Argonaute proteins at a glance

Journal of Cell Science

Volumn 123, Issue 11, 2010, Pages 1819-1823

  Ender, Christine ^a   Meister, Gunter ^a,b  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARGONAUTE 1 PROTEIN; ARGONAUTE 3 PROTEIN; ARGONAUTE PROTEIN; DICER; DOUBLE STRANDED RNA; HISTONE; MESSENGER RNA; MICRORNA; PIWI INTERACTING RNA; RIBONUCLEASE III; RNA BINDING PROTEIN; RNA INDUCED SILENCING COMPLEX; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; UNTRANSLATED RNA; INITIATION FACTOR; PROTEIN BINDING;

5' UNTRANSLATED REGION; BIOGENESIS; CELL FUNCTION; CELL NUCLEUS; DNA METHYLATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; GENETIC CODE; GENETIC TRANSCRIPTION; HUMAN; INTRON; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; RNA SEQUENCE; RNA STABILITY; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSGENE; TRANSPOSON; ANIMAL; CLASSIFICATION; GENETICS; METABOLISM; PROTEIN CONFORMATION;

ANIMALS; EUKARYOTIC INITIATION FACTORS; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 77953140972     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.055210     Document Type: Review

References (57)

1. Aravin, A. A. and Hannon, G. J. (2008). Small RNA silencing pathways in germ and stem cells. Cold Spring Harbor Symp. Quant. Biol. 73, 283-290.
2. Bagga, S., Bracht, J., Hunter, S., Massirer, K., Holtz, J., Eachus, R. and Pasquinelli, A. E. (2005). Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 122, 553-563.
3. Behm-Ansmant, I., Rehwinkel, J., Doerks, T., Stark, A., Bork, P. and Izaurralde, E. (2006). mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev. 20, 1885-1898.
4. Beilharz, T. H., Humphreys, D. T., Clancy, J. L., Thermann, R., Martin, D. I., Hentze, M. W. and Preiss, T. (2009). microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells. PLoS ONE 4, e6783.
5. Bohmert, K., Camus, I., Bellini, C., Bouchez, D., Caboche, M. and Benning, C. (1998). AGO1 defines a novel locus of Arabidopsis controlling leaf development. EMBO J. 17, 170-180.
6. Brennecke, J., Malone, C. D., Aravin, A. A., Sachidanandam, R., Stark, A. and Hannon, G. J. (2008). An epigenetic role for maternally inherited piRNAs in transposon silencing. Science 322, 1387-1392.
7. Carthew, R. W. and Sontheimer, E. J. (2009). Origins and mechanisms of miRNAs and siRNAs. Cell 136, 642-655.
8. Czech, B., Malone, C. D., Zhou, R., Stark, A., Schlingeheyde, C., Dus, M., Perrimon, N., Kellis, M., Wohlschlegel, J. A., Sachidanandam, R. et al. (2008). An endogenous small interfering RNA pathway in Drosophila. Nature 453, 798-802.
9. Drinnenberg, I. A., Weinberg, D. E., Xie, K. T., Mower, J. P., Wolfe, K. H., Fink, G. R. and Bartel, D. P. (2009). RNAi in budding yeast. Science 326, 544-550.
10. Ender, C., Krek, A., Friedlander, M. R., Beitzinger, M., Weinmann, L., Chen, W., Pfeffer, S., Rajewsky, N. and Meister, G. (2008). A human snoRNA with microRNA-like functions. Mol. Cell 32, 519-528.
11. Eulalio, A., Behm-Ansmant, I. and Izaurralde, E. (2007). P bodies: at the crossroads of post-transcriptional pathways. Nat. Rev. Mol. Cell Biol. 8, 9-22.
12. Eulalio, A., Huntzinger, E. and Izaurralde, E. (2008a). Getting to the root of miRNA-mediated gene silencing. Cell 132, 9-14.
13. Eulalio, A., Huntzinger, E. and Izaurralde, E. (2008b). GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nat. Struct. Mol. Biol. 15, 346-353.
14. Fabian, M. R., Mathonnet, G., Sundermeier, T., Mathys, H., Zipprich, J. T., Svitkin, Y. V., Rivas, F., Jinek, M., Wohlschlegel, J., Doudna, J. A. et al. (2009). Mammalian miRNA RISC recruits CAF1 and PABP to affect PABPdependent deadenylation. Mol. Cell 35, 868-880.
15. Filipowicz, W., Bhattacharyya, S. N. and Sonenberg, N. (2008). Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet. 9, 102-114.
