메뉴 건너뛰기




Volumn 25, Issue 8, 2013, Pages 742-752

The beneficial effects of early short-term exercise in the offspring of obese mothers are accompanied by alterations in the hypothalamic gene expression of appetite regulators and fto (fat mass and obesity associated) gene

Author keywords

Exercise; Fat mass and obesity associated gene; Hypothalamus; Maternal obesity; Neuropeptide Y; Pro opiomelanocortin

Indexed keywords

INSULIN; LEPTIN; MESSENGER RNA; PROOPIOMELANOCORTIN; TRIACYLGLYCEROL;

EID: 84880734543     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/jne.12053     Document Type: Article
Times cited : (28)

References (50)
  • 1
    • 79958182036 scopus 로고    scopus 로고
    • Food portion patterns and trends among U.S. children and the relationship to total eating occasion size, 1977-2006
    • Piernas C, Popkin BM. Food portion patterns and trends among U.S. children and the relationship to total eating occasion size, 1977-2006. J Nutr 2011; 141: 1159-1164.
    • (2011) J Nutr , vol.141 , pp. 1159-1164
    • Piernas, C.1    Popkin, B.M.2
  • 2
    • 0037055715 scopus 로고    scopus 로고
    • Childhood obesity: public-health crisis, common sense cure
    • Ebbeling CB, Pawlak DB, Ludwig DS. Childhood obesity: public-health crisis, common sense cure. Lancet 2002; 360: 473-482.
    • (2002) Lancet , vol.360 , pp. 473-482
    • Ebbeling, C.B.1    Pawlak, D.B.2    Ludwig, D.S.3
  • 3
    • 0036094537 scopus 로고    scopus 로고
    • Predictability of childhood adiposity and insulin for developing insulin resistance syndrome (syndrome X) in young adulthood: the Bogalusa Heart Study
    • Srinivasan SR, Myers L, Berenson GS. Predictability of childhood adiposity and insulin for developing insulin resistance syndrome (syndrome X) in young adulthood: the Bogalusa Heart Study. Diabetes 2002; 51: 204-209.
    • (2002) Diabetes , vol.51 , pp. 204-209
    • Srinivasan, S.R.1    Myers, L.2    Berenson, G.S.3
  • 4
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN. A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3
  • 5
    • 15544369982 scopus 로고    scopus 로고
    • Developmental origins of the metabolic syndrome: prediction, plasticity, and programming
    • McMillen IC, Robinson JS. Developmental origins of the metabolic syndrome: prediction, plasticity, and programming. Physiol Rev 2005; 85: 571-633.
    • (2005) Physiol Rev , vol.85 , pp. 571-633
    • McMillen, I.C.1    Robinson, J.S.2
  • 6
    • 0036833795 scopus 로고    scopus 로고
    • Fetal programming of coronary heart disease
    • Barker DJ. Fetal programming of coronary heart disease. Trends Endocrinol Metab 2002; 13: 364-368.
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 364-368
    • Barker, D.J.1
  • 7
    • 70450060723 scopus 로고    scopus 로고
    • Early life influences on obesity risk - maternal overnutrition and programming of obesity
    • Morris M. Early life influences on obesity risk - maternal overnutrition and programming of obesity. Expert Rev Endocrinol Metab 2009; 4: 625-637.
    • (2009) Expert Rev Endocrinol Metab , vol.4 , pp. 625-637
    • Morris, M.1
  • 8
    • 66149172037 scopus 로고    scopus 로고
    • Maternal and child obesity: the casual link
    • Oken E. Maternal and child obesity: the casual link. Obstet Gynecol Clin North Am 2010; 36: 361-377.
    • (2010) Obstet Gynecol Clin North Am , vol.36 , pp. 361-377
    • Oken, E.1
  • 9
    • 77956206292 scopus 로고    scopus 로고
