-
1
-
-
15544368216
-
Store-operated calcium channels
-
Parekh AB, Putney JW Jr (2005) Store-operated calcium channels. Physiol Rev 85:757-810.
-
(2005)
Physiol Rev
, vol.85
, pp. 757-810
-
-
Parekh, A.B.1
Putney Jr., J.W.2
-
2
-
-
33646576875
-
A mutation in Orai1causes immune deficiency by abrogating CRAC channel function
-
Feske S, et al. (2006) A mutation in Orai1causes immune deficiency by abrogating CRAC channel function. Nature 441:179-185.
-
(2006)
Nature
, vol.441
, pp. 179-185
-
-
Feske, S.1
-
3
-
-
33744479684
-
2+ entry
-
2+ entry. Science 312:1220-1223.
-
(2006)
Science
, vol.312
, pp. 1220-1223
-
-
Vig, M.1
-
5
-
-
33748655172
-
Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai
-
Yeromin AV, et al. (2006) Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai. Nature 443:226-229.
-
(2006)
Nature
, vol.443
, pp. 226-229
-
-
Yeromin, A.V.1
-
6
-
-
33748669602
-
Orai1 is an essential pore subunit of the CRAC channel
-
DOI 10.1038/nature05122, PII NATURE05122
-
PrakriyaM, et al. (2006) Orai1 is an essential pore subunit of the CRAC channel. Nature 443:230-233. (Pubitemid 44387613)
-
(2006)
Nature
, vol.443
, Issue.7108
, pp. 230-233
-
-
Prakriya, M.1
Feske, S.2
Gwack, Y.3
Srikanth, S.4
Rao, A.5
Hogan, P.G.6
-
7
-
-
33749987466
-
CRACM1 Multimers Form the Ion-Selective Pore of the CRAC Channel
-
DOI 10.1016/j.cub.2006.08.085, PII S0960982206021531
-
Vig M, et al. (2006) CRACM1 multimers form the ion-selective pore of the CRAC channel. Curr Biol 16:2073-2079. (Pubitemid 44573821)
-
(2006)
Current Biology
, vol.16
, Issue.20
, pp. 2073-2079
-
-
Vig, M.1
Beck, A.2
Billingsley, J.M.3
Lis, A.4
Parvez, S.5
Peinelt, C.6
Koomoa, D.L.7
Soboloff, J.8
Gill, D.L.9
Fleig, A.10
Kinet, J.-P.11
Penner, R.12
-
8
-
-
77449096553
-
STIM1 gates the store-operated calcium channel ORAI1 in vitro
-
Zhou Y, et al. (2010) STIM1 gates the store-operated calcium channel ORAI1 in vitro. Nat Struct Mol Biol 17:112-116.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 112-116
-
-
Zhou, Y.1
-
9
-
-
34247853462
-
Dissecting ICRAC, a store-operated calcium current
-
Hogan PG, Rao A (2007) Dissecting ICRAC, a store-operated calcium current. Trends Biochem Sci 32:235-245.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 235-245
-
-
Hogan, P.G.1
Rao, A.2
-
10
-
-
70349098735
-
Capacitative calcium entry: From concept to molecules
-
Putney JW (2009) Capacitative calcium entry: From concept to molecules. Immunol Rev 231:10-22.
-
(2009)
Immunol Rev
, vol.231
, pp. 10-22
-
-
Putney, J.W.1
-
11
-
-
77950377028
-
Molecular basis of calcium signaling in lymphocytes: STIM and ORAI
-
Hogan PG, Lewis RS, Rao A (2010) Molecular basis of calcium signaling in lymphocytes: STIM and ORAI. Annu Rev Immunol 28:491-533.
-
(2010)
Annu Rev Immunol
, vol.28
, pp. 491-533
-
-
Hogan, P.G.1
Lewis, R.S.2
Rao, A.3
-
12
-
-
71449095831
-
2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia
-
2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia. J Allergy Clin Immunol 124:1311-1318.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 1311-1318
-
-
McCarl, C.A.1
-
13
-
-
50249165416
-
Hair loss and defective T- and B-cell function in mice lacking ORAI1
-
Gwack Y, et al. (2008) Hair loss and defective T- and B-cell function in mice lacking ORAI1. Mol Cell Biol 28:5209-5222.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5209-5222
-
-
Gwack, Y.1
-
14
-
-
37349067978
-
Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels
-
DOI 10.1038/ni1550, PII NI1550
-
Vig M, et al. (2008) Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels. Nat Immunol 9:89-96. (Pubitemid 350286208)
-
(2008)
Nature Immunology
, vol.9
, Issue.1
, pp. 89-96
-
-
Vig, M.1
Dehaven, W.I.2
Bird, G.S.3
Billingsley, J.M.4
Wang, H.5
Rao, P.E.6
Hutchings, A.B.7
Jouvin, M.-H.8
Putney, J.W.9
Kinet, J.-P.10
-
15
-
-
21044439334
-
2+ channel function
-
2+ channel function. J Cell Biol 169:435-445.
