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Volumn 71, Issue , 2013, Pages 59-93

Structure and Function of Endoplasmic Reticulum STIM Calcium Sensors

Author keywords

Calcium release activated calcium; Nuclear magnetic resonance spectroscopy; Orai1; STIM1; STIM2; Store operated calcium entry; Stromal interaction molecule; X ray crystallography

Indexed keywords


EID: 84880754162     PISSN: 10635823     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-407870-3.00003-2     Document Type: Chapter
Times cited : (25)

References (113)
  • 3
    • 0036877142 scopus 로고    scopus 로고
    • The endoplasmic reticulum: A multifunctional signaling organelle
    • Berridge M.J. The endoplasmic reticulum: A multifunctional signaling organelle. Cell Calcium 2002, 32(5-6):235-249.
    • (2002) Cell Calcium , vol.32 , Issue.5-6 , pp. 235-249
    • Berridge, M.J.1
  • 11
    • 40849144052 scopus 로고    scopus 로고
    • Molecular evolution and functional divergence of the Ca(2+) sensor protein in store-operated Ca(2+) entry: Stromal interaction molecule
    • Cai X. Molecular evolution and functional divergence of the Ca(2+) sensor protein in store-operated Ca(2+) entry: Stromal interaction molecule. PLoS One 2007, 2(7):e609.
    • (2007) PLoS One , vol.2 , Issue.7
    • Cai, X.1
  • 12
    • 34247193635 scopus 로고    scopus 로고
    • Molecular evolution and structural analysis of the Ca(2+) release-activated Ca(2+) channel subunit, Orai
    • Cai X. Molecular evolution and structural analysis of the Ca(2+) release-activated Ca(2+) channel subunit, Orai. Journal of Molecular Biology 2007, 368(5):1284-1291.
    • (2007) Journal of Molecular Biology , vol.368 , Issue.5 , pp. 1284-1291
    • Cai, X.1
  • 13
    • 79961156737 scopus 로고    scopus 로고
    • Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)P(2) between distinct membrane pools
    • Calloway N., Owens T., Corwith K., Rodgers W., Holowka D., Baird B. Stimulated association of STIM1 and Orai1 is regulated by the balance of PtdIns(4,5)P(2) between distinct membrane pools. Journal of Cell Science 2011, 124(Pt. 15):2602-2610.
    • (2011) Journal of Cell Science , vol.124 , Issue.PART 15 , pp. 2602-2610
    • Calloway, N.1    Owens, T.2    Corwith, K.3    Rodgers, W.4    Holowka, D.5    Baird, B.6
  • 15
    • 77952919805 scopus 로고    scopus 로고
    • Essential role for the CRAC activation domain in store-dependent oligomerization of STIM1
    • Covington E.D., Wu M.M., Lewis R.S. Essential role for the CRAC activation domain in store-dependent oligomerization of STIM1. Molecular Biology of the Cell 2010, 21(11):1897-1907.
    • (2010) Molecular Biology of the Cell , vol.21 , Issue.11 , pp. 1897-1907
    • Covington, E.D.1    Wu, M.M.2    Lewis, R.S.3
  • 17
    • 34347342283 scopus 로고    scopus 로고
    • Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels
    • DeHaven W.I., Smyth J.T., Boyles R.R., Putney J.W. Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels. The Journal of Biological Chemistry 2007, 282(24):17548-17556.
    • (2007) The Journal of Biological Chemistry , vol.282 , Issue.24 , pp. 17548-17556
    • DeHaven, W.I.1    Smyth, J.T.2    Boyles, R.R.3    Putney, J.W.4
  • 19
    • 34547559704 scopus 로고    scopus 로고
    • PDB2PQR: Expanding and upgrading automated preparation of biomolecular structures for molecular simulations
    • Web Server issue
    • Dolinsky T.J., Czodrowski P., Li H., Nielsen J.E., Jensen J.H., Klebe G., et al. PDB2PQR: Expanding and upgrading automated preparation of biomolecular structures for molecular simulations. Nucleic Acids Research 2007, 35(Web Server issue):W522-W525.
