SCOPUS 정보 검색 플랫폼

Volumn 32, Issue 7, 2013, Pages 647-658

G protein-coupled estrogen receptor (GPER) agonist dual binding mode analyses toward understanding of its activation mechanism: A comparative homology modeling approach

(2) Arnatt, Christopher K a Zhang, Yan a

a VIRGINIA COMMONWEALTH UNIVERSITY (United States)

Author keywords

Agonism; Antagonism.; GPER; Homology modeling

Indexed keywords

ATOMS; BINDING ENERGY; CRYSTAL ATOMIC STRUCTURE; PROTEINS;

ACTIVATION MECHANISMS; AGONISMS; ANTAGONISM.; BINDING MODES; ESTROGEN RECEPTOR; G PROTEIN; G PROTEIN-COUPLED ESTROGEN RECEPTOR; HOMOLOGY MODELING; MODE ANALYSIS; MODELING APPROACH;

LIGANDS;

BETA 2 ADRENERGIC RECEPTOR; ESTRADIOL; G PROTEIN COUPLED ESTROGEN RECEPTOR AGONIST; G PROTEIN COUPLED ESTROGEN RECEPTOR ANTAGONIST; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; COMPARATIVE STUDY; CONFORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG BINDING; DRUG MECHANISM; HYDROGEN BOND; MOLECULAR MODEL; PRIORITY JOURNAL; RELIABILITY; SEQUENCE ALIGNMENT; SITE DIRECTED MUTAGENESIS; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 84880311135 PISSN: 18681743 EISSN: 18681751 Source Type: Journal
DOI: 10.1002/minf.201200136 Document Type: Article

Times cited : (28)

References (68)

1
- 79960176452
- M. Congreve, C. J. Langmead, J. S. Mason, F. H. Marshall, J. Med. Chem. 2011, 54, 4283-4311.
- (2011) J. Med. Chem. , vol.54 , pp. 4283-4311
- Congreve, M.¹ Langmead, C.J.² Mason, J.S.³ Marshall, F.H.⁴

2
- 84863247761
- M. Kontoyianni, Z. Liu, Curr. Med. Chem. 2012, 19, 544-556.
- (2012) Curr. Med. Chem. , vol.19 , pp. 544-556
- Kontoyianni, M.¹ Liu, Z.²

3
- 0034604451
- K. Palczewski, T. Kumasaka, T. Hori, C. A. Behnke, H. Motoshima, B. A. Fox, I. Le Trong, D. C. Teller, T. Okada, R. E. Stenkamp, et al., Science 2000, 289, 739-745.
- (2000) Science , vol.289 , pp. 739-745
- Palczewski, K.¹ Kumasaka, T.² Hori, T.³ Behnke, C.A.⁴ Motoshima, H.⁵ Fox, B.A.⁶ Le Trong, I.⁷ Teller, D.C.⁸ Okada, T.⁹ Stenkamp, R.E.¹⁰

4
- 33744761830
- A. Patny, P. V. Desai, M. A. Avery, Curr. Med. Chem. 2006, 13, 1667-1691.
- (2006) Curr. Med. Chem. , vol.13 , pp. 1667-1691
- Patny, A.¹ Desai, P.V.² Avery, M.A.³

5
- 0037235663
- C. Bizzantz, P. Bernard, M. Hibert, D. Rognan, Proteins: Struct. Funct. Bioinf. 2003, 50, 5-25.
- (2003) Proteins: Struct. Funct. Bioinf. , vol.50 , pp. 5-25
- Bizzantz, C.¹ Bernard, P.² Hibert, M.³ Rognan, D.⁴

6
- 36248970132
- S. G. F. Rasmussen, H.-J. Choi, D. M. Rosenbaum, T. S. Kobilka, F. S. Thian, P. C. Edwards, M. Burghammer, V. R. P. Ratnala, R. Sanishvili, R. F. Fischetti, et al., Nature 2007, 450, 383-387.
- (2007) Nature , vol.450 , pp. 383-387
- Rasmussen, S.G.F.¹ Choi, H.-J.² Rosenbaum, D.M.³ Kobilka, T.S.⁴ Thian, F.S.⁵ Edwards, P.C.⁶ Burghammer, M.⁷ Ratnala, V.R.P.⁸ Sanishvili, R.⁹ Fischetti, R.F.¹⁰

