-
1
-
-
84555187749
-
Mammalian target of rapamycin: A signaling kinase for every aspect of cellular life
-
Weichhart, T. (2012) Mammalian target of rapamycin: a signaling kinase for every aspect of cellular life. Methods Mol. Biol. 821, 1-14
-
(2012)
Methods Mol. Biol.
, vol.821
, pp. 1-14
-
-
Weichhart, T.1
-
2
-
-
84877927481
-
MTOR in aging, metabolism, and cancer
-
Cornu, M., Albert, V. and Hall, M.N. (2013) mTOR in aging, metabolism, and cancer. Curr. Opin. Genet. Dev. 23, 53-62
-
(2013)
Curr. Opin. Genet. Dev.
, vol.23
, pp. 53-62
-
-
Cornu, M.1
Albert, V.2
Hall, M.N.3
-
3
-
-
82555164917
-
TOR in the immune system
-
Araki, K., Ellebedy, A.H. and Ahmed, R. (2011) TOR in the immune system. Curr. Opin. Cell Biol. 23, 707-715
-
(2011)
Curr. Opin. Cell Biol.
, vol.23
, pp. 707-715
-
-
Araki, K.1
Ellebedy, A.H.2
Ahmed, R.3
-
4
-
-
65349159281
-
Immunoregulatory functions of mTOR inhibition
-
Thomson, A.W., Turnquist, H.R. and Raimondi, G. (2009) Immunoregulatory functions of mTOR inhibition. Nat. Rev. Immunol. 9, 324-337
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 324-337
-
-
Thomson, A.W.1
Turnquist, H.R.2
Raimondi, G.3
-
5
-
-
65449135649
-
The multiple facets of mTOR in immunity
-
Weichhart, T. and Saemann, M.D. (2009) The multiple facets of mTOR in immunity. Trends Immunol. 30, 218-226
-
(2009)
Trends Immunol.
, vol.30
, pp. 218-226
-
-
Weichhart, T.1
Saemann, M.D.2
-
6
-
-
84859388578
-
Regulation of immune responses by mTOR
-
Powell, J.D., Pollizzi, K.N., Heikamp, E.B. and Horton, M.R. (2012) Regulation of immune responses by mTOR. Annu. Rev. Immunol. 30, 39-68
-
(2012)
Annu. Rev. Immunol.
, vol.30
, pp. 39-68
-
-
Powell, J.D.1
Pollizzi, K.N.2
Heikamp, E.B.3
Horton, M.R.4
-
7
-
-
84860237060
-
Regulation and function of mTOR signalling in T cell fate decisions
-
Chi, H. (2012) Regulation and function of mTOR signalling in T cell fate decisions. Nat. Rev. Immunol. 12, 325-338
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 325-338
-
-
Chi, H.1
-
8
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante, M. and Sabatini, D.M. (2012) mTOR signaling in growth control and disease. Cell 149, 274-293
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
9
-
-
77957870285
-
MTOR mediated anti-cancer drug discovery
-
Liu, Q., Thoreen, C., Wang, J., Sabatini, D. and Gray, N.S. (2009) mTOR mediated anti-cancer drug discovery. Drug Discovery Today: Ther. Strategies 6, 47-55
-
(2009)
Drug Discovery Today: Ther. Strategies
, vol.6
, pp. 47-55
-
-
Liu, Q.1
Thoreen, C.2
Wang, J.3
Sabatini, D.4
Gray, N.S.5
-
10
-
-
54949109311
-
The TSC-mTOR signaling pathway regulates the innate inflammatory response
-
Weichhart, T., Costantino, G., Poglitsch, M., Rosner, M., Zeyda, M., Stuhlmeier, K.M., Kolbe, T., Stulnig, T.M., Horl, W.H., Hengstschlager, M. et al. (2008) The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity 29, 565-577
-
(2008)
Immunity
, vol.29
, pp. 565-577
-
-
Weichhart, T.1
Costantino, G.2
Poglitsch, M.3
Rosner, M.4
Zeyda, M.5
Stuhlmeier, K.M.6
Kolbe, T.7
Stulnig, T.M.8
Horl, W.H.9
Hengstschlager, M.10
-
11
-
-
58149352480
-
Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells
-
Schmitz, F., Heit, A., Dreher, S., Eisenacher, K., Mages, J., Haas, T., Krug, A., Janssen, K.P., Kirschning, C.J. and Wagner, H. (2008) Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells. Eur. J. Immunol. 38, 2981-2992
