Pioglitazone retrieves hepatic antioxidant DNA repair in a mice model of high fat diet

BMC Molecular Biology

Volumn 9, Issue , 2008, Pages

  Hsiao, Pi Jung ^a   Hsieh, Tusty Jiuan ^a   Kuo, Kung Kai ^a   Hung, Wei Wen ^a   Tsai, Kun Bow ^a   Yang, Ching Hsiu ^a   Yu, Ming Lung ^a   Shin, Shyi Jang ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; 8 OXOGUANINE DNA GLYCOSYLASE 1; COPPER ZINC SUPEROXIDE DISMUTASE; DNA; DNA GLYCOSYLASE MUTY; DNA GLYCOSYLTRANSFERASE; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; PIOGLITAZONE; UNCLASSIFIED DRUG; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 8 HYDROXYGUANOSINE; 8-HYDROXYGUANOSINE; ANTIDIABETIC AGENT; ANTIOXIDANT; DRUG DERIVATIVE; GUANOSINE; OGG1 PROTEIN, MOUSE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FATTY LIVER; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; LIPID DIET; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CHEMISTRY; FAT INTAKE; LIVER CELL; METABOLISM; PATHOLOGY;

MUS;

ANIMALS; ANTIOXIDANTS; DIETARY FATS; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; FATTY LIVER; GUANOSINE; HEPATOCYTES; HYPOGLYCEMIC AGENTS; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED C57BL; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE; THIAZOLIDINEDIONES;

EID: 53749103612     PISSN: None     EISSN: 14712199     Source Type: Journal    
DOI: 10.1186/1471-2199-9-82     Document Type: Article

References (31)