-
(2005)
J Cell Biol
, vol.169
, pp. 435-445
-
-
Roos, J.1
-
16
-
-
21844432686
-
2+ influx
-
2+ influx. Curr Biol 15:1235-1241.
-
(2005)
Curr Biol
, vol.15
, pp. 1235-1241
-
-
Liou, J.1
-
17
-
-
27144515996
-
2+ store to the plasma membrane
-
2+ store to the plasma membrane. Nature 437:902-905.
-
(2005)
Nature
, vol.437
, pp. 902-905
-
-
Zhang, S.L.1
-
18
-
-
33748569838
-
2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane
-
2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane. J Cell Biol 174:803-813.
-
(2006)
J Cell Biol
, vol.174
, pp. 803-813
-
-
Wu, M.M.1
-
19
-
-
33748548406
-
2+ entry: Local activation of CRAC channels by STIM1 at ER-plasma membrane junctions
-
2+ entry: Local activation of CRAC channels by STIM1 at ER-plasma membrane junctions. J Cell Biol 174:815-825.
-
(2006)
J Cell Biol
, vol.174
, pp. 815-825
-
-
Luik, R.M.1
-
20
-
-
53149128421
-
Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry
-
Stathopulos PB, et al. (2008) Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry. Cell 135:110-122.
-
(2008)
Cell
, vol.135
, pp. 110-122
-
-
Stathopulos, P.B.1
-
21
-
-
0023224051
-
Global flexibility in a sensory receptor: A site-directed cross-linking approach
-
Falke JJ, Koshland DE Jr (1987) Global flexibility in a sensory receptor: A site-directed cross-linking approach. Science 237:1596-1600.
-
(1987)
Science
, vol.237
, pp. 1596-1600
-
-
Falke, J.J.1
Koshland Jr., D.E.2
-
22
-
-
0026605299
-
Determination of transmembrane protein structure by disulfide cross-linking: The Escherichia coli Tar receptor
-
Pakula AA, Simon MI (1992) Determination of transmembrane protein structure by disulfide cross-linking: The Escherichia coli Tar receptor. Proc Natl Acad Sci USA 89:4144-4148.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4144-4148
-
-
Pakula, A.A.1
Simon, M.I.2
-
24
-
-
34247339504
-
Biochemical and functional characterization of orai proteins
-
DOI 10.1074/jbc.M609630200
-
Gwack Y, et al. (2007) Biochemical and functional characterization of Orai proteins. J Biol Chem 282:16232-16243. (Pubitemid 47100386)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.22
, pp. 16232-16243
-
-
Gwack, Y.1
Srikanth, S.2
Feske, S.3
Cruz-Guilloty, F.4
Oh-hora, M.5
Neems, D.S.6
Hogan, P.G.7
Rao, A.8
-
25
-
-
0030479442
-
Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach
-
Guzzo A, et al. (1996) Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach. J Bacteriol 178:7295-7303. (Pubitemid 26424647)
-
(1996)
Journal of Bacteriology
, vol.178
, Issue.24
, pp. 7295-7303
-
-
Guzzo, A.1
Lee, M.H.2
Oda, K.3
Walker, G.C.4
-
26
-
-
0031056669
-
Analysis of protein structure in intact cells: Crosslinking in vivo between introduced cysteines in the transmembrane domain of a bacterial chemoreceptor
-
Hughson AG, Lee GF, Hazelbauer GL (1997) Analysis of protein structure in intact cells: Crosslinking in vivo between introduced cysteines in the transmembrane domain of a bacterial chemoreceptor. Protein Sci 6:315-322.
-
(1997)
Protein Sci
, vol.6
, pp. 315-322
-
-
Hughson, A.G.1
Lee, G.F.2
Hazelbauer, G.L.3
-
27
-
-
38149040968
-
Orai1 subunit stoichiometry of the mammalian CRAC channel pore
-
Mignen O, Thompson JL, Shuttleworth TJ (2008) Orai1 subunit stoichiometry of the mammalian CRAC channel pore. J Physiol 586:419-425.
