메뉴 건너뛰기




Volumn 13, Issue 3, 2005, Pages 244-250

Bioavailability and metabolic pharmacokinetics of rutin and quercetin in rats

Author keywords

Conjugated metabolites; Glucuronides; Pharmacokinetics; Quercetin; Rutin; Sulfates

Indexed keywords

BETA GLUCURONIDASE; DRUG METABOLITE; QUERCETIN; RUTOSIDE; SULFATASE;

EID: 28044467747     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (58)

References (29)
  • 1
    • 0034736046 scopus 로고    scopus 로고
    • Advances in flavonoid research since 1992
    • Harborne, J. B. and Williams, C. A. 2000. Advances in flavonoid research since 1992. Phytochemistry 55: 481-504.
    • (2000) Phytochemistry , vol.55 , pp. 481-504
    • Harborne, J.B.1    Williams, C.A.2
  • 2
    • 0033855919 scopus 로고    scopus 로고
    • The therapeutic potential of flavonoids
    • Wang, H. K. 2000. The therapeutic potential of flavonoids. Expert. Opin. Invest. Drug. 9: 2019-2103.
    • (2000) Expert. Opin. Invest. Drug. , vol.9 , pp. 2019-2103
    • Wang, H.K.1
  • 3
    • 0030068760 scopus 로고    scopus 로고
    • Flavonoid intake and coronary mortality in Finland: A cohort study
    • Knekt, P., Jarvinen, R., Reunanen, A. and Maatela, J. 1996. Flavonoid intake and coronary mortality in Finland: a cohort study. Br. Med. J. 312: 478-481.
    • (1996) Br. Med. J. , vol.312 , pp. 478-481
    • Knekt, P.1    Jarvinen, R.2    Reunanen, A.3    Maatela, J.4
  • 5
    • 0029867672 scopus 로고    scopus 로고
    • Flavonoids - Chemistry, metabolism, cardioprotective effects and dietary sources
    • Cook, N. C. and Samman, S. 1996. Flavonoids - chemistry, metabolism, cardioprotective effects and dietary sources. J. Nutr. Biochem. 7: 66-76.
    • (1996) J. Nutr. Biochem. , vol.7 , pp. 66-76
    • Cook, N.C.1    Samman, S.2
  • 6
    • 18244426782 scopus 로고    scopus 로고
    • The free radical scavenging activity of four flavonoids determined by the comet assay
    • Horvathova, K., Novotny, L. and Vachalkova, A. 2003. The free radical scavenging activity of four flavonoids determined by the comet assay. Neoplasma 50: 291-295.
    • (2003) Neoplasma , vol.50 , pp. 291-295
    • Horvathova, K.1    Novotny, L.2    Vachalkova, A.3
  • 7
    • 0033976054 scopus 로고    scopus 로고
    • Activity of monomeric, dimeric, and trimeric flavonoids on NO production, TNF-α secretion, and NF-κB-dependent gene expression in RAW 264.7 macrophages
    • Park, Y. C., Rimbach, G., Saliou, C., Valacchi, G. and Packer, L. 2000. Activity of monomeric, dimeric, and trimeric flavonoids on NO production, TNF-α secretion, and NF-κB-dependent gene expression in RAW 264.7 macrophages. FEBS. Lett. 464: 93-97.
    • (2000) FEBS. Lett. , vol.464 , pp. 93-97
    • Park, Y.C.1    Rimbach, G.2    Saliou, C.3    Valacchi, G.4    Packer, L.5
  • 8
    • 0142154309 scopus 로고    scopus 로고
    • Induction of rat hepatic and intestinal UDP-glucuronosyltransferases by naturally occurring dietary anticarcinogens
    • van der Logt, E. M., Roelofs, H. M., Nagengast, F. M. and Peters, W. H. 2003. Induction of rat hepatic and intestinal UDP-glucuronosyltransferases by naturally occurring dietary anticarcinogens. Carcinogenesis 24: 1651-1656.
    • (2003) Carcinogenesis , vol.24 , pp. 1651-1656
    • van der Logt, E.M.1    Roelofs, H.M.2    Nagengast, F.M.3    Peters, W.H.4
  • 9
    • 0034807826 scopus 로고    scopus 로고
    • Dietary agents in cancer prevention: Flavonoids and isoflavonoids
    • Birt, D. F., Hendrich, S. and Wang, W. 2001. Dietary agents in cancer prevention: flavonoids and isoflavonoids. Pharmacol. Ther. 90: 157-177.