    • Obesity, insulin resistance, and pregnancy outcome
    • Catalano PM. Obesity, insulin resistance, and pregnancy outcome. Reproduction 2010; 140: 365-371.
    • (2010) Reproduction , vol.140 , pp. 365-371
    • Catalano, P.M.1
  • 10
    • 0028791014 scopus 로고
    • Exercise in the treatment of childhood obesity
    • Epstein LH. Exercise in the treatment of childhood obesity. Int J Obes Relat Metab Disord 1995; 19(Suppl. 4): S117-S121.
    • (1995) Int J Obes Relat Metab Disord , vol.19 , Issue.SUPPL. 4
    • Epstein, L.H.1
  • 13
    • 0842309060 scopus 로고    scopus 로고
    • Energy balance and body composition in sports and exercise
    • Loucks AB. Energy balance and body composition in sports and exercise. J Sports Sci 2004; 22: 1-14.
    • (2004) J Sports Sci , vol.22 , pp. 1-14
    • Loucks, A.B.1
  • 14
    • 38949197452 scopus 로고    scopus 로고
    • Three weeks of early-onset exercise prolongs obesity resistance in DIO rats after exercise cessation
    • Patterson CM, Dunn-Meynell AA, Levin BE. Three weeks of early-onset exercise prolongs obesity resistance in DIO rats after exercise cessation. Am J Physiol Regul Integr Comp Physiol 2008; 294: R290-R301.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Patterson, C.M.1    Dunn-Meynell, A.A.2    Levin, B.E.3
  • 15
    • 64149099887 scopus 로고    scopus 로고
    • Three weeks of postweaning exercise in DIO rats produces prolonged increases in central leptin sensitivity and signaling
    • Patterson CM, Bouret SG, Dunn-Meynell AA, Levin BE. Three weeks of postweaning exercise in DIO rats produces prolonged increases in central leptin sensitivity and signaling. Am J Physiol Regul Integr Comp Physiol 2009; 296: R537-R548.
    • (2009) Am J Physiol Regul Integr Comp Physiol , vol.296
    • Patterson, C.M.1    Bouret, S.G.2    Dunn-Meynell, A.A.3    Levin, B.E.4
  • 17
    • 1642276360 scopus 로고    scopus 로고
    • Chronic exercise lowers the defended body weight gain and adiposity in diet-induced obese rats
    • Levin BE, Dunn-Meynell AA. Chronic exercise lowers the defended body weight gain and adiposity in diet-induced obese rats. Am J Physiol Regul Integr Comp Physiol 2004; 286: R771-R778.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • Levin, B.E.1    Dunn-Meynell, A.A.2
  • 18
    • 80053252501 scopus 로고    scopus 로고
    • Early hypothalamic FTO overexpression in response to maternal obesity - potential contribution to postweaning hyperphagia
    • Caruso V, Chen H, Morris MJ. Early hypothalamic FTO overexpression in response to maternal obesity - potential contribution to postweaning hyperphagia. PLoS ONE 2011; 6: e25261.
    • (2011) PLoS ONE , vol.6
    • Caruso, V.1    Chen, H.2    Morris, M.J.3
  • 19
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001; 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 20
    • 67650901466 scopus 로고    scopus 로고
    • Hypothalamic neuroendocrine circuitary is programmed by maternal obesity: interaction with postnatal nutritional environment
    • Chen H, Simar D, Morris MJ. Hypothalamic neuroendocrine circuitary is programmed by maternal obesity: interaction with postnatal nutritional environment. PLoS ONE 2009; 4: e6259.
    • (2009) PLoS ONE , vol.4
    • Chen, H.1    Simar, D.2    Morris, M.J.3
  • 21
    • 0027385549 scopus 로고
    • The influence of exercise on energy balance changes induced by ventromedial hypothalamic lesion in the rat