7
- 36448995359
- V. Cherezov, D. M. Rosenbaum, M. A. Hanson, S. G. Rasmussen, F. S. Thian, T. S. Kobilka, H. J. Choi, P. Kuhn, W. I. Weis, B. K. Kobilka, et al., Science 2007, 318, 1258-1265.
- (2007) Science , vol.318 , pp. 1258-1265
- Cherezov, V.¹ Rosenbaum, D.M.² Hanson, M.A.³ Rasmussen, S.G.⁴ Thian, F.S.⁵ Kobilka, T.S.⁶ Choi, H.J.⁷ Kuhn, P.⁸ Weis, W.I.⁹ Kobilka, B.K.¹⁰

8
- 47949129742
- T. Warne, M. J. Serrano-Vega, J. G. Baker, R. Moukhametzianov, P. C. Edwards, R. Henderson, A. G. Leslie, C. G. Tate, G. F. Schertler, Nature 2008, 454, 486-491.
- (2008) Nature , vol.454 , pp. 486-491
- Warne, T.¹ Serrano-Vega, M.J.² Baker, J.G.³ Moukhametzianov, R.⁴ Edwards, P.C.⁵ Henderson, R.⁶ Leslie, A.G.⁷ Tate, C.G.⁸ Schertler, G.F.⁹

9
- 4344581120
- T. Okada, M. Sugihara, A. N. Bondar, M. Elstner, P. Entel, V. Buss, J. Mol. Biol. 2004, 342, 571-583.
- (2004) J. Mol. Biol. , vol.342 , pp. 571-583
- Okada, T.¹ Sugihara, M.² Bondar, A.N.³ Elstner, M.⁴ Entel, P.⁵ Buss, V.⁶

10
- 56749103466
- V. P. Jaakola, M. T. Griffith, M. A. Hanson, V. Cherezov, E. Y. Chien, J. R. Lane, A. P. Ijzerman, R. C. Stevens, Science 2008, 322, 1211-1217.
- (2008) Science , vol.322 , pp. 1211-1217
- Jaakola, V.P.¹ Griffith, M.T.² Hanson, M.A.³ Cherezov, V.⁴ Chien, E.Y.⁵ Lane, J.R.⁶ Ijzerman, A.P.⁷ Stevens, R.C.⁸

11
- 85027927015
- B. Wu, E. Y. Chien, C. D. Mol, G. Fenalti, W. Liu, V. Katritch, R. Abagyan, A. Brooun, P. Wells, F. C. Bi, et al., Science 2010, 330, 1066-1071.
- (2010) Science , vol.330 , pp. 1066-1071
- Wu, B.¹ Chien, E.Y.² Mol, C.D.³ Fenalti, G.⁴ Liu, W.⁵ Katritch, V.⁶ Abagyan, R.⁷ Brooun, A.⁸ Wells, P.⁹ Bi, F.C.¹⁰

12
- 78449305788
- E. Y. Chien, W. Liu, Q. Zhao, V. Katritch, G. W. Han, M. A. Hanson, L. Shi, A. H. Newman, J. A. Javitch, V. Cherezov, et al., Science 2010, 330, 1091-1095.
- (2010) Science , vol.330 , pp. 1091-1095
- Chien, E.Y.¹ Liu, W.² Zhao, Q.³ Katritch, V.⁴ Han, G.W.⁵ Hanson, M.A.⁶ Shi, L.⁷ Newman, A.H.⁸ Javitch, J.A.⁹ Cherezov, V.¹⁰

13
- 79960070651
- T. Shimamura, M. Shiroishi, S. Weyand, H. Tsujimoto, G. Winter, V. Katritch, R. Abagyan, V. Cherezov, W. Liu, G. W. Han, et al., Nature 2011, 475, 65-70.
- (2011) Nature , vol.475 , pp. 65-70
- Shimamura, T.¹ Shiroishi, M.² Weyand, S.³ Tsujimoto, H.⁴ Winter, G.⁵ Katritch, V.⁶ Abagyan, R.⁷ Cherezov, V.⁸ Liu, W.⁹ Han, G.W.¹⁰