    • (2001) Pharmacol. Ther. , vol.90 , pp. 157-177
    • Birt, D.F.1    Hendrich, S.2    Wang, W.3
  • 10
    • 0347510572 scopus 로고    scopus 로고
    • Lethal quercetin-digoxin interaction in pigs
    • Wang, Y. H., Chao, P. D. L., Hsiu, S. L., Wen, K. C. and Hou, Y. C. 2004. Lethal quercetin-digoxin interaction in pigs. Life Sci. 74: 1191-1197.
    • (2004) Life Sci. , vol.74 , pp. 1191-1197
    • Wang, Y.H.1    Chao, P.D.L.2    Hsiu, S.L.3    Wen, K.C.4    Hou, Y.C.5
  • 11
    • 0037032676 scopus 로고    scopus 로고
    • Quercetin significantly decreased cyclosporine oral bioavailability in pigs and rats
    • Hsiu, S. L., Hou, Y. C., Wang, Y. H., Tsao, C. W., Su, S. F. and Chao, P. D. L. 2002. Quercetin significantly decreased cyclosporine oral bioavailability in pigs and rats. Life Sci. 72: 227-235.
    • (2002) Life Sci. , vol.72 , pp. 227-235
    • Hsiu, S.L.1    Hou, Y.C.2    Wang, Y.H.3    Tsao, C.W.4    Su, S.F.5    Chao, P.D.L.6
  • 12
    • 28044469171 scopus 로고
    • Rutin: A new drug for the treatment of increased capillary fragility
    • Shanno, R. L. 1946. Rutin: a new drug for the treatment of increased capillary fragility. Am. J. Med. Sci. 211: 539-543.
    • (1946) Am. J. Med. Sci. , vol.211 , pp. 539-543
    • Shanno, R.L.1
  • 13
    • 0036123569 scopus 로고    scopus 로고
    • Effect of rutin and tannic acid supplements on cholesterol metabolism in rats
    • Park, S. Y., Bok, S. H., Jeon, S. M., Park, Y. B., Lee, S. J., Jeong, T. S. and Choi, M. S. 2002. Effect of rutin and tannic acid supplements on cholesterol metabolism in rats. Nutr. Res. 22: 283-295.
    • (2002) Nutr. Res. , vol.22 , pp. 283-295
    • Park, S.Y.1    Bok, S.H.2    Jeon, S.M.3    Park, Y.B.4    Lee, S.J.5    Jeong, T.S.6    Choi, M.S.7
  • 14
    • 3142583067 scopus 로고    scopus 로고
    • Mechanisms involved in the antiplatelet activity of rutin, a glycoside of the flavonol quercetin, in human platelets
    • Shen, J. R., Hsiao, G., Chou, P. H., Shen, M. Y. and Chou, D. S. 2004. Mechanisms involved in the antiplatelet activity of rutin, a glycoside of the flavonol quercetin, in human platelets. J. Agric. Food Chem. 52: 4414-4418.
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 4414-4418
    • Shen, J.R.1    Hsiao, G.2    Chou, P.H.3    Shen, M.Y.4    Chou, D.S.5
  • 15
    • 0030775534 scopus 로고    scopus 로고
    • Absorption, metabolism and health effects of dietary flavonoids in man
    • Hollman, P. C. H. and Katan, M. B. 1997. Absorption, metabolism and health effects of dietary flavonoids in man. Biomed. Pharmacother. 51: 305-310.
    • (1997) Biomed. Pharmacother. , vol.51 , pp. 305-310
    • Hollman, P.C.H.1    Katan, M.B.2
  • 16
    • 0029057329 scopus 로고
    • Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin
    • Manach, C., Morand, C. and Texier, O. 1995. Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin. J. Nutr. 125: 1911-1922.
    • (1995) J. Nutr. , vol.125 , pp. 1911-1922
    • Manach, C.1    Morand, C.2    Texier, O.3
  • 17
    • 0032977030 scopus 로고    scopus 로고
    • Solid-phase extraction and gas chromatography-mass spectrometry determination of kaempferol and quercetin in human urine after consumption of Ginkgo biloba tablets
    • Watson, D. G. and Oliveira, E. J. 1999. Solid-phase extraction and gas chromatography-mass spectrometry determination of kaempferol and quercetin in human urine after consumption of Ginkgo biloba tablets. J. Chromatogr. B. Biomed. Sci. Appl. 723: 203-210.