    • (2007) Nucleic Acids Research , vol.35
    • Dolinsky, T.J.1    Czodrowski, P.2    Li, H.3    Nielsen, J.E.4    Jensen, J.H.5    Klebe, G.6
  • 21
    • 78649683967 scopus 로고    scopus 로고
    • Down-regulation of Orai3 arrests cell-cycle progression and induces apoptosis in breast cancer cells but not in normal breast epithelial cells
    • Faouzi M., Hague F., Potier M., Ahidouch A., Sevestre H., Ouadid-Ahidouch H. Down-regulation of Orai3 arrests cell-cycle progression and induces apoptosis in breast cancer cells but not in normal breast epithelial cells. Journal of Cellular Physiology 2011, 226(2):542-551.
    • (2011) Journal of Cellular Physiology , vol.226 , Issue.2 , pp. 542-551
    • Faouzi, M.1    Hague, F.2    Potier, M.3    Ahidouch, A.4    Sevestre, H.5    Ouadid-Ahidouch, H.6
  • 22
    • 84872463873 scopus 로고    scopus 로고
    • ORAI3 silencing alters cell proliferation and cell cycle progression via c-myc pathway in breast cancer cells
    • Faouzi M., Kischel P., Hague F., Ahidouch A., Benzerdjeb N., Sevestre H., et al. ORAI3 silencing alters cell proliferation and cell cycle progression via c-myc pathway in breast cancer cells. Biochimica et Biophysica Acta 2013, 1833(3):752-760.
    • (2013) Biochimica et Biophysica Acta , vol.1833 , Issue.3 , pp. 752-760
    • Faouzi, M.1    Kischel, P.2    Hague, F.3    Ahidouch, A.4    Benzerdjeb, N.5    Sevestre, H.6
  • 23
    • 34548233165 scopus 로고    scopus 로고
    • Calcium signalling in lymphocyte activation and disease
    • Feske S. Calcium signalling in lymphocyte activation and disease. Nature Reviews Immunology 2007, 7(9):690-702.
    • (2007) Nature Reviews Immunology , vol.7 , Issue.9 , pp. 690-702
    • Feske, S.1
  • 24
    • 82555165264 scopus 로고    scopus 로고
    • Immunodeficiency due to defects in store-operated calcium entry
    • Feske S. Immunodeficiency due to defects in store-operated calcium entry. Annals of the New York Academy of Sciences 2012, 1238:74-90.
    • (2012) Annals of the New York Academy of Sciences , vol.1238 , pp. 74-90
    • Feske, S.1
  • 25
    • 33646576875 scopus 로고    scopus 로고
    • A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
    • Feske S., Gwack Y., Prakriya M., Srikanth S., Puppel S.H., Tanasa B., et al. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. Nature 2006, 441(7090):179-185.
    • (2006) Nature , vol.441 , Issue.7090 , pp. 179-185
    • Feske, S.1    Gwack, Y.2    Prakriya, M.3    Srikanth, S.4    Puppel, S.H.5    Tanasa, B.6
  • 26
    • 84862861740 scopus 로고    scopus 로고
    • Ion channels and transporters in lymphocyte function and immunity
    • Feske S., Skolnik E.Y., Prakriya M. Ion channels and transporters in lymphocyte function and immunity. Nature Reviews. Immunology 2012, 12(7):532-547.
    • (2012) Nature Reviews. Immunology , vol.12 , Issue.7 , pp. 532-547
    • Feske, S.1    Skolnik, E.Y.2    Prakriya, M.3
  • 27
    • 69249152563 scopus 로고    scopus 로고
    • Molecular determinants of the coupling between STIM1 and Orai channels: Differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant
    • Frischauf I., Muik M., Derler I., Bergsmann J., Fahrner M., Schindl R., et al. Molecular determinants of the coupling between STIM1 and Orai channels: Differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant. The Journal of Biological Chemistry 2009, 284(32):21696-21706.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.32 , pp. 21696-21706
    • Frischauf, I.1    Muik, M.2    Derler, I.3    Bergsmann, J.4    Fahrner, M.5    Schindl, R.6
  • 29
    • 84856569091 scopus 로고    scopus 로고
    • Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency
    • Fuchs S., Rensing-Ehl A., Speckmann C., Bengsch B., Schmitt-Graeff A., Bondzio I., et al. Antiviral and regulatory T cell immunity in a patient with stromal interaction molecule 1 deficiency. Journal of Immunology 2012, 188(3):1523-1533.
