-
1
-
-
67651171392
-
Hsp90 is an essential regulator of EphA2 receptor stability and signaling: Implications for cancer cell migration and metastasis
-
Annamalai B, Liu X, Gopal U, Isaacs JS (2009). Hsp90 is an essential regulator of EphA2 receptor stability and signaling: implications for cancer cell migration and metastasis. Mol Cancer Res 7, 1021-1032.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1021-1032
-
-
Annamalai, B.1
Liu, X.2
Gopal, U.3
Isaacs, J.S.4
-
2
-
-
0034777916
-
Destabilization of steroid receptors by heat shock protein 90-binding drugs: A ligand-independent approach to hormonal therapy of breast cancer
-
Bagatell R, Khan O, Paine-Murrieta G, Taylor CW, Akinaga S, Whitesell L (2001). Destabilization of steroid receptors by heat shock protein 90-binding drugs: a ligand-independent approach to hormonal therapy of breast cancer. Clin Cancer Res 7, 2076-2084.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2076-2084
-
-
Bagatell, R.1
Khan, O.2
Paine-Murrieta, G.3
Taylor, C.W.4
Akinaga, S.5
Whitesell, L.6
-
3
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ (2001). Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409, 363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
4
-
-
0029145215
-
Geldanamycin selectively destabilizes and conformationally alters mutated p53
-
Blagosklonny MV, Toretsky J, Neckers L (1995). Geldanamycin selectively destabilizes and conformationally alters mutated p53. Oncogene 11, 933-939.
-
(1995)
Oncogene
, vol.11
, pp. 933-939
-
-
Blagosklonny, M.V.1
Toretsky, J.2
Neckers, L.3
-
5
-
-
38549173606
-
The bio GRID interaction database: 2008 update
-
Breitkreutz BJ et al. (2008). The Bio GRID Interaction Database: 2008 update. Nucleic Acids Res 36, D637-D640.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Breitkreutz, B.J.1
-
7
-
-
0030869037
-
Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70
-
Dittmar KD, Demady DR, Stancato LF, Krishna P, Pratt WB (1997). Folding of the glucocorticoid receptor by the heat shock protein (hsp) 90-based chaperone machinery. The role of p23 is to stabilize receptor.hsp90 heterocomplexes formed by hsp90.p60.hsp70. J Biol Chem 272, 21213-21220.
-
(1997)
J Biol Chem
, vol.272
, pp. 21213-21220
-
-
Dittmar, K.D.1
Demady, D.R.2
Stancato, L.F.3
Krishna, P.4
Pratt, W.B.5
-
8
-
-
79551627496
-
A parsimonious model for gene regulation by miRNAs
-
Djuranovic S, Nahvi A, Green R (2011). A parsimonious model for gene regulation by miRNAs. Science 331, 550-553.
-
(2011)
Science
, vol.331
, pp. 550-553
-
-
Djuranovic, S.1
Nahvi, A.2
Green, R.3
-
9
-
-
0030692139
-
All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae
-
Dolinski K, Muir S, Cardenas M, Heitman J (1997). All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 94, 13093-13098.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13093-13098
-
-
Dolinski, K.1
Muir, S.2
Cardenas, M.3
Heitman, J.4
-
10
-
-
80055092838
-
Binding of the cyclophilin 40 ortholog SQUINT to Hsp90 protein is required for SQUINT function in Arabidopsis
-
Earley KW, Poethig RS (2011). Binding of the cyclophilin 40 ortholog SQUINT to Hsp90 protein is required for SQUINT function in Arabidopsis. J Biol Chem 286, 38184-38189.
-
(2011)
J Biol Chem
, vol.286
, pp. 38184-38189
-
-
Earley, K.W.1
Poethig, R.S.2
-
11
-
-
0035863097
-
RNA interference is mediated by 21-and 22-nucleotide RNAs
-
Elbashir SM, Lendeckel W, Tuschl T (2001a). RNA interference is mediated by 21-and 22-nucleotide RNAs. Genes Dev 15, 188-200.
-
(2001)
Genes Dev
, vol.15
, pp. 188-200
-
-
Elbashir, S.M.1
Lendeckel, W.2
Tuschl, T.3
-
12
-
-
0035803583
-
Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate
-
Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschl T (2001b). Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate. EMBO J 20, 6877-6888.
