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Volumn 56, Issue 9, 2011, Pages 647-651

Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population

(30)  Hotta, Kikuko a   Kitamoto, Takuya a   Kitamoto, Aya a   Mizusawa, Seiho a   Matsuo, Tomoaki b   Nakata, Yoshio b   Kamohara, Seika c   Miyatake, Nobuyuki d   Kotani, Kazuaki e   Komatsu, Ryoya f   Itoh, Naoto g   Mineo, Ikuo h   Wada, Jun i   Yoneda, Masato j   Nakajima, Atsushi j   Funahashi, Tohru e   Miyazaki, Shigeru k   Tokunaga, Katsuto l   Masuzaki, Hiroaki m   Ueno, Takato n   more..


Author keywords

FTO; metabolic syndrome; MTMR9; SCG3

Indexed keywords

GENOMIC DNA;

EID: 80053261710     PISSN: 14345161     EISSN: 1435232X     Source Type: Journal    
DOI: 10.1038/jhg.2011.74     Document Type: Article
Times cited : (64)

References (31)
  • 1
    • 3242795814 scopus 로고    scopus 로고
    • Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome
    • DOI 10.2337/diabetes.53.8.2087
    • Carr, D. B., Utzschneider, K. M., Hull, R. L., Kodama, K., Retzlaff, B. M., Brunzell, J. D. et al. Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. Diabetes 53, 2087-2094 (2004). (Pubitemid 38970759)
    • (2004) Diabetes , vol.53 , Issue.8 , pp. 2087-2094
    • Carr, D.B.1    Utzschneider, K.M.2    Hull, R.L.3    Kodama, K.4    Retzlaff, B.M.5    Brunzell, J.D.6    Shofer, J.B.7    Fish, B.E.8    Knopp, R.H.9    Kahn, S.E.10
  • 2
    • 33747890012 scopus 로고    scopus 로고
    • Genetic determinants of the metabolic syndrome
    • DOI 10.1038/ncpcardio0638, PII NCPCARDIO0638
    • Pollex, R. L. & Hegele, R. A. Genetic determinants of the metabolic syndrome. Nat. Clin. Pract. Cardiovasc. Med. 3, 482-489 (2006). (Pubitemid 44288461)
    • (2006) Nature Clinical Practice Cardiovascular Medicine , vol.3 , Issue.9 , pp. 482-489
    • Pollex, R.L.1    Hegele, R.A.2
  • 3
    • 30544439060 scopus 로고    scopus 로고
    • Therapy insight: Adipocytokines in metabolic syndrome and related cardiovascular disease
    • DOI 10.1038/ncpcardio0380, PII N0380
    • Matsuzawa, Y. Therapy insight: adipocytokines in metabolic syndrome and related cardiovascular disease. Nat. Clin. Pract. Cardiovasc. Med. 3, 35-42 (2006). (Pubitemid 43078211)
    • (2006) Nature Clinical Practice Cardiovascular Medicine , vol.3 , Issue.1 , pp. 35-42
    • Matsuzawa, Y.1
  • 4
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • Hotta, K., Funahashi, T., Bodkin, N. L., Ortmeyer, H. K., Arita, Y., Hansen, B. C. et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 50, 1126-1133 (2001). (Pubitemid 32374544)
    • (2001) Diabetes , vol.50 , Issue.5 , pp. 1126-1133
    • Hotta, K.1    Funahashi, T.2    Bodkin, N.L.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6    Matsuzawa, Y.7
  • 5
    • 0027963471 scopus 로고
    • Clustering of hypertension, diabetes, and obesity in adult male twins: Same genes or same environments?
    • Carmelli, D., Cardon, L. R. & Fabsitz, R. Clustering of hypertension, diabetes, and obesity in adult male twins: same genes or same environments? Am. J. Hum. Genet. 55, 566-573 (1994). (Pubitemid 24272411)
    • (1994) American Journal of Human Genetics , vol.55 , Issue.3 , pp. 566-573
    • Carmelli, D.1    Cardon, L.R.2    Fabsitz, R.3
  • 6
    • 0030976711 scopus 로고    scopus 로고
    • Heritability of factors of the insulin resistance syndrome in women twins
    • DOI 10.1002/(SICI)1098-2272(1997)14: 3<241::AID-GEPI3>3.0.CO;2-8
    • Edwards, K. L., Newman, B., Mayer, E., Selby, J. V., Krauss, R. M. & Austin, M. A. Heritability of factors of the insulin resistance syndrome in women twins. Genet. Epidemiol. 14, 241-253 (1997). (Pubitemid 27240931)
    • (1997) Genetic Epidemiology , vol.14 , Issue.3 , pp. 241-253
    • Edwards, K.L.1    Newman, B.2    Mayer, E.3    Selby, J.V.4    Krauss, R.M.5    Austin, M.A.6
  • 8
    • 0032972817 scopus 로고    scopus 로고
    • The association of cardiovascular risk factor clustering related to insulin resistance syndrome (Syndrome X) between young parents and their offspring: The Bogalusa Heart Study
    • DOI 10.1016/S0021-9150(99)00025-8, PII S0021915099000258
