Attenuation of PTEN perturbs genomic stability via activation of Akt and down-regulation of Rad51 in human embryonic kidney cells

Molecular Carcinogenesis

Volumn 52, Issue 8, 2013, Pages 611-618

  Mukherjee, Ananda ^a   Karmakar, Parimal ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

H2AX; Akt; API 59CJ OMe; Genomic instability; PTEN; Rad51

Indexed keywords

ETOPOSIDE; GAMMA HISTONE H2AX; HISTONE H2AX; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RAD51 PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL STRAIN HEK293; CELL SURVIVAL; CONTROLLED STUDY; DNA REPAIR; DOWN REGULATION; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; GENE FUNCTION; GENE SILENCING; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN FUNCTION; UPREGULATION;

ΓH2AX; AKT; API-59CJ-OME; GENOMIC INSTABILITY; PTEN; RAD51;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CHROMOSOME ABERRATIONS; DRUG RESISTANCE, NEOPLASM; ENZYME ACTIVATION; ETOPOSIDE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; GENOMIC INSTABILITY; HEK293 CELLS; HISTONES; HUMANS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RAD51 RECOMBINASE;

EID: 84880327883     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.21903     Document Type: Article

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