-
(2001)
EMBO J
, vol.20
, pp. 6877-6888
-
-
Elbashir, S.M.1
Martinez, J.2
Patkaniowska, A.3
Lendeckel, W.4
Tuschl, T.5
-
13
-
-
77953140972
-
Argonaute proteins at a glance
-
Ender C, Meister G (2010). Argonaute proteins at a glance. J Cell Sci 123, 1819-1823.
-
(2010)
J Cell Sci
, vol.123
, pp. 1819-1823
-
-
Ender, C.1
Meister, G.2
-
14
-
-
77953629046
-
Regulation of mRNA translation and stability by microRNAs
-
Fabian MR, Sonenberg N, Filipowicz W (2010). Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 79, 351-379.
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 351-379
-
-
Fabian, M.R.1
Sonenberg, N.2
Filipowicz, W.3
-
15
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman RC, Farh KK, Burge CB, Bartel DP (2009). Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19, 92-105.
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
16
-
-
0029017132
-
Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins
-
Gerber MR, Farrell A, Deshaies RJ, Herskowitz I, Morgan DO (1995). Cdc37 is required for association of the protein kinase Cdc28 with G1 and mitotic cyclins. Proc Natl Acad Sci USA 92, 4651-4655.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4651-4655
-
-
Gerber, M.R.1
Farrell, A.2
Deshaies, R.J.3
Herskowitz, I.4
Morgan, D.O.5
-
17
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
-
Hammond SM, Bernstein E, Beach D, Hannon GJ (2000). An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404, 293-296.
-
(2000)
Nature
, vol.404
, pp. 293-296
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
18
-
-
18844406200
-
Aha1 competes with Hop, p50 and p23 for binding to the molecular chaperone Hsp90 and contributes to kinase and hormone receptor activation
-
Harst A, Lin H, Obermann WM (2005). Aha1 competes with Hop, p50 and p23 for binding to the molecular chaperone Hsp90 and contributes to kinase and hormone receptor activation. Biochem J 387, 789-796.
-
(2005)
Biochem J
, vol.387
, pp. 789-796
-
-
Harst, A.1
Lin, H.2
Obermann, W.M.3
-
19
-
-
0034720777
-
P50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules
-
Hartson SD, Irwin AD, Shao J, Scroggins BT, Volk L, Huang W, Matts RL (2000). p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules. Biochemistry 39, 7631-7644.
-
(2000)
Biochemistry
, vol.39
, pp. 7631-7644
-
-
Hartson, S.D.1
Irwin, A.D.2
Shao, J.3
Scroggins, B.T.4
Volk, L.5
Huang, W.6
Matts, R.L.7
-
20
-
-
61949349758
-
Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90
-
Hessling M, Richter K, Buchner J (2009). Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90. Nat Struct Mol Biol 16, 287-293.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 287-293
-
-
Hessling, M.1
Richter, K.2
Buchner, J.3
-
21
-
-
84879531857
-
Akt-mediated phosphorylation of Argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets
-
Horman SR et al. (2013). Akt-mediated phosphorylation of Argonaute 2 downregulates cleavage and upregulates translational repression of MicroRNA targets. Mol Cell 50, 356-367.
-
(2013)
Mol Cell
, vol.50
, pp. 356-367
-
-
Horman, S.R.1
-
22
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD (2001). A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 393, 834-838.
-
(2001)
Science
, vol.393
, pp. 834-838
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
Balint, E.4
Tuschl, T.5
Zamore, P.D.6
-
23
-
-
77955479987
-
In vitro assembly of plant RNA-induced silencing complexes facilitated by molecular chaperone HSP90
-
Iki T, Yoshikawa M, Nishikiori M, Jaudal MC, Matsumoto-Yokoyama E, Mitsuhara I, Meshi T, Ishikawa M (2010). In vitro assembly of plant RNA-induced silencing complexes facilitated by molecular chaperone HSP90. Mol Cell 39, 282-291.
-
(2010)
Mol Cell
, vol.39
, pp. 282-291
-
-
Iki, T.1
Yoshikawa, M.2
Nishikiori, M.3
Jaudal, M.C.4
Matsumoto-Yokoyama, E.5
Mitsuhara, I.6
Meshi, T.7
Ishikawa, M.8
-
24
-
-
77955478739
-
Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes
-
Iwasaki S, Kobayashi M, Yoda M, Sakaguchi Y, Katsuma S, Suzuki T, Tomari Y (2010). Hsc70/Hsp90 chaperone machinery mediates ATP-dependent RISC loading of small RNA duplexes. Mol Cell 39, 292-299.
