BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Park, John E S ^a   Shao, Dongmin ^a   Upton, Paul D ^b   deSouza, Patricia ^a   Adcock, Ian M ^c   Davies, Rachel J ^b   Morrell, Nicholas W ^b   Griffiths, Mark J D ^a   Wort, Stephen J ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR LIKE KINASE 1; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN 9; ENDOTHELIN 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD1 PROTEIN; SMAD4 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; ENDOTHELIN B RECEPTOR; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; OLIGOPEPTIDE; PIPERIDINE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; LUNG ARTERY; MIGRATION INHIBITION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION REGULATION; WESTERN BLOTTING; ANGIOGENESIS; BIOSYNTHESIS; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; PULMONARY ARTERY;

CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DOWN-REGULATION; ENDOTHELIAL CELLS; ENDOTHELIN-1; GROWTH DIFFERENTIATION FACTOR 2; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; OLIGOPEPTIDES; PIPERIDINES; PULMONARY ARTERY; RECEPTOR, ENDOTHELIN B; SMAD1 PROTEIN;

EID: 84863038822     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030075     Document Type: Article

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