메뉴 건너뛰기




Volumn 133, Issue 2, 1997, Pages 153-161

The toxicity to macrophages of oxidized low-density lipoprotein is mediated through lysosomal damage

Author keywords

Atherosclerosis; Cytotoxicity; Low density lipoprotein oxidation; Lysosomes; Macrophages; Oxidative stress

Indexed keywords

COPPER; OXIDIZED LOW DENSITY LIPOPROTEIN;

EID: 0001712708     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(97)00094-4     Document Type: Article
Times cited : (54)

References (52)
  • 1
    • 0026696680 scopus 로고
    • Cellular damage in mouse peritoneal macrophages exposed to cholesteryl linoleate
    • Reid V.C., Brabbs C.E., Mitchinson M.J. Cellular damage in mouse peritoneal macrophages exposed to cholesteryl linoleate. Atherosclerosis. 92:1992;251-260.
    • (1992) Atherosclerosis , vol.92 , pp. 251-260
    • Reid, V.C.1    Brabbs, C.E.2    Mitchinson, M.J.3
  • 2
    • 0027525873 scopus 로고
    • Toxicity of oxidised low density lipoprotein towards mouse peritoneal macrophages in vitro
    • Reid V.C., Mitchinson M.J. Toxicity of oxidised low density lipoprotein towards mouse peritoneal macrophages in vitro. Atherosclerosis. 98:1993;17-24.
    • (1993) Atherosclerosis , vol.98 , pp. 17-24
    • Reid, V.C.1    Mitchinson, M.J.2
  • 3
    • 0027340426 scopus 로고
    • Fragmentation of DNA in P338D1 macrophages exposed to oxidised low-density lipoprotein
    • Reid V.C., Hardwick S.J., Mitchinson M.J. Fragmentation of DNA in P338D1 macrophages exposed to oxidised low-density lipoprotein. FEBS Lett. 332:1993;218-220.
    • (1993) FEBS Lett , vol.332 , pp. 218-220
    • Reid, V.C.1    Hardwick, S.J.2    Mitchinson, M.J.3
  • 5
    • 0028821453 scopus 로고
    • Oxidized low-density lipoprotein is cytotoxic to human monocyte-macrophages: Protection with lipophilic antioxidants
    • Marchant C.E., Law N.S., Veen C.V.D., Hardwick S.J., Carpenter K.L.H., Mitchinson M.J. Oxidized low-density lipoprotein is cytotoxic to human monocyte-macrophages: protection with lipophilic antioxidants. FEBS Lett. 358:1995;175-178.
    • (1995) FEBS Lett , vol.358 , pp. 175-178
    • Marchant, C.E.1    Law, N.S.2    Veen, C.V.D.3    Hardwick, S.J.4    Carpenter, K.L.H.5    Mitchinson, M.J.6
  • 6
    • 0022407980 scopus 로고
    • Induction of macrophage growth by the lipid moiety of lipoprotein and its augmentation by denaturation of the lipoproteins
    • Yui S., Mizuno D., Yamazaki M. Induction of macrophage growth by the lipid moiety of lipoprotein and its augmentation by denaturation of the lipoproteins. J Leukocyte Biol. 38:1985;697-707.
    • (1985) J Leukocyte Biol , vol.38 , pp. 697-707
    • Yui, S.1    Mizuno, D.2    Yamazaki, M.3
  • 7
    • 0022635111 scopus 로고
    • Induction of macrophage growth by lipids
    • Yui S., Yamazaki M. Induction of macrophage growth by lipids. J Immunol. 136:1986;1334-1338.
    • (1986) J Immunol , vol.136 , pp. 1334-1338
    • Yui, S.1    Yamazaki, M.2
  • 8
    • 0025092037 scopus 로고
    • Augmentation of macrophage growth-stimulating activity of lipids by their peroxidation
    • Yui S., Yamazaki M. Augmentation of macrophage growth-stimulating activity of lipids by their peroxidation. J Immunol. 144:1990;1466-1471.
