Acute and repeated dose (28 days) oral safety studies of alibird in rats

Journal of Food Protection

Volumn 76, Issue 7, 2013, Pages 1226-1239

  Anadon, Arturo ^a   Martínez, María A ^a   Ares, Irma ^a   Castellano, Victor ^a   Martínez Larrañaga, Maria R ^a   Corzo, Nieves ^b   Olano, Agustin ^b   Montilla, Antonia ^b   Recio, Isidra ^b   Martínez Maqueda, Daniel ^b   Miralles, Beatriz ^b   Fornari, Tiziana ^b   García Risco, Monica R ^b   Gonzalez, Monserrat ^b   Reglero, Guillermo ^b,c  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c IMDEA FOOD INSTITUTE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84880265847     PISSN: 0362028X     EISSN: None     Source Type: Journal    
DOI: 10.4315/0362-028X.JFP-13-032     Document Type: Article

References (37)

1. Amin, A., and A. A. Hamza. 2005. Hepatoprotective effects of hibiscus, rosmarinus and salvia on azathioprine-induced toxicity in rats. Life Sci. 77:266-278.
2. Anadón, A., M. R. Martínez-Larrañaga, M. A. Martínez, I. Ares, M. R. García-Risco, F. J. Señorans, and G. Reglero. 2008. Acute oral safety study of rosemary extracts in rats. J. Food Prot. 71:790-795.
3. Aruoma, O. I., J. P. E. Spencer, R. Rossi, R. Aeschbach, A. Khan, N. Mahmood, A. Muñoz, A. Murcia, J. Butler, and B. Halliwell. 1996. An evaluation of the antioxidant and antiviral action of extracts of rosemary and Provençal herbs. Food Chem. Toxicol. 34:449-456.
4. Bakirel, T., U. Bakirel, O. U. Keles, S. G. Ulgen, and H. Yardibi. 2008. In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits. J. Ethnopharmacol. 116:64-73.
5. Bozin, B., N. Mimica-Dukic, I. Samojlik, and E. Jovin. 2007. Antimicrobial and antioxidant properties of rosmary and sage (Rosmarinus officinalis and Salvia officinalis, Lamiaceae) essential oils. J. Agric. Food Chem. 55:7879-7885.
6. Brobst, K. M., and C. E. Lott. 1966. Determination of some components in corn syrup by gas-liquid chromatography of trimethylsilyl derivatives. Cereal Chem. 43: 35-43.
7. Cardelle-Cobas, A., N. Corzo, C. Martínez-Villaluenga, A. Olano, and M. Villamiel. 2011. Effect of reaction conditions on the trisaccharide formation from lactulose and Lactozym 3000 L HP G. Eur. Food Res. Technol. 233:89-94.
8. Cardelle-Cobas, A., N. Corzo, A. Olano, C. Pélaez, T. Requena, and M. Ávila. 2011. Galactooligosaccharides derived from lactose and lactulose: influence of linkage and composition on Streptococcus, Lactobacillus and Bifidobacterium strains growth. Int. J. Food Microbiol. 149:81-87.
9. Cardelle-Cobas, A., C. Martínez-Villaluenga, M. Villamiel, A. Olano, and N. Corzo. 2008. Synthesis of oligosaccharides derived from lactulose and Pectinex Ultra SP-L. J. Agric. Food Chem. 56:3328-3333.
10. Cardelle-Cobas, A., A. Olano, N. Corzo, S. Kolida, M. Villamiel, and R. A. Rastall. 2012. In vitro fermentation of lactulose derived oligosaccharides by mixed faecal microbiota. J. Agric. Food Chem. 60:2024-2032.
11. Cardelle-Cobas, A., M. Villamiel, A. Olano, and N. Corzo. 2008. Isomerization of lactose-derived oligosaccharides. A case study using sodium aluminate. J. Agric. Food Chem. 56:10954-10959.
12. Carvalho, R. N., Jr., L. S. Moura, P. T. V. Rosa, and M. A. A. Meireles. 2005. Supercritical fluid extraction from rosemary (Rosmarinus officinalis): kinetic data, extract's global yield, composition, and antioxidant activity. J. Supercrit. Fluids 35:197-204.
13. Celiktas, O. Y., E. Bedir, and F. V. Sukan. 2007. In vitro antioxidant activities of Rosmarinus officinalis extracts treated with supercritical carbon dioxide. Food Chem. 101:1457-1464.
14. Chang, C., C. Chyau, C. Hsieh, Y. Wu, Y. B. Ker, H. Tsen, and R. Y. Peng. 2008. Relevance of phenolic diterpene constituents to antioxidant activity of supercritical CO2 extract from the leaves of rosemary. Nat. Prod. Res. 22:76-90.
15. Cheung, S., and J. Tai. 2007. Anti-proliferative and antioxidant properties of Rosmarinus officinalis. Oncol. Rep. 17:1525-1531.
16. Contreras, M. D. M., B. Gómez-Sala, P. Martín- Álvarez, L. Amigo, M. Ramos, and I. Recio. 2010. Monitoring the large-scale production of the antihypertensive peptides RYLGY and AYFYPEL by HPLCMS. Anal. Bioanal. Chem. 397:2825-2832.
17. Cuvelier, M. E., H. Richard, and C. Berset. 1996. Antioxidative activity and phenolic composition of pilot-plant and commercial extracts of sage and rosemary. J. Am. Oil Chem. Soc. 73:645-652.
