Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation

Liver International

Volumn 33, Issue 7, 2013, Pages 1056-1061

  Bieghs, Veerle ^a,b   Walenbergh, Sofie M A ^a   Hendrikx, Tim ^a   van Gorp, Patrick J ^a   Verheyen, Fons ^a   Olde Damink, Steven W ^a,c   Masclee, Ad A ^d   Koek, Ger H ^d   Hofker, Marten H ^e   Binder, Christoph J ^f,g   Shiri Sverdlov, Ronit ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^f MEDICAL UNIVERSITY OF VIENNA   (Austria)

^g ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

Inflammation; Kupffer cells; Liver; Lysosomes; OxLDL

Indexed keywords

ACETYL LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN; SCAVENGER RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; HEPATITIS; KUPFFER CELL; LIVER HISTOLOGY; LYSOSOME; MOUSE; NONHUMAN;

INFLAMMATION; KUPFFER CELLS; LIVER; LYSOSOMES; OXLDL;

ANIMALS; DNA PRIMERS; FATTY LIVER; KUPFFER CELLS; LIPOPROTEINS, LDL; LYSOSOMES; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION;

EID: 84880178234     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12170     Document Type: Article

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