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Volumn 39, Issue 1, 2010, Pages 15-35

Antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of Ruta graveolens infusion and rutin in nicotinamide-streptozotocin-induced diabetic rats

Author keywords

Nicotinamide streptozotocin induced diabetic rats; Ruta graveolens infusion; Rutin

Indexed keywords

C PEPTIDE; GLUCOSE 6 PHOSPHATASE; GLYCOGEN PHOSPHORYLASE; HEXOKINASE; INSULIN; NICOTINAMIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; RESISTIN; RUTA GRAVEOLENS EXTRACT; RUTOSIDE; STREPTOZOCIN;

EID: 77951229157     PISSN: 03510042     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (125)

References (99)
  • 1
    • 0003725206 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications
    • World Health Organization, WHO/NCD/ NCS/99.2, Geneva
    • World Health Organization. Definition, diagnosis and classification of diabetes mellitus and its complications. In: Report of a WHO Consultation, Part 1: Diagnosis and classification of diabetes mellitus. WHO/NCD/ NCS/99.2, Geneva, 1999.
    • (1999) Report of A WHO Consultation, Part 1: Diagnosis and Classification of Diabetes Mellitus
  • 2
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-1053.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 3
    • 28844503938 scopus 로고    scopus 로고
    • Prevalence, predisposition and prevention of type II diabetes
    • Cheng D. Prevalence, predisposition and prevention of type II diabetes. Nutr Metab 2005;2:2-29.
    • (2005) Nutr Metab , vol.2 , pp. 2-29
    • Cheng, D.1
  • 4
    • 34249279490 scopus 로고    scopus 로고
    • Animal models in type 2 diabetes research: An overview
    • Srinivasan K, Ramarao P. Animal models in type 2 diabetes research: an overview. Indian J Med Res 2007;125:451-472.
    • (2007) Indian J Med Res , vol.125 , pp. 451-472
    • Srinivasan, K.1    Ramarao, P.2
  • 5
    • 33846929465 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator activated receptors on lipoprotein metabolism and glucose control in type 2 diabetes mellitus
    • Rosenson RS. Effects of peroxisome proliferator activated receptors on lipoprotein metabolism and glucose control in type 2 diabetes mellitus. Am J Cardiol 2007; 99 (Suppl): 96B-104B.
    • (2007) Am J Cardiol , vol.99 , Issue.SUPPL.
    • Rosenson, R.S.1
  • 6
    • 33747154772 scopus 로고    scopus 로고
    • Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network
    • Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 2006;126(4):789-799.
    • (2006) Cell , vol.126 , Issue.4 , pp. 789-799
    • Bookout, A.L.1    Jeong, Y.2    Downes, M.3    Yu, R.T.4    Evans, R.M.5    Mangelsdorf, D.J.6
  • 9
    • 0035851187 scopus 로고    scopus 로고
    • PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
    • Rosen ED, Spiegelman BM. PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J Biol Chem 2001;276(41):37731-37734.
    • (2001) J Biol Chem , vol.276 , Issue.41 , pp. 37731-37734
    • Rosen, E.D.1    Spiegelman, B.M.2
  • 11
    • 0034254655 scopus 로고    scopus 로고
    • FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family
    • Holcomb IN, Kabakoff RC, Chan B, Baker TW, Gurney A, Henzel W. FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family. EMBO J 2000;19:4046-4055.
    • (2000) EMBO J , vol.19 , pp. 4046-4055
    • Holcomb, I.N.1    Kabakoff, R.C.2    Chan, B.3    Baker, T.W.4    Gurney, A.5    Henzel, W.6
  • 12
    • 0035815608 scopus 로고    scopus 로고
    • A cysteinerich adipose tissue-specific secretory factor inhibits adipocyte differentiation
    • Kim KH, Lee K, Moon YS, Sul HS. A cysteinerich adipose tissue-specific secretory factor inhibits adipocyte differentiation. J Biol Chem 2001;276:11252-11256.
    • (2001) J Biol Chem , vol.276 , pp. 11252-11256
    • Kim, K.H.1    Lee, K.2    Moon, Y.S.3    Sul, H.S.4
  • 13
    • 0037241112 scopus 로고    scopus 로고
    • Adipose-derived resistin and gut-derived resistinlike molecule-beta selectively impair insulin action on glucose production
    • Rajala MW, Obici S, Scherer PE, Rossetti L. Adipose-derived resistin and gut-derived resistinlike molecule-beta selectively impair insulin action on glucose production. J Clin Invest 2003;111:225-230.
    • (2003) J Clin Invest , vol.111 , pp. 225-230
    • Rajala, M.W.1    Obici, S.2    Scherer, P.E.3    Rossetti, L.4
  • 14
    • 77951226118 scopus 로고    scopus 로고
    • Traditional herbal medicines used for the treatment of diabetes among two major tribal groups in South Tamil Nadu, India
    • Ayyanar M, Sankarasivaraman K, Ignacimuthu S. Traditional herbal medicines used for the treatment of diabetes among two major tribal groups in South Tamil Nadu, India. Ethnobotanical Leaflets 2008;12:276-280.