    • (2012) Journal of Immunology , vol.188 , Issue.3 , pp. 1523-1533
    • Fuchs, S.1    Rensing-Ehl, A.2    Speckmann, C.3    Bengsch, B.4    Schmitt-Graeff, A.5    Bondzio, I.6
  • 30
    • 58149127822 scopus 로고    scopus 로고
    • Mechanism of different spatial distributions of Caenorhabditis elegans and human STIM1 at resting state
    • Gao S., Fan Y., Chen L., Lu J., Xu T., Xu P. Mechanism of different spatial distributions of Caenorhabditis elegans and human STIM1 at resting state. Cell Calcium 2009, 45(1):77-88.
    • (2009) Cell Calcium , vol.45 , Issue.1 , pp. 77-88
    • Gao, S.1    Fan, Y.2    Chen, L.3    Lu, J.4    Xu, T.5    Xu, P.6
  • 32
    • 79955542225 scopus 로고    scopus 로고
    • A cytosolic STIM2 preprotein created by signal peptide inefficiency activates ORAI1 in a store-independent manner
    • Graham S.J., Dziadek M.A., Johnstone L.S. A cytosolic STIM2 preprotein created by signal peptide inefficiency activates ORAI1 in a store-independent manner. The Journal of Biological Chemistry 2011, 286(18):16174-16185.
    • (2011) The Journal of Biological Chemistry , vol.286 , Issue.18 , pp. 16174-16185
    • Graham, S.J.1    Dziadek, M.A.2    Johnstone, L.S.3
  • 34
    • 0141483523 scopus 로고    scopus 로고
    • Transcriptional regulation by calcium, calcineurin, and NFAT
    • Hogan P.G., Chen L., Nardone J., Rao A. Transcriptional regulation by calcium, calcineurin, and NFAT. Genes & Development 2003, 17(18):2205-2232.
    • (2003) Genes & Development , vol.17 , Issue.18 , pp. 2205-2232
    • Hogan, P.G.1    Chen, L.2    Nardone, J.3    Rao, A.4
  • 36
    • 84870655957 scopus 로고    scopus 로고
    • Crystal structure of the calcium release-activated calcium channel Orai
    • Hou X., Pedi L., Diver M.M., Long S.B. Crystal structure of the calcium release-activated calcium channel Orai. Science 2012, 338(6112):1308-1313.
    • (2012) Science , vol.338 , Issue.6112 , pp. 1308-1313
    • Hou, X.1    Pedi, L.2    Diver, M.M.3    Long, S.B.4
  • 37
    • 44949272730 scopus 로고
    • A time-efficient, linear-space local similarity algorithm
    • Huang X., Miller W. A time-efficient, linear-space local similarity algorithm. Advances in Applied Mathematics 1991, 12:373-381.
    • (1991) Advances in Applied Mathematics , vol.12 , pp. 373-381
    • Huang, X.1    Miller, W.2
  • 39
    • 31944434700 scopus 로고    scopus 로고
    • Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: Two ways to promote multifunctionality
    • Ikura M., Ames J.B. Genetic polymorphism and protein conformational plasticity in the calmodulin superfamily: Two ways to promote multifunctionality. Proceedings of the National Academy of Sciences of the United States of America 2006, 103(5):1159-1164.
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , Issue.5 , pp. 1159-1164
    • Ikura, M.1    Ames, J.B.2
  • 42
    • 67349237167 scopus 로고    scopus 로고
    • A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels
    • Kawasaki T., Lange I., Feske S. A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels. Biochemical and Biophysical Research Communications 2009, 385(1):49-54.