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 2981-2992
-
-
Schmitz, F.1
Heit, A.2
Dreher, S.3
Eisenacher, K.4
Mages, J.5
Haas, T.6
Krug, A.7
Janssen, K.P.8
Kirschning, C.J.9
Wagner, H.10
-
12
-
-
77953262646
-
The phosphoproteome of Toll-like receptor-activated macrophages
-
Weintz, G., Olsen, J.V., Fruhauf, K., Niedzielska, M., Amit, I., Jantsch, J., Mages, J., Frech, C., Dolken, L., Mann, M. et al. (2010) The phosphoproteome of Toll-like receptor-activated macrophages. Mol. Syst. Biol. 6, 371
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 371
-
-
Weintz, G.1
Olsen, J.V.2
Fruhauf, K.3
Niedzielska, M.4
Amit, I.5
Jantsch, J.6
Mages, J.7
Frech, C.8
Dolken, L.9
Mann, M.10
-
13
-
-
77958126087
-
A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation
-
Haidinger, M., Poglitsch, M., Geyeregger, R., Kasturi, S., Zeyda, M., Zlabinger, G.J., Pulendran, B., Horl, W.H., Saemann, M.D. and Weichhart, T. (2010) A versatile role of mammalian target of rapamycin in human dendritic cell function and differentiation. J. Immunol. 185, 3919-3931
-
(2010)
J. Immunol.
, vol.185
, pp. 3919-3931
-
-
Haidinger, M.1
Poglitsch, M.2
Geyeregger, R.3
Kasturi, S.4
Zeyda, M.5
Zlabinger, G.J.6
Pulendran, B.7
Horl, W.H.8
Saemann, M.D.9
Weichhart, T.10
-
14
-
-
77958470125
-
Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling
-
Sathaliyawala, T., O'Gorman, W.E., Greter, M., Bogunovic, M., Konjufca, V., Hou, Z.E., Nolan, G.P., Miller, M.J., Merad, M. and Reizis, B. (2010) Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling. Immunity 33, 597-606
-
(2010)
Immunity
, vol.33
, pp. 597-606
-
-
Sathaliyawala, T.1
O'Gorman, W.E.2
Greter, M.3
Bogunovic, M.4
Konjufca, V.5
Hou, Z.E.6
Nolan, G.P.7
Miller, M.J.8
Merad, M.9
Reizis, B.10
-
15
-
-
84872300827
-
Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function
-
Kellersch, B. and Brocker, T. (2013) Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function. Blood 121, 298-307
-
(2013)
Blood
, vol.121
, pp. 298-307
-
-
Kellersch, B.1
Brocker, T.2
-
16
-
-
77953643797
-
Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling
-
van de Laar, L., Buitenhuis, M., Wensveen, F.M., Janssen, H.L., Coffer, P.J. and Woltman, A.M. (2010) Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling. J. Immunol. 184, 6600-6611
-
(2010)
J. Immunol.
, vol.184
, pp. 6600-6611
-
-
Van De Laar, L.1
Buitenhuis, M.2
Wensveen, F.M.3
Janssen, H.L.4
Coffer, P.J.5
Woltman, A.M.6
-
17
-
-
84871026677
-
PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function
-
van de Laar, L., van den Bosch, A., Boonstra, A., Binda, R.S., Buitenhuis, M., Janssen, H.L., Coffer, P.J. and Woltman, A.M. (2012) PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function. Blood 120, 4982-4991
-
(2012)
Blood
, vol.120
, pp. 4982-4991
-
-
Van De Laar, L.1
Van Den Bosch, A.2
Boonstra, A.3
Binda, R.S.4
Buitenhuis, M.5
Janssen, H.L.6
Coffer, P.J.7
Woltman, A.M.8
-
18
-
-
34249805413
-
Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance
-
Turnquist, H.R., Raimondi, G., Zahorchak, A.F., Fischer, R.T., Wang, Z. and Thomson, A.W. (2007) Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance. J. Immunol. 178, 7018-7031
-
(2007)