    • (2008) Ethnobotanical Leaflets , vol.12 , pp. 276-280
    • Ayyanar, M.1    Sankarasivaraman, K.2    Ignacimuthu, S.3
  • 15
    • 65649126968 scopus 로고    scopus 로고
    • A database for medicinal plants used in the treatment of diabetes and its secondary complications
    • Arulrayan N, Rangasamy S, James E, Pitchai D. A database for medicinal plants used in the treatment of diabetes and its secondary complications. Bioinformation 2007;2(1):22-23.
    • (2007) Bioinformation , vol.2 , Issue.1 , pp. 22-23
    • Arulrayan, N.1    Rangasamy, S.2    James, E.3    Pitchai, D.4
  • 16
    • 32544453234 scopus 로고    scopus 로고
    • Anti-inflammatory effect of R. graveolens L. in murine macrophage cells
    • Raghav SK, Gupta B, Agrawal C, Goswami K, Das HR. Anti-inflammatory effect of R. graveolens L. in murine macrophage cells. J Ethnopharmacol 2006;104:234-239.
    • (2006) J Ethnopharmacol , vol.104 , pp. 234-239
    • Raghav, S.K.1    Gupta, B.2    Agrawal, C.3    Goswami, K.4    Das, H.R.5
  • 17
    • 3042606421 scopus 로고    scopus 로고
    • Ruta selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer
    • Pathak S, Multani AS, Banerji P, Banerji P. Ruta selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: a novel treatment for human brain cancer. Int J Oncol 2003;23:975-982.
    • (2003) Int J Oncol , vol.23 , pp. 975-982
    • Pathak, S.1    Multani, A.S.2    Banerji, P.3    Banerji, P.4
  • 18
    • 32544453208 scopus 로고
    • CSIR. In: Chadha YR, editor, Publications and Information Directorate, Council of Scienti?c and Industrial Research, India
    • CSIR. In: Chadha YR, editor. The Wealth of India - A dictionary of Indian raw materials and industrial products, Vol. IX. Publications and Information Directorate, Council of Scienti?c and Industrial Research, India, 1988; pp. 95-96.
    • (1988) The Wealth of India - A Dictionary of Indian Raw Materials and Industrial Products , vol.9 , pp. 95-96
  • 19
    • 33751391867 scopus 로고
    • Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in The Netherlands
    • Hertog MG, Hollman PC, Katan MB. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in The Netherlands. J Agric Food Chemist 1992;40:2379-2383.
    • (1992) J Agric Food Chemist , vol.40 , pp. 2379-2383
    • Hertog, M.G.1    Hollman, P.C.2    Katan, M.B.3
  • 20
    • 0027504187 scopus 로고
    • Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen elderly study
    • Hertog MG, Feskens EJ, Hollmann PC, Katan MB, Kronthout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen elderly study. Lancet 1993;342:1007-1011.
    • (1993) Lancet , vol.342 , pp. 1007-1011
    • Hertog, M.G.1    Feskens, E.J.2    Hollmann, P.C.3    Katan, M.B.4    Kronthout, D.5
  • 21
    • 0027291905 scopus 로고
    • Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands
    • Hertog MG, Hollman PC, Katan MB, Kromhout D. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in The Netherlands. Nutr Cancer 1993;20:21-29.
    • (1993) Nutr Cancer , vol.20 , pp. 21-29
    • Hertog, M.G.1    Hollman, P.C.2    Katan, M.B.3    Kromhout, D.4
  • 22
    • 0342264489 scopus 로고    scopus 로고
    • Flavonoid content of several vegetables and their antioxidant activity
    • Chu YH, Chang CL, Hsu HF. Flavonoid content of several vegetables and their antioxidant activity. J Sci Food Agric 2000;80:561-566.
    • (2000) J Sci Food Agric , vol.80 , pp. 561-566
    • Chu, Y.H.1    Chang, C.L.2    Hsu, H.F.3
  • 23
    • 33645103657 scopus 로고    scopus 로고
    • Antihyperglycemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic Wistar rats
    • Kamalakkannan N, Prince SM. Antihyperglycemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic Wistar rats. Basic Clin Pharmacol Toxicol 2006;98(1):97-103.
    • (2006) Basic Clin Pharmacol Toxicol , vol.98 , Issue.1 , pp. 97-103
    • Kamalakkannan, N.1    Prince, S.M.2
  • 24
    • 0043063961 scopus 로고    scopus 로고
    • Antioxidative flavonoid quercetin: Implication of its intestinal absorption and metabolism
    • Murota K, Terao J. Antioxidative flavonoid quercetin: implication of its intestinal absorption and metabolism. Arch Biochem Biophys 2003;417:12-17.
    • (2003) Arch Biochem Biophys , vol.417 , pp. 12-17
    • Murota, K.1    Terao, J.2
  • 25
    • 0020626421 scopus 로고
    • Flavonoids, a class of natural products of high pharmacological potency
    • Havsteen B. Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol 1983;32:1141-1148.
    • (1983) Biochem Pharmacol , vol.32 , pp. 1141-1148
    • Havsteen, B.1
  • 26
    • 0036915813 scopus 로고    scopus 로고
    • Protective effect of rutin on paracetamol-and CCl4-induced hepatotoxicity in rodents
    • Janbaz KH, Saeed SA, Gilani AH. Protective effect of rutin on paracetamol-and CCl4-induced hepatotoxicity in rodents. Fitoterapia 2002;73:557-563.
