Formulation design and evalution of rutin loaded selfemulsifying drug delivary system (SEDDs) using edible oil

Asian Journal of Pharmaceutical and Clinical Research

Volumn 5, Issue 1, 2012, Pages 76-78

  Kumar, Pal Vishesh ^a   Bhopal, Azaz Khan Pbri ^a  

^a Sirmadanlal institute of pharmacy Etawah   (India)

Author keywords

Self emulsifying drug delivery system rutin loaded drug in vitro hepatotoxicity

Indexed keywords

DEOXYCHOLATE SODIUM; EDIBLE OIL; MACROGOL 4000; MACROGOL 6000; POLYVINYL PYRROLIDONE K17; POLYVINYL PYRROLIDONE K30; POVIDONE; RUTOSIDE; UNCLASSIFIED DRUG;

ARTICLE; DIFFUSION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; IN VITRO STUDY; MELTING POINT; PARTICLE SIZE; PRECIPITATION; SELFEMULSIFYING DRUG DELIVERY SYSTEM; SOLUBILIZATION; TURBIDITY; VISCOSITY;

EID: 84856792609     PISSN: 09742441     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Linjie Liu, Xiujuan Pang, Wei Zhang, Siling Wang School of Pharmacy Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang 110016, China Received 5 April 2007; Revised 6 June 2007; Accepted 26 June 2007cn.VOL105,Marcl Dekker, Inc.,NEW York,
2. Greenberger NJ, Rodgers JB and Isselbache K Jr.(1966) Absorption of medium and long chain triglyceride: factor influencing their hydrolysis and transport. J Clin Invest 45:217-227
3. PA Patel, GM Chaulang, A Akolkotkar, SS Mutha, SR Hardikar and AV Bhosale, Self Emulsifying Drug Delivery System: A Review Department of Pharmaceutics, SGRS College of Pharmacy, Saswad, Pune (MS), India. PIN-412301Research J. Pharm. and Tech. 1(4): Oct.-Dec. 2008,
4. Claudine Manach, Christine Morand, et.al (2009) Christian Demigné, Odile Texier, Françoise Régérat, Christian Rémésy Bioavailability of rutin and quercetin. In rats FEBS Letters, Volume 409, Issue 1,
5. Attenwood D and Florence AT.(1983),Surfactant system: their chemistry, pharmacy and biology.Champman and Hall. London.74:1140-1141
6. Dunkan QM, Craig M, Patel J and Ashford M (2000).pharmaceutical emulsion and suspension. VOL-105,Marcel Dekker, Inc.,New yar
7. S. Shafiq, et al. Development and bioavailability assessment of ramipril nanoemulsion formulation Eur. J.Pharm. Biopharm 2007; 66: 227-243
8. Patil P, Vandana P, paradkar P. Formulation of self emulsifying drug delivery system for simvastatin: In vitro and in vivo evaluation. Acta pharma. 2007; 57: 111-122
9. Craig DQM, Barker SA, Banning D, Booth SW. An investigation into the mechanism of self-emulsification using particle size analysis and low frequency dielectric spectroscopy. Into J Pharm. 1995; 114:103-10
10. Vishesh Kumar Pal, Sir Madanlal Institute of Pharmacy Etawah, U.P. Journal of Pharmaceutical Research and Opinion 1:3 (2011) 80-84. SEDDS
11. Nazzal S, Smalyukh II, Lavrentovich OD, Mansoor AK. Preparation and in vitro characterization of a eutectic basedsemisolid self-nanoemulsified drug delivery system (SNEDDS) of ubiquinone: mechanism and progress of emulsion formulation. Int J Pharm. 2002; 235: 247-265.
12. Gong K, Darr JA, Rehman IU. Supercritical fluid assisted impregnation of indomethacin into chitosan thermosets for controlled release applications. Int J Pharm. 2006; 315(1-2):93-8
13. B. D. Tarr, S. H. Yallkowsky. Enhanced intestinal absorption of cyclosporine in rats through the reduction of emulsion droplet size. Pharm. Res, 1989, 6: 40-43.
14. Gershanik, S. Positively-charged self-emulsifying oil formulation for improving oral bioavalability of progesterone. Pharm. Dev. Technol., 1996, 1: 147-157.
15. Wu, Y. Wang, L. Enhanced bioavailability of silymarin by self-Micro emulsifying drug delivery system. Eur. J. Pharm. Biopharm., 2006, 63: 288-294.
16. Vasanthavada, M. and Serajuddin, A.T.M. (2007) Lipid-based self-emulsifying soliddispersions. In Oral Lipid-Based Formulations: Enhancing Bioavailability of Poorly Water-Soluble Drugs (Hauss, D.J., ed.), pp. 149-184, Informa Healthcare
17. Serajuddin, A.T.M. et al. (1988) Effect of vehicle amphiphilicity on the dissolution and bioavailability of a poorly water-soluble drug from solid dispersions. J. Pharm.Sci. 77, 414-417
18. Khoo, S.M. et al. (2000) The formulation of halofantrine as either non-solubilisingPEG 6000 or solubilising lipid based solid dispersions: physical stability and absolute bioavailability assessment. Int. J. Pharm. 205, 65-78
19. Patil, P. and Paradkar, A. (2006) Porous polystyrene beads as carriers for selfemulsifyingsystem containing loratadine. AAPSPharm.Sci.Tech.10.1208/pt070128
20. You, J. et al. (2006) Study of the preparation of sustained-release microspheres containing zedoary turmeric oil by the emulsion-solvent-diffusion method and evaluation of the self-emulsification and bioavailability of the oil. Colloid. Surf. B. 48, 35-41
21. Attama, A.A. and Nkemnele, M.O. (2005) In vitro evaluation of drug release from self micro-emulsifying drug delivery systems using a biodegradable homolipid from Capra hircus. Int. J. Pharm. 304, 4-10
22. Hu, Y.X. et al. (2005) Preparation and evaluation of 5-FU/PLGA/gene nanoparticles. Key Eng. Mat. 288-289 147-150
23. Trickler, W.J. et al. (2008) A novel nanoparticle formulation for sustained paclitaxel delivery. AAPS Pharm. Sci. Tech. 10.1208/s12249-008-9063-7
24. Kim, J.Y. and Ku, Y.S. (2000) Enhanced absorption of indomethacin after oral orrectal administration of a self-emulsifying system containing indomethacin to rats. Int. J. Pharm. 194, 81-89