The strength of genetic interactions scales weakly with mutational effects

Genome Biology

Volumn 14, Issue 7, 2013, Pages

  Velenich, Andrea ^a   Gore, Jeff ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Epistasis; Evolution; Fitness landscapes; Genetic interactions; Yeast

Indexed keywords

ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; EPISTASIS; EVOLUTION; GENE INTERACTION; GENE MUTATION; HIGH THROUGHPUT SCREENING; KNOCKOUT GENE; MATHEMATICAL MODEL; MATHEMATICAL PHENOMENA; MUTANT; NONHUMAN; PREDICTION; SACCHAROMYCES CEREVISIAE; STATISTICAL ANALYSIS; THEORETICAL MODEL; YEAST; DYNAMICS; FITNESS; GENETIC CONSERVATION; GEOMETRY; GROWTH RATE; LANDSCAPE; MATHEMATICAL ANALYSIS; MUTATIONAL ANALYSIS; NOISE; PROBABILITY; QUANTITATIVE TRAIT; SPECIES DIFFERENTIATION; STRENGTH; BIOLOGICAL MODEL; GENE INACTIVATION; GENETICS; MUTATION; POINT MUTATION;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

BIOLOGICAL EVOLUTION; EPISTASIS, GENETIC; GENE KNOCKOUT TECHNIQUES; MODELS, GENETIC; MUTATION; POINT MUTATION; SACCHAROMYCES CEREVISIAE;

EID: 84880952364     PISSN: None     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2013-14-7-r76     Document Type: Article

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