Pharmacology of ORAI channels as a tool to understand their physiological functions

Expert Review of Clinical Pharmacology

Volumn 3, Issue 3, 2010, Pages 291-303

  Bogeski, Ivan ^a   Al Ansary, Dalia ^a   Qu, Bin ^a   Niemeyer, Barbara A ^a   Hoth, Markus ^a   Peinelt, Christine ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

2 aminoethoxydiphenyl borate; BTP2; Ca2+ release activated Ca 2+ channels; G418; Immune cells; Ion channel pharmacology; ORAI1, 2 and 3; STIM1 and 2

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; ANTIBIOTIC G 418; BTP 2; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 2; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 3; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 5; N [4 [3,5 BIS(TRIFLUOROMETHYL) 1H PYRAZOL 1 YL]PHENYL] 4 METHYL 1,2,3 THIADIAZOLE 5 CARBOXAMIDE; STROMAL INTERACTION MOLECULE 1; STROMAL INTERACTION MOLECULE 2; UNCLASSIFIED DRUG; YM 58483;

ASTHMA; AUTOIMMUNE DISEASE; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM SIGNALING; CALCIUM TRANSPORT; CD4+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CHANNEL GATING; CHRONIC INFLAMMATION; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM; ENTERITIS; GENE MUTATION; GRAFT VERSUS HOST REACTION; HELPER CELL; HUMAN; IC 50; LAMINA PROPRIA; LYMPHOCYTE PROLIFERATION; NONHUMAN; OLIGOMERIZATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVIEW; T LYMPHOCYTE ACTIVATION;

EID: 77952569203     PISSN: 17512433     EISSN: None     Source Type: Journal    
DOI: 10.1586/ecp.10.23     Document Type: Review

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