    • (2009) Biochemical and Biophysical Research Communications , vol.385 , Issue.1 , pp. 49-54
    • Kawasaki, T.1    Lange, I.2    Feske, S.3
  • 43
    • 0344196904 scopus 로고    scopus 로고
    • SAM domains: Uniform structure, diversity of function
    • Kim C.A., Bowie J.U. SAM domains: Uniform structure, diversity of function. Trends in Biochemical Sciences 2003, 28(12):625-628.
    • (2003) Trends in Biochemical Sciences , vol.28 , Issue.12 , pp. 625-628
    • Kim, C.A.1    Bowie, J.U.2
  • 44
    • 78449232351 scopus 로고    scopus 로고
    • Activation of STIM1-Orai1 involves an intramolecular switching mechanism
    • Korzeniowski M.K., Manjarres I.M., Varnai P., Balla T. Activation of STIM1-Orai1 involves an intramolecular switching mechanism. Science Signaling 2011, 3(148):ra82.
    • (2011) Science Signaling , vol.3 , Issue.148
    • Korzeniowski, M.K.1    Manjarres, I.M.2    Varnai, P.3    Balla, T.4
  • 46
    • 84871527806 scopus 로고    scopus 로고
    • A CC-SAM, for coiled coil-sterile alpha motif, domain targets the scaffold KSR-1 to specific sites in the plasma membrane
    • ra94
    • Koveal D., Schuh-Nuhfer N., Ritt D., Page R., Morrison D.K., Peti W. A CC-SAM, for coiled coil-sterile alpha motif, domain targets the scaffold KSR-1 to specific sites in the plasma membrane. Science Signaling 2012, 5(255):ra94.
    • (2012) Science Signaling , vol.5 , Issue.255
    • Koveal, D.1    Schuh-Nuhfer, N.2    Ritt, D.3    Page, R.4    Morrison, D.K.5    Peti, W.6
  • 48
    • 0028938578 scopus 로고
    • A primary T-cell immunodeficiency associated with defective transmembrane calcium influx
    • Le Deist F., Hivroz C., Partiseti M., Thomas C., Buc H.A., Oleastro M., et al. A primary T-cell immunodeficiency associated with defective transmembrane calcium influx. Blood 1995, 85(4):1053-1062.
    • (1995) Blood , vol.85 , Issue.4 , pp. 1053-1062
    • Le Deist, F.1    Hivroz, C.2    Partiseti, M.3    Thomas, C.4    Buc, H.A.5    Oleastro, M.6
  • 52
    • 33947540912 scopus 로고    scopus 로고
    • CRAC channel activity in C. elegans is mediated by Orai1 and STIM1 homologues and is essential for ovulation and fertility
    • Lorin-Nebel C., Xing J., Yan X., Strange K. CRAC channel activity in C. elegans is mediated by Orai1 and STIM1 homologues and is essential for ovulation and fertility. The Journal of Physiology 2007, 580(Pt. 1):67-85.
    • (2007) The Journal of Physiology , vol.580 , Issue.PART 1 , pp. 67-85
    • Lorin-Nebel, C.1    Xing, J.2    Yan, X.3    Strange, K.4
  • 53
    • 47949132511 scopus 로고    scopus 로고
    • Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation
    • Luik R.M., Wang B., Prakriya M., Wu M.M., Lewis R.S. Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation. Nature 2008, 454(7203):538-542.
    • (2008) Nature , vol.454 , Issue.7203 , pp. 538-542
    • Luik, R.M.1    Wang, B.2    Prakriya, M.3    Wu, M.M.4    Lewis, R.S.5
  • 54
    • 33748548406 scopus 로고    scopus 로고
    • 2+ entry: Local activation of CRAC channels by STIM1 at ER-plasma membrane junctions
    • 2+ entry: Local activation of CRAC channels by STIM1 at ER-plasma membrane junctions. The Journal of Cell Biology 2006, 174(6):815-825.