    • Chen, W., Srinivasan, S. R., Elkasabany, A. & Berenson, G. S. The association of cardiovascular risk factor clustering related to insulin resistance syndrome (Syndrome X) between young parents and their offspring: the Bogalusa Heart Study. Atherosclerosis 145, 197-205 (1999). (Pubitemid 29292716)
    • (1999) Atherosclerosis , vol.145 , Issue.1 , pp. 197-205
    • Chen, W.1    Srinivasan, S.R.2    Elkasabany, A.3    Berenson, G.S.4
  • 9
    • 34248633997 scopus 로고    scopus 로고
    • Familial aggregation of components of the multiple metabolic syndrome in the framingham heart and offspring cohorts: Genetic analysis workshop problem 1
    • Lee, K. E., Klein, B. E. & Klein, R. Familial aggregation of components of the multiple metabolic syndrome in the Framingham Heart and Offspring Cohorts: genetic analysis workshop problem 1 BMC Genet. 4, S94-S98 (2003).
    • (2003) BMC Genet. , vol.4
    • Lee, K.E.1    Klein, B.E.2    Klein, R.3
  • 10
    • 0035993010 scopus 로고    scopus 로고
    • Clustering and heritability of insulin resistance in Chinese and Japanese hypertensive families: A stanford-asian pacific program in hypertension and insulin resistance sibling study
    • Wu, K. D., Hsiao, C. F., Ho, L. T., Sheu, W. H., Pei, D., Chuang, L. M. et al. Clustering and heritability of insulin resistance in Chinese and Japanese hypertensive families: a Stanford-Asian Pacific Program in Hypertension and Insulin Resistance Sibling Study. Hypertens. Res. 25, 529-536 (2002).
    • (2002) Hypertens. Res. , vol.25 , pp. 529-536
    • Wu, K.D.1    Hsiao, C.F.2    Ho, L.T.3    Sheu, W.H.4    Pei, D.5    Chuang, L.M.6
  • 11
    • 66249117320 scopus 로고    scopus 로고
    • Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome
    • Hotta, K., Nakamura, T., Takasaki, J., Takahashi, H., Takahashi, A., Nakata, Y. et al. Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome. J. Hum. Genet. 54, 230-235 (2009).
    • (2009) J. Hum. Genet. , vol.54 , pp. 230-235
    • Hotta, K.1    Nakamura, T.2    Takasaki, J.3    Takahashi, H.4    Takahashi, A.5    Nakata, Y.6
  • 16
    • 58149163142 scopus 로고    scopus 로고
    • Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
    • Willer, C. J., Speliotes, E. K., Loos, R. J., Li, S., Lindgren, C. M., Heid, I. M. et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat. Genet. 41, 25-34 (2009).
    • (2009) Nat. Genet. , vol.41 , pp. 25-34
    • Willer, C.J.1    Speliotes, E.K.2    Loos, R.J.3    Li, S.4    Lindgren, C.M.5    Heid, I.M.6
  • 17
    • 59149097625 scopus 로고    scopus 로고
    • Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations
    • Meyre, D., Delplanque, J., Chèvre, J. C., Lecoeur, C., Lobbens, S., Gallina, S. et al. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. Nat. Genet. 41, 157-159 (2009).
    • (2009) Nat. Genet. , Issue.41 , pp. 157-159
    • Meyre, D.1    Delplanque, J.2    Chèvre, J.C.3    Lecoeur, C.4    Lobbens, S.5    Gallina, S.6
  • 18
    • 67651236725 scopus 로고    scopus 로고
    • Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution
    • Lindgren, C. M., Heid, I. M., Randall, J. C., Lamina, C., Steinthorsdottir, V., Qi, L. et al. Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution. PLoS Genet. 5, e1000508 (2009).
    • (2009) PLoS Genet. , vol.5
    • Lindgren, C.M.1    Heid, I.M.2    Randall, J.C.3    Lamina, C.4    Steinthorsdottir, V.5    Qi, L.6
  • 19
    • 67651216024 scopus 로고    scopus 로고
    • NRXN3 is a novel locus for waist circumference: A genome-wide association study from the CHARGE consortium
    • Heard-Costa, N. L., Zillikens, M. C., Monda, K. L., Johansson, A., Harris, T. B., Fu, M. et al. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE consortium. PLoS Genet. 5, e1000539 (2009).
    • (2009) PLoS Genet. , vol.5
    • Heard-Costa, N.L.1    Zillikens, M.C.2    Monda, K.L.3    Johansson, A.4    Harris, T.B.5    Fu, M.6
  • 21
    • 73649136827 scopus 로고    scopus 로고
    • Association between obesity and polymorphisms in SEC16B TMEM18 GNPDA2 BDNF FAIM2 and MC4R in a Japanese population
    • Hotta, K., Nakamura, M., Nakamura, T., Matsuo, T., Nakata, Y., Kamohara, S. et al. Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. J. Hum. Genet. 54, 727-731 (2009).