    • Monda M, Amaro S, De Luca B. The influence of exercise on energy balance changes induced by ventromedial hypothalamic lesion in the rat. Physiol Behav 1993; 54: 1057-1061.
    • (1993) Physiol Behav , vol.54 , pp. 1057-1061
    • Monda, M.1    Amaro, S.2    De Luca, B.3
  • 22
    • 0036278737 scopus 로고    scopus 로고
    • The effects of high-fat diet on exercise-induced changes in metabolic parameters in Zucker fa/fa rats
    • Kibenge MT, Chan CB. The effects of high-fat diet on exercise-induced changes in metabolic parameters in Zucker fa/fa rats. Metabolism 2002; 51: 708-715.
    • (2002) Metabolism , vol.51 , pp. 708-715
    • Kibenge, M.T.1    Chan, C.B.2
  • 23
    • 39449087112 scopus 로고    scopus 로고
    • Brain neuropeptide Y and CCK and peripheral adipokine receptors: temporal response in obesity induced by palatable diet
    • Morris MJ, Chen H, Watts R, Shulkes A, Cameron-Smith D. Brain neuropeptide Y and CCK and peripheral adipokine receptors: temporal response in obesity induced by palatable diet. Int J Obes 2007; 32: 249-258.
    • (2007) Int J Obes , vol.32 , pp. 249-258
    • Morris, M.J.1    Chen, H.2    Watts, R.3    Shulkes, A.4    Cameron-Smith, D.5
  • 25
    • 82455168243 scopus 로고    scopus 로고
    • Endurance exercise is a leptin signaling mimetic in hypothalamus of Wistar rats
    • Zhao J, Tian Y, Xu J, Liu D, Wang X, Zhao B. Endurance exercise is a leptin signaling mimetic in hypothalamus of Wistar rats. Lipids Health Dis 2011; 10: 225.
    • (2011) Lipids Health Dis , vol.10 , pp. 225
    • Zhao, J.1    Tian, Y.2    Xu, J.3    Liu, D.4    Wang, X.5    Zhao, B.6
  • 27
    • 84866705627 scopus 로고    scopus 로고
    • From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior
    • Williams KW, Elmquist JK. From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior. Nat Neurosci 2012; 15: 1350-1355.
    • (2012) Nat Neurosci , vol.15 , pp. 1350-1355
    • Williams, K.W.1    Elmquist, J.K.2
  • 30
    • 12844278828 scopus 로고    scopus 로고
    • Effects of fasting, leptin, and insulin on AGRP and POMC peptide release in the hypothalamus
    • Breen TL, Conwell IM, Wardlaw SL. Effects of fasting, leptin, and insulin on AGRP and POMC peptide release in the hypothalamus. Brain Res 2005; 1032: 141-148.
    • (2005) Brain Res , vol.1032 , pp. 141-148
    • Breen, T.L.1    Conwell, I.M.2    Wardlaw, S.L.3
  • 32
    • 77957258099 scopus 로고    scopus 로고
    • Maternal high-fat diers methylation and gene expression of dopamine and opioid-related genes
    • Vucetic Z, Kimmel J, Totoki K, Hollenbeck E, Reyes TM. Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes. Endocrinology 2010; 151: 4756-4764.
    • (2010) Endocrinology , vol.151 , pp. 4756-4764
    • Vucetic, Z.1    Kimmel, J.2    Totoki, K.3    Hollenbeck, E.4    Reyes, T.M.5
  • 33
    • 77649303960 scopus 로고    scopus 로고
    • Hypothalamic-specific manipulation of FTO, the ortholog of the human obesity gene FTO, affects food intake in rats
    • Tung YC, Ayuso E, Shan X, Bosch F, O'Rahilly S, Coll AP, Yeo GS. Hypothalamic-specific manipulation of FTO, the ortholog of the human obesity gene FTO, affects food intake in rats. PLoS ONE 2010; 5: e8771.
    • (2010) PLoS ONE , vol.5
    • Tung, Y.C.1    Ayuso, E.2    Shan, X.3    Bosch, F.4    O'Rahilly, S.5    Coll, A.P.6    Yeo, G.S.7
  • 35
    • 42249110521 scopus 로고    scopus 로고
    • FTO: the first gene contributing to common forms of human obesity