    • (2006) The Journal of Cell Biology , vol.174 , Issue.6 , pp. 815-825
    • Luik, R.M.1    Wu, M.M.2    Buchanan, J.3    Lewis, R.S.4
  • 57
    • 67649388419 scopus 로고    scopus 로고
    • Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain
    • Maruyama Y., Ogura T., Mio K., Kato K., Kaneko T., Kiyonaka S., et al. Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain. The Journal of Biological Chemistry 2009, 284(20):13676-13685.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.20 , pp. 13676-13685
    • Maruyama, Y.1    Ogura, T.2    Mio, K.3    Kato, K.4    Kaneko, T.5    Kiyonaka, S.6
  • 59
    • 84865603245 scopus 로고    scopus 로고
    • Permeation, selectivity, and gating in store-operated CRAC channels
    • McNally B.A., Prakriya M. Permeation, selectivity, and gating in store-operated CRAC channels. The Journal of Physiology 2012, 590(Pt. 17):4179-4191.
    • (2012) The Journal of Physiology , vol.590 , Issue.PART 17 , pp. 4179-4191
    • McNally, B.A.1    Prakriya, M.2
  • 60
    • 84856961815 scopus 로고    scopus 로고
    • Gated regulation of CRAC channel ion selectivity by STIM1
    • McNally B.A., Somasundaram A., Yamashita M., Prakriya M. Gated regulation of CRAC channel ion selectivity by STIM1. Nature 2012, 482(7384):241-245.
    • (2012) Nature , vol.482 , Issue.7384 , pp. 241-245
    • McNally, B.A.1    Somasundaram, A.2    Yamashita, M.3    Prakriya, M.4
  • 62
    • 33747643506 scopus 로고    scopus 로고
    • Large store-operated calcium-selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1
    • Mercer J.C., Dehaven W.I., Smyth J.T., Wedel B., Boyles R.R., Bird G.S., et al. Large store-operated calcium-selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. The Journal of Biological Chemistry 2006, 281(34):24979-24990.
    • (2006) The Journal of Biological Chemistry , vol.281 , Issue.34 , pp. 24979-24990
    • Mercer, J.C.1    Dehaven, W.I.2    Smyth, J.T.3    Wedel, B.4    Boyles, R.R.5    Bird, G.S.6
  • 63
    • 38149040968 scopus 로고    scopus 로고
    • Orai1 subunit stoichiometry of the mammalian CRAC channel pore
    • Mignen O., Thompson J.L., Shuttleworth T.J. Orai1 subunit stoichiometry of the mammalian CRAC channel pore. The Journal of Physiology 2008, 586(2):419-425.
    • (2008) The Journal of Physiology , vol.586 , Issue.2 , pp. 419-425
    • Mignen, O.1    Thompson, J.L.2    Shuttleworth, T.J.3
  • 64
    • 77953532418 scopus 로고    scopus 로고
    • A novel native store-operated calcium channel encoded by Orai3: Selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells
    • Motiani R.K., Abdullaev I.F., Trebak M. A novel native store-operated calcium channel encoded by Orai3: Selective requirement of Orai3 versus Orai1 in estrogen receptor-positive versus estrogen receptor-negative breast cancer cells. The Journal of Biological Chemistry 2010, 285(25):19173-19183.
    • (2010) The Journal of Biological Chemistry , vol.285 , Issue.25 , pp. 19173-19183
    • Motiani, R.K.1    Abdullaev, I.F.2    Trebak, M.3
  • 66
    • 66749085475 scopus 로고    scopus 로고
    • A cytosolic homomerization and a modulatory domain within STIM1 C terminus determine coupling to ORAI1 channels
    • Muik M., Fahrner M., Derler I., Schindl R., Bergsmann J., Frischauf I., et al. A cytosolic homomerization and a modulatory domain within STIM1 C terminus determine coupling to ORAI1 channels. The Journal of Biological Chemistry 2009, 284(13):8421-8426.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.13 , pp. 8421-8426
    • Muik, M.1    Fahrner, M.2    Derler, I.3    Schindl, R.4    Bergsmann, J.5    Frischauf, I.6
  • 67
    • 79955628984 scopus 로고    scopus 로고
    • STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation
    • Muik M., Fahrner M., Schindl R., Stathopulos P., Frischauf I., Derler I., et al. STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation. The EMBO Journal 2011, 30(9):1678-1689.
