-
1
-
-
0014142582
-
The significance of basal insulin levels in the evaluation of the insulin response to glucose in diabetic and nondiabetic subjects
-
Bagdade JD, Bierman EL, Porte Jr D (1967) The significance of basal insulin levels in the evaluation of the insulin response to glucose in diabetic and nondiabetic subjects. J Clin Invest 46:1549-1557.
-
(1967)
J Clin Invest
, vol.46
, pp. 1549-1557
-
-
Bagdade, J.D.1
Bierman, E.L.2
Porte D., Jr.3
-
4
-
-
0027361094
-
Saturable transport of insulin from plasma into the central nervous system of dogs in vivo: A mechanism for regulated insulin delivery to the brain
-
Baura G, Foster D, Porte Jr D, Kahn SE, Bergman RN, Cobelli C, Schwartz MW (1993) Saturable transport of insulin from plasma into the central nervous system of dogs in vivo: A mechanism for regulated insulin delivery to the brain. J Clin Invest 92:1824-1830.
-
(1993)
J Clin Invest
, vol.92
, pp. 1824-1830
-
-
Baura, G.1
Foster, D.2
Porte D., Jr.3
Kahn, S.E.4
Bergman, R.N.5
Cobelli, C.6
Schwartz, M.W.7
-
5
-
-
0032014178
-
Identification of SOCS-3 as a potential mediator of central leptin resistance. Identification of SOCS-3 as a potential mediator of central leptin resistance
-
Bjorbaek C, Elmquist JK, Frantz JD, Shoelson SE, Flier JS (1998) Identification of SOCS-3 as a potential mediator of central leptin resistance. Identification of SOCS-3 as a potential mediator of central leptin resistance. Mol Cell 1:619-625.
-
(1998)
Mol Cell
, vol.1
, pp. 619-625
-
-
Bjorbaek, C.1
Elmquist, J.K.2
Frantz, J.D.3
Shoelson, S.E.4
Flier, J.S.5
-
6
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
Brüning JC, Gautam D, Burks DJ, Gillette J, Schubert M, Orban PC, Klein R, Krone W, Müller-Wieland D, Kahn CR (2000) Role of brain insulin receptor in control of body weight and reproduction. Science 289:2122-2125.
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Brüning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
Orban, P.C.6
Klein, R.7
Krone, W.8
Müller-Wieland, D.9
Kahn, C.R.10
-
7
-
-
0029069317
-
A comparison between the effects of intraventricular insulin and intraperitoneal LiCl on three measures sensitive to emetic agents
-
Chavez M, Seeley RJ, Woods SC (1995) A comparison between the effects of intraventricular insulin and intraperitoneal LiCl on three measures sensitive to emetic agents. Behav Neurosci 109:547-550.
-
(1995)
Behav Neurosci
, vol.109
, pp. 547-550
-
-
Chavez, M.1
Seeley, R.J.2
Woods, S.C.3
-
8
-
-
0030928715
-
Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus
-
Cheung CC, Clifton DK, Steiner RA (1997) Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus. Endocrinology 138:4489-4492.
-
(1997)
Endocrinology
, vol.138
, pp. 4489-4492
-
-
Cheung, C.C.1
Clifton, D.K.2
Steiner, R.A.3
-
9
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley MA, Smart JL, Rubinstein M, Cerdan MG, Diano S, Horvath TL, Cone RD, Low MJ (2001) Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411:480-484.
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
Smart, J.L.2
Rubinstein, M.3
Cerdan, M.G.4
Diano, S.5
Horvath, T.L.6
Cone, R.D.7
Low, M.J.8
-
10
-
-
0034717062
-
SOCS-3 is an insulin-induced negative regulator of insulin signaling
-
Emanuelli B, Peraldi P, Filloux C, Sawka-Verhelle D, Hilton D, Van Obberghen E (2000) SOCS-3 is an insulin-induced negative regulator of insulin signaling. J Biol Chem 275:15985-15991.