J. Immunol.
, vol.178
, pp. 7018-7031
-
-
Turnquist, H.R.1
Raimondi, G.2
Zahorchak, A.F.3
Fischer, R.T.4
Wang, Z.5
Thomson, A.W.6
-
19
-
-
0036707521
-
PI3K-mediated negative feedback regulation of IL-12 production in DCs
-
Fukao, T., Tanabe, M., Terauchi, Y., Ota, T., Matsuda, S., Asano, T., Kadowaki, T., Takeuchi, T. and Koyasu, S. (2002) PI3K-mediated negative feedback regulation of IL-12 production in DCs. Nat. Immunol. 3, 875-881
-
(2002)
Nat. Immunol.
, vol.3
, pp. 875-881
-
-
Fukao, T.1
Tanabe, M.2
Terauchi, Y.3
Ota, T.4
Matsuda, S.5
Asano, T.6
Kadowaki, T.7
Takeuchi, T.8
Koyasu, S.9
-
20
-
-
50949130076
-
Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells
-
Ohtani, M., Nagai, S., Kondo, S., Mizuno, S., Nakamura, K., Tanabe, M., Takeuchi, T., Matsuda, S. and Koyasu, S. (2008) Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide- induced interleukin-12 production in dendritic cells. Blood 112, 635-643
-
(2008)
Blood
, vol.112
, pp. 635-643
-
-
Ohtani, M.1
Nagai, S.2
Kondo, S.3
Mizuno, S.4
Nakamura, K.5
Tanabe, M.6
Takeuchi, T.7
Matsuda, S.8
Koyasu, S.9
-
21
-
-
79955973785
-
Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells
-
Weichhart, T., Haidinger, M., Katholnig, K., Kopecky, C., Poglitsch, M., Lassnig, C., Rosner, M., Zlabinger, G.J., Hengstschlager, M., Muller, M. et al. (2011) Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells. Blood 117, 4273-4283
-
(2011)
Blood
, vol.117
, pp. 4273-4283
-
-
Weichhart, T.1
Haidinger, M.2
Katholnig, K.3
Kopecky, C.4
Poglitsch, M.5
Lassnig, C.6
Rosner, M.7
Zlabinger, G.J.8
Hengstschlager, M.9
Muller, M.10
-
22
-
-
77954748989
-
MTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS
-
Turnquist, H.R., Cardinal, J., Macedo, C., Rosborough, B.R., Sumpter, T.L., Geller, D.A., Metes, D. and Thomson, A.W. (2010) mTOR and GSK-3 shape the CD4+ T-cell stimulatory and differentiation capacity of myeloid DCs after exposure to LPS. Blood 115, 4758-4769
-
(2010)
Blood
, vol.115
, pp. 4758-4769
-
-
Turnquist, H.R.1
Cardinal, J.2
Macedo, C.3
Rosborough, B.R.4
Sumpter, T.L.5
Geller, D.A.6
Metes, D.7
Thomson, A.W.8
-
23
-
-
79958806173
-
MTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment
-
Jiang, Q., Weiss, J.M., Back, T., Chan, T., Ortaldo, J.R., Guichard, S. and Wiltrout, R.H. (2011) mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment. Cancer Res. 71, 4074-4084
-
(2011)
Cancer Res.
, vol.71
, pp. 4074-4084
-
-
Jiang, Q.1
Weiss, J.M.2
Back, T.3
Chan, T.4
Ortaldo, J.R.5
Guichard, S.6
Wiltrout, R.H.7
-
24
-
-
84863232885
-
Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway
-
Chen, W., Ma, T., Shen, X.N., Xia, X.F., Xu, G.D., Bai, X.L. and Liang, T.B. (2012) Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway. Cancer Res. 72, 1363-1372
-
(2012)
Cancer Res.
, vol.72
, pp. 1363-1372
-
-
Chen, W.1
Ma, T.2
Shen, X.N.3
Xia, X.F.4
Xu, G.D.5
Bai, X.L.6
Liang, T.B.7
-
25
-
-
84860553050
-
MTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection
-
Cheekatla, S.S., Aggarwal, A. and Naik, S. (2012) mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection. Med. Microbiol. Immunol. 201, 37-46
-
(2012)
Med. Microbiol. Immunol.