    • (1990) J Immunol , vol.144 , pp. 1466-1471
    • Yui, S.1    Yamazaki, M.2
  • 11
    • 0028079980 scopus 로고
    • Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages
    • Sakai M., Miyazaki A., Hakamata H., Sasaki T., Yui S., Yamazaki M., Shichiri M., Horiuchi S. Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages. J Biol Chem. 269:1994;31430-31435.
    • (1994) J Biol Chem , vol.269 , pp. 31430-31435
    • Sakai, M.1    Miyazaki, A.2    Hakamata, H.3    Sasaki, T.4    Yui, S.5    Yamazaki, M.6    Shichiri, M.7    Horiuchi, S.8
  • 14
    • 0029991376 scopus 로고    scopus 로고
    • Oxidized low density lipoproteins alter macrophage lipid uptake, apoptosis, viability and nitric oxide synthesis
    • Yang X., Galeano N.F., Szabolcs M., Sciacca R.R., Cannon P.J. Oxidized low density lipoproteins alter macrophage lipid uptake, apoptosis, viability and nitric oxide synthesis. J Nutr. 126:1996;1072S-1075S.
    • (1996) J Nutr , vol.126
    • Yang, X.1    Galeano, N.F.2    Szabolcs, M.3    Sciacca, R.R.4    Cannon, P.J.5
  • 15
    • 0028267140 scopus 로고
    • Induction of macrophage growth by advanced glycation end products of the Maillard reaction
    • Yui S., Sasaki T., Araki N., Horiuchi S., Yamazaki M. Induction of macrophage growth by advanced glycation end products of the Maillard reaction. J Immunol. 152:1994;1943-1949.
    • (1994) J Immunol , vol.152 , pp. 1943-1949
    • Yui, S.1    Sasaki, T.2    Araki, N.3    Horiuchi, S.4    Yamazaki, M.5
  • 16
    • 0029948866 scopus 로고    scopus 로고
    • Induction of human endothelial cell growth by mildly oxidized low density lipoprotein
    • Maier J.A.M., Barenghi L., Bradamante S., Pagani F. Induction of human endothelial cell growth by mildly oxidized low density lipoprotein. Atherosclerosis. 123:1996;115-121.
    • (1996) Atherosclerosis , vol.123 , pp. 115-121
    • Maier, J.A.M.1    Barenghi, L.2    Bradamante, S.3    Pagani, F.4
  • 17
    • 0026059831 scopus 로고
    • Lipid peroxides and transition metals are required for the toxicity of oxidized low density lipoprotein to cultured endothelial cells
    • Kuzuya M., Naito M., Funaki C., Hayashi T., Asai K., Kuzuya F. Lipid peroxides and transition metals are required for the toxicity of oxidized low density lipoprotein to cultured endothelial cells. Biochim Biophys Acta. 1096:1991;155-161.
    • (1991) Biochim Biophys Acta , vol.1096 , pp. 155-161
    • Kuzuya, M.1    Naito, M.2    Funaki, C.3    Hayashi, T.4    Asai, K.5    Kuzuya, F.6
  • 18
    • 0027518468 scopus 로고
    • In situ immunolocalization of lipoproteins in human arteriosclerotic tissue
    • Kaesberg B., Harrach B., Dieplinger H., Robenek H. In situ immunolocalization of lipoproteins in human arteriosclerotic tissue. Arterioscler Thromb. 13:1993;133-146.
    • (1993) Arterioscler Thromb , vol.13 , pp. 133-146
    • Kaesberg, B.1    Harrach, B.2    Dieplinger, H.3    Robenek, H.4
  • 20
    • 0026748405 scopus 로고
    • The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophages
    • Jessup W., Mander E.L., Dean R.T. The intracellular storage and turnover of apolipoprotein B of oxidized LDL in macrophages. Biochim Biophys Acta. 1126:1992;167-177.