-
(2010)
Mol Cell
, vol.39
, pp. 292-299
-
-
Iwasaki, S.1
Kobayashi, M.2
Yoda, M.3
Sakaguchi, Y.4
Katsuma, S.5
Suzuki, T.6
Tomari, Y.7
-
25
-
-
77951712353
-
HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells
-
Johnston M, Geoffroy MC, Sobala A, Hay R, Hutvagner G (2010). HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells. Mol Biol Cell 21, 1462-1469.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1462-1469
-
-
Johnston, M.1
Geoffroy, M.C.2
Sobala, A.3
Hay, R.4
Hutvagner, G.5
-
26
-
-
79953324542
-
Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90
-
Jung G, Barylko B, Lu D, Shu H, Yin H, Albanesi JP (2011). Stabilization of phosphatidylinositol 4-kinase type IIbeta by interaction with Hsp90. J Biol Chem 286, 12775-12784.
-
(2011)
J Biol Chem
, vol.286
, pp. 12775-12784
-
-
Jung, G.1
Barylko, B.2
Lu, D.3
Shu, H.4
Yin, H.5
Albanesi, J.P.6
-
27
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. Elegans
-
Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ, Plasterk RH (2001). Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev 15, 2654-2659.
-
(2001)
Genes Dev
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.6
-
28
-
-
84862743241
-
A daphnane diterpenoid isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity
-
Khong A et al. (2012). A daphnane diterpenoid isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity. PLoS One 7, e39621.
-
(2012)
PLoS One
, vol.7
-
-
Khong, A.1
-
29
-
-
0030745769
-
Cdc37 is a molecular chaperone with specific functions in signal transduction
-
Kimura Y, Rutherford SL, Miyata Y, Yahara I, Freeman BC, Yue L, Morimoto RI, Lindquist S (1997). Cdc37 is a molecular chaperone with specific functions in signal transduction. Genes Dev 11, 1775-1785.
-
(1997)
Genes Dev
, vol.11
, pp. 1775-1785
-
-
Kimura, Y.1
Rutherford, S.L.2
Miyata, Y.3
Yahara, I.4
Freeman, B.C.5
Yue, L.6
Morimoto, R.I.7
Lindquist, S.8
-
30
-
-
77949438155
-
Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis
-
Koulov AV et al. (2010). Biological and structural basis for Aha1 regulation of Hsp90 ATPase activity in maintaining proteostasis in the human disease cystic fibrosis. Mol Biol Cell 21, 871-884.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 871-884
-
-
Koulov, A.V.1
-
31
-
-
33845295461
-
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules
-
Leung AK, Calabrese JM, Sharp PA (2006). Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci USA 103, 18125-18130.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18125-18130
-
-
Leung, A.K.1
Calabrese, J.M.2
Sharp, P.A.3
-
32
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP (2005). Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
33
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu J, Carmell MA, Rivas FV, Marsden CG, Thomson JM, Song JJ, Hammond SM, Joshua-Tor L, Hannon GJ (2004). Argonaute2 is the catalytic engine of mammalian RNAi. Science 305, 1437-1441.
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
34
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez J, Patkaniowska A, Urlaub H, Luhrmann R, Tuschl T (2002). Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 110, 563-574.
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
35
-
-
84876532060
-
Argonaute2 expression is post-transcriptionally coupled to microRNA abundance
-
Martinez NJ, Gregory RI (2013). Argonaute2 expression is post-transcriptionally coupled to microRNA abundance. RNA 19, 605-612.
-
(2013)
RNA
, vol.19
, pp. 605-612
-
-
Martinez, N.J.1
Gregory, R.I.2
-
36
-
-
31344474558
-
The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins
-
McLaughlin SH, Sobott F, Yao ZP, Zhang W, Nielsen PR, Grossmann JG, Laue ED, Robinson CV, Jackson SE (2006). The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins. J Mol Biol 356, 746-758.
-
(2006)
J Mol Biol
, vol.356
, pp. 746-758
-
-
McLaughlin, S.H.1
Sobott, F.2
Yao, Z.P.3
Zhang, W.4
Nielsen, P.R.5
Grossmann, J.G.6
Laue, E.D.7
Robinson, C.V.8
Jackson, S.E.9
-
37
-
-
3242736704
-
Human argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs
-
Meister G, Landthaler M, Patkaniowska A, Dorsett Y, Teng G, Tuschl T (2004). Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell 15, 185-197.