    • (2009) J. Hum. Genet. , vol.54 , pp. 727-731
    • Hotta, K.1    Nakamura, M.2    Nakamura, T.3    Matsuo, T.4    Nakata, Y.5    Kamohara, S.6
  • 22
    • 78649508009 scopus 로고    scopus 로고
    • Polymorphisms in NRXN3 TFAP2B MSRA LYPLAL1 FTO and MC4R and their effect on visceral fat area in the Japanese population
    • Hotta, K., Nakamura, M., Nakamura, T., Matsuo, T., Nakata, Y., Kamohara, S. et al. Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population. J. Hum. Genet. 55, 738-742 (2010).
    • (2010) J. Hum. Genet. , vol.55 , pp. 738-742
    • Hotta, K.1    Nakamura, M.2    Nakamura, T.3    Matsuo, T.4    Nakata, Y.5    Kamohara, S.6
  • 24
    • 0034885541 scopus 로고    scopus 로고
    • A high-throughput SNP typing system for genome-wide association studies
    • DOI 10.1007/s100380170047
    • Ohnishi, Y., Tanaka, T., Ozaki, K., Yamada, R., Suzuki, H. & Nakamura, Y. A highthroughput SNP typing system for genome-wide association studies. J. Hum. Genet. 46, 471-477 (2001). (Pubitemid 32744120)
    • (2001) Journal of Human Genetics , vol.46 , Issue.8 , pp. 471-477
    • Ohnishi, Y.1    Tanaka, T.2    Ozaki, K.3    Yamada, R.4    Suzuki, H.5    Nakamura, Y.6
  • 25
    • 0032231375 scopus 로고    scopus 로고
    • Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus
    • DOI 10.1086/302114
    • Nielsen, D. M., Ehm, M. G. & Weir, B. S. Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus. Am. J. Hum. Genet. 63, 1531-1540 (1998). (Pubitemid 30418550)
    • (1998) American Journal of Human Genetics , vol.63 , Issue.5 , pp. 1531-1540
    • Nielsen, D.M.1    Ehm, M.G.2    Weir, B.S.3
  • 26
    • 67349166946 scopus 로고    scopus 로고
    • Detecting gene-gene interactions that underlie human diseases
    • Cordell, H. J. Detecting gene-gene interactions that underlie human diseases. Nat. Rev. Genet. 10, 392-404 (2009).
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 392-404
    • Cordell, H.J.1
  • 27
    • 77955398001 scopus 로고    scopus 로고
    • Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: The ARIC Study
    • Bi, M., Kao, W. H., Boerwinkle, E., Hoogeveen, R. C., Rasmussen-Torvik, L. J., Astor, B. C. et al. Association of rs780094 in GCKR with metabolic traits and incident diabetes and cardiovascular disease: the ARIC Study. PLoS One 5, e11690 (2010).
    • (2010) PLoS One , vol.5
    • Bi, M.1    Kao, W.H.2    Boerwinkle, E.3    Hoogeveen, R.C.4    Rasmussen-Torvik, L.J.5    Astor, B.C.6
  • 28
    • 75749086085 scopus 로고    scopus 로고
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    • Dupuis, J., Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., Jackson, A. U. et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat. Genet. 42, 105-116 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 105-116
    • Dupuis, J.1    Langenberg, C.2    Prokopenko, I.3    Saxena, R.4    Soranzo, N.5    Jackson, A.U.6
  • 29
    • 77957310400 scopus 로고    scopus 로고
    • The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes reduced fasting plasma glucose levels increased triglycerides levels and lower HOMAIR in Japanese population
    • Onuma, H., Tabara, Y., Kawamoto, R., Shimizu, I., Kawamura, R., Takata, Y. et al. The GCKR rs780094 polymorphism is associated with susceptibility of type 2 diabetes, reduced fasting plasma glucose levels, increased triglycerides levels and lower HOMAIR in Japanese population. J. Hum. Genet. 55, 600-604 (2010).
    • (2010) J. Hum. Genet. , vol.55 , pp. 600-604
    • Onuma, H.1    Tabara, Y.2    Kawamoto, R.3    Shimizu, I.4    Kawamura, R.5    Takata, Y.6
  • 31
    • 80052540977 scopus 로고    scopus 로고
    • Association of genetic variants for susceptibility to obesity with type 2 diabetes in Japanese individuals
    • Takeuchi, F., Yamamoto, K., Katsuya, T., Nabika, T., Sugiyama, T., Fujioka, A. et al. Association of genetic variants for susceptibility to obesity with type 2 diabetes in Japanese individuals. Diabetologia 54, 1350-1359 (2011).
    • (2011) Diabetologia , vol.54 , pp. 1350-1359
    • Takeuchi, F.1    Yamamoto, K.2    Katsuya, T.3    Nabika, T.4    Sugiyama, T.5    Fujioka, A.6


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