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Volumn 7, Issue 17, 2008, Pages 2621-2625

PI3-K and GSK-3: Akt-ing together with microtubules

Author keywords

Akt; Centrosome; GSK 3; Microtubule; Mitosis; PI3 kinase

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 50849127509     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.7.17.6514     Document Type: Review
Times cited : (73)

References (47)
  • 3
    • 0029810181 scopus 로고    scopus 로고
    • Kohn AD, Takeuchi F, Roth RA. Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation. J Biol Chem 1996; 271:21920-6.
    • Kohn AD, Takeuchi F, Roth RA. Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylation. J Biol Chem 1996; 271:21920-6.
  • 5
    • 0034704141 scopus 로고    scopus 로고
    • Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1
    • Wick MJ, Dong LQ, Riojas RA, Ramos FJ, Liu F. Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1. J Biol Chem 2000; 275:40400-6.
    • (2000) J Biol Chem , vol.275 , pp. 40400-40406
    • Wick, M.J.1    Dong, L.Q.2    Riojas, R.A.3    Ramos, F.J.4    Liu, F.5
  • 6
    • 15044363028 scopus 로고    scopus 로고
    • Recent advances in the protein kinase B signaling pathway
    • Woodgett JR. Recent advances in the protein kinase B signaling pathway. Curr Opin Cell Biol 2005; 17:150-7.
    • (2005) Curr Opin Cell Biol , vol.17 , pp. 150-157
    • Woodgett, J.R.1
  • 7
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995; 378:785-9.
    • (1995) Nature , vol.378 , pp. 785-789
    • Cross, D.A.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 8
    • 0032748099 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones
    • Goold RG, Owen R, Gordon-Weeks PR. Glycogen synthase kinase 3beta phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones. J Cell Sci 1999; 112:3373-84.
    • (1999) J Cell Sci , vol.112 , pp. 3373-3384
    • Goold, R.G.1    Owen, R.2    Gordon-Weeks, P.R.3
  • 9
    • 0026487365 scopus 로고
    • Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase
    • Hanger DP, Hughes K, Woodgett JR, Brion JP, Anderton BH. Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase. Neurosci Lett 1992; 147:58-62.
    • (1992) Neurosci Lett , vol.147 , pp. 58-62
    • Hanger, D.P.1    Hughes, K.2    Woodgett, J.R.3    Brion, J.P.4    Anderton, B.H.5
  • 11
    • 0029664368 scopus 로고    scopus 로고
    • Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly
    • Rubinfeld B, Albert I, Porfiri E, Fiol C, Munemitsu S, Polakis P. Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly. Science 1996; 272:1023-6.
    • (1996) Science , vol.272 , pp. 1023-1026
    • Rubinfeld, B.1    Albert, I.2    Porfiri, E.3    Fiol, C.4    Munemitsu, S.5    Polakis, P.6
  • 12
    • 0035176077 scopus 로고    scopus 로고
    • Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3beta phosphorylation
    • Zumbrunn J, Kinoshita K, Hyman AA, Nathke IS. Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3beta phosphorylation. Curr Biol 2001; 11:44-9.
    • (2001) Curr Biol , vol.11 , pp. 44-49
    • Zumbrunn, J.1    Kinoshita, K.2    Hyman, A.A.3    Nathke, I.S.4
  • 14
    • 33845683023 scopus 로고    scopus 로고
    • The Schizosaccharomyces pombe EB1 homolog Mal3p binds and stabilizes the microtubule lattice seam
    • Sandblad L, Busch KE, Tittmann P, Gross H, Brunner D, Hoenger A. The Schizosaccharomyces pombe EB1 homolog Mal3p binds and stabilizes the microtubule lattice seam. Cell 2006; 127:1415-24.
    • (2006) Cell , vol.127 , pp. 1415-1424
    • Sandblad, L.1    Busch, K.E.2    Tittmann, P.3    Gross, H.4    Brunner, D.5    Hoenger, A.6
  • 18
    • 0031779645 scopus 로고    scopus 로고
    • Phosphorylation of stathmin modulates its function as a microtubule depolymerizing factor
    • Moreno FJ, Avila J. Phosphorylation of stathmin modulates its function as a microtubule depolymerizing factor. Mol Cell Biochem 1998; 183:201-9.
    • (1998) Mol Cell Biochem , vol.183 , pp. 201-209
    • Moreno, F.J.1    Avila, J.2
  • 20
    • 3342936441 scopus 로고    scopus 로고
    • Phosphorylation of tau at THR212 and SER214 in human neuronal and glial cultures: The role of AKT
    • Kyoung Pyo H, Lovati E, Pasinetti GM, Ksiezak-Reding H. Phosphorylation of tau at THR212 and SER214 in human neuronal and glial cultures: the role of AKT. Neuroscience 2004; 127:649-58.
    • (2004) Neuroscience , vol.127 , pp. 649-658