-
(2004)
Mol Cell
, vol.15
, pp. 185-197
-
-
Meister, G.1
Landthaler, M.2
Patkaniowska, A.3
Dorsett, Y.4
Teng, G.5
Tuschl, T.6
-
38
-
-
77955426711
-
A direct role for Hsp90 in pre-RISC formation in Drosophila
-
Miyoshi T, Takeuchi A, Siomi H, Siomi MC (2010). A direct role for Hsp90 in pre-RISC formation in Drosophila. Nat Struct Mol Biol 17, 1024-1026.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1024-1026
-
-
Miyoshi, T.1
Takeuchi, A.2
Siomi, H.3
Siomi, M.C.4
-
39
-
-
1342294313
-
The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: Hsp90 complex
-
Morishima Y, Kanelakis KC, Murphy PJ, Lowe ER, Jenkins GJ, Osawa Y, Sunahara RK, Pratt WB (2003). The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex. J Biol Chem 278, 48754-48763.
-
(2003)
J Biol Chem
, vol.278
, pp. 48754-48763
-
-
Morishima, Y.1
Kanelakis, K.C.2
Murphy, P.J.3
Lowe, E.R.4
Jenkins, G.J.5
Osawa, Y.6
Sunahara, R.K.7
Pratt, W.B.8
-
40
-
-
0032538995
-
In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis
-
Obermann WM, Sondermann H, Russo AA, Pavletich NP, Hartl FU (1998). In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J Cell Biol 143, 901-910.
-
(1998)
J Cell Biol
, vol.143
, pp. 901-910
-
-
Obermann, W.M.1
Sondermann, H.2
Russo, A.A.3
Pavletich, N.P.4
Hartl, F.U.5
-
41
-
-
0032541344
-
ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo
-
Panaretou B, Prodromou C, Roe SM, O'Brien R, Ladbury JE, Piper PW, Pearl LH (1998). ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo. EMBO J 17, 4829-4836.
-
(1998)
EMBO J
, vol.17
, pp. 4829-4836
-
-
Panaretou, B.1
Prodromou, C.2
Roe, S.M.3
O'Brien, R.4
Ladbury, J.E.5
Piper, P.W.6
Pearl, L.H.7
-
42
-
-
0036931438
-
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1
-
Panaretou B et al. (2002). Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. Mol Cell 10, 1307-1318.
-
(2002)
Mol Cell
, vol.10
, pp. 1307-1318
-
-
Panaretou, B.1
-
43
-
-
80051564261
-
Live cell imaging of Argonaute proteins in mammalian cells
-
Pare JM, Lopez-Orozco J, Hobman TC (2011). Live cell imaging of Argonaute proteins in mammalian cells. Methods Mol Biol 725, 161-172.
-
(2011)
Methods Mol Biol
, vol.725
, pp. 161-172
-
-
Pare, J.M.1
Lopez-Orozco, J.2
Hobman, T.C.3
-
44
-
-
67749145232
-
Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies
-
Pare JM, Tahbaz N, Lopez-Orozco J, LaPointe P, Lasko P, Hobman TC (2009). Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies. Mol Biol Cell 20, 3273-3284.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 3273-3284
-
-
Pare, J.M.1
Tahbaz, N.2
Lopez-Orozco, J.3
Lapointe, P.4
Lasko, P.5
Hobman, T.C.6
-
45
-
-
12344291243
-
Hsp90 and Cdc37-A chaperone cancer conspiracy
-
Pearl LH (2005). Hsp90 and Cdc37-a chaperone cancer conspiracy. Curr Opin Genet Dev 15, 55-61.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 55-61
-
-
Pearl, L.H.1
-
46
-
-
0026495863
-
Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes
-
Peattie DA, Harding MW, Fleming MA, DeCenzo MT, Lippke JA, Livingston DJ, Benasutti M (1992). Expression and characterization of human FKBP52, an immunophilin that associates with the 90-kDa heat shock protein and is a component of steroid receptor complexes. Proc Natl Acad Sci USA 89, 10974-10978.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10974-10978
-
-
Peattie, D.A.1
Harding, M.W.2
Fleming, M.A.3
Decenzo, M.T.4
Lippke, J.A.5
Livingston, D.J.6
Benasutti, M.7
-
47
-
-
3142550874
-
Role of molecular chaperones in steroid receptor action
-
Pratt WB, Galigniana MD, Morishima Y, Murphy PJ (2004). Role of molecular chaperones in steroid receptor action. Essays Biochem 40, 41-58.
