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Volumn 15, Issue 14, 2009, Pages 4538-4545

Activation of phosphatidylinositol-3′-kinase/AKT signaling is essential in hepatoblastoma survival

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; GLYCOGEN SYNTHASE KINASE 3BETA; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

EID: 68049113683     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-08-2878     Document Type: Article
Times cited : (66)

References (33)
  • 1
    • 33747112664 scopus 로고    scopus 로고
    • Liver cancer in European children: Incidence and survival, 1978-1997. Report from the Automated Childhood Cancer Information System project
    • Stiller CA, Pritchard J, Steliarova-Foucher E. Liver cancer in European children: incidence and survival, 1978-1997. Report from the Automated Childhood Cancer Information System project. Eur J Cancer 2006;42:2115-2123
    • (2006) Eur J Cancer , vol.42 , pp. 2115-2123
    • Stiller, C.A.1    Pritchard, J.2    Steliarova-Foucher, E.3
  • 3
    • 0029122489 scopus 로고
    • Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: Uncoupling of IGF2 and H19 imprinting
    • Li X, Adam G, Cui H, Sandstedt B, Ohlsson R, Ekstrom TJ. Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: uncoupling of IGF2 and H19 imprinting. Oncogene 1995;11:221-229
    • (1995) Oncogene , vol.11 , pp. 221-229
    • Li, X.1    Adam, G.2    Cui, H.3    Sandstedt, B.4    Ohlsson, R.5    Ekstrom, T.J.6
  • 4
    • 0033815532 scopus 로고    scopus 로고
    • P57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19
    • Hartmann W, Waha A, Koch A, et al. p57(KIP2) is not mutated in hepatoblastoma but shows increased transcriptional activity in a comparative analysis of the three imprinted genes p57(KIP2), IGF2, and H19. Am J Pathol 2000;157:1393-1403 (Pubitemid 30757959)
    • (2000) American Journal of Pathology , vol.157 , Issue.4 , pp. 1393-1403
    • Hartmann, W.1    Waha, A.2    Koch, A.3    Goodyer, C.G.4    Albrecht, S.5    Von Schweinitz, D.6    Pietsch, T.7
  • 5
    • 0029587224 scopus 로고
    • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
    • DOI 10.1038/378785a0
    • Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 1995;378:785-789 (Pubitemid 26004411)
    • (1995) Nature , vol.378 , Issue.6559 , pp. 785-789
    • Cross, D.A.E.1    Alessi, D.R.2    Cohen, P.3    Andjelkovich, M.4    Hemmings, B.A.5
  • 6
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase-AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer 2002;2:489-501. (Pubitemid 37328931)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.7 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 7
    • 13844273087 scopus 로고    scopus 로고
    • PI3K-Akt pathway: Its functions and alterations in human cancer
    • DOI 10.1023/B:APPT.0000045801.15585.dd
    • Osaki M, Oshimura M, Ito H. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis 2004;9:667-676 (Pubitemid 40941196)
    • (2004) Apoptosis , vol.9 , Issue.6 , pp. 667-676
    • Osaki, M.1    Oshimura, M.2    Ito, H.3
  • 8
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization
    • Diehl JA, Cheng M, Roussel MF, Sherr CJ. Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 1998;12:3499-3511 (Pubitemid 28553242)
    • (1998) Genes and Development , vol.12 , Issue.22 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3    Sherr, C.J.4
  • 9
    • 2342559981 scopus 로고    scopus 로고
    • The TOR pathway: A target for cancer therapy
    • Bjornsti MA, Houghton PJ. The TOR pathway: a target for cancer therapy. Nat Rev Cancer 2004;4:335-348 (Pubitemid 38579480)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.5 , pp. 335-348
    • Bjornsti, M.-A.1    Houghton, P.J.2
  • 11
    • 2342618936 scopus 로고    scopus 로고
    • Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
    • Liang J, Slingerland JM. Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2003;2:339-345
    • (2003) Cell Cycle , vol.2 , pp. 339-345
    • Liang, J.1    Slingerland, J.M.2
  • 12
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. Cancer cell cycles. Science 1996;274:1672-1677
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 14
    • 3442878125 scopus 로고    scopus 로고
    • Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas
    • Broderick DK, Di C, Parrett TJ, et al. Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas. Cancer Res 2004;64:5048-5050
    • (2004) Cancer Res , vol.64 , pp. 5048-5050
    • Broderick, D.K.1    Di, C.2    Parrett, T.J.3
  • 15
    • 0017260918 scopus 로고
    • Establishment of a cell line and its clonal sublines from a patient with hepatoblastoma
    • Doi L. Establishment of a cell line and its clonal sublines from a patient with hepatoblastoma. Gann 1976;67:1-10.
    • (1976) Gann , vol.67 , pp. 1-10
    • Doi, L.1
  • 21
    • 4344708374 scopus 로고    scopus 로고
    • Selective usage of D-type cyclins by Ewing's tumors and rhabdomyosarcomas
    • DOI 10.1158/0008-5472.CAN-03-2594
    • Zhang J, Hu S, Schofield DE, Sorensen PH, Triche TJ. Selective usage of D-Type cyclins by Ewing's tumors and rhabdomyosarcomas. Cancer Res 2004;64:6026-6034 (Pubitemid 39129400)
    • (2004) Cancer Research , vol.64 , Issue.17 , pp. 6026-6034
    • Zhang, J.1    Hu, S.2    Schofield, D.E.3    Sorensen, P.H.B.4    Triche, T.J.5
  • 23
    • 0029948828 scopus 로고    scopus 로고
    • Involvement of IGF-II in human cancer
    • Toretsky JA, Helman LJ. Involvement of IGF-II in human cancer. J Endocrinol 1996;149:367-372
    • (1996) J Endocrinol , vol.149 , pp. 367-372
    • Toretsky, J.A.1    Helman, L.J.2
  • 24
    • 33751001327 scopus 로고    scopus 로고
    • Signaling pathway of insulin-like growth factor-II as a target of molecular therapy for hepatoblastoma
    • Tomizawa M, Saisho H. Signaling pathway of insulin-like growth factor-II as a target of molecular therapy for hepatoblastoma. World J Gastroenterol 2006;12:6531-6535 (Pubitemid 44742590)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.40 , pp. 6531-6535
    • Tomizawa, M.1    Saisho, H.2
  • 25
    • 28844448182 scopus 로고    scopus 로고
    • Oncogenic PI3K deregulates transcription and translation
    • DOI 10.1038/nrc1753
    • Bader AG, Kang S, Zhao L, Vogt PK. Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer 2005;5:921-929 (Pubitemid 41766781)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.12 , pp. 921-929
    • Bader, A.G.1    Kang, S.2    Zhao, L.3    Vogt, P.K.4
  • 28
    • 0033556426 scopus 로고    scopus 로고
    • Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene
    • Koch A, Denkhaus D, Albrecht S, Leuschner I, von Schweinitz D, Pietsch T. Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. Cancer Res 1999;59:269-273 (Pubitemid 29048850)
    • (1999) Cancer Research , vol.59 , Issue.2 , pp. 269-273
    • Koch, A.1    Denkhaus, D.2    Albrecht, S.3    Leuschner, I.4    Von Schweinitz, D.5    Pietsch, T.6
  • 30
    • 0033913603 scopus 로고    scopus 로고
    • Control of β-catenin signaling in tumor development
    • Behrens J. Control of β-catenin signaling in tumor development. Ann N Y Acad Sci 2000;910:21-33; discussion 33-125 (Pubitemid 30462055)
    • (2000) Annals of the New York Academy of Sciences , vol.910 , pp. 21-35
    • Behrens, J.1
  • 31
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell- Intrinsic death machinery
    • DOI 10.1016/S0092-8674(00)80405-5
    • Datta SR, Dudek H, Tao X, et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 1997;91:231-241 (Pubitemid 27456390)
    • (1997) Cell , vol.91 , Issue.2 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Xu, T.3    Masters, S.4    Haian, F.5    Gotoh, Y.6    Greenberg, M.E.7
  • 32
    • 33644855216 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
    • DOI 10.1016/j.molcel.2006.02.009, PII S1097276506001110
    • Maurer U, Charvet C, Wagman AS, Dejardin E, Green DR. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell 2006;21:749-760 (Pubitemid 43376126)
    • (2006) Molecular Cell , vol.21 , Issue.6 , pp. 749-760
    • Maurer, U.1    Charvet, C.2    Wagman, A.S.3    Dejardin, E.4    Green, D.R.5
  • 33
    • 51049112961 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- And drug-induced apoptosis
    • Opel D, Westhoff MA, Bender A, Braun V, Debatin KM, Fulda S. Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis. Cancer Res 2008;68:6271-6280
    • (2008) Cancer Res , vol.68 , pp. 6271-6280
    • Opel, D.1    Westhoff, M.A.2    Bender, A.3    Braun, V.4    Debatin, K.M.5    Fulda, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.