14
- 84862777405
- K. Haga, A. C. Kruse, H. Asada, T. Yurugi-Kobayashi, M. Shiroishi, C. Zhang, W. I. Weis, T. Okada, B. K. Kobilka, T. Haga, Nature 2012, 482, 547-551.
- (2012) Nature , vol.482 , pp. 547-551
- Haga, K.¹ Kruse, A.C.² Asada, H.³ Yurugi-Kobayashi, T.⁴ Shiroishi, M.⁵ Zhang, C.⁶ Weis, W.I.⁷ Okada, T.⁸ Kobilka, B.K.⁹ Haga, T.¹⁰

15
- 85165470900
- M. A. Hanson, C. B. Roth, E. Jo, M. T. Griffith, F. L. Scott, G. Reinhart, H. Desal, B. Clemons, S. M. Cahalan, S. C. Schuerer, et al., Science 2012, 335, 852-855.
- (2012) Science , vol.335 , pp. 852-855
- Hanson, M.A.¹ Roth, C.B.² Jo, E.³ Griffith, M.T.⁴ Scott, F.L.⁵ Reinhart, G.⁶ Desal, H.⁷ Clemons, B.⁸ Cahalan, S.M.⁹ Schuerer, S.C.¹⁰

16
- 84862777742
- H. Wu, D. Wacker, M. Mileni, V. Katritch, G. W. Han, E. Vardy, W. Liu, A. A. Thompson, X.-H. Huang, F. I. Carroll, et al., Nature 2012, 485, 327-332.
- (2012) Nature , vol.485 , pp. 327-332
- Wu, H.¹ Wacker, D.² Mileni, M.³ Katritch, V.⁴ Han, G.W.⁵ Vardy, E.⁶ Liu, W.⁷ Thompson, A.A.⁸ Huang, X.-H.⁹ Carroll, F.I.¹⁰

17
- 84861096654
- A. Manglik, A. C. Kruse, T. S. Kobilka, F. S. Thian, J. M. Mathiesen, R. K. Sunahara, L. Pardo, W. I. Weis, B. K. Kobilka, S. Granier, Nature 2012, 485, 321-326.
- (2012) Nature , vol.485 , pp. 321-326
- Manglik, A.¹ Kruse, A.C.² Kobilka, T.S.³ Thian, F.S.⁴ Mathiesen, J.M.⁵ Sunahara, R.K.⁶ Pardo, L.⁷ Weis, W.I.⁸ Kobilka, B.K.⁹ Granier, S.¹⁰

18
- 84861019261
- A. A. Thompson, W. Liu, E. Chun, V. Katritch, H. Wu, E. Vardy, X.-P. Huang, C. Trapella, R. Guerrini, G. Calo, et al., Nature 2012, 485, 395-399.
- (2012) Nature , vol.485 , pp. 395-399
- Thompson, A.A.¹ Liu, W.² Chun, E.³ Katritch, V.⁴ Wu, H.⁵ Vardy, E.⁶ Huang, X.-P.⁷ Trapella, C.⁸ Guerrini, R.⁹ Calo, G.¹⁰

19
- 84861075468
- S. Granier, A. Manglik, A. C. Kruse, T. S. Kobilka, F. S. Thian, W. I. Weis, B. K. Kobilka, Nature 2012, 485, 400-404.
- (2012) Nature , vol.485 , pp. 400-404
- Granier, S.¹ Manglik, A.² Kruse, A.C.³ Kobilka, T.S.⁴ Thian, F.S.⁵ Weis, W.I.⁶ Kobilka, B.K.⁷

20
- 84858236079
- P. S.-H. Park, Curr. Med. Chem. 2012, 19, 1146-1154.
- (2012) Curr. Med. Chem. , vol.19 , pp. 1146-1154
- Park, P.S.-H.¹

21
- 83755178196
- PRPR 535
- F. Fanelli, P. G. D. Benedetti, Chem. Rev. 2011, 111, PR 438 -PR 535.
- (2011) Chem. Rev. , vol.111 , pp. 438
- Fanelli, F.¹ Benedetti, P.G.D.²

22
- 80051658642
- S. G. F. Rasmussen, Y. Z. B. T. DeVree, A. C. Kruse, K. Y. Chung, T. S. Kobilka, F. S. Thian, P. S. Chae, E. Pardon, D. Calinski, J. M. Mathiesen, et al., Nature 2011, 477, 549-557.
- (2011) Nature , vol.477 , pp. 549-557
- Rasmussen, S.G.F.¹ Devree, Y.Z.B.T.² Kruse, A.C.³ Chung, K.Y.⁴ Kobilka, T.S.⁵ Thian, F.S.⁶ Chae, P.S.⁷ Pardon, E.⁸ Calinski, D.⁹ Mathiesen, J.M.¹⁰