, vol.201
, pp. 37-46
-
-
Cheekatla, S.S.1
Aggarwal, A.2
Naik, S.3
-
26
-
-
0036153880
-
Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: Implications for rheumatoid arthritis
-
Foey, A., Green, P., Foxwell, B., Feldmann, M. and Brennan, F. (2002) Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis. Arthritis Res. 4, 64-70
-
(2002)
Arthritis Res.
, vol.4
, pp. 64-70
-
-
Foey, A.1
Green, P.2
Foxwell, B.3
Feldmann, M.4
Brennan, F.5
-
27
-
-
84861157347
-
Cutting Edge: MTORC1 in intestinal CD11c+ CD11b+ dendritic cells regulates intestinal homeostasis by promoting IL-10 production
-
Ohtani, M., Hoshii, T., Fujii, H., Koyasu, S., Hirao, A. and Matsuda, S. (2012) Cutting Edge: mTORC1 in intestinal CD11c+ CD11b+ dendritic cells regulates intestinal homeostasis by promoting IL-10 production. J. Immunol. 188, 4736-4740
-
(2012)
J. Immunol.
, vol.188
, pp. 4736-4740
-
-
Ohtani, M.1
Hoshii, T.2
Fujii, H.3
Koyasu, S.4
Hirao, A.5
Matsuda, S.6
-
28
-
-
67349217332
-
Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-α expression in macrophages by reducing IL-10 expression
-
Baker, A.K., Wang, R., Mackman, N. and Luyendyk, J.P. (2009) Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-α expression in macrophages by reducing IL-10 expression. Mol. Immunol. 46, 2249-2255
-
(2009)
Mol. Immunol.
, vol.46
, pp. 2249-2255
-
-
Baker, A.K.1
Wang, R.2
Mackman, N.3
Luyendyk, J.P.4
-
29
-
-
78650509768
-
Secretory mediators regulate Nod2-induced tolerance in human macrophages
-
Hedl, M. and Abraham, C. (2011) Secretory mediators regulate Nod2-induced tolerance in human macrophages. Gastroenterology 140, 231-241
-
(2011)
Gastroenterology
, vol.140
, pp. 231-241
-
-
Hedl, M.1
Abraham, C.2
-
30
-
-
77954470662
-
Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema
-
Yoshida, T., Mett, I., Bhunia, A.K., Bowman, J., Perez, M., Zhang, L., Gandjeva, A., Zhen, L., Chukwueke, U., Mao, T. et al. (2010) Rtp801, a suppressor of mTOR signaling, is an essential mediator of cigarette smoke-induced pulmonary injury and emphysema. Nat. Med. 16, 767-773
-
(2010)
Nat. Med.
, vol.16
, pp. 767-773
-
-
Yoshida, T.1
Mett, I.2
Bhunia, A.K.3
Bowman, J.4
Perez, M.5
Zhang, L.6
Gandjeva, A.7
Zhen, L.8
Chukwueke, U.9
Mao, T.10
-
31
-
-
82755189234
-
Mammalian target of rapamycin inhibition in macrophages of asymptomatic HIV+ persons reverses the decrease in TLR-4-mediated TNF-α release through prolongation of MAPK pathway activation
-
Li, X., Han, X., Llano, J., Bole, M., Zhou, X., Swan, K., Anandaiah, A., Nelson, B., Patel, N.R., Reinach, P.S. et al. (2011) Mammalian target of rapamycin inhibition in macrophages of asymptomatic HIV+ persons reverses the decrease in TLR-4-mediated TNF-α release through prolongation of MAPK pathway activation. J. Immunol. 187, 6052-6058
-
(2011)