    • Kyoung Pyo, H.1    Lovati, E.2    Pasinetti, G.M.3    Ksiezak-Reding, H.4
  • 21
    • 33947142869 scopus 로고    scopus 로고
    • Microtubule-induced cortical cell polarity
    • Siegrist SE, Doe CQ. Microtubule-induced cortical cell polarity. Genes Dev 2007; 21:483-96.
    • (2007) Genes Dev , vol.21 , pp. 483-496
    • Siegrist, S.E.1    Doe, C.Q.2
  • 22
    • 33947620706 scopus 로고    scopus 로고
    • The PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts
    • Onishi K, Higuchi M, Asakura T, Masuyama N, Gotoh Y. The PI3K-Akt pathway promotes microtubule stabilization in migrating fibroblasts. Genes Cells 2007; 12:535-46.
    • (2007) Genes Cells , vol.12 , pp. 535-546
    • Onishi, K.1    Higuchi, M.2    Asakura, T.3    Masuyama, N.4    Gotoh, Y.5
  • 23
    • 0345169048 scopus 로고    scopus 로고
    • Post-translational modifications regulate microtubule function
    • Westermann S, Weber K. Post-translational modifications regulate microtubule function. Nat Rev Mol Cell Biol 2003; 4:938-47.
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 938-947
    • Westermann, S.1    Weber, K.2
  • 24
    • 24944577909 scopus 로고    scopus 로고
    • Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization
    • Etienne-Manneville S, Manneville JB, Nicholls S, Ferenczi MA, Hall A. Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization. J Cell Biol 2005; 170:895-901.
    • (2005) J Cell Biol , vol.170 , pp. 895-901
    • Etienne-Manneville, S.1    Manneville, J.B.2    Nicholls, S.3    Ferenczi, M.A.4    Hall, A.5
  • 25
    • 0030987826 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein
    • Neufeld KL, White RL. Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein. Proc Natl Acad Sci USA 1997; 94:3034-9.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3034-3039
    • Neufeld, K.L.1    White, R.L.2
  • 26
    • 0037434790 scopus 로고    scopus 로고
    • Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity
    • Etienne-Manneville S, Hall A. Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature 2003; 421:753-6.
    • (2003) Nature , vol.421 , pp. 753-756
    • Etienne-Manneville, S.1    Hall, A.2
  • 28
    • 33745068650 scopus 로고    scopus 로고
    • GSK3beta and PKCzeta function in centrosome localization and process stabilization during Slit-mediated neuronal repolarization
    • Higginbotham H, Tanaka T, Brinkman BC, Gleeson JG. GSK3beta and PKCzeta function in centrosome localization and process stabilization during Slit-mediated neuronal repolarization. Mol Cell Neurosci 2006; 32:118-32.
    • (2006) Mol Cell Neurosci , vol.32 , pp. 118-132
    • Higginbotham, H.1    Tanaka, T.2    Brinkman, B.C.3    Gleeson, J.G.4
  • 29
    • 0033588939 scopus 로고    scopus 로고
    • Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis
    • McCartney BM, Dierick HA, Kirkpatrick C, Moline MM, Baas A, Peifer M, Bejsovec A. Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis. J Cell Biol 1999; 146:1303-18.
    • (1999) J Cell Biol , vol.146 , pp. 1303-1318
    • McCartney, B.M.1    Dierick, H.A.2    Kirkpatrick, C.3    Moline, M.M.4    Baas, A.5    Peifer, M.6    Bejsovec, A.7
  • 31
    • 0141483737 scopus 로고    scopus 로고
    • Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome
    • Yamashita YM, Jones DL, Fuller MT. Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome. Science 2003; 301:1547-50.
    • (2003) Science , vol.301 , pp. 1547-1550
    • Yamashita, Y.M.1    Jones, D.L.2    Fuller, M.T.3
  • 33
    • 39049150477 scopus 로고    scopus 로고
    • Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo
    • Buttrick GJ, Beaumont LM, Leitch J, Yau C, Hughes JR, Wakefield JG. Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo. J Cell Biol 2008; 180:537-48.
    • (2008) J Cell Biol , vol.180 , pp. 537-548
    • Buttrick, G.J.1    Beaumont, L.M.2    Leitch, J.3    Yau, C.4    Hughes, J.R.5    Wakefield, J.G.6
  • 34
    • 0035945614 scopus 로고    scopus 로고
    • Adherens junctions inhibit asymmetric division in the Drosophila epithelium
    • Lu B, Roegiers F, Jan LY, Jan YN. Adherens junctions inhibit asymmetric division in the Drosophila epithelium. Nature 2001; 409:522-5.
    • (2001) Nature , vol.409 , pp. 522-525
    • Lu, B.1    Roegiers, F.2    Jan, L.Y.3    Jan, Y.N.4
  • 35
    • 36448980590 scopus 로고    scopus 로고
    • Toyoshima F, Matsumura S, Morimoto H, Mitsushima M, Nishida E. PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells. Dev Cell 2007; 13:796-811.