23
- 84858236079
- P. S.-H. Park, Curr. Med. Chem. 2012, 19, 1146-1154.
- (2012) Curr. Med. Chem. , vol.19 , pp. 1146-1154
- Park, P.S.-H.¹

24
- 19744378683
- J. A. W. H. Ballestesteros, Methods Neurosci. 1995, 25, 366-428.
- (1995) Methods Neurosci. , vol.25 , pp. 366-428
- Ballestesteros, J.A.W.H.¹

25
- 43549095238
- E. R. Prossnitz, J. B. Arterburn, H. O. Smith, T. I. Oprea, L. A. Sklar, H. J. Hathaway, Physiology 2008, 70, 165-190.
- (2008) Physiology , vol.70 , pp. 165-190
- Prossnitz, E.R.¹ Arterburn, J.B.² Smith, H.O.³ Oprea, T.I.⁴ Sklar, L.A.⁵ Hathaway, H.J.⁶

26
- 0031282001
- C. Carmeci, D. A. Thompson, H. Z. Ring, U. Francke, R. J. Weigel, Genomics 1997, 45, 607-617.
- (1997) Genomics , vol.45 , pp. 607-617
- Carmeci, C.¹ Thompson, D.A.² Ring, H.Z.³ Francke, U.⁴ Weigel, R.J.⁵

27
- 14844343093
- C. M. Revankar, D. F. Cimino, L. A. Sklar, J. B. Arterburn, E. R. Prossnitz, Science 2005, 307, 1625-1630.
- (2005) Science , vol.307 , pp. 1625-1630
- Revankar, C.M.¹ Cimino, D.F.² Sklar, L.A.³ Arterburn, J.B.⁴ Prossnitz, E.R.⁵

28
- 69749110749
- E. R. Prossnitz, M. Barton, Prostaglandins Other Lipid Mediators 2009, 89, 89-97.
- (2009) Prostaglandins Other Lipid Mediators , vol.89 , pp. 89-97
- Prossnitz, E.R.¹ Barton, M.²

29
- 39749097760
- E. R. Prossnitz, L. A. Sklar, T. I. Oprea, J. B. Arterburn, Trends Pharmacol. Sci. 2008, 29, 116-123.
- (2008) Trends Pharmacol. Sci. , vol.29 , pp. 116-123
- Prossnitz, E.R.¹ Sklar, L.A.² Oprea, T.I.³ Arterburn, J.B.⁴

30
- 82155173499
- E. R. Prossnitz, M. Barton, Nat. Rev. Endocrinol. 2011, 7, 715-726.
- (2011) Nat. Rev. Endocrinol. , vol.7 , pp. 715-726
- Prossnitz, E.R.¹ Barton, M.²

31
- 33751272253
- E. J. Filardo, C. T. Graeber, J. A. Quinn, M. B. Resnick, D. Giri, R. A. DeLellis, M. M. Steinhoff, E. Sabo, Clin. Cancer Res. 2008, 12, 6359-6366.
- (2008) Clin. Cancer Res. , vol.12 , pp. 6359-6366
- Filardo, E.J.¹ Graeber, C.T.² Quinn, J.A.³ Resnick, M.B.⁴ Giri, D.⁵ Delellis, R.A.⁶ Steinhoff, M.M.⁷ Sabo, E.⁸

32
- 77955334004
- D. Wang, L. Hu, G. Zhang, L. Zhang, C. Chen, Endocrinology 2010, 38, 29-37.
- (2010) Endocrinology , vol.38 , pp. 29-37
- Wang, D.¹ Hu, L.² Zhang, G.³ Zhang, L.⁴ Chen, C.⁵

33
- 77955774697
- H. Arias-Pulido, M. Royce, Y. Gong, N. Joste, L. Lomo, S.-J. Lee, N. Chaher, C. Verschraegen, J. Lara, E. R. Prossnitz, et al., Breast Cancer Res. Treat. 2010, 123, 51-58.
- (2010) Breast Cancer Res. Treat. , vol.123 , pp. 51-58
- Arias-Pulido, H.¹ Royce, M.² Gong, Y.³ Joste, N.⁴ Lomo, L.⁵ Lee, S.-J.⁶ Chaher, N.⁷ Verschraegen, C.⁸ Lara, J.⁹ Prossnitz, E.R.¹⁰