    • (2002) Fitoterapia , vol.73 , pp. 557-563
    • Janbaz, K.H.1    Saeed, S.A.2    Gilani, A.H.3
  • 27
    • 77951245882 scopus 로고
    • Canadian Council on Animal Care, CCAC, Ottawa, Ontario, Canada
    • Canadian Council on Animal Care. Guide to the care and use of experimental animals. Vol. 2, CCAC, Ottawa, Ontario, Canada, 1993.
    • (1993) Guide to The Care and Use of Experimental Animals , vol.2
  • 28
    • 33645534919 scopus 로고
    • Evaluation of antihyperglycemic properties of traditional plant treatment for diabetes in streptozotocin diabetic and db/db mice
    • In: Shafrir E, editor, London: Smith-Gordon
    • Swanston-Flatt SK, Day C, Flatt PR, Bailey CJ. Evaluation of antihyperglycemic properties of traditional plant treatment for diabetes in streptozotocin diabetic and db/db mice. In: Shafrir E, editor. Frontiers in diabetes research. Lessons from animal diabetes. Vol. 3. London: Smith-Gordon, 1995; pp. 286-293.
    • (1995) Frontiers In Diabetes Research. Lessons From Animal Diabetes , vol.3 , pp. 286-293
    • Swanston-Flatt, S.K.1    Day, C.2    Flatt, P.R.3    Bailey, C.J.4
  • 29
    • 77951218334 scopus 로고
    • 4th edition. London: Henry Kumpton
    • Claus FD. Phamacognosy, 4th edition. London: Henry Kumpton, 1961.
    • (1961) Phamacognosy
    • Claus, F.D.1
  • 30
    • 33748675277 scopus 로고    scopus 로고
    • Antidiabetic activity of benzyl tetra isoquinoline alkaloid berberine in streptozotocin-nicotinamide induced type 2 diabetic rats
    • Punitha IS, Shirwaikar A, Shirwaikar A. Antidiabetic activity of benzyl tetra isoquinoline alkaloid berberine in streptozotocin-nicotinamide induced type 2 diabetic rats. Diabetol Croat 2005;34(4):117-128.
    • (2005) Diabetol Croat , vol.34 , Issue.4 , pp. 117-128
    • Punitha, I.S.1    Shirwaikar, A.2    Shirwaikar, A.3
  • 32
    • 0003072603 scopus 로고
    • Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor
    • Trinder P. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann Clin Biochem 1969;6:24-27.
    • (1969) Ann Clin Biochem , vol.6 , pp. 24-27
    • Trinder, P.1
  • 33
    • 0021996684 scopus 로고
    • Serum fructosamine concentration as a measure of blood glucose control in type 1 (insulin dependent) diabetes
    • Baker JR, Metcalf PA, Holdway I, Johnson RN. Serum fructosamine concentration as a measure of blood glucose control in type 1 (insulin dependent) diabetes. Br Med J 1985;290:352-355.
    • (1985) Br Med J , vol.290 , pp. 352-355
    • Baker, J.R.1    Metcalf, P.A.2    Holdway, I.3    Johnson, R.N.4
  • 35
    • 0021318358 scopus 로고
    • C-peptide measurement: Methods and clinical utility
    • Bonser A, Garcia-Webb P. C-peptide measurement: methods and clinical utility. CRC Crit Rev Clin Lab Sci 1984;19:279-352.
    • (1984) CRC Crit Rev Clin Lab Sci , vol.19 , pp. 279-352
    • Bonser, A.1    Garcia-Webb, P.2
  • 37
    • 0037733561 scopus 로고
    • The hexokinase and phosphoglucoisomerase activities of aortic and pulmonary artery tissues in individuals of various ages
    • Branstrup N, Kirk JE, Bruni C. The hexokinase and phosphoglucoisomerase activities of aortic and pulmonary artery tissues in individuals of various ages. J Gerontol 1963;238:3280.
    • (1963) J Gerontol , vol.238 , pp. 3280
    • Branstrup, N.1    Kirk, J.E.2    Bruni, C.3
  • 38
    • 0018223876 scopus 로고
    • Serum enzymes in human and experimental diabetes mellitus
    • Begum N, Sam GP, Shanmugasundaram KR. Serum enzymes in human and experimental diabetes mellitus. Indian J Med Res 1978;68:774-784.
    • (1978) Indian J Med Res , vol.68 , pp. 774-784
    • Begum, N.1    Sam, G.P.2    Shanmugasundaram, K.R.3
  • 39
    • 0016795414 scopus 로고
    • The stimulation of liver phosphorylase b by AMP, fluoride and sulfate. A technical note of the specific determination of the a and b forms of liver glycogen phosphorylase
    • Stallman W, Hers HG. The stimulation of liver phosphorylase b by AMP, fluoride and sulfate. A technical note of the specific determination of the a and b forms of liver glycogen phosphorylase. Eur J Biochem 1975;54:341-350.
    • (1975) Eur J Biochem , vol.54 , pp. 341-350
    • Stallman, W.1    Hers, H.G.2
  • 40
    • 0020659674 scopus 로고
    • Direct determination of inorganic phosphorus in serum with a single reagent
    • Munoz MA, Balon M, Fernandez C. Direct determination of inorganic phosphorus in serum with a single reagent. Clin Chem 1983;29:372-374.
