Comparison of different methods of measuring 8-oxoguanine as a marker of oxidative DNA damage

Free Radical Research

Volumn 32, Issue 4, 2000, Pages 333-341

  Collins, Andrew ^a   Brown, J ^b   Bogdanov, M ^b   Cadet, J ^b   Cooke, M ^b   Douki, T ^b   Dunster, C ^b   Eakins, J ^b   Epe, B ^b   Evans, M ^b   Farmer, P ^b   Gedik, C M ^b   Halliwell, B ^b   Herbert, K ^b   Hofer, T ^b   Hutchinson, R ^b   Jenner, A ^b   Jones, G D D ^b   Kasai, H ^b   Kelly, F ^b   Lloret, A ^b   Loft, S ^b   Lunec, J ^b   McEwan, M ^b   Moller L ^b   Olinski, R ^b   Podmore, I ^b   Poulsen, H ^b   Ravanat, J L ^b   Rees, J E ^b   Reetz, F ^b   Shertzer, H ^b   Spiegelhalder, B ^b   Turesky, R ^b   Tyrrell, R ^b   Vina J ^b   Vinicombe, D ^b   Weimann, A ^b   de Wergifosse, B ^b   Wood, S G ^b   more..

^a ROWETT RESEARCH INSTITUTE   (United Kingdom)

^b NONE

Author keywords

8 hydroxy 2' deoxyguanosine; GC MS; HPLC; Methods validation; Oxidative DNA damage

Indexed keywords

8 HYDROXYGUANINE; CELL DNA;

ACCURACY; ANALYTIC METHOD; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA DETERMINATION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; OXIDATION; REPRODUCIBILITY;

EID: 0034065401     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760000300331     Document Type: Article

References (4)

1. A. Collins, J. Cadet, B. Epe and C. Gedik (1997) Problems in the measurement of 8-oxoguanine in human DNA. Report of a workshop, DNA Oxidation, held in Aberdeen, UK, 19-21 January, 1997. Carcinogenesis, 18, 1833-1836.
2. J. Lunec (1998) ESCODD: European Standards Committee on Oxidative DNA Damage. Free Radical Research, 29, 601-608.
3. S.G. Wood, C.M. Gedik and A.R. Collins (2000) Controlled oxidation of calf thymus DNA to produce standard samples for 8-oxo-deoxyguanosine analysis; effects of freeze-drying, storage and hydrolysis conditions. Free Radical Research, 32, 327-332.
4. C.M. Gedik, S.G. Wood and A.R. Collins (1998) Measuring oxidative damage to DNA; HPLC and the comet assay compared. Free Radical Research, 29, 609-615.