34
- 80054739275
- H.-J. Luo, P. Luo, G.-L. Yang, Q.-L. Peng, M.-R. Liu, G. Tu, J. Breast Cancer 2011, 14, 185-190.
- (2011) J. Breast Cancer , vol.14 , pp. 185-190
- Luo, H.-J.¹ Luo, P.² Yang, G.-L.³ Peng, Q.-L.⁴ Liu, M.-R.⁵ Tu, G.⁶

35
- 85165481563
- E. J. Filardo, J. A. Quinn, K. I. Bland, A. R. J. Frackelton, Mol. Endocrinol. 2000, 14.
- (2000) Mol. Endocrinol. , vol.14
- Filardo, E.J.¹ Quinn, J.A.² Bland, K.I.³ Frackelton, A.R.J.⁴

36
- 3042547161
- M. Maggiolini, A. Vivacqua, G. Fasanella, A. G. Recchia, D. Sisci, V. Pessi, D. Montanaro, A. M. Musti, D. Picard, S. Ando, J. Biol. Chem. 2004, 279, 27008-27016.
- (2004) J. Biol. Chem. , vol.279 , pp. 27008-27016
- Maggiolini, M.¹ Vivacqua, A.² Fasanella, G.³ Recchia, A.G.⁴ Sisci, D.⁵ Pessi, V.⁶ Montanaro, D.⁷ Musti, A.M.⁸ Picard, D.⁹ Ando, S.¹⁰

37
- 33344461590
- A. Vivacqua, D. Bonofiglio, A. G. Recchia, A. M. Musti, D. Picard, S. Ando, M. Maggiolini, Mol. Endocrinol. 2006, 20, 631-646.
- (2006) Mol. Endocrinol. , vol.20 , pp. 631-646
- Vivacqua, A.¹ Bonofiglio, D.² Recchia, A.G.³ Musti, A.M.⁴ Picard, D.⁵ Ando, S.⁶ Maggiolini, M.⁷

38
- 70350449695
- A. Vivacqua, R. Lappano, P. De Marco, D. Sisci, S. Aquila, F. De Amicis, S. Ando, M. Maggiolini, Mol. Endocrinol. 2009, 23, 1815-1826.
- (2009) Mol. Endocrinol. , vol.23 , pp. 1815-1826
- Vivacqua, A.¹ Lappano, R.² De Marco, P.³ Sisci, D.⁴ Aquila, S.⁵ De Amicis, F.⁶ Ando, S.⁷ Maggiolini, M.⁸

39
- 33748923143
- A. Vivacqua, D. Bonofiglio, L. Albanito, A. Madeo, V. Rago, A. Carpino, A. M. Musti, D. Picard, S. Ando, M. Maggiolini, Mol. Endocrinol. 2006, 70, 1414-1423.
- (2006) Mol. Endocrinol. , vol.70 , pp. 1414-1423
- Vivacqua, A.¹ Bonofiglio, D.² Albanito, L.³ Madeo, A.⁴ Rago, V.⁵ Carpino, A.⁶ Musti, A.M.⁷ Picard, D.⁸ Ando, S.⁹ Maggiolini, M.¹⁰

40
- 33847755409
- L. Albanito, A. Madeo, R. Lappano, A. Vivacqua, V. Rago, A. Carpino, T. I. Oprea, E. R. Prossnitz, A. M. Musti, S. Ando, et al., Cancer Res. 2007, 67, 1859-1866.
- (2007) Cancer Res. , vol.67 , pp. 1859-1866
- Albanito, L.¹ Madeo, A.² Lappano, R.³ Vivacqua, A.⁴ Rago, V.⁵ Carpino, A.⁶ Oprea, T.I.⁷ Prossnitz, E.R.⁸ Musti, A.M.⁹ Ando, S.¹⁰

41
- 84863983261
- M. Barton, Steroids 2012, 77, 935-942.
- (2012) Steroids , vol.77 , pp. 935-942
- Barton, M.¹

42
- 12344307170
- P. Thomas, Y. Pang, E. J. Filardo, J. Dong, Endocrinology 2005, 146, 624-632.
- (2005) Endocrinology , vol.146 , pp. 624-632
- Thomas, P.¹ Pang, Y.² Filardo, E.J.³ Dong, J.⁴