    • (2011) The EMBO Journal , vol.30 , Issue.9 , pp. 1678-1689
    • Muik, M.1    Fahrner, M.2    Schindl, R.3    Stathopulos, P.4    Frischauf, I.5    Derler, I.6
  • 68
    • 43149090543 scopus 로고    scopus 로고
    • Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation
    • Muik M., Frischauf I., Derler I., Fahrner M., Bergsmann J., Eder P., et al. Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. The Journal of Biological Chemistry 2008, 283(12):8014-8022.
    • (2008) The Journal of Biological Chemistry , vol.283 , Issue.12 , pp. 8014-8022
    • Muik, M.1    Frischauf, I.2    Derler, I.3    Fahrner, M.4    Bergsmann, J.5    Eder, P.6
  • 69
  • 70
    • 0030810066 scopus 로고    scopus 로고
    • Store depletion and calcium influx
    • Parekh A.B., Penner R. Store depletion and calcium influx. Physiological Reviews 1997, 77(4):901-930.
    • (1997) Physiological Reviews , vol.77 , Issue.4 , pp. 901-930
    • Parekh, A.B.1    Penner, R.2
  • 71
    • 15544368216 scopus 로고    scopus 로고
    • Store-operated calcium channels
    • Parekh A.B., Putney J.W. Store-operated calcium channels. Physiological Reviews 2005, 85(2):757-810.
    • (2005) Physiological Reviews , vol.85 , Issue.2 , pp. 757-810
    • Parekh, A.B.1    Putney, J.W.2
  • 72
    • 61349137530 scopus 로고    scopus 로고
    • STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
    • Park C.Y., Hoover P.J., Mullins F.M., Bachhawat P., Covington E.D., Raunser S., et al. STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell 2009, 136(5):876-890.
    • (2009) Cell , vol.136 , Issue.5 , pp. 876-890
    • Park, C.Y.1    Hoover, P.J.2    Mullins, F.M.3    Bachhawat, P.4    Covington, E.D.5    Raunser, S.6
  • 73
    • 0028589615 scopus 로고
    • The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency
    • Partiseti M., Le Deist F., Hivroz C., Fischer A., Korn H., Choquet D. The calcium current activated by T cell receptor and store depletion in human lymphocytes is absent in a primary immunodeficiency. The Journal of Biological Chemistry 1994, 269(51):32327-32335.
    • (1994) The Journal of Biological Chemistry , vol.269 , Issue.51 , pp. 32327-32335
    • Partiseti, M.1    Le Deist, F.2    Hivroz, C.3    Fischer, A.4    Korn, H.5    Choquet, D.6
  • 74
    • 55549083129 scopus 로고    scopus 로고
    • The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers
    • Penna A., Demuro A., Yeromin A.V., Zhang S.L., Safrina O., Parker I., et al. The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Nature 2008, 456(7218):116-120.
    • (2008) Nature , vol.456 , Issue.7218 , pp. 116-120
    • Penna, A.1    Demuro, A.2    Yeromin, A.V.3    Zhang, S.L.4    Safrina, O.5    Parker, I.6
  • 76
    • 33748669602 scopus 로고    scopus 로고
    • Orai1 is an essential pore subunit of the CRAC channel
    • Prakriya M., Feske S., Gwack Y., Srikanth S., Rao A., Hogan P.G. Orai1 is an essential pore subunit of the CRAC channel. Nature 2006, 443(7108):230-233.