    • (1983) Clin Chem , vol.29 , pp. 372-374
    • Munoz, M.A.1    Balon, M.2    Fernandez, C.3
  • 41
    • 0015366343 scopus 로고
    • Improved determination of serum total lipids by the sulpho-phospho-vanillin reaction
    • Frings CS, Frendley TW, Dunn RT, Queen CA. Improved determination of serum total lipids by the sulpho-phospho-vanillin reaction. Clin Chem 1972;18(7):673-674.
    • (1972) Clin Chem , vol.18 , Issue.7 , pp. 673-674
    • Frings, C.S.1    Frendley, T.W.2    Dunn, R.T.3    Queen, C.A.4
  • 42
    • 0019949179 scopus 로고
    • Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide
    • Fossati P, Prencipe L. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 1982;28(1):2077-2080.
    • (1982) Clin Chem , vol.28 , Issue.1 , pp. 2077-2080
    • Fossati, P.1    Prencipe, L.2
  • 44
    • 0014876627 scopus 로고
    • Rapid method for isolation of lipoprotein from human serum with polyanions
    • Burnstein M, Selvenick HR, Morfin R. Rapid method for isolation of lipoprotein from human serum with polyanions. J Lipid Res 1970;11:583-395.
    • (1970) J Lipid Res , vol.11 , pp. 583-395
    • Burnstein, M.1    Selvenick, H.R.2    Morfin, R.3
  • 45
    • 0016644375 scopus 로고
    • Indirect assessment of hydroxymethylglutaryl CoA reductase (NADPH) activity in liver tissue
    • Venugopala Rao A, Ramakrishan S. Indirect assessment of hydroxymethylglutaryl CoA reductase (NADPH) activity in liver tissue. Clin Chem 1975;21(10):1523-1525.
    • (1975) Clin Chem , vol.21 , Issue.10 , pp. 1523-1525
    • Venugopala Rao, A.1    Ramakrishan, S.2
  • 46
    • 0015348189 scopus 로고
    • Estimation of concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge
    • Friedewald WT. Estimation of concentration of low-density lipoprotein cholesterol in plasma without use of the preparative ultracentrifuge. Clin Chem 1972;18(7):499-502.
    • (1972) Clin Chem , vol.18 , Issue.7 , pp. 499-502
    • Friedewald, W.T.1
  • 48
    • 0031948697 scopus 로고    scopus 로고
    • Comparative effects of chromium, vanadium and gymnema sylvestre on sugar-induced blood pressure elevations in SHR
    • Preuss HG, Jarrel ST, Scheckenbach R, Lieberman S, Anderson RA. Comparative effects of chromium, vanadium and gymnema sylvestre on sugar-induced blood pressure elevations in SHR. J Am Coll Nutr 1998;17(2):116-123.
    • (1998) J Am Coll Nutr , vol.17 , Issue.2 , pp. 116-123
    • Preuss, H.G.1    Jarrel, S.T.2    Scheckenbach, R.3    Lieberman, S.4    Anderson, R.A.5
  • 49
    • 73649194769 scopus 로고
    • Improved method for determination of blood glutathione
    • Beutler E, Duron O, Kelly BM. Improved method for determination of blood glutathione. J Lab Clin Med 1963;61:882-888.
    • (1963) J Lab Clin Med , vol.61 , pp. 882-888
    • Beutler, E.1    Duron, O.2    Kelly, B.M.3
  • 50
    • 0022655274 scopus 로고
    • Intracellular and extracellular sulph-hydryl levels in rheumatoid arthritis
    • Koster JF, Biermond P, Swaak AJG. Intracellular and extracellular sulph-hydryl levels in rheumatoid arthritis. Ann Rheum Dis 1986;45:44-46.
    • (1986) Ann Rheum Dis , vol.45 , pp. 44-46
    • Koster, J.F.1    Biermond, P.2    Swaak, A.J.G.3
  • 51
    • 0014756187 scopus 로고
    • Measurement of catalase activity in tissue extracts
    • Cohen G, Dembiec D, Marcus J. Measurement of catalase activity in tissue extracts. Anal Biochem 1970;34:30-38.
    • (1970) Anal Biochem , vol.34 , pp. 30-38
    • Cohen, G.1    Dembiec, D.2    Marcus, J.3
  • 52
    • 0000379882 scopus 로고
    • Catalase, peroxidase and polyphenoloxidase activities during rice leaf senescence
    • Kar M, Mishra D. Catalase, peroxidase and polyphenoloxidase activities during rice leaf senescence. Plant Physiol 1976;57:315-319.
    • (1976) Plant Physiol , vol.57 , pp. 315-319
    • Kar, M.1    Mishra, D.2
  • 53
    • 0014300260 scopus 로고
    • Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro
    • Howell SL, Taylor KW. Potassium ions and the secretion of insulin by islets of Langerhans incubated in vitro. Biochem J 1968;108:17-24.
    • (1968) Biochem J , vol.108 , pp. 17-24
    • Howell, S.L.1    Taylor, K.W.2
  • 54
    • 0021150914 scopus 로고
    • Stimulation of insulin secretion from isolated rat islets of Langerhans by melittin
    • Morgan NG, Montague W. Stimulation of insulin secretion from isolated rat islets of Langerhans by melittin. Biosci Rep 1984;4:665-671.