-
(2004)
Essays Biochem
, vol.40
, pp. 41-58
-
-
Pratt, W.B.1
Galigniana, M.D.2
Morishima, Y.3
Murphy, P.J.4
-
48
-
-
27744562164
-
Cdk2: A genuine protein kinase client of Hsp90 and Cdc37
-
Prince T, Sun L, Matts RL (2005). Cdk2: a genuine protein kinase client of Hsp90 and Cdc37. Biochemistry 44, 15287-15295.
-
(2005)
Biochemistry
, vol.44
, pp. 15287-15295
-
-
Prince, T.1
Sun, L.2
Matts, R.L.3
-
49
-
-
0034663806
-
The ATPase cycle of Hsp90 drives a molecular "clamp" via transient dimerization of the N-terminal domains
-
Prodromou C, Panaretou B, Chohan S, Siligardi G, O'Brien R, Ladbury JE, Roe SM, Piper PW, Pearl LH (2000). The ATPase cycle of Hsp90 drives a molecular "clamp" via transient dimerization of the N-terminal domains. EMBO J 19, 4383-4392.
-
(2000)
EMBO J
, vol.19
, pp. 4383-4392
-
-
Prodromou, C.1
Panaretou, B.2
Chohan, S.3
Siligardi, G.4
O'Brien, R.5
Ladbury, J.E.6
Roe, S.M.7
Piper, P.W.8
Pearl, L.H.9
-
50
-
-
4444291743
-
The co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle
-
Richter K, Walter S, Buchner J (2004). The co-chaperone Sba1 connects the ATPase reaction of Hsp90 to the progression of the chaperone cycle. J Mol Biol 342, 1403-1413.
-
(2004)
J Mol Biol
, vol.342
, pp. 1403-1413
-
-
Richter, K.1
Walter, S.2
Buchner, J.3
-
51
-
-
0037416154
-
The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo
-
Riggs DL, Roberts PJ, Chirillo SC, Cheung-Flynn J, Prapapanich V, Ratajczak T, Gaber R, Picard D, Smith DF (2003). The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo. EMBO J 22, 1158-1167.
-
(2003)
EMBO J
, vol.22
, pp. 1158-1167
-
-
Riggs, D.L.1
Roberts, P.J.2
Chirillo, S.C.3
Cheung-Flynn, J.4
Prapapanich, V.5
Ratajczak, T.6
Gaber, R.7
Picard, D.8
Smith, D.F.9
-
52
-
-
79953682552
-
Phosphorylation of human Argonaute proteins affects small RNA binding
-
Rudel S, Wang Y, Lenobel R, Korner R, Hsiao HH, Urlaub H, Patel D, Meister G (2011). Phosphorylation of human Argonaute proteins affects small RNA binding. Nucleic Acids Res 39, 2330-2343.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 2330-2343
-
-
Rudel, S.1
Wang, Y.2
Lenobel, R.3
Korner, R.4
Hsiao, H.H.5
Urlaub, H.6
Patel, D.7
Meister, G.8
-
53
-
-
77953702889
-
A functional RNAi screen identifies hexokinase 1 as a modifier of type II apoptosis
-
Schindler A, Foley E (2010). A functional RNAi screen identifies hexokinase 1 as a modifier of type II apoptosis. Cell Signal 22, 1330-1340.
-
(2010)
Cell Signal
, vol.22
, pp. 1330-1340
-
-
Schindler, A.1
Foley, E.2
-
54
-
-
0036752955
-
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
-
Schwarz DS, Hutvagner G, Haley B, Zamore PD (2002). Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol Cell 10, 537-548.
-
(2002)
Mol Cell
, vol.10
, pp. 537-548
-
-
Schwarz, D.S.1
Hutvagner, G.2
Haley, B.3
Zamore, P.D.4
-
55
-
-
33750008686
-
Structural analysis of E. Coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements
-
Shiau AK, Harris SF, Southworth DR, Agard DA (2006). Structural analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements. Cell 127, 329-340.
-
(2006)
Cell
, vol.127
, pp. 329-340
-
-
Shiau, A.K.1
Harris, S.F.2
Southworth, D.R.3
Agard, D.A.4
-
56
-
-
10644265069
-
Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle
-
Siligardi G, Hu B, Panaretou B, Piper PW, Pearl LH, Prodromou C (2004). Co-chaperone regulation of conformational switching in the Hsp90 ATPase cycle. J Biol Chem 279, 51989-51998.