    • Toyoshima F, Matsumura S, Morimoto H, Mitsushima M, Nishida E. PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells. Dev Cell 2007; 13:796-811.
  • 36
    • 0037018847 scopus 로고    scopus 로고
    • A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle
    • Shtivelman E, Sussman J, Stokoe D. A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle. Curr Biol 2002; 12:919-24.
    • (2002) Curr Biol , vol.12 , pp. 919-924
    • Shtivelman, E.1    Sussman, J.2    Stokoe, D.3
  • 37
    • 0037442990 scopus 로고    scopus 로고
    • A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment
    • Wakefield JG, Stephens DJ, Tavare JM. A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment. J Cell Sci 2003; 116:637-46.
    • (2003) J Cell Sci , vol.116 , pp. 637-646
    • Wakefield, J.G.1    Stephens, D.J.2    Tavare, J.M.3
  • 38
    • 38349088626 scopus 로고    scopus 로고
    • Protein kinase B (PKB/Akt) is required for the completion of meiosis in mouse oocytes
    • Hoshino Y, Sato E. Protein kinase B (PKB/Akt) is required for the completion of meiosis in mouse oocytes. Dev Biol 2008; 314:215-23.
    • (2008) Dev Biol , vol.314 , pp. 215-223
    • Hoshino, Y.1    Sato, E.2
  • 40
    • 0038385019 scopus 로고    scopus 로고
    • Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics
    • Maiato H, Fairley EA, Rieder CL, Swedlow JR, Sunkel CE, Earnshaw WC. Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics. Cell 2003; 113:891-904.
    • (2003) Cell , vol.113 , pp. 891-904
    • Maiato, H.1    Fairley, E.A.2    Rieder, C.L.3    Swedlow, J.R.4    Sunkel, C.E.5    Earnshaw, W.C.6
  • 41
    • 47949089393 scopus 로고    scopus 로고
    • AIP regulates stability of Aurora-A at early mitotic phase coordinately with GSK-3beta(*)
    • Fumoto K, Lee PC, Saya H, Kikuchi A. AIP regulates stability of Aurora-A at early mitotic phase coordinately with GSK-3beta(*). Oncogene 2008.
    • (2008) Oncogene
    • Fumoto, K.1    Lee, P.C.2    Saya, H.3    Kikuchi, A.4
  • 42
    • 45149086638 scopus 로고    scopus 로고
    • GSK-3beta regulates proper mitotic spindle formation in cooperation with a component of the gamma-tubulin ring complex, GCP5
    • Izumi N, Fumoto K, Izumi S, Kikuchi A. GSK-3beta regulates proper mitotic spindle formation in cooperation with a component of the gamma-tubulin ring complex, GCP5. J Biol Chem 2008; 283:12981-91.
    • (2008) J Biol Chem , vol.283 , pp. 12981-12991
    • Izumi, N.1    Fumoto, K.2    Izumi, S.3    Kikuchi, A.4
  • 43
    • 33646871571 scopus 로고    scopus 로고
    • Shaggy/GSK-3beta kinase localizes to the centrosome and to specialized cytoskeletal structures in Drosophila
    • Bobinnec Y, Morin X, Debec A. Shaggy/GSK-3beta kinase localizes to the centrosome and to specialized cytoskeletal structures in Drosophila. Cell Motil Cytoskeleton 2006; 63:313-20.
    • (2006) Cell Motil Cytoskeleton , vol.63 , pp. 313-320
    • Bobinnec, Y.1    Morin, X.2    Debec, A.3
  • 44
    • 18844366664 scopus 로고    scopus 로고
    • Efficient chromosome capture requires a bias in the 'search-and-capture' process during mitotic-spindle assembly
    • Wollman R, Cytrynbaum EN, Jones JT, Meyer T, Scholey JM, Mogilner A. Efficient chromosome capture requires a bias in the 'search-and-capture' process during mitotic-spindle assembly. Curr Biol 2005; 15:828-32.
    • (2005) Curr Biol , vol.15 , pp. 828-832
    • Wollman, R.1    Cytrynbaum, E.N.2    Jones, J.T.3    Meyer, T.4    Scholey, J.M.5    Mogilner, A.6
  • 45
    • 25444485717 scopus 로고    scopus 로고
    • Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules
    • Barros TP, Kinoshita K, Hyman AA, Raff JW. Aurora A activates D-TACC-Msps complexes exclusively at centrosomes to stabilize centrosomal microtubules. J Cell Biol 2005; 170:1039-46.
    • (2005) J Cell Biol , vol.170 , pp. 1039-1046
    • Barros, T.P.1    Kinoshita, K.2    Hyman, A.A.3    Raff, J.W.4
  • 46
    • 45749115811 scopus 로고    scopus 로고
    • Fuller BG, Lampson MA, Foley EA, Rosasco-Nitcher S, Le KV, Tobelmann P, Brautigan DL, Stukenberg PT, Kapoor TM. Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. Nature 2008.
    • Fuller BG, Lampson MA, Foley EA, Rosasco-Nitcher S, Le KV, Tobelmann P, Brautigan DL, Stukenberg PT, Kapoor TM. Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. Nature 2008.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.