    • (1992) Biochim Biophys Acta , vol.1126 , pp. 167-177
    • Jessup, W.1    Mander, E.L.2    Dean, R.T.3
  • 21
    • 0023187835 scopus 로고
    • Flow cytofluorometry of lysosomal acridine orange uptake by living cultured cells. Effect of trypsinization and starvation
    • Olsson M., Rundquist I., Brunk U. Flow cytofluorometry of lysosomal acridine orange uptake by living cultured cells. Effect of trypsinization and starvation. Acta Pathol Microbiol Immunol Scand A. 95:1987;159-165.
    • (1987) Acta Pathol Microbiol Immunol Scand a , vol.95 , pp. 159-165
    • Olsson, M.1    Rundquist, I.2    Brunk, U.3
  • 22
    • 0001313069 scopus 로고
    • Lethal hydrogen peroxide toxicity involves lysosomal iron-catalyzed reactions with membrane damage
    • Brunk U.T., Zhang H., Öllinger K. Lethal hydrogen peroxide toxicity involves lysosomal iron-catalyzed reactions with membrane damage. Redox Rep. 1:1995;267-277.
    • (1995) Redox Rep , vol.1 , pp. 267-277
    • Brunk, U.T.1    Zhang, H.2    Öllinger, K.3
  • 23
    • 0028821967 scopus 로고
    • Exposure of cells to nonlethal concentrations of hydrogen peroxide induces degeneration-repair mechanisms involving lysosomal destabilization
    • Brunk U.T., Zhang H., Dalen H., Öllinger K. Exposure of cells to nonlethal concentrations of hydrogen peroxide induces degeneration-repair mechanisms involving lysosomal destabilization. Free Radic Biol Med. 19:1995;813-822.
    • (1995) Free Radic Biol Med , vol.19 , pp. 813-822
    • Brunk, U.T.1    Zhang, H.2    Dalen, H.3    Öllinger, K.4
  • 24
    • 0014025220 scopus 로고
    • Fluorescence microscopy of lysosome and related structures in living cells
    • Zelenin A.V. Fluorescence microscopy of lysosome and related structures in living cells. Nature. 212:1966;425-426.
    • (1966) Nature , vol.212 , pp. 425-426
    • Zelenin, A.V.1
  • 25
    • 0023841862 scopus 로고
    • A view of acidic intracellular compartments
    • Anderson R.G.W., Orci L. A view of acidic intracellular compartments. J Cell Biol. 106:1988;539-543.
    • (1988) J Cell Biol , vol.106 , pp. 539-543
    • Anderson, R.G.W.1    Orci, L.2
  • 26
    • 33745026603 scopus 로고
    • The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
    • Havel R.J., Eder H.A., Bragdon J.H. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest. 34:1955;1345-1353.
    • (1955) J Clin Invest , vol.34 , pp. 1345-1353
    • Havel, R.J.1    Eder, H.A.2    Bragdon, J.H.3
  • 27
    • 0024584235 scopus 로고
    • A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent
    • El-Saadani M., Esterbauer H., El-Sayed M., Goher M., Nassar A.Y., Jürgens G. A spectrophotometric assay for lipid peroxides in serum lipoproteins using a commercially available reagent. J Lipid Res. 30:1989;627-630.
    • (1989) J Lipid Res , vol.30 , pp. 627-630
    • El-Saadani, M.1    Esterbauer, H.2    El-Sayed, M.3    Goher, M.4    Nassar, A.Y.5    Jürgens, G.6
  • 28
    • 0017065248 scopus 로고
    • A simple fluorometric assay for lipoperoxides in blood plasma
    • Yagi K. A simple fluorometric assay for lipoperoxides in blood plasma. Biochem Res. 15:1976;212-216.
    • (1976) Biochem Res , vol.15 , pp. 212-216
    • Yagi, K.1
  • 29
    • 0023221153 scopus 로고
    • Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products
    • Steinbrecher U.P. Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products. J Biol Chem. 262:1987;3603-3608.
