In silico modeling of the pore region of a KCNQ4 missense mutant from a patient with hearing loss

BMC Research Notes

Volumn 5, Issue , 2012, Pages

  Namba, Kazunori ^a   Mutai, Hideki ^a   Kaneko, Hiroki ^b   Hashimoto, Sho ^c   Matsunaga, Tatsuo ^a  

^a NATIONAL HOSPITAL ORGANIZATION TOKYO MEDICAL CENTER   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c SENDAI CITY MEDICAL CENTER   (Japan)

Author keywords

Channel; Deafness; Electrostatic; Hearing loss; Molecular Modeling; Mutation; Potassium; Structure

Indexed keywords

KCNQ4 PROTEIN, HUMAN; POTASSIUM CHANNEL KCNQ;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; AUDIOMETRY; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; MISSENSE MUTATION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PERCEPTION DEAFNESS; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; STATIC ELECTRICITY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AUDIOMETRY; BASE SEQUENCE; DNA MUTATIONAL ANALYSIS; HEARING LOSS, SENSORINEURAL; HUMANS; KCNQ POTASSIUM CHANNELS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; STATIC ELECTRICITY;

EID: 84858125876     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/1756-0500-5-145     Document Type: Article

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