J. Immunol.
, vol.187
, pp. 6052-6058
-
-
Li, X.1
Han, X.2
Llano, J.3
Bole, M.4
Zhou, X.5
Swan, K.6
Anandaiah, A.7
Nelson, B.8
Patel, N.R.9
Reinach, P.S.10
-
32
-
-
77953272740
-
Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses
-
Blanchet, F.P., Moris, A., Nikolic, D.S., Lehmann, M., Cardinaud, S., Stalder, R., Garcia, E., Dinkins, C., Leuba, F., Wu, L. et al. (2010) Human immunodeficiency virus-1 inhibition of immunoamphisomes in dendritic cells impairs early innate and adaptive immune responses. Immunity 32, 654-669
-
(2010)
Immunity
, vol.32
, pp. 654-669
-
-
Blanchet, F.P.1
Moris, A.2
Nikolic, D.S.3
Lehmann, M.4
Cardinaud, S.5
Stalder, R.6
Garcia, E.7
Dinkins, C.8
Leuba, F.9
Wu, L.10
-
33
-
-
84455161606
-
Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1
-
Brown, J., Wang, H., Suttles, J., Graves, D.T. and Martin, M. (2011) Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1. J. Biol. Chem. 286, 44295-44305
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 44295-44305
-
-
Brown, J.1
Wang, H.2
Suttles, J.3
Graves, D.T.4
Martin, M.5
-
34
-
-
78650266432
-
FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages
-
Fan, W., Morinaga, H., Kim, J.J., Bae, E., Spann, N.J., Heinz, S., Glass, C.K. and Olefsky, J.M. (2010) FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages. EMBO J. 29, 4223-4236
-
(2010)
EMBO J.
, vol.29
, pp. 4223-4236
-
-
Fan, W.1
Morinaga, H.2
Kim, J.J.3
Bae, E.4
Spann, N.J.5
Heinz, S.6
Glass, C.K.7
Olefsky, J.M.8
-
35
-
-
84860333507
-
The role of tuberous sclerosis complex 1 in regulating innate immunity
-
Pan, H., O'Brien, T.F., Zhang, P. and Zhong, X.P. (2012) The role of tuberous sclerosis complex 1 in regulating innate immunity. J. Immunol. 188, 3658-3666
-
(2012)
J. Immunol.
, vol.188
, pp. 3658-3666
-
-
Pan, H.1
O'Brien, T.F.2
Zhang, P.3
Zhong, X.P.4
-
36
-
-
44949215822
-
The TSC1-TSC2 complex is required for proper activation of mTOR complex 2
-
Huang, J., Dibble, C.C., Matsuzaki, M. and Manning, B.D. (2008) The TSC1-TSC2 complex is required for proper activation of mTOR complex 2. Mol. Cell. Biol. 28, 4104-4115
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 4104-4115
-
-
Huang, J.1
Dibble, C.C.2
Matsuzaki, M.3
Manning, B.D.4
-
37
-
-
78649836813
-
Comparative transcriptional and phenotypic peripheral blood analysis of kidney recipients under cyclosporin A or sirolimus monotherapy
-
Brouard, S., Puig-Pey, I., Lozano, J.J., Pallier, A., Braud, C., Giral, M., Guillet, M., Londoño, M.C., Oppenheimer, F., Campistol, J.M. et al. (2010) Comparative transcriptional and phenotypic peripheral blood analysis of kidney recipients under cyclosporin A or sirolimus monotherapy. Am. J. Transplant. 10, 2604-2614
-
(2010)
Am. J. Transplant.
, vol.10
, pp. 2604-2614
-
-
Brouard, S.1
Puig-Pey, I.2
Lozano, J.J.3
Pallier, A.4
Braud, C.5
Giral, M.6
Guillet, M.7
Londoño, M.C.8
Oppenheimer, F.9
Campistol, J.M.10
-
38
-
-
72449147738
-
The multifunctional role of mTOR in innate immunity: Implications for transplant immunity
-
Saemann, M.D., Haidinger, M., Hecking, M., Horl, W.H. and Weichhart, T. (2009) The multifunctional role of mTOR in innate immunity: implications for transplant immunity. Am. J. Transplant. 9, 2655-2661
-
(2009)
Am. J. Transplant.
