Tankyrase 1 regulates centrosome function by controlling CPAP stability

EMBO Reports

Volumn 13, Issue 8, 2012, Pages 724-732

  Kim, Mi Kyung ^a   Dudognon, Charles ^a   Smith, Susan ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

centrosome; CPAP; tankyrase 1

Indexed keywords

CENTROSOMAL P4 1 ASSOCIATED PROTEIN; GREEN FLUORESCENT PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEASOME; PROTEIN; SHORT HAIRPIN RNA; TANKYRASE; TANKYRASE 1; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G1 PHASE; CENTRIOLE; CENTROSOME; CONTROLLED STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL LINE; CENTROSOME; G1 PHASE; HUMANS; MICROTUBULE-ASSOCIATED PROTEINS; MOLECULAR SEQUENCE DATA; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; PROTEIN STABILITY; PROTEOLYSIS; TANKYRASES; UBIQUITINATION;

EID: 84864876510     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2012.86     Document Type: Article

References (27)

1. Azimzadeh J, Bornens M (2007) Structure and duplication of the centrosome. J Cell Sci 120: 2139-2142
2. Nigg EA, Stearns T (2011) The centrosome cycle: centriole biogenesis, duplication and inherent asymmetries. Nat Cell Biol 13: 1154-1160
3. Strnad P, Gonczy P (2008) Mechanisms of procentriole formation. Trends Cell Biol 18: 389-396
4. Leidel S, Gonczy P (2003) SAS-4 is essential for centrosome duplication in C. elegans and is recruited to daughter centrioles once per cell cycle. Dev Cell 4: 431-439
5. Pelletier L, O'Toole E, Schwager A, Hyman AA, Muller-Reichert T (2006) Centriole assembly in Caenorhabditis elegans. Nature 444: 619-623
6. Hsu WB, Hung LY, Tang CJ, Su CL, Chang Y, Tang TK (2008) Functional characterization of the microtubule-binding and-destabilizing domains of CPAP and d-SAS-4. Exp Cell Res 314: 2591-2602
7. Hung LY, Tang CJ, Tang TK (2000) Protein 4.1 R-135 interacts with a novel centrosomal protein (CPAP) which is associated with the gamma-tubulin complex. Mol Cell Biol 20: 7813-7825
8. Kleylein-Sohn J, Westendorf J, Le Clech M, Habedanck R, Stierhof YD, Nigg EA (2007) Plk4-induced centriole biogenesis in human cells. Dev Cell 13: 190-202
9. Kohlmaier G, Loncarek J, Meng X, McEwen BF, Mogensen MM, Spektor A, Dynlacht BD, Khodjakov A, Gonczy P (2009) Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP. Curr Biol 19: 1012-1018
10. Schmidt TI, Kleylein-Sohn J, Westendorf J, Le Clech M, Lavoie SB, Stierhof YD, Nigg EA (2009) Control of centriole length by CPAP and CP110. Curr Biol 19: 1005-1011
11. Tang CJ, Fu RH, Wu KS, Hsu WB, Tang TK (2009) CPAP is a cell-cycle regulated protein that controls centriole length. Nat Cell Biol 11: 825-831
12. Bettencourt-Dias M, Hildebrandt F, Pellman D, Woods G, Godinho SA (2011) Centrosomes and cilia in human disease. Trends Genet 27: 307-315
13. Bond J et al (2005) A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size. Nat Genet 37: 353-355
14. Thornton GK, Woods CG (2009) Primary microcephaly: do all roads lead to Rome? Trends Genet 25: 501-510
15. Hsiao SJ, Smith S (2008) Tankyrase function at telomeres, spindle poles, and beyond. Biochimie 90: 83-92
16. Smith S, Giriat I, Schmitt A, de Lange T (1998) Tankyrase, a poly (ADP-ribose) polymerase at human telomeres (see comments). Science 282: 1484-1487
17. Chang W, Dynek JN, Smith S (2003) TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres. Genes Dev 17: 1328-1333
18. Huang SM et al (2009) Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature 461: 614-620
19. Guettler S, LaRose J, Petsalaki E, Gish G, Scotter A, Pawson T, Rottapel R, Sicheri F (2011) Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease. Cell 147: 1340-1354
20. Sbodio JI, Chi NW (2002) Identification of a tankyrase-binding motif shared by IRAP, TAB182, and human TRF1 but not mouse TRF1. NuMA contains this RXXPDG motif and is a novel tankyrase partner. J Biol Chem 277: 31887-31892
21. Cook BD, Dynek JN, Chang W, Shostak G, Smith S (2002) Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol Cell Biol 22: 332-342
22. Tsang WY, Spektor A, Vijayakumar S, Bista BR, Li J, Sanchez I, Duensing S, Dynlacht BD (2009) Cep76, a centrosomal protein that specifically restrains centriole reduplication. Dev Cell 16: 649-660
23. Guarguaglini G, Duncan PI, Stierhof YD, Holmstrom T, Duensing S, Nigg EA (2005) The forkhead-associated domain protein Cep170 interacts with Polo-like kinase 1 and serves as a marker for mature centrioles. Mol Biol Cell 16: 1095-1107
24. Kanai M, Uchida M, Hanai S, Uematsu N, Uchida K, Miwa M (2000) Poly(ADP-ribose) polymerase localizes to the centrosomes and chromosomes. Biochem Biophys Res Commun 278: 385-389
25. Augustin A et al (2003) PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression. J Cell Sci 116: 1551-1562
26. Kanai M, Tong WM, Sugihara E, Wang ZQ, Fukasawa K, Miwa M (2003) Involvement of poly(ADP-Ribose) polymerase 1 and poly(ADPRibosyl) ation in regulation of centrosome function. Mol Cell Biol 23: 2451-2462
27. Hsiao SJ, Smith S (2009) Sister telomeres rendered dysfunctional by persistent cohesion are fused by NHEJ. J Cell Biol 184: 515-526