-
(2008)
J Physiol
, vol.586
, pp. 419-425
-
-
Mignen, O.1
Thompson, J.L.2
Shuttleworth, T.J.3
-
28
-
-
51649121732
-
Functional stoichiometry of the unitary calcium-release-activated calcium channel
-
Ji W, et al. (2008) Functional stoichiometry of the unitary calcium-release-activated calcium channel. Proc Natl Acad Sci USA 105:13668-13673.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13668-13673
-
-
Ji, W.1
-
29
-
-
55549083129
-
The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers
-
Penna A, et al. (2008) The CRAC channel consists of a tetramer formed by Stim-induced dimerization of Orai dimers. Nature 456:116-120.
-
(2008)
Nature
, vol.456
, pp. 116-120
-
-
Penna, A.1
-
30
-
-
69949095093
-
2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits
-
2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits. J Physiol 587:4181-4197.
-
(2009)
J Physiol
, vol.587
, pp. 4181-4197
-
-
Mignen, O.1
Thompson, J.L.2
Shuttleworth, T.J.3
-
31
-
-
48049094820
-
2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size
-
Schindl R, et al. (2008) 2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size. J Biol Chem 283:20261-20267.
-
(2008)
J Biol Chem
, vol.283
, pp. 20261-20267
-
-
Schindl, R.1
-
32
-
-
35648980119
-
2+-dependent fast inactivation of CRAC channels: Evidence for coupling of permeation and gating
-
2+-dependent fast inactivation of CRAC channels: Evidence for coupling of permeation and gating. J Gen Physiol 130:525-540.
-
(2007)
J Gen Physiol
, vol.130
, pp. 525-540
-
-
Yamashita, M.1
-
33
-
-
47249087342
-
2+ channel induced by mutation of the Orai1 protein
-
2+ channel induced by mutation of the Orai1 protein. J Biol Chem 283:14938-14945.
-
(2008)
J Biol Chem
, vol.283
, pp. 14938-14945
-
-
Spassova, M.A.1
-
34
-
-
61349137530
-
STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1
-
Park CY, et al. (2009) STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1. Cell 136:876-890.
-
(2009)
Cell
, vol.136
, pp. 876-890
-
-
Park, C.Y.1
-
35
-
-
67650100398
-
Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant
-
Derler I, et al. (2009) Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant. J Biol Chem 284:15903-15915.
-
(2009)
J Biol Chem
, vol.284
, pp. 15903-15915
-
-
Derler, I.1
-
36
-
-
43149090543
-
Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation
-
Muik M, et al. (2008) Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. J Biol Chem 283:8014-8022.
-
(2008)
J Biol Chem
, vol.283
, pp. 8014-8022
-
-
Muik, M.1
-
37
-
-
56649094581
-
STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy
-
Navarro-Borelly L, et al. (2008) STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy. J Physiol 586:5383-5401.
-
(2008)
J Physiol
, vol.586
, pp. 5383-5401
-
-
Navarro-Borelly, L.1
-
39
-
-
76049099797
-
Structural determinants of ion permeation in CRAC channels
-
McNally BA, et al. (2009) Structural determinants of ion permeation in CRAC channels. Proc Natl Acad Sci USA 106:22516-22521.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 22516-22521
-
-
McNally, B.A.1
-
40
-
-
0033050808
-
Iodine and disinfection: Theoretical study on mode of action, efficiency, stability, and analytical aspects in the aqueous system
-
Gottardi W (1999) Iodine and disinfection: Theoretical study on mode of action, efficiency, stability, and analytical aspects in the aqueous system. Arch Pharm (Weinheim, Ger) 332:151-157.
-
(1999)
Arch Pharm (Weinheim, Ger)
, vol.332
, pp. 151-157
-
-
Gottardi, W.1
-
41
-
-
0000207681
-
TMBASE - A database of membrane spanning protein segments
-
abstr
-
Hofmann K, Stoffel W (1993) TMBASE - a database of membrane spanning protein segments. Biol Chem 374:166 (abstr).
-
(1993)
Biol Chem
, vol.374
, pp. 166
-
-
Hofmann, K.1
Stoffel, W.2
-
42
-
-
0034786532
-
The HMMTOP transmembrane topology prediction server
-
Tusnády GE, Simon I (2001) The HMMTOP transmembrane topology prediction server. Bioinformatics 17(9):849-850.
-
(2001)
Bioinformatics
, vol.17
, Issue.9
, pp. 849-850
-
-
Tusnády, G.E.1
Simon, I.2
-
43
-
-
0035910270
-
Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
-
DOI 10.1006/jmbi.2000.4315
-
Krogh A, et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes. J Mol Biol 305:567-580. (Pubitemid 33032862)
-
(2001)
Journal of Molecular Biology
, vol.305
, Issue.3
, pp. 567-580
-
-
Krogh, A.1
Larsson, B.2
Von Heijne, G.3
Sonnhammer, E.L.L.4
|