SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells

Nature Cell Biology

Volumn 11, Issue 2, 2009, Pages 143-153

  Bell, Robert D ^a   Deane, Rashid ^a   Chow, Nienwen ^b   Long, Xiaochun ^c   Sagare, Abhay ^a   Singh, Itender ^a   Streb, Jeffrey W ^c   Guo, Huang ^a,b   Rubio, Anna ^b   Van Nostrand, William ^d   Miano, Joseph M ^c   Zlokovic, Berislav V ^a  

^a Center for Neurodegenerative and Vascular Brain Disorders   (United States)

^b Socratech Research Laboratories   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; MYOCARDIN; SERUM RESPONSE FACTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN BLOOD VESSEL; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; GENE TRANSFER; HUMAN; HYPOXIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BLOOD-BRAIN BARRIER; CELLS, CULTURED; CEREBRAL ARTERIES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; HUMANS; LDL-RECEPTOR RELATED PROTEIN 1; MALE; MICE; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; NUCLEAR PROTEINS; SERUM RESPONSE FACTOR; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANS-ACTIVATORS; TRANSCRIPTIONAL ACTIVATION;

ANIMALIA;

EID: 59649110562     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/ncb1819     Document Type: Article

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