-
(2000)
J Biol Chem
, vol.275
, pp. 15985-15991
-
-
Emanuelli, B.1
Peraldi, P.2
Filloux, C.3
Sawka-Verhelle, D.4
Hilton, D.5
Van Obberghen, E.6
-
11
-
-
0030614331
-
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
-
Fan W, Boston B, Kesterson R, Hruby V, Cone R (1997) Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385:165-168.
-
(1997)
Nature
, vol.385
, pp. 165-168
-
-
Fan, W.1
Boston, B.2
Kesterson, R.3
Hruby, V.4
Cone, R.5
-
12
-
-
0033559446
-
Role of the CNS melanocortin system in the response to overfeeding
-
Hagan M, Rushing P, Schwartz M, Yagaloff K, Burn P, Woods S, Seeley R (1999) Role of the CNS melanocortin system in the response to overfeeding. J Neurosci 19:2362-2367.
-
(1999)
J Neurosci
, vol.19
, pp. 2362-2367
-
-
Hagan, M.1
Rushing, P.2
Schwartz, M.3
Yagaloff, K.4
Burn, P.5
Woods, S.6
Seeley, R.7
-
13
-
-
0033870091
-
Long-term orexigenic effects of AgRP-(83-132) involve mechanisms other than melanocortin receptor blockade
-
Hagan MM, Rushing PA, Pritchard LM, Schwartz MW, Strack AM, Van der Ploeg HT, Woods SC, Seeley RJ (2000) Long-term orexigenic effects of AgRP-(83-132) involve mechanisms other than melanocortin receptor blockade. Am J Physiol 279:R47-R52.
-
(2000)
Am J Physiol
, vol.279
-
-
Hagan, M.M.1
Rushing, P.A.2
Pritchard, L.M.3
Schwartz, M.W.4
Strack, A.M.5
Van der Ploeg, H.T.6
Woods, S.C.7
Seeley, R.J.8
-
14
-
-
3242829141
-
Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining. Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining
-
Hunyady B, Krempels K, Harta G, Mezey E (1996) Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining. Immunohistochemical signal amplification by catalyzed reporter deposition and its application in double immunostaining. J Histochem Cytochem 44:1353-1362.
-
(1996)
J Histochem Cytochem
, vol.44
, pp. 1353-1362
-
-
Hunyady, B.1
Krempels, K.2
Harta, G.3
Mezey, E.4
-
15
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, Berkemeier LR, Gu W, Kesterson RA, Boston BA, Cone RD, Smith FJ, Campfield LA, Burn P, Lee F (1997) Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88:131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
Lynch, C.A.2
Fairchild-Huntress, V.3
Dunmore, J.H.4
Fang, Q.5
Berkemeier, L.R.6
Gu, W.7
Kesterson, R.A.8
Boston, B.A.9
Cone, R.D.10
Smith, F.J.11
Campfield, L.A.12
Burn, P.13
Lee, F.14
-
16
-
-
0033042670
-
STZ-induced diabetes decreases and insulin normalizes POMC mRNA in arcuate nucleus and pituitary in rats
-
Kim EM, Grace MK, Welch CC, Billington CJ, Levine AS (1999) STZ-induced diabetes decreases and insulin normalizes POMC mRNA in arcuate nucleus and pituitary in rats. Am J Physiol 276: R1320-R1326.
-
(1999)
Am J Physiol
, vol.276
-
-
Kim, E.M.1
Grace, M.K.2
Welch, C.C.3
Billington, C.J.4
Levine, A.S.5
-
17
-
-
0026523608
-
Chronic intrahyphothalamic infusions of insulin or insulin antibodies alter body weight and food intake in the rat
-
McGowan MK, Andrews KM, Grossman SP (1992) Chronic intrahyphothalamic infusions of insulin or insulin antibodies alter body weight and food intake in the rat. Physol Behav 51:753-766.