    • (1984) Biosci Rep , vol.4 , pp. 665-671
    • Morgan, N.G.1    Montague, W.2
  • 55
    • 0025049979 scopus 로고
    • Hypoglycemic action of Salvia lavandulifolia vahl. ssp. Oxyodon: A contribution to studies on the mechanism of action
    • Zarzuelo A, Risco S, Gamez MJ, Jimenez J, Camara M, Martinez MA. Hypoglycemic action of Salvia lavandulifolia vahl. ssp. Oxyodon: a contribution to studies on the mechanism of action. Life Sci 1990;47:909-915.
    • (1990) Life Sci , vol.47 , pp. 909-915
    • Zarzuelo, A.1    Risco, S.2    Gamez, M.J.3    Jimenez, J.4    Camara, M.5    Martinez, M.A.6
  • 56
    • 3142778353 scopus 로고    scopus 로고
    • Separate isolation of genomic DNA and total RNA from single samples using the SV Total RNA Isolation System
    • Otto P, Kephart D, Bitner R, Huber S, Volkerding K. Separate isolation of genomic DNA and total RNA from single samples using the SV Total RNA Isolation System. Promega Notes 1998;69:19-23.
    • (1998) Promega Notes , vol.69 , pp. 19-23
    • Otto, P.1    Kephart, D.2    Bitner, R.3    Huber, S.4    Volkerding, K.5
  • 58
    • 0020494488 scopus 로고
    • Antidiabetic effect of (-)-epicatechin
    • Chakravarthy BK, Gupta S, Gode KD. Antidiabetic effect of (-)-epicatechin. Lancet 1982;1:272-273.
    • (1982) Lancet , vol.1 , pp. 272-273
    • Chakravarthy, B.K.1    Gupta, S.2    Gode, K.D.3
  • 59
    • 0020455417 scopus 로고
    • Functional beta cell regeneration in the islets of pancreas in alloxan induced diabetic rats by (-)-epicatechin
    • Chakravarthy BK, Gupta S, Gode KD. Functional beta cell regeneration in the islets of pancreas in alloxan induced diabetic rats by (-)-epicatechin. Life Sci 1982;31:2693-2697.
    • (1982) Life Sci , vol.31 , pp. 2693-2697
    • Chakravarthy, B.K.1    Gupta, S.2    Gode, K.D.3
  • 60
    • 0027074281 scopus 로고
    • The efficacy of quercetin in alloxan diabetes
    • Nuraliev IN, Avezov GA. The efficacy of quercetin in alloxan diabetes. Exp Clin Pharmacol 1992;55:42-44.
    • (1992) Exp Clin Pharmacol , vol.55 , pp. 42-44
    • Nuraliev, I.N.1    Avezov, G.A.2
  • 61
    • 0037531830 scopus 로고    scopus 로고
    • Effects of Teucrium polium on oral glucose tolerance test, regeneration of pancreatic islets and activity of hepatic glucokinase in diabetic rats
    • Vessal M, Zal F, Vasi M. Effects of Teucrium polium on oral glucose tolerance test, regeneration of pancreatic islets and activity of hepatic glucokinase in diabetic rats. Arch Iran Med 2003;6:36-39.
    • (2003) Arch Iran Med , vol.6 , pp. 36-39
    • Vessal, M.1    Zal, F.2    Vasi, M.3
  • 62
    • 0024398947 scopus 로고
    • Medicinal plants with hypoglycemic activity
    • Atta-Ur-Rahman, Zaman K. Medicinal plants with hypoglycemic activity. J Ethnopharmacol 1989;26:1-55.
    • (1989) J Ethnopharmacol , vol.26 , pp. 1-55
    • Atta-Ur-Rahman1    Zaman, K.2
  • 64
    • 0028835878 scopus 로고
    • Antidiabetic plants and their active constituents
    • Marles RJ, Farnsworth NR. Antidiabetic plants and their active constituents. Phytomedicine 1995;2(2):137-189.
    • (1995) Phytomedicine , vol.2 , Issue.2 , pp. 137-189
    • Marles, R.J.1    Farnsworth, N.R.2
  • 65
    • 0345567910 scopus 로고
    • The hypoglycemic effect of volatile oil of some Egyptian plants
    • Essawy GS, Sobbhy HM, El-Banna HA. The hypoglycemic effect of volatile oil of some Egyptian plants. Vet Med J (Giza) 1995;43(2):167-172.
    • (1995) Vet Med J (Giza) , vol.43 , Issue.2 , pp. 167-172
    • Essawy, G.S.1    Sobbhy, H.M.2    El-Banna, H.A.3
  • 66
    • 1042292667 scopus 로고    scopus 로고
    • Antidiabetic activity of Zingiber officinale in streptozotocin-induced type 1 diabetic rats
    • Akhani SP, Vishwakarma SL, Goyal RK. Antidiabetic activity of Zingiber officinale in streptozotocin-induced type 1 diabetic rats. J Pharm Pharmacol 2004;56(1):101-105.