43
- 33646366423
- C. G. Bologa, C. M. Revankar, S. M. Young, B. S. Edwards, J. B. Arterburn, A. S. Kiselyov, M. A. Parker, S. E. Tkachenko, N. P. Savchuck, L. A. Sklar, et al., Nat. Chem. Biol. 2006, 2, 207-212.
- (2006) Nat. Chem. Biol. , vol.2 , pp. 207-212
- Bologa, C.G.¹ Revankar, C.M.² Young, S.M.³ Edwards, B.S.⁴ Arterburn, J.B.⁵ Kiselyov, A.S.⁶ Parker, M.A.⁷ Tkachenko, S.E.⁸ Savchuck, N.P.⁹ Sklar, L.A.¹⁰

44
- 67349140294
- M. K. Dennis, R. Burai, C. Ramesh, W. K. Petrie, S. N. Alcon, T. K. Nayak, C. G. Bologa, A. Leitao, E. Brailoiu, E. Deliu, et al., Nat. Chem. Biol. 2009, 5, 421-427.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 421-427
- Dennis, M.K.¹ Burai, R.² Ramesh, C.³ Petrie, W.K.⁴ Alcon, S.N.⁵ Nayak, T.K.⁶ Bologa, C.G.⁷ Leitao, A.⁸ Brailoiu, E.⁹ Deliu, E.¹⁰

45
- 81255160989
- M. K. Dennis, A. S. Field, R. Burai, C. Ramesh, W. K. Petrie, C. G. Bologa, T. I. Oprea, Y. Yamaquchi, S.-I. Hayashi, L. A. Sklar, et al., J. Steroid Biochem. Mol. Biol. 2011, 127, 358-366.
- (2011) J. Steroid Biochem. Mol. Biol. , vol.127 , pp. 358-366
- Dennis, M.K.¹ Field, A.S.² Burai, R.³ Ramesh, C.⁴ Petrie, W.K.⁵ Bologa, C.G.⁶ Oprea, T.I.⁷ Yamaquchi, Y.⁸ Hayashi, S.-I.⁹ Sklar, L.A.¹⁰

46
- 77949568658
- R. Lappano, C. Rosano, P. De Marco, E. M. De Francecso, V. Pezzi, M. Maggiolini, Mol. Cell Endocrinol. 2010, 320, 162-170.
- (2010) Mol. Cell Endocrinol. , vol.320 , pp. 162-170
- Lappano, R.¹ Rosano, C.² De Marco, P.³ De Francecso, E.M.⁴ Pezzi, V.⁵ Maggiolini, M.⁶

47
- 46349096631
- Y. Pang, J. Dong, P. Thomas, Endocrinology 2008, 149, 3410-3426.
- (2008) Endocrinology , vol.149 , pp. 3410-3426
- Pang, Y.¹ Dong, J.² Thomas, P.³

48
- 84861737062
- R. Lappano, C. Rosano, M. F. Santolla, M. Pupo, E. M. De Francesco, P. De Marco, M. Ponassi, A. Spallarossa, A. Ranis, M. Maggiolini, Curr. Cancer Drug Targets 2012, 12, 531-542.
- (2012) Curr. Cancer Drug Targets , vol.12 , pp. 531-542
- Lappano, R.¹ Rosano, C.² Santolla, M.F.³ Pupo, M.⁴ De Francesco, E.M.⁵ De Marco, P.⁶ Ponassi, M.⁷ Spallarossa, A.⁸ Ranis, A.⁹ Maggiolini, M.¹⁰

49
- 84855767653
- RR 24
- R. Lappano, M. F. Santolla, M. Pupo, M. S. Sinicropi, A. Caruso, C. Rosano, M. Maggiolini, Breast Cancer Res. 2012, 14, R 12 -R 24.
- (2012) Breast Cancer Res. , vol.14 , pp. 12
- Lappano, R.¹ Santolla, M.F.² Pupo, M.³ Sinicropi, M.S.⁴ Caruso, A.⁵ Rosano, C.⁶ Maggiolini, M.⁷