, vol.9
, pp. 2655-2661
-
-
Saemann, M.D.1
Haidinger, M.2
Hecking, M.3
Horl, W.H.4
Weichhart, T.5
-
39
-
-
84872050913
-
Profiling sirolimus-induced inflammatory syndrome: A prospective tricentric observational study
-
Buron, F., Malvezzi, P., Villar, E., Chauvet, C., Janbon, B., Denis, L., Brunet, M., Daoud, S., Cahen, R., Pouteil-Noble, C. et al. (2013) Profiling sirolimus-induced inflammatory syndrome: a prospective tricentric observational study. PLoS ONE 8, e53078
-
(2013)
PLoS ONE
, vol.8
-
-
Buron, F.1
Malvezzi, P.2
Villar, E.3
Chauvet, C.4
Janbon, B.5
Denis, L.6
Brunet, M.7
Daoud, S.8
Cahen, R.9
Pouteil-Noble, C.10
-
40
-
-
84865130666
-
The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response
-
Kirsch, A.H., Riegelbauer, V., Tagwerker, A., Rudnicki, M., Rosenkranz, A.R. and Eller, K. (2012) The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response. Am. J. Physiol. Renal Physiol. 303, F569-F575
-
(2012)
Am. J. Physiol. Renal Physiol.
, vol.303
-
-
Kirsch, A.H.1
Riegelbauer, V.2
Tagwerker, A.3
Rudnicki, M.4
Rosenkranz, A.R.5
Eller, K.6
-
41
-
-
84861818332
-
CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages
-
Poglitsch, M., Weichhart, T., Hecking, M., Werzowa, J., Katholnig, K., Antlanger, M., Krmpotic, A., Jonjic, S., Horl, W.H., Zlabinger, G.J. et al. (2012) CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages. Am. J. Transplant. 12, 1458-1468
-
(2012)
Am. J. Transplant.
, vol.12
, pp. 1458-1468
-
-
Poglitsch, M.1
Weichhart, T.2
Hecking, M.3
Werzowa, J.4
Katholnig, K.5
Antlanger, M.6
Krmpotic, A.7
Jonjic, S.8
Horl, W.H.9
Zlabinger, G.J.10
-
42
-
-
40949116686
-
The TORrid affairs of viruses: Effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway
-
Buchkovich, N.J., Yu, Y., Zampieri, C.A. and Alwine, J.C. (2008) The TORrid affairs of viruses: effects of mammalian DNA viruses on the PI3K-Akt-mTOR signalling pathway. Nat. Rev. Microbiol. 6, 266-275
-
(2008)
Nat. Rev. Microbiol.
, vol.6
, pp. 266-275
-
-
Buchkovich, N.J.1
Yu, Y.2
Zampieri, C.A.3
Alwine, J.C.4
-
43
-
-
0346103719
-
Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis
-
Williams, D.L., Li, C., Ha, T., Ozment-Skelton, T., Kalbfleisch, J.H., Preiszner, J., Brooks, L., Breuel, K. and Schweitzer, J.B. (2004) Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J. Immunol. 172, 449-456
-
(2004)
J. Immunol.
, vol.172
, pp. 449-456
-
-
Williams, D.L.1
Li, C.2
Ha, T.3
Ozment-Skelton, T.4
Kalbfleisch, J.H.5
Preiszner, J.6
Brooks, L.7
Breuel, K.8
Schweitzer, J.B.9
-
44
-
-
0038446051
-
Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide
-
Martin, M., Schifferle, R.E., Cuesta, N., Vogel, S.N., Katz, J. and Michalek, S.M. (2003) Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide. J. Immunol. 171, 717-725
-
(2003)
J. Immunol.
, vol.171
, pp. 717-725
-
-
Martin, M.1
Schifferle, R.E.2
Cuesta, N.3
Vogel, S.N.4
Katz, J.5
Michalek, S.M.6
-
45
-
-
84873560535
-
P38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin
-
Katholnig, K., Kaltenecker, C.C., Hayakawa, H., Rosner, M., Lassnig, C., Zlabinger, G.J., Gaestel, M., Muller, M., Hengstschlager, M., Horl, W.H. et al. (2013) p38α senses environmental stress to control innate immune responses via mechanistic target of rapamycin. J. Immunol. 190, 1519-1527
-
(2013)