    • (2004) J Pharm Pharmacol , vol.56 , Issue.1 , pp. 101-105
    • Akhani, S.P.1    Vishwakarma, S.L.2    Goyal, R.K.3
  • 67
    • 0033918336 scopus 로고    scopus 로고
    • Individual and combined antioxidant effects of seven phenolic agents in human erythrocyte membrane ghosts and phosphatidylcholine liposome systems: Importance of the partition coefficient
    • Liao K, Yin M. Individual and combined antioxidant effects of seven phenolic agents in human erythrocyte membrane ghosts and phosphatidylcholine liposome systems: importance of the partition coefficient. J Agric Food Chem 2000;48:2266-2270.
    • (2000) J Agric Food Chem , vol.48 , pp. 2266-2270
    • Liao, K.1    Yin, M.2
  • 68
    • 11144328863 scopus 로고    scopus 로고
    • Quercetin, a flavonoid antoxidant, prevents and protects streptozotocin induced oxidative stress and a-cell damage in rat pancreas
    • Coskun OM, Kanter A, Korkmaz, SO. Quercetin, a flavonoid antoxidant, prevents and protects streptozotocin induced oxidative stress and a-cell damage in rat pancreas. Pharmacol Res 2005;51:117-123.
    • (2005) Pharmacol Res , vol.51 , pp. 117-123
    • Coskun, O.M.1    Kanter, A.2    Korkmaz, S.O.3
  • 69
    • 0022384509 scopus 로고
    • Effects of flavonoids on insulin secretion and Ca+2 handling in rat islets of Langerhans
    • Hii CST, Howell SL. Effects of flavonoids on insulin secretion and Ca+2 handling in rat islets of Langerhans. J Endocrinol 1985;107:1-8.
    • (1985) J Endocrinol , vol.107 , pp. 1-8
    • Hii, C.S.T.1    Howell, S.L.2
  • 70
    • 0022647492 scopus 로고
    • Serum fructosamine and glycated hemoglobin measurements in diabetic control
    • Hindle EJ, Rostron GM, Clarck SA, Catt JA. Serum fructosamine and glycated hemoglobin measurements in diabetic control. Arch Dis Childhood 1986;61:113-117.
    • (1986) Arch Dis Childhood , vol.61 , pp. 113-117
    • Hindle, E.J.1    Rostron, G.M.2    Clarck, S.A.3    Catt, J.A.4
  • 71
    • 77951239705 scopus 로고    scopus 로고
    • Carbohydrates and alterations in glucose metabolism
    • In: Bishop ML, Fody EP, editors, Philadelphia: Lippincott
    • Donnelly JG. Carbohydrates and alterations in glucose metabolism. In: Bishop ML, Fody EP, editors. Clinical chemistry (principles, procedures, correlations). Philadelphia: Lippincott, 1996; pp. 308-309.
    • (1996) Clinical Chemistry (Principles, Procedures, Correlations) , pp. 308-309
    • Donnelly, J.G.1
  • 72
    • 15844366271 scopus 로고    scopus 로고
    • Involvement of hydrogen peroxide in collagen cross-linking by high glucose in vitro and in vivo
    • Elgawish A, Glomb M, Freelander M, Monnier VM. Involvement of hydrogen peroxide in collagen cross-linking by high glucose in vitro and in vivo. J Biol Chem 1996;271:12964-12971.
    • (1996) J Biol Chem , vol.271 , pp. 12964-12971
    • Elgawish, A.1    Glomb, M.2    Freelander, M.3    Monnier, V.M.4
  • 73
    • 0033712738 scopus 로고    scopus 로고
    • Antihyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism
    • Grover JK, Vats V, Rathi SS. Antihyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-470.
    • (2000) J Ethnopharmacol , vol.73 , pp. 461-470
    • Grover, J.K.1    Vats, V.2    Rathi, S.S.3
  • 74
    • 0034740870 scopus 로고    scopus 로고
    • Trigonella foenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reserving the altered glycolytic, gluconeogenic and lipogenic enzymes
    • Raju J, Gupta D, Rao AR, Yadava PK, Baquer NZ. Trigonella foenum graecum (fenugreek) seed powder improves glucose homeostasis in alloxan diabetic rat tissues by reserving the altered glycolytic, gluconeogenic and lipogenic enzymes. Mol Cell Biochem 2001;224(1-2):45-51.
    • (2001) Mol Cell Biochem , vol.224 , Issue.1-2 , pp. 45-51
    • Raju, J.1    Gupta, D.2    Rao, A.R.3    Yadava, P.K.4    Baquer, N.Z.5
  • 75
    • 0026040527 scopus 로고
    • Hormone-stimulated glucose production from glycogen in hepatocytes from streptozotocin diabetic rats
    • Lavoie L, Van de Werve G. Hormone-stimulated glucose production from glycogen in hepatocytes from streptozotocin diabetic rats. Metabolism 1991;40(10):1031-1036.
    • (1991) Metabolism , vol.40 , Issue.10 , pp. 1031-1036
    • Lavoie, L.1    van de Werve, G.2
  • 76
    • 77951225022 scopus 로고    scopus 로고
    • The hypoglycemic effect of curcumin and esculetin and their probable mechanisms of action in streptozotocin diabetic albino rats
    • Ahmed OM. The hypoglycemic effect of curcumin and esculetin and their probable mechanisms of action in streptozotocin diabetic albino rats. J Egypt Ger Soc Zool 2005;46(A):351-375.
