Multinucleation regulated by the Akt/PTEN signaling pathway is a survival strategy for HepG2 cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 755, Issue 2, 2013, Pages 135-140

  Mukherjee, Ananda ^a   Misra, Sandip ^a   Howlett, Niall G ^b   Karmakar, Parimal ^a  

^a JADAVPUR UNIVERSITY   (India)

^b UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Akt; Chang Liver; Cytokinesis block micronucleus assay; HepG2; Multinucleation; PTEN

Indexed keywords

ALPHA FETOPROTEIN; ETOPOSIDE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ARTICLE; CANCER CELL; CATALYSIS; CELL ACTIVITY; CELL STRAIN HEPG2; CELL SURVIVAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINESIS; CYTOTOXICITY; DNA DAMAGE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LIVER; LIVER CELL; LIVER CELL CARCINOMA; MULTINUCLEATION; NUCLEAR DIVISION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

AKT; CHANG LIVER; CYTOKINESIS-BLOCK MICRONUCLEUS ASSAY; HEPG2; MULTINUCLEATION; PTEN;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL FUSION; CELL SURVIVAL; DNA DAMAGE; DNA REPAIR; DNA, NEOPLASM; DRUG RESISTANCE, NEOPLASM; ETOPOSIDE; GIANT CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; MICRONUCLEUS TESTS; NEOPLASM PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TOPOISOMERASE II INHIBITORS;

EID: 84881025663     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.06.009     Document Type: Article

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