Tankyrases as drug targets

FEBS Journal

Volumn 280, Issue 15, 2013, Pages 3576-3593

  Lehtiö, Lari ^a   Chi, Nai Wen ^b   Krauss, Stefan ^c  

^a UNIVERSITY OF OULU   (Finland)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

cancer; diphtheria toxin like ADP ribosyltransferase (ARTD); drug discovery; mitosis; poly(ADP ribose) polymerase (PARP); tankyrase; telomere; vesicle trafficking; Wnt signalling

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 3 AMINOBENZAMIDE; 3 AMINOBENZAMIDINE; ANKYRIN; BETA CATENIN; FLAVONE; G 007 LK; G 007LK; GLUCOSE TRANSPORTER 4; GLYCOSYLTRANSFERASE INHIBITOR; IWR 1; JW 55; JW 74; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 2; OXAZOLIDINONE; PHENANTHRIDINONE; PROTEASOME; QUINAZOLINONE DERIVATIVE; SMALL INTERFERING RNA; TANKYRASE; TANKYRASE 1; TANKYRASE 2; TANKYRASE INHIBITOR; TIQ A; UNCLASSIFIED DRUG; UNINDEXED DRUG; WIKI 4; XAV 939;

CELL VACUOLE; CELLULAR DISTRIBUTION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME STRUCTURE; HUMAN; IC 50; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; REVIEW; TELOMERE;

CANCER; DIPHTHERIA TOXIN-LIKE ADP-RIBOSYLTRANSFERASE (ARTD); DRUG DISCOVERY; MITOSIS; POLY(ADP-RIBOSE) POLYMERASE (PARP); TANKYRASE; TELOMERE; VESICLE TRAFFICKING; WNT SIGNALLING;

ADENOSINE DIPHOSPHATE RIBOSE; AMINO ACID MOTIFS; ANIMALS; ANTINEOPLASTIC AGENTS; CATALYTIC DOMAIN; HUMANS; MITOSIS; MODELS, MOLECULAR; NEOPLASMS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; TANKYRASES; TELOMERE HOMEOSTASIS;

EID: 84880330905     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12320     Document Type: Review

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