Impaired surface expression and conductance of the KCNQ4 channel lead to sensorineural hearing loss

Journal of Cellular and Molecular Medicine

Volumn 17, Issue 7, 2013, Pages 889-900

  Gao, Yanhong ^a   Yechikov, Sergey ^a   Vázquez, Ana E ^a   Chen, Dongyang ^a   Nie, Liping ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Hearing loss; KCNQ4; Molecular chaperone; Mutations; Potassium channel; Surface expression; Trafficking

Indexed keywords

CHAPERONE; HEAT SHOCK PROTEIN 90; KCNQ4 PROTEIN, HUMAN; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNQ;

ARTICLE; CELL MEMBRANE; CELL STRAIN HEK293; DOMINANT GENE; ELECTROPHYSIOLOGY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; HAIR CELL; HEARING IMPAIRMENT; HUMAN; KCNQ4; MEMBRANE POTENTIAL; METABOLISM; MUTATION; MUTATIONS; PATHOPHYSIOLOGY; PERCEPTION DEAFNESS; SURFACE EXPRESSION; SURFACE PROPERTY; TRAFFICKING;

HEARING LOSS; KCNQ4; MOLECULAR CHAPERONE; MUTATIONS; POTASSIUM CHANNEL; SURFACE EXPRESSION; TRAFFICKING;

CELL MEMBRANE; ELECTROPHYSIOLOGY; GENE EXPRESSION REGULATION; GENES, DOMINANT; HAIR CELLS, AUDITORY; HEARING LOSS, SENSORINEURAL; HEK293 CELLS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; KCNQ POTASSIUM CHANNELS; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; MOLECULAR CHAPERONES; MUTATION; SURFACE PROPERTIES;

EID: 84880822048     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.12080     Document Type: Article

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