    • (1987) J Biol Chem , vol.262 , pp. 3603-3608
    • Steinbrecher, U.P.1
  • 30
    • 4243978507 scopus 로고
    • Isolation of lymphocytes, granulocytes, and macrophages
    • Böyum A. Isolation of lymphocytes, granulocytes, and macrophages. Scand J Immunol Suppl. 8:1968;5-15.
    • (1968) Scand J Immunol Suppl , vol.8 , pp. 5-15
    • Böyum, A.1
  • 31
    • 0018646905 scopus 로고
    • Pretreatment of plastic petri dishes with fetal calf serum. A simple method for macrophage's isolation
    • Kumagai K.K., Hinnuma S.I., Tada M. Pretreatment of plastic petri dishes with fetal calf serum. A simple method for macrophage's isolation. J Immunol Methods. 67:1979;17-25.
    • (1979) J Immunol Methods , vol.67 , pp. 17-25
    • Kumagai, K.K.1    Hinnuma, S.I.2    Tada, M.3
  • 32
    • 0026632822 scopus 로고
    • Effect of arterial proteoglycans and glycosaminoglycans on low density lipoprotein oxidation and its uptake by human macrophages and arterial smooth muscle cells
    • Hurt-Camejo E., Camejo G., Rosengren B., Lopez F., Ahlström C., Fager G., Bondjers G. Effect of arterial proteoglycans and glycosaminoglycans on low density lipoprotein oxidation and its uptake by human macrophages and arterial smooth muscle cells. Arterioscler Thromb. 12:1992;569-583.
    • (1992) Arterioscler Thromb , vol.12 , pp. 569-583
    • Hurt-Camejo, E.1    Camejo, G.2    Rosengren, B.3    Lopez, F.4    Ahlström, C.5    Fager, G.6    Bondjers, G.7
  • 33
    • 0018634771 scopus 로고
    • Trypan blue as a marker of plasma membrane permeability in alloxan-treated mouse islet cells
    • Grankvist K., Lernmark Å., Täljedal I.-B. Trypan blue as a marker of plasma membrane permeability in alloxan-treated mouse islet cells. J Endocrinol Invest. 2:1979;139-145.
    • (1979) J Endocrinol Invest , vol.2 , pp. 139-145
    • Grankvist, K.1    Lernmark, Å.2    Täljedal, I.-B.3
  • 34
    • 0029165943 scopus 로고
    • Effects of iron- And haemoglobin-loaded human monocyte-derived macrophages on oxidation and uptake of low density lipoprotein
    • Yuan X.M., Brunk U.T., Olsson A.G. Effects of iron- and haemoglobin-loaded human monocyte-derived macrophages on oxidation and uptake of low density lipoprotein. Arterioscler Thromb Vasc Biol. 15:1995;1345-1351.
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 1345-1351
    • Yuan, X.M.1    Brunk, U.T.2    Olsson, A.G.3
  • 35
    • 0343461864 scopus 로고    scopus 로고
    • Macrophage erythrophagocytosis and iron exocytosis
    • Yuan X.M., Olsson A.G., Brunk U.T. Macrophage erythrophagocytosis and iron exocytosis. Redox Rep. 2:1996;9-17.
    • (1996) Redox Rep , vol.2 , pp. 9-17
    • Yuan, X.M.1    Olsson, A.G.2    Brunk, U.T.3
  • 36
    • 0029941609 scopus 로고    scopus 로고
    • Iron in human atheroma and LDL oxidation by macrophages following erythrophagocytosis
    • Yuan X.M., Li W., Olsson A.G., Brunk U.T. Iron in human atheroma and LDL oxidation by macrophages following erythrophagocytosis. Atherosclerosis. 124:1996;61-73.