50
- 36448991500
- M. A. Larkin, G. Blackshields, N. P. Brown, R. Chenna, P. A. McGettigan, H. McWilliam, F. Valentin, I. M. Wallace, A. Wilm, R. Lopez, et al., Bioinformatics 2007, 23, 2947-2948.
- (2007) Bioinformatics , vol.23 , pp. 2947-2948
- Larkin, M.A.¹ Blackshields, G.² Brown, N.P.³ Chenna, R.⁴ McGettigan, P.A.⁵ McWilliam, H.⁶ Valentin, F.⁷ Wallace, I.M.⁸ Wilm, A.⁹ Lopez, R.¹⁰

51
- 0027136282
- A. Sali, T. L. Blundell, J. Mol. Biol. 1993, 234, 779-815.
- (1993) J. Mol. Biol. , vol.234 , pp. 779-815
- Sali, A.¹ Blundell, T.L.²

52
- 0041919542
- M. L. Verdonk, J. C. Cole, M. J. Hartshorn, C. W. Murray, R. D. Taylor, Proteins 2003, 52, 609-623.
- (2003) Proteins , vol.52 , pp. 609-623
- Verdonk, M.L.¹ Cole, J.C.² Hartshorn, M.J.³ Murray, C.W.⁴ Taylor, R.D.⁵

53
- 77950896139
- I. Sela, G. Golan, M. Strajbl, D. Rivenzon-Segal, S. Bar-Haim, I. Bloch, B. Inbal, A. Shitrit, E. Ben-Zeev, M. Fichman, et al., Curr. Top. Med. Chem. 2010, 10, 638-656.
- (2010) Curr. Top. Med. Chem. , vol.10 , pp. 638-656
- Sela, I.¹ Golan, G.² Strajbl, M.³ Rivenzon-Segal, D.⁴ Bar-Haim, S.⁵ Bloch, I.⁶ Inbal, B.⁷ Shitrit, A.⁸ Ben-Zeev, E.⁹ Fichman, M.¹⁰

54
- 69049108756
- J. C. Mobarec, R. Sanchez, M. Filizola, J. Med. Chem. 2009, 52, 5207-5216.
- (2009) J. Med. Chem. , vol.52 , pp. 5207-5216
- Mobarec, J.C.¹ Sanchez, R.² Filizola, M.³

55
- 67349088738
- GPCR Dock 2008 participants
- C. L. Brooks III, J. S. Dixon, J. Moult, R. C. Stevens
- M. Michino, E. Abola, GPCR Dock 2008 participants, C. L. Brooks III, J. S. Dixon, J. Moult, R. C. Stevens, Nat. Rev. Drug Disc. 2009, 8, 455-463.
- (2009) Nat. Rev. Drug Disc. , vol.8 , pp. 455-463
- Michino, M.¹ Abola, E.²

56
- 80051521545
- GPCR Dock 2010 participants
- R. C. Stevens, R. Abagyan
- I. Kufareva, M. Rueda, V. Katritch, GPCR Dock 2010 participants, R. C. Stevens, R. Abagyan, Structure 2011, 19, 1108-1126.
- (2011) Structure , vol.19 , pp. 1108-1126
- Kufareva, I.¹ Rueda, M.² Katritch, V.³

57
- 44649172481
- M. A. Hanson, V. Cherezov, M. T. Griffith, C. B. Roth, V.-P. Jaakola, E. Y. T. Chien, J. Velasquez, P. Kuhn, R. C. Stevens, Structure 2008, 16, 897-905.
- (2008) Structure , vol.16 , pp. 897-905
- Hanson, M.A.¹ Cherezov, V.² Griffith, M.T.³ Roth, C.B.⁴ Jaakola, V.-P.⁵ Chien, E.Y.T.⁶ Velasquez, J.⁷ Kuhn, P.⁸ Stevens, R.C.⁹

58
- 73849149844
- M. P. Bokoch, Y. Zou, S. G. F. Ramussen, C. W. Liu, R. Nygaard, D. M. Rosenbaum, J. J. Fung, H.-J. Choi, F. S. Thian, T. S. Kobilka, et al., Nature 2010, 463, 108-112.
- (2010) Nature , vol.463 , pp. 108-112
- Bokoch, M.P.¹ Zou, Y.² Ramussen, S.G.F.³ Liu, C.W.⁴ Nygaard, R.⁵ Rosenbaum, D.M.⁶ Fung, J.J.⁷ Choi, H.-J.⁸ Thian, F.S.⁹ Kobilka, T.S.¹⁰