    • (2005) J Egypt Ger Soc Zool , vol.46 , Issue.A , pp. 351-375
    • Ahmed, O.M.1
  • 77
    • 70949101022 scopus 로고    scopus 로고
    • Studies on the hypoglycemic and hypolipidemic effects of glimepiride and some antidiabetic plants on streptozotocin diabetic rats
    • Abdel-Moneim A, Ahmed OM, Rawi SM, Semmler M. Studies on the hypoglycemic and hypolipidemic effects of glimepiride and some antidiabetic plants on streptozotocin diabetic rats. J Egypt Ger Soc Zool 2001;34(A):175-206.
    • (2001) J Egypt Ger Soc Zool , vol.34 , Issue.A , pp. 175-206
    • Abdel-Moneim, A.1    Ahmed, O.M.2    Rawi, S.M.3    Semmler, M.4
  • 78
    • 77951210505 scopus 로고    scopus 로고
    • Evaluation of the antihyperglycemic, antihyperlipidemic and myocardial enhancing properties of pioglitazone in diabetic and hyperthyroid rats
    • Ahmed OM. Evaluation of the antihyperglycemic, antihyperlipidemic and myocardial enhancing properties of pioglitazone in diabetic and hyperthyroid rats. J Egypt Ger Soc Zool 2006;51(A):253-278.
    • (2006) J Egypt Ger Soc Zool , vol.51 , Issue.A , pp. 253-278
    • Ahmed, O.M.1
  • 79
    • 0032533162 scopus 로고    scopus 로고
    • Specific features of glycogen metabolism in the liver
    • Bollen M, Keppens S, Stalmans W. Specific features of glycogen metabolism in the liver. Biochem J 1998;336:19-31.
    • (1998) Biochem J , vol.336 , pp. 19-31
    • Bollen, M.1    Keppens, S.2    Stalmans, W.3
  • 80
    • 0030973757 scopus 로고    scopus 로고
    • Glucoseinduced glycogenesis in the liver involves the glucose-6-phosphate-dependent phosphorylation of glycogen synthase
    • Cadefau J, Bollen M, Stalmans W. Glucoseinduced glycogenesis in the liver involves the glucose-6-phosphate-dependent phosphorylation of glycogen synthase. Biochem J 1997;322(3):745-750.
    • (1997) Biochem J , vol.322 , Issue.3 , pp. 745-750
    • Cadefau, J.1    Bollen, M.2    Stalmans, W.3
  • 81
    • 0029054019 scopus 로고
    • Direct stimulation of myocardial glucose transport and glucose transporter-1 (GLUT1) and GLUT4 protein expression by the sulfonylurea glimepiride
    • Bahr M, Von Holty M, Muller G, Eckel J. Direct stimulation of myocardial glucose transport and glucose transporter-1 (GLUT1) and GLUT4 protein expression by the sulfonylurea glimepiride. Endocrinology 1995;136:2547-2553.
    • (1995) Endocrinology , vol.136 , pp. 2547-2553
    • Bahr, M.1    von Holty, M.2    Muller, G.3    Eckel, J.4
  • 82
    • 0029091094 scopus 로고
    • Extrapancreatic effects of sulfonylureas - a comparison between glimepiride and conventional sulfonylureas
    • Muller G, Satoh Y, Geisen K. Extrapancreatic effects of sulfonylureas - a comparison between glimepiride and conventional sulfonylureas. Diabetes Res Clin Pract 1995;28(Suppl):115-137.
    • (1995) Diabetes Res Clin Pract , vol.28 , Issue.SUPPL. , pp. 115-137
    • Muller, G.1    Satoh, Y.2    Geisen, K.3
  • 83
    • 0036499692 scopus 로고    scopus 로고
    • A natural protective mechanism against hyperglycemia in vascular endothelial and smooth muscle cells: Role of glucose and 12-hydroxyeicosatetraenoic acid
    • Alpert E, Gruzman A, Totary H, Kaiser N, Reich R, Sasson S. A natural protective mechanism against hyperglycemia in vascular endothelial and smooth muscle cells: role of glucose and 12-hydroxyeicosatetraenoic acid. Biochem J 2002;362:413-422.
    • (2002) Biochem J , vol.362 , pp. 413-422
    • Alpert, E.1    Gruzman, A.2    Totary, H.3    Kaiser, N.4    Reich, R.5    Sasson, S.6
  • 84
    • 12744279669 scopus 로고    scopus 로고
    • Diabetes, insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage
    • Raz I, Eldor R, Cernea S, Shafrir E. Diabetes, insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage. Diabetes Metab Res Rev 2005;21:3-14.
    • (2005) Diabetes Metab Res Rev , vol.21 , pp. 3-14
    • Raz, I.1    Eldor, R.2    Cernea, S.3    Shafrir, E.4
  • 85
    • 33645892889 scopus 로고    scopus 로고
    • Effect of citrus? Avonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice
    • Jung UJ, Lee MK, Park YB, Kang MA., Choia MS. Effect of citrus? Avonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice. Int J Biochem Cell Biol 2006;38:1134-1145.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 1134-1145
    • Jung, U.J.1    Lee, M.K.2    Park, Y.B.3    Kang, M.A.4    Choia, M.S.5
  • 87
    • 0037900979 scopus 로고    scopus 로고
    • Minireview: Lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors
    • Lee CH, Olson P, Evans RM. Minireview: lipid metabolism, metabolic diseases, and peroxisome proliferator-activated receptors. Endocrinology 2003;144:2201-2207.