    • (1999) J. Chromatogr. B. Biomed. Sci. Appl. , vol.723 , pp. 203-210
    • Watson, D.G.1    Oliveira, E.J.2
  • 20
    • 0037627453 scopus 로고    scopus 로고
    • Disposition in of the flavonoid quercetin in rats after single intervenous and oral doses
    • Khaled, K. A., El-Sayed, Y. M. and Al-Hadiya, B. M. 2003. Disposition in of the flavonoid quercetin in rats after single intervenous and oral doses. Drug Dev. Ind. Pharm. 30: 397-403.
    • (2003) Drug Dev. Ind. Pharm. , vol.30 , pp. 397-403
    • Khaled, K.A.1    El-Sayed, Y.M.2    Al-Hadiya, B.M.3
  • 22
    • 0242664896 scopus 로고    scopus 로고
    • Enteric disposition and recycling of flavonoids and ginkgo flavonoids
    • Liu, Y., Liu, Y., Dai, Y., Xun, L. and Hu, M. 2003. Enteric disposition and recycling of flavonoids and ginkgo flavonoids. J. Altern. Complement Med. 9: 631-640.
    • (2003) J. Altern. Complement Med. , vol.9 , pp. 631-640
    • Liu, Y.1    Liu, Y.2    Dai, Y.3    Xun, L.4    Hu, M.5
  • 23
    • 0344642935 scopus 로고    scopus 로고
    • Comparison of Metabolic pharmacokinetics of baicalin and baicalein in rats
    • Lai, M. Y., Hsiu, S. L., Hou, Y. C., Tsai, S. Y. and Chao, P. D. L. 2003. Comparison of Metabolic pharmacokinetics of baicalin and baicalein in rats. J. Pharm. Pharmacol. 55: 199-209.
    • (2003) J. Pharm. Pharmacol. , vol.55 , pp. 199-209
    • Lai, M.Y.1    Hsiu, S.L.2    Hou, Y.C.3    Tsai, S.Y.4    Chao, P.D.L.5
  • 24
    • 0037083709 scopus 로고    scopus 로고
    • Comparison of metabolic pharmacokinetics of naringin and naringenin in rabbits
    • Hsiu, S. L., Huang, T. Y., Hou, Y. C. and Chao, P. D. L. 2002. Comparison of metabolic pharmacokinetics of naringin and naringenin in rabbits. Life Sci. 70: 1481-1489.
    • (2002) Life Sci. , vol.70 , pp. 1481-1489
    • Hsiu, S.L.1    Huang, T.Y.2    Hou, Y.C.3    Chao, P.D.L.4
  • 26
    • 0035692180 scopus 로고    scopus 로고
    • Human metabolism of dietary flavonoids: Identification of plasma metabolites of quercetin
    • Day, A. J., Mellon, F., Barron, D., Sarrazin, G., Morgan, M. R. and Williamson, G. 2001. Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin. Free Radic. Res. 35: 941-952.
    • (2001) Free Radic. Res. , vol.35 , pp. 941-952
    • Day, A.J.1    Mellon, F.2    Barron, D.3    Sarrazin, G.4    Morgan, M.R.5    Williamson, G.6
  • 28
    • 0036561383 scopus 로고    scopus 로고
    • Effect of quereetin and its conjugated metabolite on the hydrogen peroxide-induced intracellular production of reactive oxygen species in mouse fibroblasts
    • Shirai, M., Yamanishi, R., Moon, J. H., Murota, K. and Terao, J. 2002. Effect of quereetin and its conjugated metabolite on the hydrogen peroxide-induced intracellular production of reactive oxygen species in mouse fibroblasts. Biosci. Biotechnol. Biochem. 66: 1015-1021.
    • (2002) Biosci. Biotechnol. Biochem. , vol.66 , pp. 1015-1021
    • Shirai, M.1    Yamanishi, R.2    Moon, J.H.3    Murota, K.4    Terao, J.5
  • 29
    • 0344255791 scopus 로고    scopus 로고
    • Morin sulfates/glucuronindes exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock
    • Fang, S. H., Hou, Y. C., Chang, W. C., Hsiu, S. L., Chao, P. D. L. and Chiang, B. L. 2003. Morin sulfates/glucuronindes exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock. Life Sci. 74: 743-756.
    • (2003) Life Sci. , vol.74 , pp. 743-756
    • Fang, S.H.1    Hou, Y.C.2    Chang, W.C.3    Hsiu, S.L.4    Chao, P.D.L.5    Chiang, B.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.