16. Ghildiyal, M., Seitz, H., Horwich, M. D., Li, C., Du, T., Lee, S., Xu, J., Kittler, E. L., Zapp, M. L., Weng, Z. et al. (2008). Endogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells. Science 320, 1077-1081.
17. Giraldez, A. J., Mishima, Y., Rihel, J., Grocock, R. J., Van Dongen, S., Inoue, K., Enright, A. J. and Schier, A. F. (2006). Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science 312, 75-79.
18. Jakymiw, A., Lian, S., Eystathioy, T., Li, S., Satoh, M., Hamel, J. C., Fritzler, M. J. and Chan, E. K. (2005). Disruption of GW bodies impairs mammalian RNA interference. Nat. Cell Biol. 7, 1267-1274.
19. Janowski, B. A., Huffman, K. E., Schwartz, J. C., Ram, R., Nordsell, R., Shames, D. S., Minna, J. D. and Corey, D. R. (2006). Involvement of AGO1 and AGO2 in mammalian transcriptional silencing. Nat. Struct. Mol. Biol. 13, 787-792.
20. Janowski, B. A., Younger, S. T., Hardy, D. B., Ram, R., Huffman, K. E. and Corey, D. R. (2007). Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nat. Chem. Biol. 3, 166-173.
21. Jinek, M. and Doudna, J. A. (2009). A three-dimensional view of the molecular machinery of RNA interference. Nature 457, 405-412.
22. Kawamura, Y., Saito, K., Kin, T., Ono, Y., Asai, K., Sunohara, T., Okada, T. N., Siomi, M. C. and Siomi, H. (2008). Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells. Nature 453, 793-797.
23. Kim, D. H., Villeneuve, L. M., Morris, K. V. and Rossi, J. J. (2006). Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat. Struct. Mol. Biol. 13, 793-797.
24. Kim, D. H., Saetrom, P., Snove, O., Jr and Rossi, J. J. (2008). MicroRNA-directed transcriptional gene silencing in mammalian cells. Proc. Natl. Acad. Sci. USA 105, 16230-16235.
25. Kim, V. N., Han, J. and Siomi, M. C. (2009). Biogenesis of small RNAs in animals. Nat. Rev. Mol. Cell Biol. 10, 126-139.
26. Kirino, Y., Kim, N., de Planell-Saguer, M., Khandros, E., Chiorean, S., Klein, P. S., Rigoutsos, I., Jongens, T. A. and Mourelatos, Z. (2009). Arginine methylation of Piwi proteins catalysed by dPRMT5 is required for Ago3 and Aub stability. Nat. Cell Biol. 11, 652-658.
27. Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., Song, J. J., Hammond, S. M., Joshua-Tor, L. and Hannon, G. J. (2004). Argonaute2 is the catalytic engine of mammalian RNAi. Science 305, 1437-1441.
28. Liu, J., Rivas, F. V., Wohlschlegel, J., Yates, J. R., 3rd, Parker, R. and Hannon, G. J. (2005). A role for the P-body component GW182 in microRNA function. Nat. Cell Biol. 7, 1161-1166.
29. Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G. and Tuschl, T. (2004). Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol. Cell 15, 185-197.
30. Meister, G., Landthaler, M., Peters, L., Chen, P. Y., Urlaub, H., Luhrmann, R. and Tuschl, T. (2005). Identification of novel argonaute-associated proteins. Curr. Biol. 15, 2149-2155.
31. Moazed, D. (2009). Small RNAs in transcriptional gene silencing and genome defence. Nature 457, 413-420.
32. Okamura, K. and Lai, E. C. (2008). Endogenous small interfering RNAs in animals. Nat. Rev. Mol. Cell Biol. 9, 673-678.
33. Okamura, K., Chung, W. J., Ruby, J. G., Guo, H., Bartel, D. P. and Lai, E. C. (2008). The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs. Nature 453, 803-806.
34. Packer, A. N., Xing, Y., Harper, S. Q., Jones, L. and Davidson, B. L. (2008). The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J. Neurosci. 28, 14341-14346.
35. Peters, L. and Meister, G. (2007). Argonaute proteins: mediators of RNA silencing. Mol. Cell 26, 611-623.
36. Pillai, R. S., Bhattacharyya, S. N. and Filipowicz, W. (2007). Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol. 17, 118-126.
37. Qi, H. H., Ongusaha, P. P., Myllyharju, J., Cheng, D., Pakkanen, O., Shi, Y., Lee, S. W. and Peng, J. (2008). Prolyl 4-hydroxylation regulates Argonaute 2 stability. Nature 455, 421-424.
