGG1 PROTEIN, MOUSE; VITAMIN B COMPLEX; X-RAY REPAIR CROSS COMPLEMENTING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CEREBELLUM; CEREBELLUM CORTEX; CONTROLLED STUDY; DNA DAMAGE; DNA METHYLATION; DNA REPAIR; EXCISION REPAIR; FAT INTAKE; FEMALE; FOLIC ACID DEFICIENCY; GENE EXPRESSION; HIPPOCAMPUS; LACTATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PREGNANCY; PRIORITY JOURNAL; PROGENY; WEANING; ADMINISTRATION AND DOSAGE; ANIMAL; BRAIN; C57BL MOUSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIPID DIET; MALE; MATERNAL NUTRITION; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHARMACOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

5-METHYLCYTOSINE; ANIMALS; BASE SEQUENCE; BRAIN; DIET, HIGH-FAT; DIETARY FATS; DNA DAMAGE; DNA GLYCOSYLASES; DNA METHYLATION; DNA REPAIR; DNA-BINDING PROTEINS; FEMALE; FOLIC ACID; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VITAMIN B COMPLEX; WEANING;

EID: 84881168420     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-224121     Document Type: Article

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