    • (2006) Nature , vol.443 , Issue.7108 , pp. 230-233
    • Prakriya, M.1    Feske, S.2    Gwack, Y.3    Srikanth, S.4    Rao, A.5    Hogan, P.G.6
  • 77
    • 0022575011 scopus 로고
    • A model for receptor-regulated calcium entry
    • Putney J.W. A model for receptor-regulated calcium entry. Cell Calcium 1986, 7(1):1-12.
    • (1986) Cell Calcium , vol.7 , Issue.1 , pp. 1-12
    • Putney, J.W.1
  • 80
    • 84862777270 scopus 로고    scopus 로고
    • Structural and functional conservation of key domains in InsP3 and ryanodine receptors
    • Seo M.D., Velamakanni S., Ishiyama N., Stathopulos P.B., Rossi A.M., Khan S.A., et al. Structural and functional conservation of key domains in InsP3 and ryanodine receptors. Nature 2012, 483(7387):108-112.
    • (2012) Nature , vol.483 , Issue.7387 , pp. 108-112
    • Seo, M.D.1    Velamakanni, S.2    Ishiyama, N.3    Stathopulos, P.B.4    Rossi, A.M.5    Khan, S.A.6
  • 81
    • 84860864275 scopus 로고    scopus 로고
    • Physiological and pathophysiological functions of SOCE in the immune system
    • Shaw P.J., Feske S. Physiological and pathophysiological functions of SOCE in the immune system. Frontiers in Bioscience (Elite Edition) 2012, 4:2253-2268.
    • (2012) Frontiers in Bioscience (Elite Edition) , vol.4 , pp. 2253-2268
    • Shaw, P.J.1    Feske, S.2
  • 82
    • 80054078476 scopus 로고    scopus 로고
    • Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
    • Sievers F., Wilm A., Dineen D., Gibson T.J., Karplus K., Li W., et al. Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega. Molecular Systems Biology 2011, 7:539.
    • (2011) Molecular Systems Biology , vol.7 , pp. 539
    • Sievers, F.1    Wilm, A.2    Dineen, D.3    Gibson, T.J.4    Karplus, K.5    Li, W.6
  • 86
    • 59449110657 scopus 로고    scopus 로고
    • Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics
    • Stathopulos P.B., Zheng L., Ikura M. Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics. The Journal of Biological Chemistry 2009, 284(2):728-732.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.2 , pp. 728-732
    • Stathopulos, P.B.1    Zheng, L.2    Ikura, M.3
  • 87
    • 53149128421 scopus 로고    scopus 로고
    • Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry
    • Stathopulos P.B., Zheng L., Li G.Y., Plevin M.J., Ikura M. Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry. Cell 2008, 135(1):110-122.
    • (2008) Cell , vol.135 , Issue.1 , pp. 110-122
    • Stathopulos, P.B.1    Zheng, L.2    Li, G.Y.3    Plevin, M.J.4    Ikura, M.5
  • 88
    • 0017780886 scopus 로고
    • The 'boy-in-the-bubble' drama
    • Stone B. The 'boy-in-the-bubble' drama. American Medical News 1977, 20(46):1+.
    • (1977) American Medical News , vol.20 , Issue.46
    • Stone, B.1
  • 90
    • 84866395344 scopus 로고    scopus 로고
    • Ryanodine receptors: Structure and function
    • Van Petegem F. Ryanodine receptors: Structure and function. The Journal of Biological Chemistry 2012, 287(38):31624-31632.
    • (2012) The Journal of Biological Chemistry , vol.287 , Issue.38 , pp. 31624-31632
    • Van Petegem, F.1
  • 92
  • 93
    • 35748956408 scopus 로고    scopus 로고
    • Visualization and manipulation of plasma membrane-endoplasmic reticulum contact sites indicates the presence of additional molecular components within the STIM1-Orai1 Complex
    • Varnai P., Toth B., Toth D.J., Hunyady L., Balla T. Visualization and manipulation of plasma membrane-endoplasmic reticulum contact sites indicates the presence of additional molecular components within the STIM1-Orai1 Complex. The Journal of Biological Chemistry 2007, 282(40):29678-29690.