38. Reuter, M., Chuma, S., Tanaka, T., Franz, T., Stark, A. and Pillai, R. S. (2009). Loss of the Mili-interacting Tudor domain-containing protein-1 activates transposons and alters the Mili-associated small RNA profile. Nat. Struct. Mol. Biol. 16, 639-646.
39. Rybak, A., Fuchs, H., Hadian, K., Smirnova, L., Wulczyn, E. A., Michel, G., Nitsch, R., Krappmann, D. and Wulczyn, F. G. (2009). The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2. Nat. Cell Biol. 11, 1411-11220
40. Schwartz, J. C., Younger, S. T., Nguyen, N. B., Hardy, D. B., Monia, B. P., Corey, D. R. and Janowski, B. A. (2008). Antisense transcripts are targets for activating small RNAs. Nat. Struct. Mol. Biol. 15, 842-848.
41. Scott, M. S., Avolio, F., Ono, M., Lamond, A. I. and Barton, G. J. (2009). Human miRNA precursors with box H/ACA snoRNA features. PLoS Comput. Biol. 5, e1000507.
42. Siomi, H. and Siomi, M. C. (2009). On the road to reading the RNA-interference code. Nature 457, 396-404.
43. Steiner, F. A., Okihara, K. L., Hoogstrate, S. W., Sijen, T. and Ketting, R. F. (2009). RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans. Nat. Struct. Mol. Biol. 16, 207-211.
44. Taft, R. J., Glazov, E. A., Lassmann, T., Hayashizaki, Y., Carninci, P. and Mattick, J. S. (2009). Small RNAs derived from snoRNAs. RNA 15, 1233-1240.
45. Tam, O. H., Aravin, A. A., Stein, P., Girard, A., Murchison, E. P., Cheloufi, S., Hodges, E., Anger, M., Sachidanandam, R., Schultz, R. M. et al. (2008). Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature 453, 534-538.
46. Till, S., Lejeune, E., Thermann, R., Bortfeld, M., Hothorn, M., Enderle, D., Heinrich, C., Hentze, M. W. and Ladurner, A. G. (2007). A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain. Nat. Struct. Mol. Biol. 14, 897-903.
47. Tolia, N. H. and Joshua-Tor, L. (2007). Slicer and the argonautes. Nat. Chem. Biol. 3, 36-43.
48. Vagin, V. V., Wohlschlegel, J., Qu, J., Jonsson, Z., Huang, X., Chuma, S., Girard, A., Sachidanandam, R., Hannon, G. J. and Aravin, A. A. (2009). Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev. 23, 1749-1762.
49. Wang, B., Li, S., Qi, H. H., Chowdhury, D., Shi, Y. and Novina, C. D. (2009). Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat. Struct. Mol. Biol. 16, 1259-1266.
50. Wang, Y., Juranek, S., Li, H., Sheng, G., Tuschl, T. and Patel, D. J. (2008a). Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature 456, 921-926.
51. Wang, Y., Sheng, G., Juranek, S., Tuschl, T. and Patel, D. J. (2008b). Structure of the guide-strand-containing argonaute silencing complex. Nature 456, 209-213.
52. Wang, Y., Juranek, S., Li, H., Sheng, G., Wardle, G. S., Tuschl, T. and Patel, D. J. (2009). Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature 461, 754-761.
53. Watanabe, T., Totoki, Y., Toyoda, A., Kaneda, M., Kuramochi-Miyagawa, S., Obata, Y., Chiba, H., Kohara, Y., Kono, T., Nakano, T. et al. (2008). Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature 453, 539-543.
54. Weinmann, L., Hock, J., Ivacevic, T., Ohrt, T., Mutze, J., Schwille, P., Kremmer, E., Benes, V., Urlaub, H. and Meister, G. (2009). Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell 136, 496-507.
55. Wu, L. and Belasco, J. G. (2005). Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Mol. Cell. Biol. 25, 9198-9208.
56. Zekri, L., Huntzinger, E., Heimstadt, S. and Izaurralde, E. (2009). The silencing domain of GW182 interacts with PABPC1 to promote translational repression and degradation of microRNA targets and is required for target release. Mol. Cell. Biol. 29, 6220-6231.
57. Zeng, Y., Sankala, H., Zhang, X. and Graves, P. (2008). Phosphorylation of Argonaute2 at serine 387 facilitates its localization to processing bodies. Biochem. J. 413, 429-436.