18. Dunnett, C. W. 1995. A multiple comparison procedure for comparing several treatments with a control. J. Am. Stat. Assoc. 50: 1096-1121.
19. European Commission. 2008. Council Regulation (EC) No 440. Test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). Acute oral toxicity-fixed dose procedure. Off. J. Eur. Union L 142:145-150.
20. European Commission. 2008. Council Regulation (EC) No 440. Test methods pursuant to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). Repeated dose (28 days) toxicity oral. Off. J. Eur. Union L 142:210-215.
21. García-Risco, M. R., E. J. Hernández, G. Vicente, T. Fornari, F. J. Señoráns, and G. Reglero. 2011. Kinetic study of pilot-scale supercritical CO2 extraction of rosemary (Rosmarinus officinalis) leaves. J. Supercrit. Fluids 55:971-976.
22. Machado, D. G., L. E. Bettio, M. P. Cunha, J. C. Capra, J. B. Dalmarco, M. G. Pizzolatti, and A. L. Rodrigues. 2009. Antidepressant-like effect of the extract of Rosmarinus officinalis in mice: involvement of the monoaminergic system. Prog. Neuropsychopharmacol. Biol. Psychiatry 33:642-650.
23. Martínez-Villaluenga, C., A. Cardelle-Cobas, A. Olano, N. Corzo, M. Villamiel, and M. L. Jimeno. 2008. Enzymatic synthesis and identification of two trisaccharides produced from lactulose by transgalactosylation. J. Agric. Food Chem. 56:557-563.
24. Miguel, M., B. Hernández-Ledesma, R. López-Fandiño, and I. Recio. 2012. Bioactive peptides, p. 41-47. In L. Nollet and F. Toldrá (ed.), Handbook of analysis of active compounds in functional foods. Elsevier, Amsterdam.
25. Montilla, A., A. Olano, C. Martínez-Villaluenga, and N. Corzo. 2011. Study of influential factors on oligosaccharide formation by fructosyltransferase activity during stachyose hydrolysis by Pectinex Ultra SP-L. J. Agric. Food Chem. 59:10705-10711.
26. Mullally, M. M., H. Meisel, and R. J. Fitzgerald. 1997. Identification of a novel angiotensin-I-converting enzyme inhibitory peptide corresponding to a tryptic fragment of bovine b-lactoglobulin. FEBS Lett. 402:99-101.
27. Nagaoka, S., Y. Futamura, K. Miwa, T. Awano, K. Yamauchi, Y. Kanamaru, K. Tadashi, and T. Kuwata. 2001. Identification of novel hypocholesterolemic peptides derived from bovine milk b-lactoglobulin. Biochem. Biophys. Res. Commun. 281:11-17.
28. Pellegrini, A., C. Dettling, U. Thomas, and P. Hunziker. 2001. Isolation and characterization of four bactericidal domains in the bovine b-lactoglobulin. Biochim. Biophys. Acta Gen. Subj. 1526: 131-140.
29. Pérez-Fons, L., M. T. Garzón, and V. Micol. 2010. Relationship between the antioxidant capacity and effect of Rosemary (Rosmarinus officinalis L.) polyphenols on membrane phospholipid order. J. Agric. Food Chem. 58:161-171.
30. Petuely, F. 1957. The bifidus factor. Dtsch. Med. Wochenschr. 82: 1957-1960.
31. Pihlanto-Leppälä, A., T. Rokka, and H. Korhonen. 1998. Angiotensin I converting enzyme inhibitory peptides derived from bovine milk proteins. Int. Dairy J. 8:325-331.
32. Reverchon, E., and F. Sanatore. 1992. Isolation of rosemary oil: comparison between hydrodistillation and supercritical CO2 extraction. Flavour Fragr. J. 7:227-230.
33. Sanz, M. L., N. Polemis, V. Morales, N. Corzo, A. Drakoularakou, G. R. Gibson, and R. A. Rastall. 2005. In vitro investigation into the potential prebiotic activity of honey oligosaccharides. J. Agric. Food Chem. 53:2914-2921.
34. Sipola, M., P. Finckenberg, H. Vapaatalo, A. Pihlanto-Leppälä, H. Korhonen, R. Korpela, and M. Nurminen. 2002. a-Lactorphin and blactorphin improve arterial function in spontaneously hypertensive rats. Life Sci. 71:1245-1253.
35. Uchida, M., Y. Ohshiba, and O. Mogami. 2011. Novel dipeptidyl peptidase-4-inhibiting peptide derived from b-lactoglobulin. J. Pharmacol. Sci. 117:63-66.
36. Vicente, G., M. R. García-Risco, T. Fornari, and G. Reglero. 2012. Supercritical fractionation of rosemary extracts to improve antioxidant activity. Chem. Eng. Technol. 35:176-182.
37. Wakasa, Y., C. Tamakoshi, T. Ohno, S. Hirose, T. Goto, S. Nagaoka, and F. Takaiwa. 2011. The hypocholesterolemic activity of transgenic rice seed accumulating lactostatin, a bioactive peptide derived from bovine milk b-lactoglobulin. J. Agric. Food Chem. 59: 3845-3850. Educación y Ciencia