    • Loos RJF, Bouchard C. FTO: the first gene contributing to common forms of human obesity. Obes Rev 2008; 9: 246-250.
    • (2008) Obes Rev , vol.9 , pp. 246-250
    • Loos, R.J.F.1    Bouchard, C.2
  • 39
    • 77957940963 scopus 로고    scopus 로고
    • Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice
    • Kawanishi N, Yano H, Yokogawa Y, Suzuki K. Exercise training inhibits inflammation in adipose tissue via both suppression of macrophage infiltration and acceleration of phenotypic switching from M1 to M2 macrophages in high-fat-diet-induced obese mice. Exerc Immunol Rev 2010; 16: 105-118.
    • (2010) Exerc Immunol Rev , vol.16 , pp. 105-118
    • Kawanishi, N.1    Yano, H.2    Yokogawa, Y.3    Suzuki, K.4
  • 40
    • 67349210207 scopus 로고    scopus 로고
    • Effects of diet and exercise on metabolic disturbances in high-fat diet-fed mice
    • Vieira VJ, Valentine RJ, Wilund KR, Woods JA. Effects of diet and exercise on metabolic disturbances in high-fat diet-fed mice. Cytokine 2009; 46: 339-345.
    • (2009) Cytokine , vol.46 , pp. 339-345
    • Vieira, V.J.1    Valentine, R.J.2    Wilund, K.R.3    Woods, J.A.4
  • 44
    • 0031965513 scopus 로고    scopus 로고
    • Sterol regulatory element binding proteins (SREBPs): controllers of lipid synthesis and cellular uptake
    • Brown MS, Goldstein JL. Sterol regulatory element binding proteins (SREBPs): controllers of lipid synthesis and cellular uptake. Nutr Rev 1998; 56(2 Pt 2): S1-S3.
    • (1998) Nutr Rev , vol.2 , Issue.PART 2
    • Brown, M.S.1    Goldstein, J.L.2
  • 45
    • 0029584665 scopus 로고
    • Hormonal and nutritional control of the fatty acid synthase promoter in transgenic mice
    • Soncini M, Yet SF, Moon Y, Chun JY, Sul HS. Hormonal and nutritional control of the fatty acid synthase promoter in transgenic mice. J Biol Chem 1995; 270: 30339-30343.
    • (1995) J Biol Chem , vol.270 , pp. 30339-30343
    • Soncini, M.1    Yet, S.F.2    Moon, Y.3    Chun, J.Y.4    Sul, H.S.5
  • 46
    • 0031968790 scopus 로고    scopus 로고
    • Exercise training down-regulates hepatic lipogenic enzymes in meal-fed rats: fructose versus complex-carbohydrate diets
    • Fiebig R, Griffiths MA, Gore MT, Baker DH, Oscai L, Ney DM, Ji LL. Exercise training down-regulates hepatic lipogenic enzymes in meal-fed rats: fructose versus complex-carbohydrate diets. J Nutr 1998; 128: 810-817.
    • (1998) J Nutr , vol.128 , pp. 810-817
    • Fiebig, R.1    Griffiths, M.A.2    Gore, M.T.3    Baker, D.H.4    Oscai, L.5    Ney, D.M.6    Ji, L.L.7
  • 47
    • 0022345916 scopus 로고
    • Serum lipoproteins of the Zucker rat in response to an endurance running program
    • Durstine J, Kenno K, Shepherd R. Serum lipoproteins of the Zucker rat in response to an endurance running program. Med Sci Sports Exerc 1985; 17: 567-573.
    • (1985) Med Sci Sports Exerc , vol.17 , pp. 567-573
    • Durstine, J.1    Kenno, K.2    Shepherd, R.3
  • 49
    • 77957277779 scopus 로고    scopus 로고
    • Relationship between blood glucose levels and hepatic FTO mRNA expression in mice
    • Poritsanos NJ, Lew PS, Mizuno TM. Relationship between blood glucose levels and hepatic FTO mRNA expression in mice. Biochem Biophys Res Commun 2010; 400: 713-717.
    • (2010) Biochem Biophys Res Commun , vol.400 , pp. 713-717
    • Poritsanos, N.J.1    Lew, P.S.2    Mizuno, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.