-
(1992)
Physol Behav
, vol.51
, pp. 753-766
-
-
McGowan, M.K.1
Andrews, K.M.2
Grossman, S.P.3
-
18
-
-
0034657845
-
The use of TaqMan RT-PCR assays for semiquantitative analysis of gene expression in CNS tissues and disease models
-
Medhurst AD, Harrison DC, Read SJ, Campbell CA, Robbins MJ, Pangalos MN (2000) The use of TaqMan RT-PCR assays for semiquantitative analysis of gene expression in CNS tissues and disease models. J Neurosci Methods 98:9-20.
-
(2000)
J Neurosci Methods
, vol.98
, pp. 9-20
-
-
Medhurst, A.D.1
Harrison, D.C.2
Read, S.J.3
Campbell, C.A.4
Robbins, M.J.5
Pangalos, M.N.6
-
19
-
-
0031888157
-
Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and in ob/ob and db/db mice, but is stimulated by leptin
-
Mizuno T, Kleopoulos S, Bergen H, Roberts J, Priest C, Mobbs C (1998) Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and in ob/ob and db/db mice, but is stimulated by leptin. Diabetes 47:294-297.
-
(1998)
Diabetes
, vol.47
, pp. 294-297
-
-
Mizuno, T.1
Kleopoulos, S.2
Bergen, H.3
Roberts, J.4
Priest, C.5
Mobbs, C.6
-
20
-
-
0035950093
-
Intracellular signalling. Key enzyme in leptin-induced anorexia
-
Niswender KD, Morton GJ, Stearns WH, Rhodes CJ, Myers Jr MG, Schwartz MW (2001) Intracellular signalling. Key enzyme in leptin-induced anorexia. Nature 413:794-795.
-
(2001)
Nature
, vol.413
, pp. 794-795
-
-
Niswender, K.D.1
Morton, G.J.2
Stearns, W.H.3
Rhodes, C.J.4
Myers M.G., Jr.5
Schwartz, M.W.6
-
21
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann M, Wilson B, Yang Y, Kerns J, Chen Y, Gantz I, Barsh G (1997) Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278:135-138.
-
(1997)
Science
, vol.278
, pp. 135-138
-
-
Ollmann, M.1
Wilson, B.2
Yang, Y.3
Kerns, J.4
Chen, Y.5
Gantz, I.6
Barsh, G.7
-
22
-
-
0026670206
-
Insulin in the brain: A hormonal regulator of energy balance
-
Schwartz MW, Figlewicz DP, Baskin DG, Woods SC, Porte Jr D (1992) Insulin in the brain: A hormonal regulator of energy balance. Endocr Rev 13:387-414.
-
(1992)
Endocr Rev
, vol.13
, pp. 387-414
-
-
Schwartz, M.W.1
Figlewicz, D.P.2
Baskin, D.G.3
Woods, S.C.4
Porte D., Jr.5
-
23
-
-
0030775971
-
Leptin increases hypothalamic proopiomelanocoritin (POMC) mRNA expression in the rostral arcuate nucleus
-
Schwartz MW, Seeley RJ, Weigle DS, Burn P, Campfield LA, Baskin DG (1997) Leptin increases hypothalamic proopiomelanocoritin (POMC) mRNA expression in the rostral arcuate nucleus. Diabetes 46:2119-2123.
-
(1997)
Diabetes
, vol.46
, pp. 2119-2123
-
-
Schwartz, M.W.1
Seeley, R.J.2
Weigle, D.S.3
Burn, P.4
Campfield, L.A.5
Baskin, D.G.6
-
24
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz MW, Woods SC, Porte DJ, Seeley RJ, Baskin DG (2000) Central nervous system control of food intake. Nature 404:661-671.
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte, D.J.3
Seeley, R.J.4
Baskin, D.G.5
-
25
-
-
0031443366
-
Melanocortin receptors in leptin effects
-
Seeley RJ, Yagaloff KA, Fisher SL, Burn P, Thiele TE, van Dijk D, Baskin DG, Schwartz MW (1997) Melanocortin receptors in leptin effects. Nature 390:349.