59
- 77955779227
- D. Wacker, G. Fenalti, M. A. Brown, V. Katritch, R. Abagyan, V. Cherezov, R. C. Stevens, J. Am. Chem. Soc. 2010, 132, 11443-11445.
- (2010) J. Am. Chem. Soc. , vol.132 , pp. 11443-11445
- Wacker, D.¹ Fenalti, G.² Brown, M.A.³ Katritch, V.⁴ Abagyan, R.⁵ Cherezov, V.⁶ Stevens, R.C.⁷

60
- 78651399683
- D. M. Rosenbaum, C. Zhang, J. A. Lyons, R. Holl, D. Aragao, D. H. Arlow, S. G. F. Rasmussen, H.-J. Choi, B. T. DeVee, R. K. Sunahara, et al., Nature 2011, 469, 236-240.
- (2011) Nature , vol.469 , pp. 236-240
- Rosenbaum, D.M.¹ Zhang, C.² Lyons, J.A.³ Holl, R.⁴ Aragao, D.⁵ Arlow, D.H.⁶ Rasmussen, S.G.F.⁷ Choi, H.-J.⁸ Devee, B.T.⁹ Sunahara, R.K.¹⁰

61
- 78651411166
- S. G. F. Rasmussen, H.-J. Choi, J. J. Fung, E. Pardon, P. Casarosa, P. S. Chae, B. T. DeVree, D. M. Rosenbaum, F. S. Thian, T. S. Kobilka, et al., Nature 2011, 469, 175-180.
- (2011) Nature , vol.469 , pp. 175-180
- Rasmussen, S.G.F.¹ Choi, H.-J.² Fung, J.J.³ Pardon, E.⁴ Casarosa, P.⁵ Chae, P.S.⁶ Devree, B.T.⁷ Rosenbaum, D.M.⁸ Thian, F.S.⁹ Kobilka, T.S.¹⁰

62
- 33846474121
- R. Dorsam, S. Gutkind, Nat. Rev. Cancer 2007, 7, 79-94.
- (2007) Nat. Rev. Cancer , vol.7 , pp. 79-94
- Dorsam, R.¹ Gutkind, S.²

63
- 84858228474
- M. Kolinski, A. Plazinska, K. Jozwiak, Curr. Med. Chem. 2012, 19, 1155-1163.
- (2012) Curr. Med. Chem. , vol.19 , pp. 1155-1163
- Kolinski, M.¹ Plazinska, A.² Jozwiak, K.³

64
- 33144459843
- T. W. Schwartz, T. M. Fimurer, B. Holst, M. M. Rosenkilde, C. E. Elling, Ann. Rev. Pharmacol. Toxicol. 2006, 46, 481-519.
- (2006) Ann. Rev. Pharmacol. Toxicol. , vol.46 , pp. 481-519
- Schwartz, T.W.¹ Fimurer, T.M.² Holst, B.³ Rosenkilde, M.M.⁴ Elling, C.E.⁵

65
- 84859311522
- X. Deupi, J. Standfuss, G. Schertler, Biochem. Soc. Trans. 2012, 40, 383-388.
- (2012) Biochem. Soc. Trans. , vol.40 , pp. 383-388
- Deupi, X.¹ Standfuss, J.² Schertler, G.³

66
- 79959564813
- G. Lebon, T. Warne, P. C. Edwards, K. Bennett, C. J. Langmead, A. G. W. Leslie, C. J. Tate, Nature 2011, 474, 521-525.
- (2011) Nature , vol.474 , pp. 521-525
- Lebon, G.¹ Warne, T.² Edwards, P.C.³ Bennett, K.⁴ Langmead, C.J.⁵ Leslie, A.G.W.⁶ Tate, C.J.⁷

67
- 84858225002
- S. Vanni, U. Rothlisberger, Curr. Med. Chem. 2012, 19, 1135-1145.
- (2012) Curr. Med. Chem. , vol.19 , pp. 1135-1145
- Vanni, S.¹ Rothlisberger, U.²

68
- 80054795187
- V. Katritch, R. Abagyan, Trends Pharmacol. Sci. 2011, 32, 637-643.
- (2011) Trends Pharmacol. Sci. , vol.32 , pp. 637-643
- Katritch, V.¹ Abagyan, R.²

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