Controlled insertional mutagenesis using a LINE-1 (ORFeus) gene-trap mouse model

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 29, 2013, Pages

  O'Donnell, Kathryn A ^a   An, Wenfeng ^a   Schrum, Christina T ^a   Wheelan, Sarah J ^a   Boeke, Jef D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

L1 retrotransposon; Mus Musculus; Tet Promoter; White Spotted Phenotype

Indexed keywords

DNA; DOXYCYCLINE; TETRACYCLINE; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CAPILLARY PROLIFERATION; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE CASSETTE; GENE CONTROL; GENE EXPRESSION; GENE FREQUENCY; GENE INDUCTION; GENOTYPE; IN VIVO STUDY; INSERTIONAL MUTAGENESIS; INVERSE POLYMERASE CHAIN REACTION; MELANOCYTE; MOUSE; MUTAGENESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RETROPOSON; TRANSGENE; TRANSPOSON;

L1 RETROTRANSPOSON; MUS MUSCULUS; TET-PROMOTER; WHITE-SPOTTED PHENOTYPE;

ANIMALS; BLOTTING, NORTHERN; DNA PRIMERS; FLUORESCENT ANTIBODY TECHNIQUE; GENOTYPE; HELA CELLS; HUMANS; LONG INTERSPERSED NUCLEOTIDE ELEMENTS; MELANOCYTES; MICE; MICE, TRANSGENIC; MUTAGENESIS, INSERTIONAL; POLYMERASE CHAIN REACTION; REAL-TIME POLYMERASE CHAIN REACTION; RETROELEMENTS; TETRACYCLINE;

EID: 84880376915     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1302504110     Document Type: Article

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