    • (1996) Atherosclerosis , vol.124 , pp. 61-73
    • Yuan, X.M.1    Li, W.2    Olsson, A.G.3    Brunk, U.T.4
  • 37
    • 0027135966 scopus 로고
    • Cytotoxicity of UV-oxidized LDL to cultured cells. A model system for studying the potential role of toxic events in atherosclerosis
    • Negre-Salvayre A, Salvayre R. Cytotoxicity of UV-oxidized LDL to cultured cells. A model system for studying the potential role of toxic events in atherosclerosis. J Photochem Photobiol B: Biol 1993;21:235-238.
    • (1993) J Photochem Photobiol B: Biol , vol.21 , pp. 235-238
    • Negre-Salvayre, A.1    Salvayre, R.2
  • 38
    • 0027409382 scopus 로고
    • Lethal damage to endothelial cells by oxidized low density lipoprotein: Role of selenoperoxidases in cytoprotection against lipid hydroperoxide- And iron-mediated reactions
    • Thomas J.P., Geiger P.G., Girotti A.W. Lethal damage to endothelial cells by oxidized low density lipoprotein: role of selenoperoxidases in cytoprotection against lipid hydroperoxide- and iron-mediated reactions. J Lipid Res. 34:1993;479-490.
    • (1993) J Lipid Res , vol.34 , pp. 479-490
    • Thomas, J.P.1    Geiger, P.G.2    Girotti, A.W.3
  • 39
    • 0027157403 scopus 로고
    • Protective effect of 17β-estradiol against the cytotoxicity of minimally oxidized LDL to cultured bovine aortic endothelial cells
    • Negre-Salvayre A., Pieraggi M.T., Mabile L., Salvayre R. Protective effect of 17β-estradiol against the cytotoxicity of minimally oxidized LDL to cultured bovine aortic endothelial cells. Atherosclerosis. 99:1993;207-217.
    • (1993) Atherosclerosis , vol.99 , pp. 207-217
    • Negre-Salvayre, A.1    Pieraggi, M.T.2    Mabile, L.3    Salvayre, R.4
  • 40
    • 0029125781 scopus 로고
    • Oxidizability and subsequent cytotoxicity of chylomicrons to monocytic U937 and endothelial cells are dependent on dietary fatty acid composition
    • Mabile L., Salvayre R., Bonnafe M.J., Negre-Salvayre A. Oxidizability and subsequent cytotoxicity of chylomicrons to monocytic U937 and endothelial cells are dependent on dietary fatty acid composition. Free Radic Biol Med. 19:1995;599-607.
    • (1995) Free Radic Biol Med , vol.19 , pp. 599-607
    • Mabile, L.1    Salvayre, R.2    Bonnafe, M.J.3    Negre-Salvayre, A.4
  • 41
    • 0025214470 scopus 로고
    • Decreased mitogenic activity in hypercholesterolaemic plasma
    • Mölgaard J., Carlsson M., Nilsson J., Olsson A.G. Decreased mitogenic activity in hypercholesterolaemic plasma. J Intern Med. 227:1990;339-345.
    • (1990) J Intern Med , vol.227 , pp. 339-345
    • Mölgaard, J.1    Carlsson, M.2    Nilsson, J.3    Olsson, A.G.4
  • 42
    • 0025695026 scopus 로고
    • Involvement of intracellular iron in the toxicity of oxidized low density lipoprotein to cultured endothelial cells
    • Kuzuya M., Naito M., Funaki C., Hayashi T., Asai K., Kuzuya F. Involvement of intracellular iron in the toxicity of oxidized low density lipoprotein to cultured endothelial cells. Biochem Int. 22:1990;567-573.
    • (1990) Biochem Int , vol.22 , pp. 567-573
    • Kuzuya, M.1    Naito, M.2    Funaki, C.3    Hayashi, T.4    Asai, K.5    Kuzuya, F.6
  • 43
    • 0028787428 scopus 로고
    • In vitro cell injury by oxidized low density lipoprotein involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals
    • Coffey M.D., Cole R.A., Colles S.M., Chisolm G.M. In vitro cell injury by oxidized low density lipoprotein involves lipid hydroperoxide-induced formation of alkoxyl, lipid, and peroxyl radicals. J Clin Invest. 96:1995;1866-1873.