    • (2007) The Journal of Biological Chemistry , vol.282 , Issue.40 , pp. 29678-29690
    • Varnai, P.1    Toth, B.2    Toth, D.J.3    Hunyady, L.4    Balla, T.5
  • 94
    • 33749987466 scopus 로고    scopus 로고
    • CRACM1 multimers form the ion-selective pore of the CRAC channel
    • Vig M., Beck A., Billingsley J.M., Lis A., Parvez S., Peinelt C., et al. CRACM1 multimers form the ion-selective pore of the CRAC channel. Current Biology 2006, 16(20):2073-2079.
    • (2006) Current Biology , vol.16 , Issue.20 , pp. 2073-2079
    • Vig, M.1    Beck, A.2    Billingsley, J.M.3    Lis, A.4    Parvez, S.5    Peinelt, C.6
  • 97
    • 0035425189 scopus 로고    scopus 로고
    • Identification and characterization of the STIM (stromal interaction molecule) gene family: Coding for a novel class of transmembrane proteins
    • Williams R.T., Manji S.S., Parker N.J., Hancock M.S., Van Stekelenburg L., Eid J.P., et al. Identification and characterization of the STIM (stromal interaction molecule) gene family: Coding for a novel class of transmembrane proteins. The Biochemical Journal 2001, 357(Pt. 3):673-685.
    • (2001) The Biochemical Journal , vol.357 , Issue.PART 3 , pp. 673-685
    • Williams, R.T.1    Manji, S.S.2    Parker, N.J.3    Hancock, M.S.4    Van Stekelenburg, L.5    Eid, J.P.6
  • 98
    • 0036537823 scopus 로고    scopus 로고
    • Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation
    • Williams R.T., Senior P.V., Van Stekelenburg L., Layton J.E., Smith P.J., Dziadek M.A. Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation. Biochimica et Biophysica Acta 2002, 1596(1):131-137.
    • (2002) Biochimica et Biophysica Acta , vol.1596 , Issue.1 , pp. 131-137
    • Williams, R.T.1    Senior, P.V.2    Van Stekelenburg, L.3    Layton, J.E.4    Smith, P.J.5    Dziadek, M.A.6
  • 99
    • 33748569838 scopus 로고    scopus 로고
    • 2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane
    • 2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane. The Journal of Cell Biology 2006, 174(6):803-813.
    • (2006) The Journal of Cell Biology , vol.174 , Issue.6 , pp. 803-813
    • Wu, M.M.1    Buchanan, J.2    Luik, R.M.3    Lewis, R.S.4
  • 103
    • 33748655172 scopus 로고    scopus 로고
    • Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai
    • Yeromin A.V., Zhang S.L., Jiang W., Yu Y., Safrina O., Cahalan M.D. Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature 2006, 443(7108):226-229.
    • (2006) Nature , vol.443 , Issue.7108 , pp. 226-229
    • Yeromin, A.V.1    Zhang, S.L.2    Jiang, W.3    Yu, Y.4    Safrina, O.5    Cahalan, M.D.6
  • 105
    • 79960648726 scopus 로고    scopus 로고
    • STIM1 and Orai1: Novel targets for vascular diseases?
    • Zhang W., Trebak M. STIM1 and Orai1: Novel targets for vascular diseases?. Science China. Life Sciences 2011, 54(8):780-785.
    • (2011) Science China. Life Sciences , vol.54 , Issue.8 , pp. 780-785
    • Zhang, W.1    Trebak, M.2
  • 111
    • 67749114700 scopus 로고    scopus 로고
    • The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels
    • Zhou Y., Mancarella S., Wang Y., Yue C., Ritchie M., Gill D.L., et al. The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels. The Journal of Biological Chemistry 2009, 284(29):19164-19168.
    • (2009) The Journal of Biological Chemistry , vol.284 , Issue.29 , pp. 19164-19168
    • Zhou, Y.1    Mancarella, S.2    Wang, Y.3    Yue, C.4    Ritchie, M.5    Gill, D.L.6


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