    • (2003) Endocrinology , vol.144 , pp. 2201-2207
    • Lee, C.H.1    Olson, P.2    Evans, R.M.3
  • 88
    • 23644456172 scopus 로고    scopus 로고
    • Therapeutic roles of peroxisome proliferator-activated receptor agonists
    • Staels B, Fruchart JC. Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 2005;54:2460-2470.
    • (2005) Diabetes , vol.54 , pp. 2460-2470
    • Staels, B.1    Fruchart, J.C.2
  • 89
    • 32644460092 scopus 로고    scopus 로고
    • From molecular action to physiological outputs: Peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions
    • Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W. From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions. Prog Lipid Res 2006;45:120-159.
    • (2006) Prog Lipid Res , vol.45 , pp. 120-159
    • Feige, J.N.1    Gelman, L.2    Michalik, L.3    Desvergne, B.4    Wahli, W.5
  • 90
    • 33644652183 scopus 로고    scopus 로고
    • Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis
    • Lefebvre P, Chinetti G, Fruchart JC, Staels B. Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis. J Clin Invest 2006;116:571-580.
    • (2006) J Clin Invest , vol.116 , pp. 571-580
    • Lefebvre, P.1    Chinetti, G.2    Fruchart, J.C.3    Staels, B.4
  • 91
    • 0029859494 scopus 로고
    • Troglitazone inhibits fatty acid oxidation and esterification, and gluconeogenesis in isolated hepatocytes from starved rats
    • Fulgencio JP, Kohl C, Girard J, Pegorier JP. Troglitazone inhibits fatty acid oxidation and esterification, and gluconeogenesis in isolated hepatocytes from starved rats. Diabetes 1995;45:1556-1562.
    • (1995) Diabetes , vol.45 , pp. 1556-1562
    • Fulgencio, J.P.1    Kohl, C.2    Girard, J.3    Pegorier, J.P.4
  • 92
    • 0035798713 scopus 로고    scopus 로고
    • The mechanisms by which both heterozygous peroxisome proliferatoractivated receptor gamma (PPARγ) deficiency and PPARγ agonist improve insulin resistance
    • Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K. The mechanisms by which both heterozygous peroxisome proliferatoractivated receptor gamma (PPARγ) deficiency and PPARγ agonist improve insulin resistance. J Biol Chem 2001;276:41245-41254.
    • (2001) J Biol Chem , vol.276 , pp. 41245-41254
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Murakami, K.4    Motojima, K.5    Komeda, K.6
  • 93
    • 0842307302 scopus 로고    scopus 로고
    • Liver glucokinase can be activated by peroxisome proliferator-activated receptor-γ
    • Kim SY, Kim HI, Park SK, Im SS, Li T, Cheon HG. Liver glucokinase can be activated by peroxisome proliferator-activated receptor-γ. Diabetes 2004;53:S66-S70.
    • (2004) Diabetes , vol.53
    • Kim, S.Y.1    Kim, H.I.2    Park, S.K.3    Im, S.S.4    Li, T.5    Cheon, H.G.6
  • 94
    • 0032913601 scopus 로고    scopus 로고
    • Combination treatment with troglitazone, an insulin action enhancer, and pravastatin, an inhibitor of HMG-CoA reductase, shows a synergistic effect on atherosclerosis in WHHL rabbits
    • Shiomi M, Ito T, Tsukada T, Tsujita Y, Horikoshi H. Combination treatment with troglitazone, an insulin action enhancer, and pravastatin, an inhibitor of HMG-CoA reductase, shows a synergistic effect on atherosclerosis in WHHL rabbits. Atherosclerosis 1999;142:345-353.
    • (1999) Atherosclerosis , vol.142 , pp. 345-353
    • Shiomi, M.1    Ito, T.2    Tsukada, T.3    Tsujita, Y.4    Horikoshi, H.5
  • 97
    • 13544252637 scopus 로고    scopus 로고
    • Upregulation of GLUT-4 and PPARγ by an isoflavone from Pterocarpus marsupium on L6 myotubes: A possible mechanism of action
    • Anandharajan R, Pathmanathan K, Shankernarayanan NP, Ram AV, Arun B. Upregulation of GLUT-4 and PPARγ by an isoflavone from Pterocarpus marsupium on L6 myotubes: a possible mechanism of action. J Ethnopharmacol 2005;97:253-260.
    • (2005) J Ethnopharmacol , vol.97 , pp. 253-260
    • Anandharajan, R.1    Pathmanathan, K.2    Shankernarayanan, N.P.3    Ram, A.V.4    Arun, B.5
  • 98
    • 39149143637 scopus 로고    scopus 로고
    • Adipokines: The missing link between insulin resistance and obesity
    • Antuna-Puente B, Feve B, Fellahi S, Bastard JP. Adipokines: the missing link between insulin resistance and obesity. Diab Metabol 2008;34:2-11.
    • (2008) Diab Metabol , vol.34 , pp. 2-11
    • Antuna-Puente, B.1    Feve, B.2    Fellahi, S.3    Bastard, J.P.4


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