    • (1995) J Clin Invest , vol.96 , pp. 1866-1873
    • Coffey, M.D.1    Cole, R.A.2    Colles, S.M.3    Chisolm, G.M.4
  • 44
    • 0028220687 scopus 로고
    • Cell death induced by peroxidized low-density lipoprotein: Endopepsis
    • Fossel E.T., Zanella C.L., Fletcher J.G., Hui K.K.S. Cell death induced by peroxidized low-density lipoprotein: endopepsis. Cancer Res. 54:1994;1240-1248.
    • (1994) Cancer Res , vol.54 , pp. 1240-1248
    • Fossel, E.T.1    Zanella, C.L.2    Fletcher, J.G.3    Hui, K.K.S.4
  • 45
    • 0028207078 scopus 로고
    • Apolipoprotein B of oxidized LDL accumulates in the lysosomes of macrophages
    • Mander E.L., Dean R.T., Stanley K.K., Jessup W. Apolipoprotein B of oxidized LDL accumulates in the lysosomes of macrophages. Biochim Biophys Acta. 1212:1994;80-92.
    • (1994) Biochim Biophys Acta , vol.1212 , pp. 80-92
    • Mander, E.L.1    Dean, R.T.2    Stanley, K.K.3    Jessup, W.4
  • 47
    • 0030474490 scopus 로고    scopus 로고
    • Foam cell apoptosis and the development of the lipid core of human atherosclerosis
    • Hegyi L., Skepper J.N., Cary N.R.B., Mitchinson M.J. Foam cell apoptosis and the development of the lipid core of human atherosclerosis. J Pathol. 180:1996;423-429.
    • (1996) J Pathol , vol.180 , pp. 423-429
    • Hegyi, L.1    Skepper, J.N.2    Cary, N.R.B.3    Mitchinson, M.J.4
  • 48
    • 0026696356 scopus 로고
    • Oxidized low density lipoproteins elicit DNA fragmentation of cultured lymphoblastoid cells
    • Escargueil I., Negre-Salvayre A., Pieraggi M.T., Salvayre R. Oxidized low density lipoproteins elicit DNA fragmentation of cultured lymphoblastoid cells. Biochim Biophys Acta. 305:1992;155-159.
    • (1992) Biochim Biophys Acta , vol.305 , pp. 155-159
    • Escargueil, I.1    Negre-Salvayre, A.2    Pieraggi, M.T.3    Salvayre, R.4
  • 50
    • 0029115152 scopus 로고
    • Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1β-converting enzyme
    • Geng Y.J., Libby P. Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1β-converting enzyme. Am J Pathol. 147:1995;251-266.
    • (1995) Am J Pathol , vol.147 , pp. 251-266
    • Geng, Y.J.1    Libby, P.2
  • 51
    • 0031004573 scopus 로고    scopus 로고
    • Oxidant-induced apoptosis: A consequence of lethal lysosomal leak?
    • Hellquist HB, Svensson I, Brunk UT. Oxidant-induced apoptosis: a consequence of lethal lysosomal leak? Redox Rep, 1997;3:65-70.
    • (1997) Redox Rep , vol.3 , pp. 65-70
    • Hellquist, H.B.1    Svensson, I.2    Brunk, U.T.3
  • 52
    • 0030757986 scopus 로고    scopus 로고
    • Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts
    • Brunk UT, Dalen H, Roberg K, Hellquist B. Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts. Free Radic Biol Med, 1997;23:616-626.
    • (1997) Free Radic Biol Med , vol.23 , pp. 616-626
    • Brunk, U.T.1    Dalen, H.2    Roberg, K.3    Hellquist, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.