-
(1997)
Nature
, vol.390
, pp. 349
-
-
Seeley, R.J.1
Yagaloff, K.A.2
Fisher, S.L.3
Burn, P.4
Thiele, T.E.5
Van Dijk, D.6
Baskin, D.G.7
Schwartz, M.W.8
-
26
-
-
0033971939
-
Targeted deletion of the tub mouse obesity gene reveals that tubby is a loss-of-function mutation
-
Stubdal H, Lynch CA, Moriarty A, Fang Q, Chickering T, Deeds JD, Fairchild-Huntress V, Charlat O, Dunmore JH, Kleyn P, Huszar DK, R (2000) Targeted deletion of the tub mouse obesity gene reveals that tubby is a loss-of-function mutation. Mol Cell Biol 20:878-882.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 878-882
-
-
Stubdal, H.1
Lynch, C.A.2
Moriarty, A.3
Fang, Q.4
Chickering, T.5
Deeds, J.D.6
Fairchild-Huntress, V.7
Charlat, O.8
Dunmore, J.H.9
Kleyn, P.10
Huszar, D.K.11
-
27
-
-
0031914232
-
Central infusion of melanocortin agonist MTII in rats: Assessment of c-Fos expression and taste aversion
-
Thiele T, van DG, Yagaloff K, Fisher S, Schwartz M, Burn P, Seeley R (1998) Central infusion of melanocortin agonist MTII in rats: Assessment of c-Fos expression and taste aversion. Am J Physiol 274:R248-R254.
-
(1998)
Am J Physiol
, vol.274
-
-
Thiele, T.1
Van, D.G.2
Yagaloff, K.3
Fisher, S.4
Schwartz, M.5
Burn, P.6
Seeley, R.7
-
28
-
-
0030729210
-
Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice
-
Thornton JE, Cheung CC, Clifton DK, Steiner RA (1997) Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice. Endocrinology 138:5063-5067.
-
(1997)
Endocrinology
, vol.138
, pp. 5063-5067
-
-
Thornton, J.E.1
Cheung, C.C.2
Clifton, D.K.3
Steiner, R.A.4
-
29
-
-
0022458884
-
Use of a cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology
-
Watson Jr RE, Wiegand SJ, Clough RW, Hoffman GE (1986) Use of a cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides 7:155-159.
-
(1986)
Peptides
, vol.7
, pp. 155-159
-
-
Watson R.E., Jr.1
Wiegand, S.J.2
Clough, R.W.3
Hoffman, G.E.4
-
30
-
-
0016374926
-
Metabolic hormones and regulation of body weight
-
Woods SC, Decke E, Vasselli JR (1974) Metabolic hormones and regulation of body weight. Psychol Rev 81:26-43.
-
(1974)
Psychol Rev
, vol.81
, pp. 26-43
-
-
Woods, S.C.1
Decke, E.2
Vasselli, J.R.3
-
31
-
-
0018621289
-
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons
-
Woods SC, Lotter EC, McKay LD, Porte Jr D (1979) Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons. Nature 282:503-505.
-
(1979)
Nature
, vol.282
, pp. 503-505
-
-
Woods, S.C.1
Lotter, E.C.2
McKay, L.D.3
Porte D., Jr.4
-
32
-
-
0032577376
-
Signals that regulate food intake and energy homeostasis
-
Woods SC, Seeley RJ, Porte DJ, Schwartz MW (1998) Signals that regulate food intake and energy homeostasis. Science 280:1378-1383.
-
(1998)
Science
, vol.280
, pp. 1378-1383
-
-
Woods, S.C.1
Seeley, R.J.2
Porte, D.J.3
Schwartz, M.W.4
-
33
-
-
0032863468
-
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
-
Yaswen L, Diehl N, Brennan MB, Hochgeschwender U (1999) Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Nat Med 5:1066-1070.
-
(1999)
Nat Med
, vol.5
, pp. 1066-1070
-
-
Yaswen, L.1
Diehl, N.2
Brennan, M.B.3
Hochgeschwender, U.4
|