Homogeneous screening assay for human tankyrase

Journal of Biomolecular Screening

Volumn 17, Issue 5, 2012, Pages 593-604

  Narwal, Mohit ^a   Fallarero, Adyary ^a   Vuorela, Pia ^a   Lehtiö, Lari ^a  

^a ÅBO AKADEMI UNIVERSITY   (Finland)

Author keywords

enzyme; flavones; high throughput assay; NAD+; PARP; poly(ADP ribose) polymerase; screening; tankyrase

Indexed keywords

APIGENIN; ENZYME INHIBITOR; FLAVONE; FLAVONE DERIVATIVE; GALLIC ACID ISOPROPYL ESTER; LUTEOLIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 2; TANKYRASE; TANKYRASE I; TANKYRASE INHIBITOR; UNCLASSIFIED DRUG; WNT PROTEIN;

ACCURACY; ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; CATALYST; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME MODIFICATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; FLUORESCENCE; HIGH THROUGHPUT SCREENING; HUMAN; IC 50; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROCESSING; REPRODUCIBILITY; SIGNAL TRANSDUCTION; TELOMERE HOMEOSTASIS;

ENZYME ACTIVATION; ENZYME ASSAYS; ENZYME INHIBITORS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INHIBITORY CONCENTRATION 50; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SMALL MOLECULE LIBRARIES; TANKYRASES;

EID: 84861813601     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057112436558     Document Type: Article

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