1. Zafrani ES Non-alcoholic fatty liver disease: An emerging pathological spectrum Virchows Arch 2004, 444(1):3-12. 10.1007/s00428-003-0943-7 14685853
2. Grant LM Lisker-Melman M Nonalcoholic fatty liver disease Ann Hepatol 2004, 3(3):93-99. 15505593
3. Caldwell SH Chang CY Nakamoto RK Krugner-Higby L Mitochondria in nonalcoholic fatty liver disease Clin Liver Dis 2004, 8(3):595-617. 10.1016/j.cld.2004.04.009 15331066
4. Begriche K Igoudjil A Pessayre D Fromenty B Mitochondrial dysfunction in NASH: Causes, consequences and possible means to prevent it Mitochondrion 2006, 6(1):1-28. 10.1016/j.mito.2005.10.004 16406828
5. Browning JD Horton JD Molecular mediators of hepatic steatosis and liver injury J Clin Invest 2004, 114(2):147-152. 449757 15254578
6. Seki S Kitada T Sakaguchi H Clinicopathological significance of oxidative cellular damage in non-alcoholic fatty liver diseases Hepatol Res 2005, 33(2):132-134. 10.1016/j.hepres.2005.09.020 16198621
7. Norbury CJ Hickson ID Cellular responses to DNA damage Annu Rev Pharmacol Toxicol 2001, 41:367-401. 10.1146/annurev.pharmtox.41.1.367 11264462
8. Finkel T Holbrook NJ Oxidants, oxidative stress and the biology of ageing Nature 2000, 408(6809):239-247. 10.1038/35041687 11089981
9. Erker L Schubert R Elchuri S Huang TT Tarin D Mueller K Zielen S Epstein CJ Wynshaw-Boris A Effect of the reduction of superoxide dismutase 1 and 2 or treatment with alpha-tocopherol on tumorigenesis in Atm-deficient mice Free Radic Biol Med 2006, 41(4):590-600. 10.1016/ j.freeradbiomed.2006.04.032 16863992
10. Valko M Leibfritz D Moncol J Cronin MT Mazur M Telser J Free radicals and antioxidants in normal physiological functions and human disease Int J Biochem Cell Biol 2007, 39(1):44-84. 10.1016/j.biocel.2006.07.001 16978905
11. Bohr VA Stevnsner T de Souza-Pinto NC Mitochondrial DNA repair of oxidative damage in mammalian cells Gene 2002, 286(1):127-134. 10.1016/ S0378-1119(01)00813-7 11943468
12. Evans MD Cooke MS Factors contributing to the outcome of oxidative damage to nucleic acids Bioessays 2004, 26(5):533-542. 10.1002/ bies.20027 15112233
13. Larsen NB Rasmussen M Rasmussen LJ Nuclear and mitochondrial DNA repair: similar pathways? Mitochondrion 2005, 5(2):89-108. 10.1016/ j.mito.2005.02.002 16050976
14. Karahalil B Hogue BA de Souza-Pinto NC Bohr VA Base excision repair capacity in mitochondria and nuclei: Tissue-specific variations Faseb J 2002, 16(14):1895-1902. 10.1096/fj.02-0463com 12468454
15. Kota BP Huang TH Roufogalis BD An overview on biological mechanisms of PPARs Pharmacol Res 2005, 51(2):85-94. 10.1016/j.phrs.2004.07.012 15629253
16. Kopelovich L Fay JR Glazer RI Crowell JA Peroxisome proliferator-activated receptor modulators as potential chemopreventive agents Mol Cancer Ther 2002, 1(5):357-363. 12489852
17. Belfort R Harrison SA Brown K Darland C Finch J Hardies J Balas B Gastaldelli A Tio F Pulcini J A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis N Engl J Med 2006, 355(22):2297-2307. 10.1056/NEJMoa060326 17135584
18. Houstis N Rosen ED Lander ES Reactive oxygen species have a causal role in multiple forms of insulin resistance Nature 2006, 440(7086):944-948. 10.1038/nature04634 16612386
19. Kleiner DE Brunt EM Van Natta M Behling C Contos MJ Cummings OW Ferrell LD Liu YC Torbenson MS Unalp-Arida A Design and validation of a histological scoring system for nonalcoholic fatty liver disease Hepatology 2005, 41(6):1313-1321. 10.1002/hep.20701 15915461
20. Czaja MJ Cell signaling in oxidative stress-induced liver injury Semin Liver Dis 2007, 27(4):378-389. 10.1055/s-2007-991514 17979074
21. Djuric Z Lewis SM Lu MH Mayhugh M Tang N Hart RW Effect of varying dietary fat levels on rat growth and oxidative DNA damage Nutr Cancer 2001, 39(2):214-219. 10.1207/S15327914nc392_9 11759283
22. Carmiel-Haggai M Cederbaum AI Nieto N A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats Faseb J 2005, 19(1):136-138. 15522905
23. Milagro FI Campion J Martinez JA Weight gain induced by high-fat feeding involves increased liver oxidative stress Obesity (Silver Spring) 2006, 14(7):1118-1123. 10.1038/oby.2006.128 16899792
24. Fromenty B Robin MA Igoudjil A Mansouri A Pessayre D The ins and outs of mitochondrial dysfunction in NASH Diabetes Metab 2004, 30(2):121-138. 10.1016/S1262-3636(07)70098-8 15223984
25. Inoue M Ohtake T Motomura W Takahashi N Hosoki Y Miyoshi S Suzuki Y Saito H Kohgo Y Okumura T Increased expression of PPARgamma in high fat diet-induced liver steatosis in mice Biochem Biophys Res Commun 2005, 336(1):215-222. 10.1016/j.bbrc.2005.08.070 16125673
26. Yu S Matsusue K Kashireddy P Cao WQ Yeldandi V Yeldandi AV Rao MS Gonzalez FJ Reddy JK Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression J Biol Chem 2003, 278(1):498-505. 10.1074/jbc.M210062200 12401792
27. Gavrilova O Haluzik M Matsusue K Cutson JJ Johnson L Dietz KR Nicol CJ Vinson C Gonzalez FJ Reitman ML Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass J Biol Chem 2003, 278(36):34268-34276. 10.1074/jbc.M300043200 12805374
28. Lutchman G Promrat K Kleiner DE Heller T Ghany MG Yanovski JA Liang TJ Hoofnagle JH Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: Relationship to histological improvement Clin Gastroenterol Hepatol 2006, 4(8):1048-1052. 10.1016/ j.cgh.2006.05.005 16814613
29. Takeshita Y Takamura T Hamaguchi E Shimizu A Ota T Sakurai M Kaneko S Tumor necrosis factor-alpha-induced production of plasminogen activator inhibitor 1 and its regulation by pioglitazone and cerivastatin in a nonmalignant human hepatocyte cell line Metabolism 2006, 55(11):1464-1472. 10.1016/j.metabol.2006.06.016 17046548
30. Gumieniczek A Effect of the new thiazolidinedione-pioglitazone on the development of oxidative stress in liver and kidney of diabetic rabbits Life Sci 2003, 74(5):553-562. 10.1016/j.lfs.2003.03.004 14623026
31. Chaudhry J Ghosh NN Roy K Chandra R Antihyperglycemic effect of a new thiazolidinedione analogue and its role in ameliorating oxidative stress in alloxan-induced diabetic rats Life Sci 2007, 80(12):1135-1142. 10.1016/j.lfs.2006.12.004 17234217