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Volumn 188, Issue 10, 2012, Pages 4736-4740

Cutting edge: mTORC1 in intestinal CD11c +CD11b + dendritic cells regulates intestinal homeostasis by promoting IL-10 production

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 10; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PROTEIN S6;

EID: 84861157347     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200069     Document Type: Article
Times cited : (67)

References (22)
  • 1
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • DOI 10.1016/j.cell.2006.01.016, PII S0092867406001085
    • Wullschleger, S., R. Loewith, and M. N. Hall. 2006. TOR signaling in growth and metabolism. Cell 124: 471-484. (Pubitemid 43199434)
    • (2006) Cell , vol.124 , Issue.3 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3
  • 2
    • 34547907805 scopus 로고    scopus 로고
    • Expanding mTOR signaling
    • DOI 10.1038/cr.2007.64, PII CR200764
    • Yang, Q., and K. L. Guan. 2007. Expanding mTOR signaling. Cell Res. 17: 666-681. (Pubitemid 47255937)
    • (2007) Cell Research , vol.17 , Issue.8 , pp. 666-681
    • Yang, Q.1    Guan, K.-L.2
  • 3
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • DOI 10.1126/science.1106148
    • Sarbassov, D. D., D. A. Guertin, S. M. Ali, and D. M. Sabatini. 2005. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307: 1098-1101. (Pubitemid 40262113)
    • (2005) Science , vol.307 , Issue.5712 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 5
    • 50949130076 scopus 로고    scopus 로고
    • Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells
    • Ohtani, M., S. Nagai, S. Kondo, S. Mizuno, K. Nakamura, M. Tanabe, T. Takeuchi, S. Matsuda, and S. Koyasu. 2008. Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells. Blood 112: 635-643.
    • (2008) Blood , vol.112 , pp. 635-643
    • Ohtani, M.1    Nagai, S.2    Kondo, S.3    Mizuno, S.4    Nakamura, K.5    Tanabe, M.6    Takeuchi, T.7    Matsuda, S.8    Koyasu, S.9
  • 8
    • 77953643797 scopus 로고    scopus 로고
    • Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling
    • van de Laar, L., M. Buitenhuis, F. M. Wensveen, H. L. A. Janssen, P. J. Coffer, and A. M. Woltman. 2010. Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling. J. Immunol. 184: 6600-6611.
    • (2010) J. Immunol. , vol.184 , pp. 6600-6611
    • Van De Laar, L.1    Buitenhuis, M.2    Wensveen, F.M.3    Janssen, H.L.A.4    Coffer, P.J.5    Woltman, A.M.6
  • 11
    • 70350464351 scopus 로고    scopus 로고
    • Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis
    • Murai, M., O. Turovskaya, G. Kim, R. Madan, C. L. Karp, H. Cheroutre, and M. Kronenberg. 2009. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat. Immunol. 10: 1178-1184.
    • (2009) Nat. Immunol. , vol.10 , pp. 1178-1184
    • Murai, M.1    Turovskaya, O.2    Kim, G.3    Madan, R.4    Karp, C.L.5    Cheroutre, H.6    Kronenberg, M.7
  • 12
    • 70350545722 scopus 로고    scopus 로고
    • Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1
    • Dibble, C. C., J. M. Asara, and B. D. Manning. 2009. Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1. Mol. Cell. Biol. 29: 5657-5670.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 5657-5670
    • Dibble, C.C.1    Asara, J.M.2    Manning, B.D.3
  • 13
    • 52549127241 scopus 로고    scopus 로고
    • Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
    • Cao, W., S. Manicassamy, H. Tang, S. P. Kasturi, A. Pirani, N. Murthy, and B. Pulendran. 2008. Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. Nat. Immunol. 9: 1157-1164.
    • (2008) Nat. Immunol. , vol.9 , pp. 1157-1164
    • Cao, W.1    Manicassamy, S.2    Tang, H.3    Kasturi, S.P.4    Pirani, A.5    Murthy, N.6    Pulendran, B.7
  • 14
    • 34548764423 scopus 로고    scopus 로고
    • Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
    • DOI 10.1038/ni1511, PII NI1511
    • Denning, T. L., Y. C. Wang, S. R. Patel, I. R. Williams, and B. Pulendran. 2007. Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nat. Immunol. 8: 1086-1094. (Pubitemid 47423756)
    • (2007) Nature Immunology , vol.8 , Issue.10 , pp. 1086-1094
    • Denning, T.L.1    Wang, Y.-C.2    Patel, S.R.3    Williams, I.R.4    Pulendran, B.5
  • 16
    • 0029086123 scopus 로고
    • Interleukin-10 differentially regulates B7-1 (CD80) and B7-2 (CD86) expression on human peripheral blood dendritic cells
    • Buelens, C., F. Willems, A. Delvaux, G. Piérard, J. P. Delville, T. Velu, and M. Goldman. 1995. Interleukin-10 differentially regulates B7-1 (CD80) and B7-2 (CD86) expression on human peripheral blood dendritic cells. Eur. J. Immunol. 25: 2668-2672.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 2668-2672
    • Buelens, C.1    Willems, F.2    Delvaux, A.3    Piérard, G.4    Delville, J.P.5    Velu, T.6    Goldman, M.7
  • 17
  • 18
    • 34447275920 scopus 로고    scopus 로고
    • - dendritic cells in the spleen
    • DOI 10.1084/jem.20062648
    • Caton, M. L., M. R. Smith-Raska, and B. Reizis. 2007. Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen. J. Exp. Med. 204: 1653-1664. (Pubitemid 47048031)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.7 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 19
    • 33845709678 scopus 로고    scopus 로고
    • An essential role for Akt1 in dendritic cell function and tumor immunotherapy
    • DOI 10.1038/nbt1262, PII NBT1262
    • Park, D., N. Lapteva, M. Seethammagari, K. M. Slawin, and D. M. Spencer. 2006. An essential role for Akt1 in dendritic cell function and tumor immunotherapy. Nat. Biotechnol. 24: 1581-1590. (Pubitemid 44967484)
    • (2006) Nature Biotechnology , vol.24 , Issue.12 , pp. 1581-1590
    • Park, D.1    Lapteva, N.2    Seethammagari, M.3    Slawin, K.M.4    Spencer, D.M.5
  • 20
    • 0038036797 scopus 로고    scopus 로고
    • Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
    • DOI 10.1182/blood-2002-11-3370
    • Hackstein, H., T. Taner, A. F. Zahorchak, A. E. Morelli, A. J. Logar, A. Gessner, and A. W. Thomson. 2003. Rapamycin inhibits IL-4 - induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. Blood 101: 4457-4463. (Pubitemid 36857814)
    • (2003) Blood , vol.101 , Issue.11 , pp. 4457-4463
    • Hackstein, H.1    Taner, T.2    Zahorchak, A.F.3    Morelli, A.E.4    Logar, A.J.5    Gessner, A.6    Thomson, A.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.