Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence

Development (Cambridge)

Volumn 140, Issue 16, 2013, Pages 3403-3412

  Laux, Derek W ^a   Young, Sarah ^a   Donovan, James P ^a   Mansfield, Corrine J ^a   Upton, Paul D ^b   Roman, Beth L ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Alk1 Acvrl1; Arteriovenous malformation; Bmp10; Flow response; Hereditary hemorrhagic telangiectasia; Zebrafish

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 10; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTERY BLOOD FLOW; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

ALK1/ACVRL1; ARTERIOVENOUS MALFORMATION; BMP10; FLOW RESPONSE; HEREDITARY HEMORRHAGIC TELANGIECTASIA; ZEBRAFISH;

ACTIVIN RECEPTORS; ANIMALS; ARTERIOVENOUS MALFORMATIONS; BONE MORPHOGENETIC PROTEINS; CAROTID ARTERIES; CELL COUNT; EMBRYO, NONMAMMALIAN; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE KNOCKDOWN TECHNIQUES; MYOCARDIUM; PHOSPHORYLATION; PROTEIN TRANSPORT; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84880943217     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.095307     Document Type: Article

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