-
(2004)
J Biol Chem
, vol.279
, pp. 51989-51998
-
-
Siligardi, G.1
Hu, B.2
Panaretou, B.3
Piper, P.W.4
Pearl, L.H.5
Prodromou, C.6
-
57
-
-
0027439595
-
Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70
-
Smith DF, Sullivan WP, Marion TN, Zaitsu K, Madden B, McCormick DJ, Toft DO (1993). Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70. Mol Cell Biol 13, 869-876.
-
(1993)
Mol Cell Biol
, vol.13
, pp. 869-876
-
-
Smith, D.F.1
Sullivan, W.P.2
Marion, T.N.3
Zaitsu, K.4
Madden, B.5
McCormick, D.J.6
Toft, D.O.7
-
58
-
-
0029665779
-
Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4
-
Stepanova L, Leng X, Parker SB, Harper JW (1996). Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4. Genes Dev 10, 1491-1502.
-
(1996)
Genes Dev
, vol.10
, pp. 1491-1502
-
-
Stepanova, L.1
Leng, X.2
Parker, S.B.3
Harper, J.W.4
-
59
-
-
1642487115
-
Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer
-
Tahbaz N, Kolb FA, Zhang H, Jaronczyk K, Filipowicz W, Hobman TC (2004). Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer. EMBO Rep 5, 189-194.
-
(2004)
EMBO Rep
, vol.5
, pp. 189-194
-
-
Tahbaz, N.1
Kolb, F.A.2
Zhang, H.3
Jaronczyk, K.4
Filipowicz, W.5
Hobman, T.C.6
-
60
-
-
77953916528
-
HSP90 at the hub of protein homeostasis: Emerging mechanistic insights
-
Taipale M, Jarosz DF, Lindquist S (2010). HSP90 at the hub of protein homeostasis: emerging mechanistic insights. Nat Rev Mol Cell Biol 11, 515-528.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 515-528
-
-
Taipale, M.1
Jarosz, D.F.2
Lindquist, S.3
-
62
-
-
34249944855
-
Geldanamycin destabilizes HER2 tyrosine kinase and suppresses Wnt/beta-catenin signaling in HER2 overexpressing human breast cancer cells
-
Wang K, Ma Q, Ren Y, He J, Zhang Y, Zhang Y, Chen W (2007). Geldanamycin destabilizes HER2 tyrosine kinase and suppresses Wnt/beta-catenin signaling in HER2 overexpressing human breast cancer cells. Oncol Rep 17, 89-96.
-
(2007)
Oncol Rep
, vol.17
, pp. 89-96
-
-
Wang, K.1
Ma, Q.2
Ren, Y.3
He, J.4
Zhang, Y.5
Zhang, Y.6
Chen, W.7
-
63
-
-
33750842131
-
Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis
-
Wang X et al. (2006). Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. Cell 127, 803-815.
-
(2006)
Cell
, vol.127
, pp. 803-815
-
-
Wang, X.1
-
64
-
-
57749206034
-
Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex
-
Wang Y, Juranek S, Li H, Sheng G, Tuschl T, Patel DJ (2008a). Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature 456, 921-926.
-
(2008)
Nature
, vol.456
, pp. 921-926
-
-
Wang, Y.1
Juranek, S.2
Li, H.3
Sheng, G.4
Tuschl, T.5
Patel, D.J.6
-
65
-
-
56249145105
-
Structure of the guide-strand-containing argonaute silencing complex
-
Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ (2008b). Structure of the guide-strand-containing argonaute silencing complex. Nature 456, 209-213.
-
(2008)
Nature
, vol.456
, pp. 209-213
-
-
Wang, Y.1
Sheng, G.2
Juranek, S.3
Tuschl, T.4
Patel, D.J.5
-
66
-
-
14244262261
-
FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells
-
Wochnik GM, Ruegg J, Abel GA, Schmidt U, Holsboer F, Rein T (2005). FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells. J Biol Chem 280, 4609-4616.
-
(2005)
J Biol Chem
, vol.280
, pp. 4609-4616
-
-
Wochnik, G.M.1
Ruegg, J.2
Abel, G.A.3
Schmidt, U.4
Holsboer, F.5
Rein, T.6
-
67
-
-
48249114811
-
Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies
-
Zeng Y, Sankala H, Zhang X, Graves PR (2008). Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies. Biochem J 413, 429-436.
-
(2008)
Biochem J
, vol.413
, pp. 429-436
-
-
Zeng, Y.1
Sankala, H.2
Zhang, X.3
Graves, P.R.4
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