J. Immunol.
, vol.190
, pp. 1519-1527
-
-
Katholnig, K.1
Kaltenecker, C.C.2
Hayakawa, H.3
Rosner, M.4
Lassnig, C.5
Zlabinger, G.J.6
Gaestel, M.7
Muller, M.8
Hengstschlager, M.9
Horl, W.H.10
-
46
-
-
79957553362
-
Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: Implications for NO synthase 2 expression
-
Lopez-Pelaez, M., Soria-Castro, I., Bosca, L., Fernandez, M. and Alemany, S. (2011) Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: implications for NO synthase 2 expression. Eur. J. Immunol. 41, 1733-1741
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 1733-1741
-
-
Lopez-Pelaez, M.1
Soria-Castro, I.2
Bosca, L.3
Fernandez, M.4
Alemany, S.5
-
47
-
-
84864767892
-
Cot/tpl2-MKK1/2-Erk1/2 controls mTORC1-mediated mRNA translation in Toll-like receptor-activated macrophages
-
Lopez-Pelaez, M., Fumagalli, S., Sanz, C., Herrero, C., Guerra, S., Fernandez, M. and Alemany, S. (2012) Cot/tpl2-MKK1/2-Erk1/2 controls mTORC1-mediated mRNA translation in Toll-like receptor-activated macrophages. Mol. Biol. Cell 23, 2982-2992
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 2982-2992
-
-
Lopez-Pelaez, M.1
Fumagalli, S.2
Sanz, C.3
Herrero, C.4
Guerra, S.5
Fernandez, M.6
Alemany, S.7
-
48
-
-
41149133368
-
Translational control of the innate immune response through IRF-7
-
Colina, R., Costa-Mattioli, M., Dowling, R.J., Jaramillo, M., Tai, L.H., Breitbach, C.J., Martineau, Y., Larsson, O., Rong, L., Svitkin, Y.V. et al. (2008) Translational control of the innate immune response through IRF-7. Nature 452, 323-328
-
(2008)
Nature
, vol.452
, pp. 323-328
-
-
Colina, R.1
Costa-Mattioli, M.2
Dowling, R.J.3
Jaramillo, M.4
Tai, L.H.5
Breitbach, C.J.6
Martineau, Y.7
Larsson, O.8
Rong, L.9
Svitkin, Y.V.10
-
49
-
-
79955054747
-
Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection
-
Jaramillo, M., Gomez, M.A., Larsson, O., Shio, M.T., Topisirovic, I., Contreras, I., Luxenburg, R., Rosenfeld, A., Colina, R., McMaster, R.W. et al. (2011) Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection. Cell Host Microbe 9, 331-341
-
(2011)
Cell Host Microbe
, vol.9
, pp. 331-341
-
-
Jaramillo, M.1
Gomez, M.A.2
Larsson, O.3
Shio, M.T.4
Topisirovic, I.5
Contreras, I.6
Luxenburg, R.7
Rosenfeld, A.8
Colina, R.9
McMaster, R.W.10
-
50
-
-
62049084947
-
Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells
-
Jagannath, C., Lindsey, D.R., Dhandayuthapani, S., Xu, Y., Hunter, Jr, R.L. and Eissa, N.T. (2009) Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. Nat. Med. 15, 267-276
-
(2009)
Nat. Med.
, vol.15
, pp. 267-276
-
-
Jagannath, C.1
Lindsey, D.R.2
Dhandayuthapani, S.3
Xu, Y.4
Hunter Jr., R.L.5
Eissa, N.T.6
-
51
-
-
84865435212
-
Inhibition of mechanistic target of rapamycin promotes dendritic cell activation and enhances therapeutic autologous vaccination in mice
-
Amiel, E., Everts, B., Freitas, T.C., King, I.L., Curtis, J.D., Pearce, E.L. and Pearce, E.J. (2012) Inhibition of mechanistic target of rapamycin promotes dendritic cell activation and enhances therapeutic autologous vaccination in mice. J. Immunol 189, 2151-2158
-
(2012)
J. Immunol
, vol.189
, pp. 2151-2158
-
-
Amiel, E.1
Everts, B.2
Freitas, T.C.3
King, I.L.4
Curtis, J.D.5
Pearce, E.L.6
Pearce, E.J.7
|